| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | GLI family zinc finger 1|This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 2735) |
| External Link | https://ncbi.nlm.nih.gov/gene/2735 |
| Similar Terms | |
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499 genes differentially expressed following the GLI1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT5 | keratin 5, type II | 0.0203783 |
| CSTA | cystatin A (stefin A) | 0.0199767 |
| LTF | lactotransferrin | 0.0197876 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0186459 |
| KRT15 | keratin 15, type I | 0.0178308 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0178183 |
| S100A8 | S100 calcium binding protein A8 | 0.0174103 |
| KRT14 | keratin 14, type I | 0.0169255 |
| RGCC | regulator of cell cycle | 0.0159842 |
| TSPAN8 | tetraspanin 8 | 0.0158787 |
| TRIM29 | tripartite motif containing 29 | 0.0156968 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0156442 |
| S100P | S100 calcium binding protein P | 0.01561 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0155201 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.0153372 |
| FABP7 | fatty acid binding protein 7, brain | 0.0152926 |
| S100A9 | S100 calcium binding protein A9 | 0.015076 |
| S100A7 | S100 calcium binding protein A7 | 0.0147248 |
| AOC1 | amine oxidase, copper containing 1 | 0.0146914 |
| KRT19 | keratin 19, type I | 0.0145976 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0144735 |
| CLDN8 | claudin 8 | 0.0143102 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0140541 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.013857 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0136219 |
| LAMC2 | laminin, gamma 2 | 0.0134923 |
| CALB1 | calbindin 1, 28kDa | 0.0131192 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.013049 |
| S100A10 | S100 calcium binding protein A10 | 0.0126974 |
| RGS10 | regulator of G-protein signaling 10 | 0.0125243 |
| BCL2A1 | BCL2-related protein A1 | 0.0125176 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0123838 |
| MMP7 | matrix metallopeptidase 7 | 0.0122792 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0120656 |
| INHBA | inhibin, beta A | 0.0120373 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0120033 |
| FCGBP | Fc fragment of IgG binding protein | 0.0119528 |
| SPRR3 | small proline-rich protein 3 | 0.0118937 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0117024 |
| NEBL | nebulette | 0.0117 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0116676 |
| HEPH | hephaestin | 0.0116183 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0115264 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0115099 |
| ANXA1 | annexin A1 | 0.0115049 |
| KYNU | kynureninase | 0.0114968 |
| MSMB | microseminoprotein, beta- | 0.0114506 |
| ADD3 | adducin 3 (gamma) | 0.0114391 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0113137 |
| RCAN1 | regulator of calcineurin 1 | 0.011215 |
| PADI2 | peptidyl arginine deiminase, type II | 0.0110502 |
| CTSS | cathepsin S | 0.011019 |
| SPRR1B | small proline-rich protein 1B | 0.0109515 |
| KRT13 | keratin 13, type I | 0.0109191 |
| FERMT1 | fermitin family member 1 | 0.010884 |
| IRF6 | interferon regulatory factor 6 | 0.0108578 |
| LCN2 | lipocalin 2 | 0.0108412 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.0108308 |
| KRT6A | keratin 6A, type II | 0.0108164 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0108021 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0107322 |
| S100A2 | S100 calcium binding protein A2 | 0.0107056 |
| KRT23 | keratin 23, type I | 0.0106825 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0106392 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.0105934 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0105822 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0105737 |
| FAR2 | fatty acyl CoA reductase 2 | 0.0105283 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0104832 |
| MMP12 | matrix metallopeptidase 12 | 0.0104728 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.010422 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.0102741 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.0101734 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.0101662 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.0101605 |
| LPXN | leupaxin | 0.0101142 |
| TP63 | tumor protein p63 | 0.0100997 |
| DAXX | death-domain associated protein | 0.00997841 |
| PERP | PERP, TP53 apoptosis effector | 0.00996227 |
| SFN | stratifin | 0.00992734 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00992489 |
| GPX2 | glutathione peroxidase 2 | 0.00990014 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00983963 |
| RNASET2 | ribonuclease T2 | 0.00983744 |
| CST1 | cystatin SN | 0.00978503 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00978321 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00975273 |
| ITGB4 | integrin, beta 4 | 0.00970531 |
| KRT6B | keratin 6B, type II | 0.00967913 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00967692 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00964782 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00962024 |
| GPR137B | G protein-coupled receptor 137B | 0.00960229 |
| TFF1 | trefoil factor 1 | 0.00957278 |
| LXN | latexin | 0.00951291 |
| CAST | calpastatin | 0.00947964 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00947369 |
| EGR2 | early growth response 2 | 0.00946821 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00946099 |
