GMS-10 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: glioblastoma (Cell Line Ontology, CLO_0003547)
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Genes

322 genes with high or low expression in GMS-10 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
KALRN kalirin, RhoGEF kinase 3.59631
PTPN11 protein tyrosine phosphatase, non-receptor type 11 2.97251
JPH2 junctophilin 2 2.66246
BTN2A1 butyrophilin, subfamily 2, member A1 2.60924
AVEN apoptosis, caspase activation inhibitor 2.58684
KIF23 kinesin family member 23 2.29693
DPY19L4 dpy-19-like 4 (C. elegans) 2.26266
ACTN1 actinin, alpha 1 2.20714
KCTD9 potassium channel tetramerization domain containing 9 2.09025
AOX1 aldehyde oxidase 1 2.06287
PVRL3 poliovirus receptor-related 3 2.05059
PVR poliovirus receptor 2.03974
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.02662
RBM23 RNA binding motif protein 23 1.97662
CA3 carbonic anhydrase III 1.96673
DEK DEK proto-oncogene 1.9622
SOX3 SRY (sex determining region Y)-box 3 1.92158
EXTL3 exostosin-like glycosyltransferase 3 1.86015
TMX1 thioredoxin-related transmembrane protein 1 1.85439
SOAT1 sterol O-acyltransferase 1 1.83233
SH2D4A SH2 domain containing 4A 1.81306
IMPAD1 inositol monophosphatase domain containing 1 1.79061
TRIP11 thyroid hormone receptor interactor 11 1.78306
LRP12 low density lipoprotein receptor-related protein 12 1.77525
USP8 ubiquitin specific peptidase 8 1.76866
FOXG1 forkhead box G1 1.76356
CNN2 calponin 2 1.75449
ACTG2 actin, gamma 2, smooth muscle, enteric 1.73993
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 1.73305
ERH enhancer of rudimentary homolog (Drosophila) 1.72785
ACYP2 acylphosphatase 2, muscle type 1.69172
CDCA4 cell division cycle associated 4 1.67996
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.66915
SPHK1 sphingosine kinase 1 1.66757
CDC5L cell division cycle 5-like 1.66282
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.6581
ATXN2 ataxin 2 1.63972
OSGEP O-sialoglycoprotein endopeptidase 1.62872
EDN1 endothelin 1 1.58297
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.57117
SNX16 sorting nexin 16 1.54713
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 1.54647
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.54294
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.53573
TPX2 TPX2, microtubule-associated 1.53
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.51617
DZIP1 DAZ interacting zinc finger protein 1 1.50859
CENPB centromere protein B, 80kDa 1.49474
ARSJ arylsulfatase family, member J 1.48985
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.48824
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 1.48578
COTL1 coactosin-like F-actin binding protein 1 1.48364
SPDL1 spindle apparatus coiled-coil protein 1 1.48252
RBM19 RNA binding motif protein 19 1.47866
CORO1C coronin, actin binding protein, 1C 1.47845
PTPRG protein tyrosine phosphatase, receptor type, G 1.46994
AFF4 AF4/FMR2 family, member 4 1.46585
TBX4 T-box 4 1.46325
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 1.4613
NKX3-1 NK3 homeobox 1 1.46056
CTGF connective tissue growth factor 1.45553
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 1.44863
RIF1 replication timing regulatory factor 1 1.44662
SFMBT1 Scm-like with four mbt domains 1 1.44582
THBS1 thrombospondin 1 1.43786
MAPKAP1 mitogen-activated protein kinase associated protein 1 1.42729
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 1.42404
PBK PDZ binding kinase 1.42203
ILK integrin-linked kinase 1.42037
MYL9 myosin, light chain 9, regulatory 1.41661

low expression

Symbol Name Standardized Value
LETMD1 LETM1 domain containing 1 -3.31959
CLDN5 claudin 5 -2.95146
GRIK5 glutamate receptor, ionotropic, kainate 5 -2.94986
MDFI MyoD family inhibitor -2.93941
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 -2.90826
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 -2.89148
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 -2.82821
