| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/76328936 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in GNE-9605 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C14ORF93 | chromosome 14 open reading frame 93 | 2.93 |
| TPM4 | tropomyosin 4 | 0.59 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.56 |
| DCLRE1B | DNA cross-link repair 1B | 0.49 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.48 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.45 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.43 |
| CMPK2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.38 |
| LIME1 | Lck interacting transmembrane adaptor 1 | 0.37 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 | 0.37 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.36 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.35 |
| SSH2 | slingshot protein phosphatase 2 | 0.35 |
| MYNN | myoneurin | 0.34 |
| ERMARD | ER membrane-associated RNA degradation | 0.34 |
| E2F7 | E2F transcription factor 7 | 0.34 |
| TTC14 | tetratricopeptide repeat domain 14 | 0.34 |
| MSMO1 | methylsterol monooxygenase 1 | 0.33 |
| MADD | MAP-kinase activating death domain | 0.33 |
| MIGA2 | mitoguardin 2 | 0.33 |
| RITA1 | RBPJ interacting and tubulin associated 1 | 0.32 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.32 |
| METTL22 | methyltransferase like 22 | 0.32 |
| HOXB7 | homeobox B7 | 0.32 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.32 |
| C2CD4C | C2 calcium-dependent domain containing 4C | 0.31 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.31 |
| EVI5 | ecotropic viral integration site 5 | 0.31 |
| VIM | vimentin | 0.31 |
| TP73 | tumor protein p73 | 0.31 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | 0.3 |
| MEX3C | mex-3 RNA binding family member C | 0.3 |
| PRSS8 | protease, serine, 8 | 0.3 |
| SMOX | spermine oxidase | 0.29 |
| TTC31 | tetratricopeptide repeat domain 31 | 0.29 |
| OBSL1 | obscurin-like 1 | 0.29 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.28 |
| PLCL2 | phospholipase C-like 2 | 0.27 |
| CRCP | CGRP receptor component | 0.27 |
| CCNQ | cyclin Q | 0.27 |
| NOP10 | NOP10 ribonucleoprotein | 0.27 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.27 |
| DGAT1 | diacylglycerol O-acyltransferase 1 | 0.27 |
| SYTL2 | synaptotagmin-like 2 | 0.26 |
| EYS | eyes shut homolog (Drosophila) | 0.26 |
| APOE | apolipoprotein E | 0.25 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | 0.25 |
| BORA | bora, aurora kinase A activator | 0.25 |
| STK17A | serine/threonine kinase 17a | 0.25 |
| TRIM44 | tripartite motif containing 44 | 0.25 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.25 |
| FUNDC1 | FUN14 domain containing 1 | 0.25 |
| FBH1 | F-box DNA helicase 1 | 0.25 |
| TMEM175 | transmembrane protein 175 | 0.25 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.25 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.24 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.24 |
| ESAM | endothelial cell adhesion molecule | 0.24 |
| SESN1 | sestrin 1 | 0.24 |
| SNX33 | sorting nexin 33 | 0.24 |
| SPIN4 | spindlin family, member 4 | 0.24 |
| NTN1 | netrin 1 | 0.24 |
| FADS1 | fatty acid desaturase 1 | 0.24 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.24 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.23 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.23 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.23 |
| LRIG3 | leucine-rich repeats and immunoglobulin-like domains 3 | 0.23 |
| AOC1 | amine oxidase, copper containing 1 | 0.23 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.22 |
| SAV1 | salvador family WW domain containing protein 1 | 0.22 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | 0.22 |
| PRKX | protein kinase, X-linked | 0.22 |
| LAMB2 | laminin, beta 2 (laminin S) | 0.21 |
| BCL9 | B-cell CLL/lymphoma 9 | 0.21 |
| RPL37A | ribosomal protein L37a | 0.21 |
| BRD7 | bromodomain containing 7 | 0.21 |
| RPS26P11 | ribosomal protein S26 pseudogene 11 | 0.21 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.21 |
| KIAA1522 | KIAA1522 | 0.21 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | 0.21 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.21 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.21 |
| COPRS | coordinator of PRMT5, differentiation stimulator | 0.21 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.21 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.21 |
| CLK1 | CDC-like kinase 1 | 0.21 |
| COMMD9 | COMM domain containing 9 | 0.2 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.2 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.2 |
| NABP1 | nucleic acid binding protein 1 | 0.2 |
| MAP1LC3B2 | microtubule-associated protein 1 light chain 3 beta 2 | 0.2 |
| SQLE | squalene epoxidase | 0.2 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 0.2 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.2 |
| DTNB | dystrobrevin, beta | 0.19 |
| DNAH1 | dynein, axonemal, heavy chain 1 | 0.19 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.19 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 | 0.19 |