| RAB29 | RAB29, member RAS oncogene family | 0.00936836 |
| MARCKSL1 | MARCKS-like 1 | 0.00936007 |
| INAVA | innate immunity activator | 0.0093473 |
| IL2RG | interleukin 2 receptor, gamma | 0.00933131 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00931405 |
| CTSH | cathepsin H | 0.0093101 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00925594 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0091321 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00910219 |
| PRKCA | protein kinase C, alpha | 0.0091011 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00909816 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00908473 |
| MAL | mal, T-cell differentiation protein | 0.00904131 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00899687 |
| IL1RN | interleukin 1 receptor antagonist | 0.00898427 |
| S100A14 | S100 calcium binding protein A14 | 0.0089354 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00887682 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.008857 |
| GUCY2C | guanylate cyclase 2C | 0.00885651 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00874456 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00874108 |
| MVP | major vault protein | 0.00873002 |
| TSPAN1 | tetraspanin 1 | 0.00868296 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00866131 |
| DPEP1 | dipeptidase 1 (renal) | 0.00865625 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00865387 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.0086075 |
| TSPYL5 | TSPY-like 5 | 0.00860142 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00857952 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00855963 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00853052 |
| ABLIM1 | actin binding LIM protein 1 | 0.00852815 |
| COCH | cochlin | 0.00852472 |
| SATB2 | SATB homeobox 2 | 0.00851577 |
| ATF3 | activating transcription factor 3 | 0.00851185 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0085017 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00848519 |
| GRAMD2B | GRAM domain containing 2B | 0.00847673 |
| CLCA4 | chloride channel accessory 4 | 0.00843467 |
| MYO1C | myosin IC | 0.00840711 |
| EPCAM | epithelial cell adhesion molecule | 0.00839812 |
| PLAU | plasminogen activator, urokinase | 0.00837625 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00836266 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.00832945 |
| KRT17 | keratin 17, type I | 0.00830166 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00829482 |
| LBH | limb bud and heart development | 0.0082894 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00828202 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00819923 |
| MX1 | MX dynamin-like GTPase 1 | 0.00819034 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00818433 |
| MME | membrane metallo-endopeptidase | 0.00818092 |
| CD86 | CD86 molecule | 0.0081683 |
| EMP1 | epithelial membrane protein 1 | 0.00816792 |
| NMD3 | NMD3 ribosome export adaptor | 0.0081495 |
| COBL | cordon-bleu WH2 repeat protein | 0.00812664 |
| MMP9 | matrix metallopeptidase 9 | 0.00811495 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00809605 |
| CLTB | clathrin, light chain B | 0.00808831 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00808706 |
| KIAA0226L | KIAA0226-like | 0.00808512 |
| IQCG | IQ motif containing G | 0.0080173 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00801515 |
| APOD | apolipoprotein D | 0.0079819 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00797917 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00795828 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00794814 |
| CHI3L2 | chitinase 3-like 2 | 0.00792322 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00791966 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00791886 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00788742 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00788512 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00787872 |
| FOSL2 | FOS-like antigen 2 | 0.00786443 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0078215 |
| HDDC2 | HD domain containing 2 | 0.00781415 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0077929 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00777103 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0077691 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00774593 |
| VSNL1 | visinin-like 1 | 0.0077445 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.0077401 |
| AREG | amphiregulin | 0.0077368 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00772108 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00768871 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00768349 |
| GOLT1B | golgi transport 1B | 0.00767198 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00763405 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00762794 |
| MGP | matrix Gla protein | 0.0076238 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00757439 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00756983 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0075496 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00751676 |
| LY86 | lymphocyte antigen 86 | 0.00748879 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00746972 |
| LETMD1 | LETM1 domain containing 1 | 0.00745626 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00743818 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00742338 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00742229 |
| PLEK2 | pleckstrin 2 | 0.00741635 |
