GP1BA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description glycoprotein Ib (platelet), alpha polypeptide|Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 2811)
External Link https://ncbi.nlm.nih.gov/gene/2811
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Genes

500 genes differentially expressed following the GP1BA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0122639
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.0111622
AGR2 anterior gradient 2 0.0111006
FST follistatin 0.0104964
OXA1L oxidase (cytochrome c) assembly 1-like 0.0098389
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00966091
TSPAN8 tetraspanin 8 0.00943884
MFAP5 microfibrillar associated protein 5 0.00856395
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00851264
CCNB1 cyclin B1 0.00847891
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00831602
RAI14 retinoic acid induced 14 0.00802273
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00781294
MOXD1 monooxygenase, DBH-like 1 0.00778365
SFRP4 secreted frizzled-related protein 4 0.00773591
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.007553
FBN1 fibrillin 1 0.00754508
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.0074635
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00734851
ADA adenosine deaminase 0.00725265
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00719259
CALD1 caldesmon 1 0.00716102
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00708353
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00707993
KCTD12 potassium channel tetramerization domain containing 12 0.00706428
CHEK1 checkpoint kinase 1 0.00702853
SEPTIN11 septin 11 0.00702768
STK10 serine/threonine kinase 10 0.00701681
PEG3 paternally expressed 3 0.00695359
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00694386
PAWR PRKC, apoptosis, WT1, regulator 0.00681982
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.00680463
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00675247
RNPS1 RNA binding protein S1, serine-rich domain 0.00672263
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00672048
PLS3 plastin 3 0.00668243
COL14A1 collagen, type XIV, alpha 1 0.00667015
SNX7 sorting nexin 7 0.00662693
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00662033
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00660707
AKAP12 A kinase (PRKA) anchor protein 12 0.00659585
COL4A6 collagen, type IV, alpha 6 0.00653733
HEPH hephaestin 0.00653056
HOXB6 homeobox B6 0.00649637
MYO1B myosin IB 0.00649157
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00648583
IFRD2 interferon-related developmental regulator 2 0.00647065
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00640848
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00637147
CLCA1 chloride channel accessory 1 0.00634879
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00633504
WWTR1 WW domain containing transcription regulator 1 0.00633275
REG3A regenerating islet-derived 3 alpha 0.00625063
SRPX sushi-repeat containing protein, X-linked 0.00624554
ACD adrenocortical dysplasia homolog (mouse) 0.00621805
GLS glutaminase 0.00621445
STK39 serine threonine kinase 39 0.00619252
NUSAP1 nucleolar and spindle associated protein 1 0.00615609
DUT deoxyuridine triphosphatase 0.00611764
ENOPH1 enolase-phosphatase 1 0.00611538
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00611078
EDN1 endothelin 1 0.00610258
COL4A5 collagen, type IV, alpha 5 0.00609982
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00609312
PLN phospholamban 0.00606884
DMD dystrophin 0.00605772
PALLD palladin, cytoskeletal associated protein 0.00604735
ITGA6 integrin, alpha 6 0.00604362
NOTCH2NL notch 2 N-terminal like 0.0059735
ASPN asporin 0.00596061
TOX3 TOX high mobility group box family member 3 0.00593044
FERMT1 fermitin family member 1 0.00588365
IL17RB interleukin 17 receptor B 0.0058507
CHGB chromogranin B 0.005849
H2AX H2A.X variant histone 0.00580796
CDC42 cell division cycle 42 0.00579889
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00579758
LAMA4 laminin, alpha 4 0.00579233
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00578804
JAM3 junctional adhesion molecule 3 0.00576479
