GP2D Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

632 gene knockdowns changing fitness of GP2D relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
NELL1 NEL-like 1 (chicken) 3.19303
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 3.19303
GTF2A2 general transcription factor IIA, 2, 12kDa 3.07233
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 2.95698
ARL13B ADP-ribosylation factor-like 13B 2.86533
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2.63902
MMP27 matrix metallopeptidase 27 2.60144
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 2.5871
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 2.5818
NT5C1B-RDH14 NT5C1B-RDH14 readthrough 2.57876
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 2.57722
IL20 interleukin 20 2.56962
KLK1 kallikrein 1 2.56176
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.55134
TMEM234 transmembrane protein 234 2.54824
HSDL1 hydroxysteroid dehydrogenase like 1 2.5159
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 2.46322
COL11A1 collagen, type XI, alpha 1 2.44825
ASPH aspartate beta-hydroxylase 2.40955
G6PC2 glucose-6-phosphatase, catalytic, 2 2.401
ATP10A ATPase, class V, type 10A 2.39954
UBAP1 ubiquitin associated protein 1 2.39477
PIR pirin (iron-binding nuclear protein) 2.37393
FGD5 FYVE, RhoGEF and PH domain containing 5 2.37028
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.35138
CDH20 cadherin 20, type 2 2.33415
WNT2B wingless-type MMTV integration site family, member 2B 2.32367
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2.32322
BBS4 Bardet-Biedl syndrome 4 2.30283
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 2.24663
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.20553
USP10 ubiquitin specific peptidase 10 2.19756
FPGS folylpolyglutamate synthase 2.16245
AGTR1 angiotensin II receptor, type 1 2.15228
PIR-FIGF PIR-FIGF readthrough 2.14552
MS4A7 membrane-spanning 4-domains, subfamily A, member 7 2.12182
RUFY1 RUN and FYVE domain containing 1 2.10133
DGKB diacylglycerol kinase, beta 90kDa 2.09218
RNF112 ring finger protein 112 2.08654
BMP5 bone morphogenetic protein 5 2.08333
DMBT1 deleted in malignant brain tumors 1 2.08016
UBE4B ubiquitination factor E4B 2.07305
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 2.06207
PLAG1 pleiomorphic adenoma gene 1 2.03943
IGF2R insulin-like growth factor 2 receptor 2.03876
ABHD10 abhydrolase domain containing 10 2.02528
MTMR1 myotubularin related protein 1 2.01251
NPTN neuroplastin 2.00907
GPX5 glutathione peroxidase 5 1.97678
TSC22D4 TSC22 domain family, member 4 1.96425
TRPS1 trichorhinophalangeal syndrome I 1.95337
EPHA7 EPH receptor A7 1.95219
OR51T1 olfactory receptor, family 51, subfamily T, member 1 1.94616
TRIP12 thyroid hormone receptor interactor 12 1.91638
HOXB4 homeobox B4 1.90528
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 1.89205
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.89031
NDOR1 NADPH dependent diflavin oxidoreductase 1 1.88
ABR active BCR-related 1.87804
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 1.8439
TRIP11 thyroid hormone receptor interactor 11 1.84213
TRPV2 transient receptor potential cation channel, subfamily V, member 2 1.83356
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.81381
LAMA3 laminin, alpha 3 1.80163
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 1.79648
MAPT microtubule-associated protein tau 1.76822
AQP3 aquaporin 3 (Gill blood group) 1.75003
BTF3 basic transcription factor 3 1.741
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.71868
DUXA double homeobox A 1.71094
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.70537
ZNF253 zinc finger protein 253 1.70374
PTDSS2 phosphatidylserine synthase 2 1.69844
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 1.6868
FGD1 FYVE, RhoGEF and PH domain containing 1 1.68154
LMO1 LIM domain only 1 (rhombotin 1) 1.65741
FBLN1 fibulin 1 1.64637
PEX5 peroxisomal biogenesis factor 5 1.63968