| DSP | desmoplakin | 0.00741213 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00737208 |
| ZIC1 | Zic family member 1 | 0.00736942 |
| SPRR1A | small proline-rich protein 1A | 0.00736289 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00734622 |
| RAB25 | RAB25, member RAS oncogene family | 0.00733507 |
| LAD1 | ladinin 1 | 0.00732672 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00732115 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00731744 |
| CD9 | CD9 molecule | 0.00731414 |
| OPTN | optineurin | 0.00729995 |
| IL1B | interleukin 1, beta | 0.00729317 |
| TBX2 | T-box 2 | 0.00728439 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | 0.00727016 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00726474 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00726376 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00726156 |
| PKP1 | plakophilin 1 | 0.00725755 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00725362 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00724982 |
| PMP2 | peripheral myelin protein 2 | 0.00724626 |
| KRT20 | keratin 20, type I | 0.0072168 |
| STON1 | stonin 1 | 0.00717236 |
| KRT81 | keratin 81, type II | 0.0071672 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00715981 |
| TARP | TCR gamma alternate reading frame protein | 0.00715681 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00715592 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00714899 |
| AZIN1 | antizyme inhibitor 1 | 0.00713106 |
| TPD52L1 | tumor protein D52-like 1 | 0.00712093 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00707189 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | 0.00705019 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00704845 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00703319 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0070277 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00700963 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00700893 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00700303 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00699385 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00699244 |
| CSTB | cystatin B (stefin B) | 0.00696032 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00693816 |
| STK17A | serine/threonine kinase 17a | 0.00693811 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00689572 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00688745 |
| EDN3 | endothelin 3 | 0.00688486 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00685521 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00684672 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00681688 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0231172 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0210401 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0149785 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0141851 |
| CLU | clusterin | -0.0130722 |
| BCHE | butyrylcholinesterase | -0.0119866 |
| REEP1 | receptor accessory protein 1 | -0.0117391 |
| CPE | carboxypeptidase E | -0.0112068 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.0110578 |
| SST | somatostatin | -0.010973 |
| CCND1 | cyclin D1 | -0.0107915 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0107405 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0105235 |
| DCLK1 | doublecortin-like kinase 1 | -0.0101682 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0100216 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.0100062 |
| HELLS | helicase, lymphoid-specific | -0.0099957 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00989884 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00975274 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00968395 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00954351 |
| FGG | fibrinogen gamma chain | -0.00949566 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.0094868 |
| MMP2 | matrix metallopeptidase 2 | -0.00934035 |
| ACKR3 | atypical chemokine receptor 3 | -0.00927363 |
| ZNF160 | zinc finger protein 160 | -0.00923124 |
| TMSB15A | thymosin beta 15a | -0.00919235 |
| CD320 | CD320 molecule | -0.00908444 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00901706 |
| RAPSN | receptor-associated protein of the synapse | -0.00898736 |
| FRZB | frizzled-related protein | -0.00898495 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00896336 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00896146 |
| RGS5 | regulator of G-protein signaling 5 | -0.0089585 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00893349 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00892854 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00886235 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00880602 |
| FAM13A | family with sequence similarity 13, member A | -0.0087789 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00870586 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00869037 |
| CRLF1 | cytokine receptor-like factor 1 | -0.0086885 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00858631 |
| PRR11 | proline rich 11 | -0.00855679 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00852137 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00850208 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00848607 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00839974 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00839458 |
| PXDN | peroxidasin | -0.00838726 |
| C6 | complement component 6 | -0.00834032 |
