GLI1 Gene Set

Dataset ChEA Transcription Factor Targets
Category genomics
Type transcription factor
Description GLI family zinc finger 1|This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 2735)
External Link http://www.ncbi.nlm.nih.gov/gene/2735
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Genes

63 target genes of the GLI1 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

Symbol Name
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADAM12 ADAM metallopeptidase domain 12
ADAMTSL1 ADAMTS-like 1
ASIC2 acid sensing (proton gated) ion channel 2
ASTN2 astrotactin 2
BNC2 basonuclin 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C6 complement component 6
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CDH7 cadherin 7, type 2
CDH8 cadherin 8, type 2
CDK14 cyclin-dependent kinase 14
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CSNK1G3 casein kinase 1, gamma 3
DCBLD1 discoidin, CUB and LCCL domain containing 1
EFTUD1 elongation factor Tu GTP binding domain containing 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERC2 ELKS/RAB6-interacting/CAST family member 2
FAM3C family with sequence similarity 3, member C
FHIT fragile histidine triad
FHL1 four and a half LIM domains 1
GOPC golgi-associated PDZ and coiled-coil motif containing
GPC3 glypican 3
GRIPAP1 GRIP1 associated protein 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HHIP hedgehog interacting protein
HMGN5 high mobility group nucleosome binding domain 5
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL6R interleukin 6 receptor
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
LAMP3 lysosomal-associated membrane protein 3
MUT methylmalonyl CoA mutase
NCAM1 neural cell adhesion molecule 1
NKX2-3 NK2 homeobox 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPAS3 neuronal PAS domain protein 3
NT5C1B 5'-nucleotidase, cytosolic IB
NTNG2 netrin G2
PABPC5 poly(A) binding protein, cytoplasmic 5
PARK2 parkin RBR E3 ubiquitin protein ligase
PDE4B phosphodiesterase 4B, cAMP-specific
PHF21A PHD finger protein 21A
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PITPNB phosphatidylinositol transfer protein, beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCE protein kinase C, epsilon
RAD51B RAD51 paralog B
RAI14 retinoic acid induced 14
RGMA repulsive guidance molecule family member a
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
ROR1 receptor tyrosine kinase-like orphan receptor 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC16A4 solute carrier family 16, member 4
SLC39A10 solute carrier family 39 (zinc transporter), member 10
TENM2 teneurin transmembrane protein 2
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TRPS1 trichorhinophalangeal syndrome I
UBE2DNL ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene)
UNC5D unc-5 homolog D (C. elegans)
UTRN utrophin
ZSWIM2 zinc finger, SWIM-type containing 2