ZFYVE16 zinc finger, FYVE domain containing 16 1.62755
FLNB filamin B, beta 1.61065
THRB thyroid hormone receptor, beta 1.59406
ADSSL1 adenylosuccinate synthase like 1 1.58534
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 1.57528
IFT27 intraflagellar transport 27 1.57454
MBD1 methyl-CpG binding domain protein 1 1.57231
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.56918
ERF Ets2 repressor factor 1.55146
TWIST1 twist family bHLH transcription factor 1 1.53882
H1FX H1 histone family, member X 1.53539
PDHB pyruvate dehydrogenase (lipoamide) beta 1.53318
ZNF569 zinc finger protein 569 1.53265
AKR1D1 aldo-keto reductase family 1, member D1 1.5274
PEG3 paternally expressed 3 1.52699
ATG4B autophagy related 4B, cysteine peptidase 1.52539
ADRB2 adrenoceptor beta 2, surface 1.52174
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.51762
RASD2 RASD family, member 2 1.51534
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 1.51452
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.51037
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.50577
PCDH17 protocadherin 17 1.50308
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.48965
GAL galanin/GMAP prepropeptide 1.48053
SSX6 synovial sarcoma, X breakpoint 6 (pseudogene) 1.47612
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.4674
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 1.46448
SULT4A1 sulfotransferase family 4A, member 1 1.45654
LRMP lymphoid-restricted membrane protein 1.45228
ITGB4 integrin, beta 4 1.44744
GPR151 G protein-coupled receptor 151 1.44099
AMY2A amylase, alpha 2A (pancreatic) 1.43775
PTS 6-pyruvoyltetrahydropterin synthase 1.43559
MAP2K4 mitogen-activated protein kinase kinase 4 1.43292
RPGR retinitis pigmentosa GTPase regulator 1.42818
IKZF4 IKAROS family zinc finger 4 (Eos) 1.41857
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 1.4168
SOCS4 suppressor of cytokine signaling 4 1.41654
RNF146 ring finger protein 146 1.41387
CUL9 cullin 9 1.41337
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.4127
NID1 nidogen 1 1.41235
CTDNEP1 CTD nuclear envelope phosphatase 1 1.40799
KLHL9 kelch-like family member 9 1.40639
PARP12 poly (ADP-ribose) polymerase family, member 12 1.40377
OR2T12 olfactory receptor, family 2, subfamily T, member 12 1.40287
SIX4 SIX homeobox 4 1.4026
DNASE2B deoxyribonuclease II beta 1.40049
SSX7 synovial sarcoma, X breakpoint 7 1.3993
COG3 component of oligomeric golgi complex 3 1.39602
HAND2 heart and neural crest derivatives expressed 2 1.39159
EFNB2 ephrin-B2 1.39082
PTER phosphotriesterase related 1.38138
PKD2L2 polycystic kidney disease 2-like 2 1.37727
FAHD1 fumarylacetoacetate hydrolase domain containing 1 1.37701
LRP6 low density lipoprotein receptor-related protein 6 1.36973
BTF3L4 basic transcription factor 3-like 4 1.3695
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.36316
TNS1 tensin 1 1.36043
SOX10 SRY (sex determining region Y)-box 10 1.35885
MGP matrix Gla protein 1.35535
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 1.34848
ZNF619 zinc finger protein 619 1.34741
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 1.3455
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.34273
PRKY protein kinase, Y-linked, pseudogene 1.34186
TRAF4 TNF receptor-associated factor 4 1.33864
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.33739
BAZ2B bromodomain adjacent to zinc finger domain, 2B 1.33302
COL4A2 collagen, type IV, alpha 2 1.32753
RGS11 regulator of G-protein signaling 11 1.32647
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.32428
CLDN8 claudin 8 1.32118
PREPL prolyl endopeptidase-like 1.32072
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 1.31414
FETUB fetuin B 1.30999
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 1.30526
ETNK1 ethanolamine kinase 1 1.29359
ZNF513 zinc finger protein 513 1.29303
KRT17 keratin 17, type I 1.29192
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.29173