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00575715
SCG5 secretogranin V 0.0057504
LTBP1 latent transforming growth factor beta binding protein 1 0.00572949
TRIP13 thyroid hormone receptor interactor 13 0.00572548
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 0.00569939
IL1A interleukin 1, alpha 0.00568912
ACOX2 acyl-CoA oxidase 2, branched chain 0.00566464
AKR1C3 aldo-keto reductase family 1, member C3 0.00563919
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00563192
ZNF589 zinc finger protein 589 0.005629
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00560244
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00559934
HMGB2 high mobility group box 2 0.0055507
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00554047
KLHL23 kelch-like family member 23 0.00553489
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00550831
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00550104
GPC3 glypican 3 0.00549404
SGCE sarcoglycan, epsilon 0.00546983
TPD52 tumor protein D52 0.00546875
IPO5 importin 5 0.00546453
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00545984
SI sucrase-isomaltase (alpha-glucosidase) 0.00545687
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00542845
SYNJ2 synaptojanin 2 0.00542738
RAB32 RAB32, member RAS oncogene family 0.00542456
RSL24D1 ribosomal L24 domain containing 1 0.00542431
PDCD6 programmed cell death 6 0.00542334
COL10A1 collagen, type X, alpha 1 0.00541495
HPGDS hematopoietic prostaglandin D synthase 0.00541492
EMX2 empty spiracles homeobox 2 0.00541473
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00541169
CCL19 chemokine (C-C motif) ligand 19 0.0054011
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00538164
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00537947
MYO6 myosin VI 0.00536914
XIC X chromosome inactivation center 0.00533652
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00533415
STK26 serine/threonine protein kinase 26 0.00532156
NAP1L1 nucleosome assembly protein 1-like 1 0.00530323
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00530027
NDP Norrie disease (pseudoglioma) 0.00529836
TRIM2 tripartite motif containing 2 0.00528697
SRSF1 serine/arginine-rich splicing factor 1 0.00525249
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00524848
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00524615
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00522814
HAUS4 HAUS augmin-like complex, subunit 4 0.00521715
MYO5C myosin VC 0.00520523
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00520104
MBL2 mannose-binding lectin (protein C) 2, soluble 0.0051879
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00518718
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00518674
TNC tenascin C 0.00517255
TNIK TRAF2 and NCK interacting kinase 0.0051703
CTSZ cathepsin Z 0.00514492
SPRY2 sprouty homolog 2 (Drosophila) 0.00514414
MEN1 multiple endocrine neoplasia I 0.0051393
FAM169A family with sequence similarity 169, member A 0.00512962
CKS2 CDC28 protein kinase regulatory subunit 2 0.00512948
FLNB filamin B, beta 0.00511643
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00511004
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.00510769
PHACTR2 phosphatase and actin regulator 2 0.00508809
SHTN1 shootin 1 0.00507285
OGN osteoglycin 0.0050717
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00507034
FNBP1 formin binding protein 1 0.00505192
WSB1 WD repeat and SOCS box containing 1 0.00503222
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00501429
SMC1A structural maintenance of chromosomes 1A 0.00501172
SPRED2 sprouty-related, EVH1 domain containing 2 0.00499185
COMP cartilage oligomeric matrix protein 0.00498627
AUTS2 autism susceptibility candidate 2 0.00497669
BAD BCL2-associated agonist of cell death 0.00497639
RCAN2 regulator of calcineurin 2 0.00496573
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00495704
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00494903
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00492979
FCGBP Fc fragment of IgG binding protein 0.00491938
SETX senataxin 0.00490369
MYH11 myosin, heavy chain 11, smooth muscle 0.00490062
SPA17 sperm autoantigenic protein 17 0.00489871
