GLI1_UP.V1 Gene Set

Dataset MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations
Category transcriptomics
Type gene perturbation
Description gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GLI1_UP.V1_UP
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Genes

56 genes differentially expressed following the GLI1_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.

increased expression

Symbol Name
C16ORF45 chromosome 16 open reading frame 45
C7ORF50 chromosome 7 open reading frame 50
CCND2 cyclin D2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
FEM1A fem-1 homolog a (C. elegans)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFT74 intraflagellar transport 74
IGFBP6 insulin-like growth factor binding protein 6
JCHAIN joining chain of multimeric IgA and IgM
LMO7 LIM domain 7
M6PR mannose-6-phosphate receptor (cation dependent)
PLXNA2 plexin A2
POFUT2 protein O-fucosyltransferase 2
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPT2 palmitoyl-protein thioesterase 2
PRKD3 protein kinase D3
PTH1R parathyroid hormone 1 receptor
SAR1A secretion associated, Ras related GTPase 1A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
STAU1 staufen double-stranded RNA binding protein 1
TMOD3 tropomodulin 3 (ubiquitous)
TRIM23 tripartite motif containing 23
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
WEE1 WEE1 G2 checkpoint kinase
YBX1 Y box binding protein 1
ZBTB16 zinc finger and BTB domain containing 16
ZC3H18 zinc finger CCCH-type containing 18

decreased expression

Symbol Name
ACSL6 acyl-CoA synthetase long-chain family member 6
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
BBX bobby sox homolog (Drosophila)
BTBD16 BTB (POZ) domain containing 16
CACUL1 CDK2-associated, cullin domain 1
CCNL2 cyclin L2
CD2AP CD2-associated protein
COPZ1 coatomer protein complex, subunit zeta 1
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
ESYT1 extended synaptotagmin-like protein 1
FOLR1 folate receptor 1 (adult)
GTDC1 glycosyltransferase-like domain containing 1
LIN37 lin-37 DREAM MuvB core complex component
OPN3 opsin 3
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
QRICH2 glutamine rich 2
RNF10 ring finger protein 10
RSAD2 radical S-adenosyl methionine domain containing 2
RUNX1 runt-related transcription factor 1
SELM selenoprotein M
SEPT9 septin 9
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
TLDC2 TBC/LysM-associated domain containing 2
TMEM181 transmembrane protein 181
TMEM189 transmembrane protein 189
TMEM62 transmembrane protein 62
YIPF1 Yip1 domain family, member 1
ZMYND11 zinc finger, MYND-type containing 11