EPC1 enhancer of polycomb homolog 1 (Drosophila) 1.28973
SSX8 synovial sarcoma, X breakpoint 8 1.2882
LBP lipopolysaccharide binding protein 1.2856
ACTC1 actin, alpha, cardiac muscle 1 1.28121
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 1.28033
GPR142 G protein-coupled receptor 142 1.27569
DHH desert hedgehog 1.27507
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 1.27254
API5 apoptosis inhibitor 5 1.26671
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.26321
KYNU kynureninase 1.26218
PYCR2 pyrroline-5-carboxylate reductase family, member 2 1.26069
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 1.25706
R3HDM2 R3H domain containing 2 1.25688
PXK PX domain containing serine/threonine kinase 1.25274
DCLK3 doublecortin-like kinase 3 1.25193
C17ORF85 chromosome 17 open reading frame 85 1.25015
ACTN4 actinin, alpha 4 1.24915
PLD6 phospholipase D family, member 6 1.24248
ZNF329 zinc finger protein 329 1.24082
STX1B syntaxin 1B 1.23943
ALDOC aldolase C, fructose-bisphosphate 1.23596
MC5R melanocortin 5 receptor 1.23158
TAS2R4 taste receptor, type 2, member 4 1.23005
TUBB8 tubulin, beta 8 class VIII 1.22169
PZP pregnancy-zone protein 1.21778
OR6B3 olfactory receptor, family 6, subfamily B, member 3 1.2149
HYOU1 hypoxia up-regulated 1 1.21261
TAS2R14 taste receptor, type 2, member 14 1.20842
CASR calcium-sensing receptor 1.20839
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 1.20575
ZNF57 zinc finger protein 57 1.20551
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 1.20506
ARID4A AT rich interactive domain 4A (RBP1-like) 1.20137
TLR5 toll-like receptor 5 1.19349
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.19292
ZNF600 zinc finger protein 600 1.19046
OXCT1 3-oxoacid CoA transferase 1 1.1878
CCNE2 cyclin E2 1.1835
NUMB numb homolog (Drosophila) 1.18094
IL12A interleukin 12A 1.17985
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 1.1792
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 1.17762
ALAS1 5'-aminolevulinate synthase 1 1.17686
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 1.1762
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1.17536
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2 1.17533
MNT MAX network transcriptional repressor 1.17394
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1 1.17149
ADAM28 ADAM metallopeptidase domain 28 1.17135
ZNF496 zinc finger protein 496 1.16962
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 1.16789
BCOR BCL6 corepressor 1.16723
DPF2 D4, zinc and double PHD fingers family 2 1.16585
SNX1 sorting nexin 1 1.16572
NEK1 NIMA-related kinase 1 1.16379
PCGF6 polycomb group ring finger 6 1.16077
HOXA13 homeobox A13 1.15382
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 1.15381
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 1.15142
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 1.14949
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 1.14866
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.14381
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 1.14284
DLX3 distal-less homeobox 3 1.13342
CCL7 chemokine (C-C motif) ligand 7 1.13116
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.128
ZNF77 zinc finger protein 77 1.12692
PCDHA10 protocadherin alpha 10 1.12662
USP17L1 ubiquitin specific peptidase 17-like family member 1 1.12231
ZNF626 zinc finger protein 626 1.12014
TMEM14A transmembrane protein 14A 1.1199
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 1.11941
RASAL1 RAS protein activator like 1 (GAP1 like) 1.11883
ARSE arylsulfatase E (chondrodysplasia punctata 1) 1.11758
FLT1 fms-related tyrosine kinase 1 1.11348
CEPT1 choline/ethanolamine phosphotransferase 1 1.11226
SERTAD3 SERTA domain containing 3 1.10779
MSL2 male-specific lethal 2 homolog (Drosophila) 1.10261
FNDC3B fibronectin type III domain containing 3B 1.10121
DLAT dihydrolipoamide S-acetyltransferase 1.1012
ELF5 E74-like factor 5 (ets domain transcription factor) 1.0987
