GPI anchor metabolic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain. (Gene Ontology, GO_0006505)
External Link http://amigo.geneontology.org/amigo/term/GO_0006505
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Genes

28 genes participating in the GPI anchor metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
MPPE1 metallophosphoesterase 1
PGAP1 post-GPI attachment to proteins 1
PGAP2 post-GPI attachment to proteins 2
PGAP3 post-GPI attachment to proteins 3
PGF placental growth factor
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
SLC30A5 solute carrier family 30 (zinc transporter), member 5
TMEM246 transmembrane protein 246
TP53INP2 tumor protein p53 inducible nuclear protein 2