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -2.80786
STMN3 stathmin-like 3 -2.76922
IFNA17 interferon, alpha 17 -2.74717
NEK3 NIMA-related kinase 3 -2.73135
GPATCH4 G patch domain containing 4 -2.67231
CALY calcyon neuron-specific vesicular protein -2.65686
GJD2 gap junction protein, delta 2, 36kDa -2.655
S1PR5 sphingosine-1-phosphate receptor 5 -2.65484
ICOSLG inducible T-cell co-stimulator ligand -2.65303
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -2.60116
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.60116
IFNA6 interferon, alpha 6 -2.57195
GRPR gastrin-releasing peptide receptor -2.56214
MMP8 matrix metallopeptidase 8 -2.48074
PROC protein C (inactivator of coagulation factors Va and VIIIa) -2.4267
KIAA0485 uncharacterized LOC57235 -2.37637
ZIC4 Zic family member 4 -2.36948
TRAPPC6A trafficking protein particle complex 6A -2.3609
DEFA4 defensin, alpha 4, corticostatin -2.35638
PLA1A phospholipase A1 member A -2.35031
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.29724
QPCT glutaminyl-peptide cyclotransferase -2.29187
GCLC glutamate-cysteine ligase, catalytic subunit -2.29124
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 -2.27832
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -2.26878
ACRV1 acrosomal vesicle protein 1 -2.26147
RAD52 RAD52 homolog (S. cerevisiae) -2.25653
CAV3 caveolin 3 -2.25214
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding) -2.21037
PAPOLG poly(A) polymerase gamma -2.2074
FZD9 frizzled class receptor 9 -2.20631
ENOSF1 enolase superfamily member 1 -2.19824
ZG16 zymogen granule protein 16 -2.19652
SLURP1 secreted LY6/PLAUR domain containing 1 -2.19203
SH2D3C SH2 domain containing 3C -2.18313
EIF3L eukaryotic translation initiation factor 3, subunit L -2.1704
ZNRF4 zinc and ring finger 4 -2.16287
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I -2.16179
CDH20 cadherin 20, type 2 -2.16007
ADAM11 ADAM metallopeptidase domain 11 -2.15565
GPR31 G protein-coupled receptor 31 -2.15069
RIMS3 regulating synaptic membrane exocytosis 3 -2.0742
IL22 interleukin 22 -2.04068
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -2.03544
RPLP0 ribosomal protein, large, P0 -2.02883
BEAN1 brain expressed, associated with NEDD4, 1 -2.02835
HPX hemopexin -2.02569
GIP gastric inhibitory polypeptide -2.02367
HHCM Mahlavu hepatocellular carcinoma -2.01013
MXI1 MAX interactor 1, dimerization protein -2.00784
CRYBA1 crystallin, beta A1 -1.99781
C5AR2 complement component 5a receptor 2 -1.99497
CS citrate synthase -1.99451
IAPP islet amyloid polypeptide -1.99447
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.95838
SCD stearoyl-CoA desaturase (delta-9-desaturase) -1.95199
ZFR2 zinc finger RNA binding protein 2 -1.9499
HPS4 Hermansky-Pudlak syndrome 4 -1.94
COPZ1 coatomer protein complex, subunit zeta 1 -1.93709
CHIT1 chitinase 1 (chitotriosidase) -1.93388
MPPED1 metallophosphoesterase domain containing 1 -1.92595
ZNF384 zinc finger protein 384 -1.92025
ACR acrosin -1.91613
MAP2 microtubule-associated protein 2 -1.91354
HIRA histone cell cycle regulator -1.91159
POLR1D polymerase (RNA) I polypeptide D, 16kDa -1.89912
MED12 mediator complex subunit 12 -1.89164
LONP2 lon peptidase 2, peroxisomal -1.88342
PDIA2 protein disulfide isomerase family A, member 2 -1.88145
TRAT1 T cell receptor associated transmembrane adaptor 1 -1.87779
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -1.87748
PEX1 peroxisomal biogenesis factor 1 -1.87738
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 -1.86935
TYROBP TYRO protein tyrosine kinase binding protein -1.86917
CD79A CD79a molecule, immunoglobulin-associated alpha -1.85983
TLR2 toll-like receptor 2 -1.85908
TMC6 transmembrane channel-like 6 -1.85099
CELF3 CUGBP, Elav-like family member 3 -1.85061
R3HDM2 R3H domain containing 2 -1.84917
SPINK4 serine peptidase inhibitor, Kazal type 4 -1.8302
GLUD1 glutamate dehydrogenase 1 -1.82696
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -1.82416