CABLES1 Cdk5 and Abl enzyme substrate 1 1.09838
UNKL unkempt family zinc finger-like 1.09807
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 1.09606
SLIT2 slit homolog 2 (Drosophila) 1.09478
HSPA1B heat shock 70kDa protein 1B 1.094
TRIM31 tripartite motif containing 31 1.09347
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.09062
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 1.08792
ADAM17 ADAM metallopeptidase domain 17 1.08616
RBBP7 retinoblastoma binding protein 7 1.08167
DCHS1 dachsous cadherin-related 1 1.08093
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.08015
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.0801
RC3H2 ring finger and CCCH-type domains 2 1.07437
RCN2 reticulocalbin 2, EF-hand calcium binding domain 1.07243
ZNF333 zinc finger protein 333 1.07042
GRK7 G protein-coupled receptor kinase 7 1.07035
GNS glucosamine (N-acetyl)-6-sulfatase 1.06768
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.06724
MAP3K13 mitogen-activated protein kinase kinase kinase 13 1.06622
PRKX protein kinase, X-linked 1.06617
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 1.06343
PCDHGC3 protocadherin gamma subfamily C, 3 1.06003
ZNF117 zinc finger protein 117 1.05365
SARS seryl-tRNA synthetase 1.05046
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 1.04795
MORC3 MORC family CW-type zinc finger 3 1.04792
ADGRL2 adhesion G protein-coupled receptor L2 1.0446
PRDM1 PR domain containing 1, with ZNF domain 1.04294
TECTA tectorin alpha 1.03296
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.03159
NUCB1 nucleobindin 1 1.03111
CLIP1 CAP-GLY domain containing linker protein 1 1.0268
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.02662
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 1.02133
AFF4 AF4/FMR2 family, member 4 1.02076
PEX1 peroxisomal biogenesis factor 1 1.01866
SGOL1 shugoshin-like 1 (S. pombe) 1.01357
ZNF16 zinc finger protein 16 1.0123
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.01093
ADAR adenosine deaminase, RNA-specific 1.01056
ACYP1 acylphosphatase 1, erythrocyte (common) type 1.0082
KRT3 keratin 3, type II 1.00791
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.00727
USP17L3 ubiquitin specific peptidase 17-like family member 3 1.00552
BEGAIN brain-enriched guanylate kinase-associated 1.00339

decreased fitness

Symbol Name Standardized Value
RB1CC1 RB1-inducible coiled-coil 1 -3.00952
SPRY4 sprouty homolog 4 (Drosophila) -2.9459
ARL2-SNX15 ARL2-SNX15 readthrough (NMD candidate) -2.89795
ESRRA estrogen-related receptor alpha -2.82736
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.80193
C10ORF10 chromosome 10 open reading frame 10 -2.72362
PCDHGA2 protocadherin gamma subfamily A, 2 -2.71529
SKA2 spindle and kinetochore associated complex subunit 2 -2.64486
INS-IGF2 INS-IGF2 readthrough -2.6284
HIST3H3 histone cluster 3, H3 -2.61045
ZNF423 zinc finger protein 423 -2.55352
TCF7 transcription factor 7 (T-cell specific, HMG-box) -2.52805
AQR aquarius intron-binding spliceosomal factor -2.44576
RNPS1 RNA binding protein S1, serine-rich domain -2.38698
APC adenomatous polyposis coli -2.37512
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.26206
SNX15 sorting nexin 15 -2.2094
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough -2.20567
TK1 thymidine kinase 1, soluble -2.19699
GRM6 glutamate receptor, metabotropic 6 -2.19162
TARDBP TAR DNA binding protein -2.191
FGF8 fibroblast growth factor 8 (androgen-induced) -2.16533
GFOD2 glucose-fructose oxidoreductase domain containing 2 -2.14517
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.14235
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -2.13672
CCDC71 coiled-coil domain containing 71 -2.13204
SKI SKI proto-oncogene -2.10173
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.09571
ULBP3 UL16 binding protein 3 -2.08359
PRPF38A pre-mRNA processing factor 38A -2.0799
