GLI1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description GLI family zinc finger 1|This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 2735)
External Link http://www.ncbi.nlm.nih.gov/gene/2735
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67 interacting proteins for GLI1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CDK4 cyclin-dependent kinase 4
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1E casein kinase 1, epsilon
CUL1 cullin 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
FEM1B fem-1 homolog b (C. elegans)
FUZ fuzzy planar cell polarity protein
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC8 histone deacetylase 8
IFT122 intraflagellar transport 122
IFT172 intraflagellar transport 172
IFT52 intraflagellar transport 52
IFT57 intraflagellar transport 57
IFT88 intraflagellar transport 88
INTU inturned planar cell polarity protein
ITCH itchy E3 ubiquitin protein ligase
KIF3A kinesin family member 3A
KIF7 kinesin family member 7
MKS1 Meckel syndrome, type 1
NUMB numb homolog (Drosophila)
OFD1 oral-facial-digital syndrome 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCI protein kinase C, iota
PTCH1 patched 1
RAI1 retinoic acid induced 1
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPGRIP1L RPGRIP1-like
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SAP18 Sin3A-associated protein, 18kDa
SAP30 Sin3A-associated protein, 30kDa
SHH sonic hedgehog
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SKP1 S-phase kinase-associated protein 1
SMO smoothened, frizzled class receptor
STK36 serine/threonine kinase 36
SUFU suppressor of fused homolog (Drosophila)
TTC21B tetratricopeptide repeat domain 21B
UBC ubiquitin C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XBP1 X-box binding protein 1
XPO1 exportin 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZIC1 Zic family member 1
ZIC2 Zic family member 2