| NNMT | nicotinamide N-methyltransferase | -0.00828877 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00827873 |
| CALCA | calcitonin-related polypeptide alpha | -0.00825148 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00822599 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00820566 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00812849 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00811127 |
| FSTL1 | follistatin-like 1 | -0.0081043 |
| TSPAN12 | tetraspanin 12 | -0.0080851 |
| CLGN | calmegin | -0.00807397 |
| LRRC17 | leucine rich repeat containing 17 | -0.00802268 |
| PRDX2 | peroxiredoxin 2 | -0.00798871 |
| FOXF1 | forkhead box F1 | -0.00796 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00770646 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00769595 |
| PFAS | phosphoribosylformylglycinamidine synthase | -0.00769245 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00766973 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00766681 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0076369 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00761696 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00761391 |
| ELAC2 | elaC ribonuclease Z 2 | -0.00759668 |
| AURKB | aurora kinase B | -0.00755879 |
| FGA | fibrinogen alpha chain | -0.00755168 |
| WWC3 | WWC family member 3 | -0.00754956 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00754706 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00753685 |
| HHEX | hematopoietically expressed homeobox | -0.00752967 |
| CLSTN2 | calsyntenin 2 | -0.0075125 |
| ENO3 | enolase 3 (beta, muscle) | -0.00750502 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00749349 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00749207 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00747847 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00746158 |
| FASN | fatty acid synthase | -0.00745126 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | -0.00742073 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00738699 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00736524 |
| TK1 | thymidine kinase 1, soluble | -0.00734529 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00732593 |
| PLIN1 | perilipin 1 | -0.00728925 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00728009 |
| DAPK1 | death-associated protein kinase 1 | -0.00725 |
| ZNF721 | zinc finger protein 721 | -0.00724522 |
| CRP | C-reactive protein, pentraxin-related | -0.00721878 |
| FRY | furry homolog (Drosophila) | -0.00716872 |
| CSK | c-src tyrosine kinase | -0.00716564 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00714513 |
| GNAS | GNAS complex locus | -0.00714382 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00712926 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00712924 |
| SNX7 | sorting nexin 7 | -0.00712716 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0071192 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00709049 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00709025 |
| PCGF3 | polycomb group ring finger 3 | -0.00706252 |
| MSX1 | msh homeobox 1 | -0.00706079 |
| CDK11A | cyclin-dependent kinase 11A | -0.00704038 |
| NXN | nucleoredoxin | -0.00703924 |
| AMOTL2 | angiomotin like 2 | -0.00703498 |
| C9 | complement component 9 | -0.00702937 |
| WDR7 | WD repeat domain 7 | -0.00702718 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00700385 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0070009 |
| H1-0 | H1.0 linker histone | -0.00698676 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00697523 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00697489 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.0069629 |
| F9 | coagulation factor IX | -0.0069359 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00690685 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00686591 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00685192 |
| CDC20 | cell division cycle 20 | -0.00685141 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00684347 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00684214 |
| SRM | spermidine synthase | -0.00679405 |
| FZD2 | frizzled class receptor 2 | -0.00678644 |
| RTL8C | retrotransposon Gag like 8C | -0.00678169 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00678062 |
| FAM110B | family with sequence similarity 110, member B | -0.00677409 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00677249 |
| NBEA | neurobeachin | -0.00676689 |
| FHL1 | four and a half LIM domains 1 | -0.00675987 |
| USP22 | ubiquitin specific peptidase 22 | -0.00673386 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0067333 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00669522 |
| OLFM1 | olfactomedin 1 | -0.00669378 |
| EMP3 | epithelial membrane protein 3 | -0.00668544 |
| ORM1 | orosomucoid 1 | -0.00668528 |
| CRIP2 | cysteine-rich protein 2 | -0.00667844 |
| IPO9 | importin 9 | -0.00664185 |
| ESYT1 | extended synaptotagmin-like protein 1 | -0.00663275 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00661994 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00660734 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00660122 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.00658748 |
| SEPTIN10 | septin 10 | -0.00658729 |
| THBS4 | thrombospondin 4 | -0.00658578 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0065768 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00657404 |
| TCERG1 | transcription elongation regulator 1 | -0.00655777 |