CRP C-reactive protein, pentraxin-related -2.07003
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -2.04164
RP1 retinitis pigmentosa 1 (autosomal dominant) -2.02477
GATA6 GATA binding protein 6 -2.02311
ZFX zinc finger protein, X-linked -2.01487
MEN1 multiple endocrine neoplasia I -2.01184
FFAR2 free fatty acid receptor 2 -2.00397
GTPBP1 GTP binding protein 1 -1.97565
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -1.97336
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 -1.94885
RBM10 RNA binding motif protein 10 -1.94768
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -1.93615
RGS19 regulator of G-protein signaling 19 -1.92955
CCNK cyclin K -1.92911
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 -1.92233
RBM26 RNA binding motif protein 26 -1.8975
EIF4A1 eukaryotic translation initiation factor 4A1 -1.87965
GMIP GEM interacting protein -1.86356
KRAS Kirsten rat sarcoma viral oncogene homolog -1.85903
RPL23AP64 ribosomal protein L23a pseudogene 64 -1.85172
IK IK cytokine, down-regulator of HLA II -1.83948
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 -1.83375
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -1.81397
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -1.81163
MIB2 mindbomb E3 ubiquitin protein ligase 2 -1.80611
RASGEF1C RasGEF domain family, member 1C -1.7991
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) -1.78647
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -1.77471
CALML4 calmodulin-like 4 -1.77449
AP3D1 adaptor-related protein complex 3, delta 1 subunit -1.76431
TWISTNB TWIST neighbor -1.76275
FER fer (fps/fes related) tyrosine kinase -1.75608
MRPL12 mitochondrial ribosomal protein L12 -1.74671
COPE coatomer protein complex, subunit epsilon -1.7429
WEE1 WEE1 G2 checkpoint kinase -1.74247
LRPPRC leucine-rich pentatricopeptide repeat containing -1.73888
CSNK1A1 casein kinase 1, alpha 1 -1.73414
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -1.72185
RPL31 ribosomal protein L31 -1.72123
RPS15A ribosomal protein S15a -1.71916
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -1.71318
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -1.71133
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.7094
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -1.70605
FGF17 fibroblast growth factor 17 -1.68638
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 -1.68534
PDF peptide deformylase (mitochondrial) -1.67622
UBA2 ubiquitin-like modifier activating enzyme 2 -1.67536
HRH2 histamine receptor H2 -1.67529
MAPK4 mitogen-activated protein kinase 4 -1.66971
PAN2 PAN2 poly(A) specific ribonuclease subunit -1.66876
SENP3-EIF4A1 SENP3-EIF4A1 readthrough (NMD candidate) -1.66391
RPS18 ribosomal protein S18 -1.66358
CTCF CCCTC-binding factor (zinc finger protein) -1.66147
SYT15 synaptotagmin XV -1.66065
PRPF4B pre-mRNA processing factor 4B -1.65729
RAB14 RAB14, member RAS oncogene family -1.65379
CTNNBL1 catenin, beta like 1 -1.63706
SYT7 synaptotagmin VII -1.63154
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.62745
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -1.6209
GJB1 gap junction protein, beta 1, 32kDa -1.61785
KCMF1 potassium channel modulatory factor 1 -1.6125
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -1.61235
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -1.61073
BAG6 BCL2-associated athanogene 6 -1.60264
CD36 CD36 molecule (thrombospondin receptor) -1.59864
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -1.59399
TRIM62 tripartite motif containing 62 -1.59307
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -1.59183
ERH enhancer of rudimentary homolog (Drosophila) -1.58662
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 -1.58231
DARS aspartyl-tRNA synthetase -1.57811
RBM8A RNA binding motif protein 8A -1.57433
LIMS1 LIM and senescent cell antigen-like domains 1 -1.5717
ACACA acetyl-CoA carboxylase alpha -1.56952
SRP19 signal recognition particle 19kDa -1.55838