HIST3H2A histone cluster 3, H2a -1.81972
UFM1 ubiquitin-fold modifier 1 -1.81922
HAPLN2 hyaluronan and proteoglycan link protein 2 -1.81756
GNLY granulysin -1.81677
LTB4R2 leukotriene B4 receptor 2 -1.81598
HYAL1 hyaluronoglucosaminidase 1 -1.8144
OR3A1 olfactory receptor, family 3, subfamily A, member 1 -1.81117
MYOG myogenin (myogenic factor 4) -1.80778
UPB1 ureidopropionase, beta -1.7995
RHCE Rh blood group, CcEe antigens -1.79721
PAN2 PAN2 poly(A) specific ribonuclease subunit -1.78177
N4BP2L1 NEDD4 binding protein 2-like 1 -1.78055
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -1.77785
TBX21 T-box 21 -1.77073
ATP10A ATPase, class V, type 10A -1.76984
OBP2A odorant binding protein 2A -1.76786
GIMAP4 GTPase, IMAP family member 4 -1.7641
NACA nascent polypeptide-associated complex alpha subunit -1.7586
GPR25 G protein-coupled receptor 25 -1.75835
STAT4 signal transducer and activator of transcription 4 -1.75732
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -1.75587
PTCD1 pentatricopeptide repeat domain 1 -1.75538
TTC22 tetratricopeptide repeat domain 22 -1.75299
PAX3 paired box 3 -1.75231
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 -1.75162
NHLH2 nescient helix loop helix 2 -1.74648
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa -1.74497
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -1.74114
KRT76 keratin 76, type II -1.74102
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.74095
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 -1.73766
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.73496
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 -1.73361
SND1 staphylococcal nuclease and tudor domain containing 1 -1.73266
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.73123
CD3E CD3e molecule, epsilon (CD3-TCR complex) -1.73077
NLGN3 neuroligin 3 -1.72615
BEST2 bestrophin 2 -1.7253
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -1.72386
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -1.72232
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -1.71704
CD84 CD84 molecule -1.70934
FSHB follicle stimulating hormone, beta polypeptide -1.70636
NF1 neurofibromin 1 -1.70016
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -1.69361
ANKMY1 ankyrin repeat and MYND domain containing 1 -1.69297
EXTL1 exostosin-like glycosyltransferase 1 -1.68563
MKRN1 makorin ring finger protein 1 -1.68428
PRODH2 proline dehydrogenase (oxidase) 2 -1.68149
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 -1.67787
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -1.67194
TNNI2 troponin I type 2 (skeletal, fast) -1.67132
OGN osteoglycin -1.67125
INO80B INO80 complex subunit B -1.66957
WFDC1 WAP four-disulfide core domain 1 -1.66222
METTL8 methyltransferase like 8 -1.65917
DEF6 differentially expressed in FDCP 6 homolog (mouse) -1.65409
AQP8 aquaporin 8 -1.65355
LAMA1 laminin, alpha 1 -1.65198
GPX5 glutathione peroxidase 5 -1.65019
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -1.64263
GRIA2 glutamate receptor, ionotropic, AMPA 2 -1.6402
ABAT 4-aminobutyrate aminotransferase -1.63871
HHLA2 HERV-H LTR-associating 2 -1.63856
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.63841
PKNOX1 PBX/knotted 1 homeobox 1 -1.6323
ACSBG2 acyl-CoA synthetase bubblegum family member 2 -1.6318
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -1.62842
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -1.62649
GHITM growth hormone inducible transmembrane protein -1.62647
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -1.62414
XPOT exportin, tRNA -1.62331
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -1.62187
FN3K fructosamine 3 kinase -1.62129
APOC3 apolipoprotein C-III -1.62073
MCM3AP-AS1 MCM3AP antisense RNA 1 -1.6207
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -1.6205
HGFAC HGF activator -1.6179
CEP290 centrosomal protein 290kDa -1.6153
H2AFY2 H2A histone family, member Y2 -1.61362
DOCK5 dedicator of cytokinesis 5 -1.61156