EPCAM epithelial cell adhesion molecule 0.00488151
MEIS2 Meis homeobox 2 0.0048762
CNN1 calponin 1, basic, smooth muscle 0.0048637
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.00486354
RUFY3 RUN and FYVE domain containing 3 0.00485974
HNMT histamine N-methyltransferase 0.00485337
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 0.00484777
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00483782
NRCAM neuronal cell adhesion molecule 0.00483373
TMC5 transmembrane channel-like 5 0.00481779
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00480566
KLK5 kallikrein-related peptidase 5 0.00479897
CBX1 chromobox homolog 1 0.0047884
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00478605
OSR2 odd-skipped related transciption factor 2 0.00477446
MFAP2 microfibrillar-associated protein 2 0.00477145
GMDS GDP-mannose 4,6-dehydratase 0.00476683
SCAMP1 secretory carrier membrane protein 1 0.00476029
TUBB4B tubulin, beta 4B class IVb 0.00475858
PRMT5 protein arginine methyltransferase 5 0.00475547
CPE carboxypeptidase E 0.00474301
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00473089
ITM2A integral membrane protein 2A 0.00471838
COLEC12 collectin sub-family member 12 0.00471266
PRC1 protein regulator of cytokinesis 1 0.00470181
GPX2 glutathione peroxidase 2 0.00467147
PLS1 plastin 1 0.00466282
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.004661
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.00465126
FBN2 fibrillin 2 0.00464293
FAM198B family with sequence similarity 198, member B 0.00463455
SFPQ splicing factor proline/glutamine-rich 0.00462989
NFASC neurofascin 0.00462138
PMP22 peripheral myelin protein 22 0.00461403
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00460881
TRAF3IP2 TRAF3 interacting protein 2 0.0045997
MTCL1 microtubule crosslinking factor 1 0.00458336
SRSF6 serine/arginine-rich splicing factor 6 0.0045786
SPARCL1 SPARC-like 1 (hevin) 0.00457602
MYO1E myosin IE 0.00457418
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00456841
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00456744
CDKN3 cyclin-dependent kinase inhibitor 3 0.00456344
BTNL8 butyrophilin-like 8 0.00456308
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00455934
SAMD4A sterile alpha motif domain containing 4A 0.00454492
ACP6 acid phosphatase 6, lysophosphatidic 0.00452372
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00450021
ELN elastin 0.00449131
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00448711
CDCA4 cell division cycle associated 4 0.00448681
SPON1 spondin 1, extracellular matrix protein 0.00446116
TBC1D12 TBC1 domain family, member 12 0.00445818
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.0044568
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.00445126
GFAP glial fibrillary acidic protein 0.00443722
LGALS4 lectin, galactoside-binding, soluble, 4 0.00443673
DOCK4 dedicator of cytokinesis 4 0.00443193
ADD3 adducin 3 (gamma) 0.00442597
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 0.00442565
ITPK1 inositol-tetrakisphosphate 1-kinase 0.00439779
MFAP4 microfibrillar-associated protein 4 0.00439362
CADM1 cell adhesion molecule 1 0.00439281
OIP5 Opa interacting protein 5 0.00439072
MLXIP MLX interacting protein 0.00438853
HDAC1 histone deacetylase 1 0.00438249
GAL galanin/GMAP prepropeptide 0.0043699
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00435003
FBLN5 fibulin 5 0.00434773
PCLAF PCNA clamp associated factor 0.00433777
SUN1 Sad1 and UNC84 domain containing 1 0.00433753
CEL carboxyl ester lipase 0.00432883
PIAS1 protein inhibitor of activated STAT, 1 0.00432055
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00431274
MZT2A mitotic spindle organizing protein 2A 0.00431081
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00430377
COL21A1 collagen, type XXI, alpha 1 0.00430202
TOX thymocyte selection-associated high mobility group box 0.00429303
ANG angiogenin, ribonuclease, RNase A family, 5 0.00428584
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.00428199
ICA1 islet cell autoantigen 1, 69kDa 0.00427729
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00427616
ZNF207 zinc finger protein 207 0.00427552