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -1.55629
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -1.55158
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.54921
PLIN3 perilipin 3 -1.5485
CHUK conserved helix-loop-helix ubiquitous kinase -1.54099
IRS2 insulin receptor substrate 2 -1.53579
EIF6 eukaryotic translation initiation factor 6 -1.52655
GPX6 glutathione peroxidase 6 -1.52354
C1RL complement component 1, r subcomponent-like -1.5148
EXO1 exonuclease 1 -1.50319
TPR translocated promoter region, nuclear basket protein -1.50086
MEX3C mex-3 RNA binding family member C -1.50083
HIST1H2BM histone cluster 1, H2bm -1.49851
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.49251
PLA2G3 phospholipase A2, group III -1.48904
AIRE autoimmune regulator -1.48501
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -1.48107
ZNF571 zinc finger protein 571 -1.47867
PRPF6 pre-mRNA processing factor 6 -1.47203
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -1.46536
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 -1.46051
CCL5 chemokine (C-C motif) ligand 5 -1.45817
LHB luteinizing hormone beta polypeptide -1.45467
DNM1L dynamin 1-like -1.45466
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -1.45119
PGD phosphogluconate dehydrogenase -1.4482
ZBTB45 zinc finger and BTB domain containing 45 -1.43842
GALK2 galactokinase 2 -1.43762
ZNF236 zinc finger protein 236 -1.41936
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.41728
RPS6KL1 ribosomal protein S6 kinase-like 1 -1.41697
PPA1 pyrophosphatase (inorganic) 1 -1.41696
MED20 mediator complex subunit 20 -1.41587
ZIK1 zinc finger protein interacting with K protein 1 -1.41055
CECR1 cat eye syndrome chromosome region, candidate 1 -1.40283
GSC goosecoid homeobox -1.40138
DYNLT3 dynein, light chain, Tctex-type 3 -1.39803
PI4KAP2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 -1.38991
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 -1.38881
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.3888
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -1.38334
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.37562
NRL neural retina leucine zipper -1.37159
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -1.37106
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -1.36562
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.35905
RBP5 retinol binding protein 5, cellular -1.35811
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -1.35042
CD8B CD8b molecule -1.35023
NME7 NME/NM23 family member 7 -1.3493
VCP valosin containing protein -1.34864
REG1B regenerating islet-derived 1 beta -1.34601
GH2 growth hormone 2 -1.33958
COPA coatomer protein complex, subunit alpha -1.33493
MED16 mediator complex subunit 16 -1.33489
KHSRP KH-type splicing regulatory protein -1.33051
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -1.32572
CPB1 carboxypeptidase B1 (tissue) -1.32561
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -1.32534
PARP1 poly (ADP-ribose) polymerase 1 -1.3217
C6ORF118 chromosome 6 open reading frame 118 -1.31987
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -1.3182
OIT3 oncoprotein induced transcript 3 -1.31699
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -1.3156
ZFP36L2 ZFP36 ring finger protein-like 2 -1.31519
CXCL6 chemokine (C-X-C motif) ligand 6 -1.31506
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -1.30803
HIST1H2BB histone cluster 1, H2bb -1.3074
TMPRSS11B transmembrane protease, serine 11B -1.30674
RBX1 ring-box 1, E3 ubiquitin protein ligase -1.30434
HNF1B HNF1 homeobox B -1.30408
ECE1 endothelin converting enzyme 1 -1.30376
C17ORF75 chromosome 17 open reading frame 75 -1.30306
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -1.30062
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 -1.29479
ZNF160 zinc finger protein 160 -1.29319
CLCA2 chloride channel accessory 2 -1.28927
NUMA1 nuclear mitotic apparatus protein 1 -1.28376
