GLI2 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description GLI family zinc finger 2|This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2736)
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Genes

80 target genes of the GLI2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAR adenosine deaminase, RNA-specific
ADGRG6 adhesion G protein-coupled receptor G6
ADGRL3 adhesion G protein-coupled receptor L3
ADK adenosine kinase
AIM1L absent in melanoma 1-like
AKAP13 A kinase (PRKA) anchor protein 13
ARHGAP33 Rho GTPase activating protein 33
ARL5B ADP-ribosylation factor-like 5B
ASIC4 acid sensing (proton gated) ion channel family member 4
BAHD1 bromo adjacent homology domain containing 1
CA14 carbonic anhydrase XIV
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTNAP1 contactin associated protein 1
CXXC5 CXXC finger protein 5
DUSP7 dual specificity phosphatase 7
ELMOD3 ELMO/CED-12 domain containing 3
ERF Ets2 repressor factor
EXTL3 exostosin-like glycosyltransferase 3
FNDC1 fibronectin type III domain containing 1
FOXL1 forkhead box L1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GGT7 gamma-glutamyltransferase 7
GHR growth hormone receptor
GLI1 GLI family zinc finger 1
GTF2IRD1 GTF2I repeat domain containing 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HES1 hes family bHLH transcription factor 1
HMCN1 hemicentin 1
HOXD12 homeobox D12
IER5L immediate early response 5-like
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
ISOC1 isochorismatase domain containing 1
JARID2 jumonji, AT rich interactive domain 2
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
LOC100128176 uncharacterized LOC100128176
LOC643355 uncharacterized LOC643355
LPCAT3 lysophosphatidylcholine acyltransferase 3
LYPD6 LY6/PLAUR domain containing 6
MAP7D1 MAP7 domain containing 1
MAT2A methionine adenosyltransferase II, alpha
MIR3193 microRNA 3193
MIR96 microRNA 96
NAV3 neuron navigator 3
NTN1 netrin 1
NTN3 netrin 3
NUP35 nucleoporin 35kDa
NUP37 nucleoporin 37kDa
ODF2 outer dense fiber of sperm tails 2
PACRG PARK2 co-regulated
PCDHGA2 protocadherin gamma subfamily A, 2
PEBP1 phosphatidylethanolamine binding protein 1
PRDM8 PR domain containing 8
PRR3 proline rich 3
PRUNE2 prune homolog 2 (Drosophila)
RAB37 RAB37, member RAS oncogene family
RAI14 retinoic acid induced 14
SAMD1 sterile alpha motif domain containing 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERGEF secretion regulating guanine nucleotide exchange factor
SH3BP1 SH3-domain binding protein 1
SLC26A10 solute carrier family 26, member 10
SLC35F6 solute carrier family 35, member F6
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOX8 SRY (sex determining region Y)-box 8
SUFU suppressor of fused homolog (Drosophila)
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TENM3 teneurin transmembrane protein 3
TGIF2 TGFB-induced factor homeobox 2
TGIF2-C20ORF24 TGIF2-C20orf24 readthrough
THADA thyroid adenoma associated
THRAP3 thyroid hormone receptor associated protein 3
TMEM256 transmembrane protein 256
TMEM92 transmembrane protein 92
TYROBP TYRO protein tyrosine kinase binding protein
UNC80 unc-80 homolog (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
ZNF362 zinc finger protein 362