GNE-477 Gene Set
Genes
26 genes differentially expressed following the GNE-477 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EGFR
|
epidermal growth factor receptor
|
5.60672
|
|
IGBP1
|
immunoglobulin (CD79A) binding protein 1
|
4.51688
|
|
SYF2
|
SYF2 pre-mRNA-splicing factor
|
4.3622
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.60029
|
|
EGR1
|
early growth response 1
|
3.55554
|
|
EIF3F
|
eukaryotic translation initiation factor 3, subunit F
|
3.53697
|
|
FXR1
|
fragile X mental retardation, autosomal homolog 1
|
3.46688
|
|
NOP53
|
NOP53 ribosome biogenesis factor
|
3.45408
|
|
LETMD1
|
LETM1 domain containing 1
|
3.37062
|
|
EIF4B
|
eukaryotic translation initiation factor 4B
|
3.342
|
|
ZBTB16
|
zinc finger and BTB domain containing 16
|
3.21848
|
|
RBMX
|
RNA binding motif protein, X-linked
|
3.20581
|
|
DPH5
|
diphthamide biosynthesis 5
|
3.10955
|
|
NT5E
|
5'-nucleotidase, ecto (CD73)
|
3.10447
|
|
NAP1L1
|
nucleosome assembly protein 1-like 1
|
3.008
|
|
GYPC
|
glycophorin C (Gerbich blood group)
|
3.00751
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PHGDH
|
phosphoglycerate dehydrogenase
|
-4.87619
|
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide
|
-4.80179
|
|
PREB
|
prolactin regulatory element binding
|
-4.3385
|
|
PCDH17
|
protocadherin 17
|
-3.68184
|
|
PELO
|
pelota homolog (Drosophila)
|
-3.4535
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-3.37924
|
|
TXNRD1
|
thioredoxin reductase 1
|
-3.25233
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
-3.16856
|
|
GARS1
|
glycyl-tRNA synthetase 1
|
-3.1637
|
|
PIK3R3
|
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
|
-3.06712
|