FOXB1 forkhead box B1 -1.28333
SRRT serrate, RNA effector molecule -1.28216
RAB6B RAB6B, member RAS oncogene family -1.28032
AHCYL1 adenosylhomocysteinase-like 1 -1.27899
CDK2 cyclin-dependent kinase 2 -1.27258
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -1.26948
KIAA0195 KIAA0195 -1.26869
PDIA6 protein disulfide isomerase family A, member 6 -1.26705
CDC5L cell division cycle 5-like -1.26412
SMG6 SMG6 nonsense mediated mRNA decay factor -1.26325
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -1.26315
AJAP1 adherens junctions associated protein 1 -1.26311
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -1.25776
CLCA1 chloride channel accessory 1 -1.25767
KLK11 kallikrein-related peptidase 11 -1.25743
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -1.25523
HNRNPK heterogeneous nuclear ribonucleoprotein K -1.25401
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -1.24901
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -1.24887
PLK3 polo-like kinase 3 -1.24831
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -1.24739
WNT1 wingless-type MMTV integration site family, member 1 -1.2373
GLS glutaminase -1.23685
RPS27A ribosomal protein S27a -1.22798
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -1.22607
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.2239
SGPP2 sphingosine-1-phosphate phosphatase 2 -1.22064
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough -1.21675
MBNL1 muscleblind-like splicing regulator 1 -1.21642
ISY1 ISY1 splicing factor homolog (S. cerevisiae) -1.21505
TM7SF2 transmembrane 7 superfamily member 2 -1.2134
DLD dihydrolipoamide dehydrogenase -1.21138
SAE1 SUMO1 activating enzyme subunit 1 -1.21124
RHD Rh blood group, D antigen -1.20819
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -1.20607
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa -1.2053
ZNF320 zinc finger protein 320 -1.20312
ZNF738 zinc finger protein 738 -1.20278
WDR33 WD repeat domain 33 -1.20209
CSNK2B casein kinase 2, beta polypeptide -1.18385
ZCCHC13 zinc finger, CCHC domain containing 13 -1.18257
KRTAP23-1 keratin associated protein 23-1 -1.17659
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -1.17515
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.17325
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.17303
HRAS Harvey rat sarcoma viral oncogene homolog -1.17217
SLU7 SLU7 splicing factor homolog (S. cerevisiae) -1.17156
IGF2 insulin-like growth factor 2 -1.1687
OR3A1 olfactory receptor, family 3, subfamily A, member 1 -1.1683
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -1.16598
TCF4 transcription factor 4 -1.16305
TRRAP transformation/transcription domain-associated protein -1.1611
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -1.16062
RPS3A ribosomal protein S3A -1.15968
FYN FYN proto-oncogene, Src family tyrosine kinase -1.15955
MT3 metallothionein 3 -1.15448
MEX3B mex-3 RNA binding family member B -1.15344
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.15221
DCTN1 dynactin 1 -1.15103
GSR glutathione reductase -1.15017
RPS17 ribosomal protein S17 -1.14483
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene) -1.14415
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -1.1426
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.14098
ZNF500 zinc finger protein 500 -1.13885
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -1.13761
PHKG2 phosphorylase kinase, gamma 2 (testis) -1.13697
GJA1 gap junction protein, alpha 1, 43kDa -1.13012
CHRM4 cholinergic receptor, muscarinic 4 -1.12522
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.12376
HIST1H2BD histone cluster 1, H2bd -1.12209
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -1.12196
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -1.11948
KPNA3 karyopherin alpha 3 (importin alpha 4) -1.11827
GPR119 G protein-coupled receptor 119 -1.11808
CCNL1 cyclin L1 -1.11314
UGCG UDP-glucose ceramide glucosyltransferase -1.10926