CEP55 centrosomal protein 55kDa 0.00427162
C7 complement component 7 0.00427131
PBK PDZ binding kinase 0.00427023
MRPS2 mitochondrial ribosomal protein S2 0.00426907

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.0229538
SLPI secretory leukocyte peptidase inhibitor -0.0165717
SRGN serglycin -0.0159737
AQP3 aquaporin 3 (Gill blood group) -0.0158242
S100A9 S100 calcium binding protein A9 -0.0144603
KRT15 keratin 15, type I -0.0124475
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.0112899
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0112363
JCHAIN joining chain of multimeric IgA and IgM -0.0111192
IFITM1 interferon induced transmembrane protein 1 -0.0106749
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0101313
GNAS GNAS complex locus -0.00998675
BAG3 BCL2-associated athanogene 3 -0.00948476
BST2 bone marrow stromal cell antigen 2 -0.00920268
XPO7 exportin 7 -0.00916695
HLA-B major histocompatibility complex, class I, B -0.00915869
LY6E lymphocyte antigen 6 complex, locus E -0.00882924
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00878568
CFB complement factor B -0.00873766
RNF167 ring finger protein 167 -0.00861666
KRT23 keratin 23, type I -0.00855761
ALOX5 arachidonate 5-lipoxygenase -0.00855208
IFI27 interferon, alpha-inducible protein 27 -0.00853775
HIST1H2AC histone cluster 1, H2ac -0.00844424
THBD thrombomodulin -0.00838654
AQP1 aquaporin 1 (Colton blood group) -0.00820796
TMEM45A transmembrane protein 45A -0.00818808
FABP4 fatty acid binding protein 4, adipocyte -0.00818245
MX1 MX dynamin-like GTPase 1 -0.00816269
LTF lactotransferrin -0.00815006
KRT14 keratin 14, type I -0.0081465
NELL2 NEL-like 2 (chicken) -0.00812826
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00812193
KRT17 keratin 17, type I -0.00811222
MT1X metallothionein 1X -0.00809249
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00806564
KRT13 keratin 13, type I -0.0080017
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00794289
DUSP5 dual specificity phosphatase 5 -0.0078786
IL1RN interleukin 1 receptor antagonist -0.00786347
IFI6 interferon, alpha-inducible protein 6 -0.00781329
CSTA cystatin A (stefin A) -0.00775133
CTSB cathepsin B -0.00770768
KDM5D lysine (K)-specific demethylase 5D -0.00767974
KRT5 keratin 5, type II -0.00761646
ALAS2 5'-aminolevulinate synthase 2 -0.00760666
COCH cochlin -0.00754948
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00744378
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00741064
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00739017
BASP1 brain abundant, membrane attached signal protein 1 -0.00736992
NEU1 sialidase 1 (lysosomal sialidase) -0.0073543
IRF7 interferon regulatory factor 7 -0.00718256
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00717563
WDR26 WD repeat domain 26 -0.00713686
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00707011
IFI16 interferon, gamma-inducible protein 16 -0.00705837
CD9 CD9 molecule -0.00702221
BTG2 BTG family, member 2 -0.00694933
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00693423
TYROBP TYRO protein tyrosine kinase binding protein -0.00692798
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00692404
PRDX2 peroxiredoxin 2 -0.00687344
CLCA2 chloride channel accessory 2 -0.00686783
KLF11 Kruppel-like factor 11 -0.00685792
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00683449
CLIC5 chloride intracellular channel 5 -0.00681607
S100A7 S100 calcium binding protein A7 -0.00675035
SIRT3 sirtuin 3 -0.00672964
LY96 lymphocyte antigen 96 -0.00672805
ECM1 extracellular matrix protein 1 -0.00671196
FGG fibrinogen gamma chain -0.00658032
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00651271
CYBB cytochrome b-245, beta polypeptide -0.00649261
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00644664
TNNT1 troponin T type 1 (skeletal, slow) -0.00644162
CLIC3 chloride intracellular channel 3 -0.00641463
AHSP alpha hemoglobin stabilizing protein -0.0064011
MFSD1 major facilitator superfamily domain containing 1 -0.00638542
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00638159
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.00637067
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00635291
