GMPS Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description guanine monphosphate synthase|In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8833)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_GMPS
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Genes

53 co-expressed genes for GMPS from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ACOT13 acyl-CoA thioesterase 13
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
BUB3 BUB3 mitotic checkpoint protein
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDK4 cyclin-dependent kinase 4
CHERP calcium homeostasis endoplasmic reticulum protein
CSNK2B casein kinase 2, beta polypeptide
CYCS cytochrome c, somatic
DARS aspartyl-tRNA synthetase
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
EIF3C eukaryotic translation initiation factor 3, subunit C
ERP29 endoplasmic reticulum protein 29
GMPS guanine monphosphate synthase
H2AFZ H2A histone family, member Z
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HCCS holocytochrome c synthase
HDDC2 HD domain containing 2
HSPA9 heat shock 70kDa protein 9 (mortalin)
IRAK1 interleukin-1 receptor-associated kinase 1
KIAA0101 KIAA0101
LMNB2 lamin B2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MTDH metadherin
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUP205 nucleoporin 205kDa
PARK7 parkinson protein 7
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD23A RAD23 homolog A (S. cerevisiae)
RFC2 replication factor C (activator 1) 2, 40kDa
SCAMP3 secretory carrier membrane protein 3
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SMC3 structural maintenance of chromosomes 3
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SRSF9 serine/arginine-rich splicing factor 9
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
UQCRC1 ubiquinol-cytochrome c reductase core protein I
VAMP7 vesicle-associated membrane protein 7
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2