| CCDC170 | coiled-coil domain containing 170 | 0.19 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF555 | zinc finger protein 555 | -1.94 |
| ARHGAP44 | Rho GTPase activating protein 44 | -1.46 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | -0.95 |
| AXIN2 | axin 2 | -0.9 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.83 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.79 |
| PIP | prolactin-induced protein | -0.76 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.75 |
| GATD1 | glutamine amidotransferase class 1 domain containing 1 | -0.72 |
| ACTBL2 | actin, beta-like 2 | -0.68 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.63 |
| HEXIM2 | hexamethylene bis-acetamide inducible 2 | -0.57 |
| GAB1 | GRB2-associated binding protein 1 | -0.56 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.55 |
| ZMYM6 | zinc finger, MYM-type 6 | -0.54 |
| BAG4 | BCL2-associated athanogene 4 | -0.5 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | -0.48 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -0.48 |
| METTL25 | methyltransferase like 25 | -0.48 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | -0.47 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | -0.47 |
| ACVR2A | activin A receptor, type IIA | -0.46 |
| BCL10 | B-cell CLL/lymphoma 10 | -0.46 |
| BHLHA15 | basic helix-loop-helix family, member a15 | -0.45 |
| NCOA1 | nuclear receptor coactivator 1 | -0.44 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | -0.44 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.43 |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | -0.43 |
| TIPIN | TIMELESS interacting protein | -0.43 |
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | -0.43 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.42 |
| TIFA | TRAF-interacting protein with forkhead-associated domain | -0.42 |
| SMO | smoothened, frizzled class receptor | -0.41 |
| PHETA1 | PH domain containing endocytic trafficking adaptor 1 | -0.41 |
| ZSWIM9 | zinc finger SWIM-type containing 9 | -0.4 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.4 |
| CERS4 | ceramide synthase 4 | -0.4 |
| NF1 | neurofibromin 1 | -0.4 |
| CNTRL | centriolin | -0.4 |
| YIPF1 | Yip1 domain family, member 1 | -0.38 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | -0.38 |
| KIAA1958 | KIAA1958 | -0.38 |
| H3-3A | H3.3 histone A | -0.38 |
| WTAP | Wilms tumor 1 associated protein | -0.38 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.37 |
| RBL2 | retinoblastoma-like 2 | -0.37 |
| KIAA0232 | KIAA0232 | -0.37 |
| CCDC91 | coiled-coil domain containing 91 | -0.37 |
| RWDD2B | RWD domain containing 2B | -0.37 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.37 |
| PKM | pyruvate kinase, muscle | -0.37 |
| MT1X | metallothionein 1X | -0.36 |
| ZNF175 | zinc finger protein 175 | -0.36 |
| KAZN | kazrin, periplakin interacting protein | -0.36 |
| MVB12B | multivesicular body subunit 12B | -0.35 |
| CCDC158 | coiled-coil domain containing 158 | -0.35 |
| DERPC | DERPC proline and glycine rich nuclear protein | -0.35 |
| ADCY6 | adenylate cyclase 6 | -0.35 |
| FAM160A1 | family with sequence similarity 160, member A1 | -0.34 |
| SPATA7 | spermatogenesis associated 7 | -0.34 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.34 |
| DOCK4 | dedicator of cytokinesis 4 | -0.34 |
| MISP3 | MISP family member 3 | -0.34 |
| ZNF264 | zinc finger protein 264 | -0.34 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.34 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.34 |
| COQ4 | coenzyme Q4 | -0.34 |
| TRIP11 | thyroid hormone receptor interactor 11 | -0.33 |
| PNKD | paroxysmal nonkinesigenic dyskinesia | -0.33 |
| TUFT1 | tuftelin 1 | -0.33 |
| THBS2 | thrombospondin 2 | -0.32 |
| CEP85 | centrosomal protein 85kDa | -0.32 |
| UBAP1 | ubiquitin associated protein 1 | -0.32 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.32 |
| IFI35 | interferon-induced protein 35 | -0.32 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.32 |
| EVI5L | ecotropic viral integration site 5-like | -0.32 |
| GABPB2 | GA binding protein transcription factor, beta subunit 2 | -0.32 |
| MT1F | metallothionein 1F | -0.32 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.32 |
| ZSCAN20 | zinc finger and SCAN domain containing 20 | -0.32 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | -0.32 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | -0.31 |
| BORCS7 | BLOC-1 related complex subunit 7 | -0.31 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.31 |
| CFAP57 | cilia and flagella associated protein 57 | -0.31 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | -0.31 |
| ZNF724 | zinc finger protein 724 | -0.31 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | -0.3 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.3 |
| TMSB10 | thymosin beta 10 | -0.3 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 | -0.3 |
| JUN | jun proto-oncogene | -0.3 |
| CCDC85C | coiled-coil domain containing 85C | -0.3 |
| TMUB1 | transmembrane and ubiquitin-like domain containing 1 | -0.3 |
| METTL7A | methyltransferase like 7A | -0.3 |
| FBXL8 | F-box and leucine-rich repeat protein 8 | -0.3 |
| CLIC6 | chloride intracellular channel 6 | -0.3 |
| ADCY9 | adenylate cyclase 9 | -0.29 |