LOC202181 SUMO-interacting motifs containing 1 pseudogene -1.60671
RAP1GAP RAP1 GTPase activating protein -1.60475
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -1.60341
SOX1 SRY (sex determining region Y)-box 1 -1.6028
ITGB7 integrin, beta 7 -1.59464
APLNR apelin receptor -1.59286
CCDC68 coiled-coil domain containing 68 -1.59206
ITGB6 integrin, beta 6 -1.59113
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -1.58977
CEP41 centrosomal protein 41kDa -1.58808
IGFLR1 IGF-like family receptor 1 -1.58379
GSTA3 glutathione S-transferase alpha 3 -1.57794
RUNDC3B RUN domain containing 3B -1.57744
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -1.57662
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -1.57626
RPS12 ribosomal protein S12 -1.5715
EIF3D eukaryotic translation initiation factor 3, subunit D -1.57066
WNT7A wingless-type MMTV integration site family, member 7A -1.56337
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -1.56204
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -1.56142
RAVER2 ribonucleoprotein, PTB-binding 2 -1.56
HNF1B HNF1 homeobox B -1.55647
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -1.55566
UPK3A uroplakin 3A -1.54694
TCL1A T-cell leukemia/lymphoma 1A -1.5432
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -1.54026
SLC44A4 solute carrier family 44, member 4 -1.54014
DDIT4 DNA-damage-inducible transcript 4 -1.52971
ZNF215 zinc finger protein 215 -1.52952
FAM35A family with sequence similarity 35, member A -1.5251
RBP3 retinol binding protein 3, interstitial -1.52483
CDX4 caudal type homeobox 4 -1.52443
ICA1 islet cell autoantigen 1, 69kDa -1.52083
PRY PTPN13-like, Y-linked -1.52043
GPR182 G protein-coupled receptor 182 -1.52005
SRI sorcin -1.51905
PRR13 proline rich 13 -1.51888
SCT secretin -1.51859
RUNDC3A RUN domain containing 3A -1.51394
SIDT1 SID1 transmembrane family, member 1 -1.51283
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) -1.50901
MYCNOS MYCN opposite strand -1.50895
TBXAS1 thromboxane A synthase 1 (platelet) -1.50767
LRRC8B leucine rich repeat containing 8 family, member B -1.50498
TIPRL TOR signaling pathway regulator -1.50493
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.50314
PTH parathyroid hormone -1.49869
T T, brachyury homolog (mouse) -1.49851
PAX7 paired box 7 -1.49507
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -1.48499
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -1.47966
TNNT2 troponin T type 2 (cardiac) -1.4753
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma -1.47139
CSF3R colony stimulating factor 3 receptor (granulocyte) -1.46363
CCR6 chemokine (C-C motif) receptor 6 -1.46342
CLDN14 claudin 14 -1.46304
MGEA5 meningioma expressed antigen 5 (hyaluronidase) -1.46241
ZNF695 zinc finger protein 695 -1.45742
KRT4 keratin 4, type II -1.4529
FAM192A family with sequence similarity 192, member A -1.45246
GSDMB gasdermin B -1.45161
CIDEA cell death-inducing DFFA-like effector a -1.45129
TRHR thyrotropin-releasing hormone receptor -1.45006
PDE1B phosphodiesterase 1B, calmodulin-dependent -1.44979
APOM apolipoprotein M -1.4462
DNAAF1 dynein, axonemal, assembly factor 1 -1.44443
HAND1 heart and neural crest derivatives expressed 1 -1.44391
RAB4B RAB4B, member RAS oncogene family -1.44003
SOX18 SRY (sex determining region Y)-box 18 -1.43837
GGTLC2 gamma-glutamyltransferase light chain 2 -1.43837
RDH16 retinol dehydrogenase 16 (all-trans) -1.43772
WNT4 wingless-type MMTV integration site family, member 4 -1.43463
DCAF10 DDB1 and CUL4 associated factor 10 -1.43272
LOC284244 uncharacterized LOC284244 -1.43242
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -1.43235
CHN2 chimerin 2 -1.43184
UPK1A uroplakin 1A -1.42338
IFNA10 interferon, alpha 10 -1.42297
KLRF1 killer cell lectin-like receptor subfamily F, member 1 -1.42241
MTNR1B melatonin receptor 1B -1.42189
CBR4 carbonyl reductase 4 -1.42066
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit -1.41892