| SLBP | stem-loop binding protein | -0.00655462 |
| RBPMS | RNA binding protein with multiple splicing | -0.00655274 |
| BAD | BCL2-associated agonist of cell death | -0.00654954 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00653899 |
| DVL1 | dishevelled segment polarity protein 1 | -0.00653483 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | -0.00653373 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00651587 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00649026 |
| JADE1 | jade family PHD finger 1 | -0.0064823 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00644448 |
| PMM2 | phosphomannomutase 2 | -0.00644313 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -0.00643597 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0064259 |
| APOC3 | apolipoprotein C-III | -0.0064236 |
| GPX3 | glutathione peroxidase 3 | -0.00642205 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00641475 |
| TGFB1 | transforming growth factor, beta 1 | -0.00641105 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00640311 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00639815 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.00638386 |
| APOB | apolipoprotein B | -0.00638136 |
| G0S2 | G0/G1 switch 2 | -0.00632868 |
| LIN28A | lin-28 homolog A (C. elegans) | -0.00631469 |
| NPY | neuropeptide Y | -0.00630815 |
| TYMS | thymidylate synthetase | -0.00629243 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0062896 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00628378 |
| PNN | pinin, desmosome associated protein | -0.00628295 |
| CBS | cystathionine-beta-synthase | -0.00627227 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.0062674 |
| REC8 | REC8 meiotic recombination protein | -0.00626262 |
| BARX1 | BARX homeobox 1 | -0.0062516 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.00625112 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | -0.00624908 |
| DPT | dermatopontin | -0.00624656 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00624074 |
| MYO5C | myosin VC | -0.00623953 |
| NAV2 | neuron navigator 2 | -0.00623879 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00623127 |
| RXRA | retinoid X receptor, alpha | -0.00622354 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00622207 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00621712 |
| UBAP2L | ubiquitin associated protein 2-like | -0.00621471 |
| RPA1 | replication protein A1, 70kDa | -0.00621158 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00619565 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0061886 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00618503 |
| FGL1 | fibrinogen-like 1 | -0.00617399 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00614534 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00614126 |
| MRPL20 | mitochondrial ribosomal protein L20 | -0.00613812 |
| HAL | histidine ammonia-lyase | -0.00613784 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | -0.00613517 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00612414 |
| TARDBP | TAR DNA binding protein | -0.00611081 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | -0.00610093 |
| PCLAF | PCNA clamp associated factor | -0.00609094 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.0060746 |
| ELN | elastin | -0.00606508 |
| KIF18B | kinesin family member 18B | -0.00606156 |
| TIMELESS | timeless circadian clock | -0.00606128 |
| NKTR | natural killer cell triggering receptor | -0.00605728 |
| PDZRN4 | PDZ domain containing ring finger 4 | -0.00605236 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00603949 |
| LPAR2 | lysophosphatidic acid receptor 2 | -0.00603403 |
| MAEA | macrophage erythroblast attacher | -0.00603271 |
| CCNL2 | cyclin L2 | -0.00603034 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00602641 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00602563 |
| ANXA10 | annexin A10 | -0.00602175 |
| FLNC | filamin C, gamma | -0.00602023 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00601333 |
| SDC3 | syndecan 3 | -0.00600321 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | -0.00599752 |
| CP | ceruloplasmin (ferroxidase) | -0.00599241 |
| NMU | neuromedin U | -0.00598743 |
| NRSN2 | neurensin 2 | -0.00598476 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00597655 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00596538 |
| TMEM165 | transmembrane protein 165 | -0.00596351 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00595588 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00594616 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | -0.00594511 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00593671 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00592844 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00592416 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00591558 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | -0.00591066 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00590867 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00590083 |
| RYBP | RING1 and YY1 binding protein | -0.00589442 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00589328 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00588836 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00588832 |
| TRRAP | transformation/transcription domain-associated protein | -0.0058758 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -0.00587152 |
| ACACB | acetyl-CoA carboxylase beta | -0.00586729 |
| CERS4 | ceramide synthase 4 | -0.00586307 |