DENND1B DENN/MADD domain containing 1B -0.00633805
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00632006
KLK11 kallikrein-related peptidase 11 -0.00631856
S100A12 S100 calcium binding protein A12 -0.006315
LYZ lysozyme -0.00629527
EMC3 ER membrane protein complex subunit 3 -0.00627454
PF4 platelet factor 4 -0.00621331
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00616729
PDZK1IP1 PDZK1 interacting protein 1 -0.00604864
LBH limb bud and heart development -0.0060398
ARG2 arginase 2 -0.00602975
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00600754
ESR1 estrogen receptor 1 -0.00597517
CRISP3 cysteine-rich secretory protein 3 -0.00596908
LAMP1 lysosomal-associated membrane protein 1 -0.0059582
OXTR oxytocin receptor -0.00594919
EPB42 erythrocyte membrane protein band 4.2 -0.0059476
KRT6A keratin 6A, type II -0.00593123
SCGB2A2 secretoglobin, family 2A, member 2 -0.00592874
CRYAB crystallin, alpha B -0.00591628
GPATCH8 G patch domain containing 8 -0.00589521
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.00589359
RBM38 RNA binding motif protein 38 -0.00589354
OPN3 opsin 3 -0.00586658
TAPBP TAP binding protein (tapasin) -0.0058632
TMEM140 transmembrane protein 140 -0.00584703
TP73-AS1 TP73 antisense RNA 1 -0.00584365
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00583328
LAPTM5 lysosomal protein transmembrane 5 -0.00583317
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00583264
FOSL2 FOS-like antigen 2 -0.00581869
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00581499
ADM adrenomedullin -0.00580525
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00580345
TGM2 transglutaminase 2 -0.00580024
OBSL1 obscurin-like 1 -0.0057978
HCK HCK proto-oncogene, Src family tyrosine kinase -0.00578507
HLA-C major histocompatibility complex, class I, C -0.00576109
CAPG capping protein (actin filament), gelsolin-like -0.00572129
BCL3 B-cell CLL/lymphoma 3 -0.00572086
HMOX1 heme oxygenase 1 -0.00570888
CRABP2 cellular retinoic acid binding protein 2 -0.00570781
PROM1 prominin 1 -0.00570558
ZNF586 zinc finger protein 586 -0.00568856
ACP5 acid phosphatase 5, tartrate resistant -0.00566457
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00565946
NKG7 natural killer cell granule protein 7 -0.00563948
TAL1 T-cell acute lymphocytic leukemia 1 -0.00563301
S100A11 S100 calcium binding protein A11 -0.00562706
C5AR1 complement component 5a receptor 1 -0.00562165
STOM stomatin -0.0055954
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.0055871
S100A2 S100 calcium binding protein A2 -0.00557703
GIMAP4 GTPase, IMAP family member 4 -0.00556684
RTN2 reticulon 2 -0.00553693
STK38 serine/threonine kinase 38 -0.00551977
RCAN1 regulator of calcineurin 1 -0.00550507
PODXL podocalyxin-like -0.00549967
CST7 cystatin F (leukocystatin) -0.00548959
CD53 CD53 molecule -0.00548847
HOXC10 homeobox C10 -0.00548583
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0054818
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00548042
FOXO1 forkhead box O1 -0.00546838
TBC1D31 TBC1 domain family, member 31 -0.00546592
TNS1 tensin 1 -0.00545414
KRT1 keratin 1, type II -0.00541832
PLAAT3 phospholipase A and acyltransferase 3 -0.00541404
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.00541341
TMEM100 transmembrane protein 100 -0.0054119
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00540296
ZNF185 zinc finger protein 185 (LIM domain) -0.00539682
TACSTD2 tumor-associated calcium signal transducer 2 -0.00539057
NPY1R neuropeptide Y receptor Y1 -0.00538804
CTSL cathepsin L -0.00537857
LY6D lymphocyte antigen 6 complex, locus D -0.00537669
SOCS3 suppressor of cytokine signaling 3 -0.00536294
INAVA innate immunity activator -0.00534235
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00533655
TXNDC9 thioredoxin domain containing 9 -0.00529939
DUOX1 dual oxidase 1 -0.00529782
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00529706
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00526727
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00525743
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00524625
IFI44L interferon-induced protein 44-like -0.00523458