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein -1.10652
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.10603
TRIM49 tripartite motif containing 49 -1.1054
EIF3G eukaryotic translation initiation factor 3, subunit G -1.10353
TMEM189 transmembrane protein 189 -1.10243
IL17C interleukin 17C -1.10114
PHKG1 phosphorylase kinase, gamma 1 (muscle) -1.09983
KIFC1 kinesin family member C1 -1.09937
STON1-GTF2A1L STON1-GTF2A1L readthrough -1.09894
AK3 adenylate kinase 3 -1.09889
CD7 CD7 molecule -1.09605
HSPA8 heat shock 70kDa protein 8 -1.09418
SF3A2 splicing factor 3a, subunit 2, 66kDa -1.091
NPTXR neuronal pentraxin receptor -1.0898
MAP2K6 mitogen-activated protein kinase kinase 6 -1.08937
HIST3H2A histone cluster 3, H2a -1.08885
MAB21L2 mab-21-like 2 (C. elegans) -1.08862
STX4 syntaxin 4 -1.08614
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -1.08524
LIMD1 LIM domains containing 1 -1.08333
DHPS deoxyhypusine synthase -1.08199
SLA2 Src-like-adaptor 2 -1.08115
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta -1.08095
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -1.08071
OLFML2B olfactomedin-like 2B -1.07749
PRDM4 PR domain containing 4 -1.07548
PCDHA8 protocadherin alpha 8 -1.07452
HIST1H3G histone cluster 1, H3g -1.0721
TPO thyroid peroxidase -1.0706
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -1.07048
CLCNKB chloride channel, voltage-sensitive Kb -1.06836
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate) -1.06759
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -1.06746
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.06453
BPTF bromodomain PHD finger transcription factor -1.06269
MED26 mediator complex subunit 26 -1.05782
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.05771
EBNA1BP2 EBNA1 binding protein 2 -1.05672
ZNF211 zinc finger protein 211 -1.05524
AGPS alkylglycerone phosphate synthase -1.05432
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -1.05407
FOXA1 forkhead box A1 -1.05273
PKD2 polycystic kidney disease 2 (autosomal dominant) -1.04972
TRIP13 thyroid hormone receptor interactor 13 -1.04949
GSK3A glycogen synthase kinase 3 alpha -1.04799
SLC10A5 solute carrier family 10, member 5 -1.04154
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -1.04129
YME1L1 YME1-like 1 ATPase -1.04057
ACR acrosin -1.04035
NOTCH1 notch 1 -1.03656
WNT5A wingless-type MMTV integration site family, member 5A -1.03575
L3MBTL2 l(3)mbt-like 2 (Drosophila) -1.03389
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.03356
CD3G CD3g molecule, gamma (CD3-TCR complex) -1.03239
COBL cordon-bleu WH2 repeat protein -1.03084
RPS3 ribosomal protein S3 -1.03048
REPIN1 replication initiator 1 -1.03029
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -1.02968
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.0278
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -1.02758
KRT73 keratin 73, type II -1.02607
ZNF813 zinc finger protein 813 -1.02473
NCAN neurocan -1.02467
SFSWAP splicing factor, suppressor of white-apricot family -1.02284
KCTD8 potassium channel tetramerization domain containing 8 -1.02075
LYRM7 LYR motif containing 7 -1.01903
BAG1 BCL2-associated athanogene -1.01891
SORCS2 sortilin-related VPS10 domain containing receptor 2 -1.01875
CHEK1 checkpoint kinase 1 -1.01872
UBL4B ubiquitin-like 4B -1.01822
RPL5 ribosomal protein L5 -1.0133
WFDC12 WAP four-disulfide core domain 12 -1.01225
ADHFE1 alcohol dehydrogenase, iron containing, 1 -1.01204
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -1.01159
RBM25 RNA binding motif protein 25 -1.01087
WBP11 WW domain binding protein 11 -1.00905
SUMO2 small ubiquitin-like modifier 2 -1.00901
PNPLA8 patatin-like phospholipase domain containing 8 -1.00648
HPGDS hematopoietic prostaglandin D synthase -1.00451
C4BPB complement component 4 binding protein, beta -1.0041
FZD9 frizzled class receptor 9 -1.00058
FAM207A family with sequence similarity 207, member A -1.00041