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00523059
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00522984
IFI44 interferon-induced protein 44 -0.005219
ENO3 enolase 3 (beta, muscle) -0.00521387
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00520691
SELENBP1 selenium binding protein 1 -0.00519891
DZANK1 double zinc ribbon and ankyrin repeat domains 1 -0.00519643
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00519328
EGR3 early growth response 3 -0.00518819
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00518787
CALML3 calmodulin-like 3 -0.00517805
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00517798
SCEL sciellin -0.00517745
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.0051626
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00515744
TPP1 tripeptidyl peptidase I -0.00515529
ARMCX3 armadillo repeat containing, X-linked 3 -0.00515325
CFD complement factor D (adipsin) -0.00514826
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00514733
GTF2IRD1 GTF2I repeat domain containing 1 -0.00513004
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0051266
CST6 cystatin E/M -0.00512445
GRN granulin -0.00511122
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00509483
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0050923
DAXX death-domain associated protein -0.0050916
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00507815
GBP1 guanylate binding protein 1, interferon-inducible -0.005068
RHCG Rh family, C glycoprotein -0.00505259
NGFR nerve growth factor receptor -0.00502117
TRIP10 thyroid hormone receptor interactor 10 -0.00501271
IGFBP4 insulin-like growth factor binding protein 4 -0.00499955
GLYAT glycine-N-acyltransferase -0.00499136
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00497848
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.00497727
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00497248
DEFB1 defensin, beta 1 -0.00496483
PLBD1 phospholipase B domain containing 1 -0.0049637
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00495941
LAMP3 lysosomal-associated membrane protein 3 -0.00495314
RAI2 retinoic acid induced 2 -0.00493332
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00492863
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.00492592
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00492536
PBX2P1 pre-B-cell leukemia homeobox 2 pseudogene 1 -0.00490338
ARMCX1 armadillo repeat containing, X-linked 1 -0.0048894
PLIN2 perilipin 2 -0.00488019
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00487802
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00487353
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -0.00486108
LAPTM4A lysosomal protein transmembrane 4 alpha -0.0048601
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00484829
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -0.00484227
CLGN calmegin -0.00483968
ADIRF adipogenesis regulatory factor -0.00481786
RGS4 regulator of G-protein signaling 4 -0.00481777
PSAP prosaposin -0.00479894
SIK1 salt-inducible kinase 1 -0.0047826
LY75 lymphocyte antigen 75 -0.00478021
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00476169
LEPROT leptin receptor overlapping transcript -0.00475614
TNNC1 troponin C type 1 (slow) -0.00474939
IL7R interleukin 7 receptor -0.00473437
RPA2 replication protein A2, 32kDa -0.00473426
ZNF419 zinc finger protein 419 -0.00473131
XK X-linked Kx blood group -0.00472481
HBD hemoglobin, delta -0.00468474
EPS8L2 EPS8-like 2 -0.0046843
PLAUR plasminogen activator, urokinase receptor -0.00467802
GBP2 guanylate binding protein 2, interferon-inducible -0.0046724
EPS8L1 EPS8-like 1 -0.00467099
CHD7 chromodomain helicase DNA binding protein 7 -0.00466892
KYNU kynureninase -0.00466295
RAB5B RAB5B, member RAS oncogene family -0.00465565
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00464269
FBXO7 F-box protein 7 -0.00463703
PRKD2 protein kinase D2 -0.00463568
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.0046295
MOSPD1 motile sperm domain containing 1 -0.00461819
STEAP3 STEAP family member 3, metalloreductase -0.00459969
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.00459135
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00458888