| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | glutathione peroxidase 4|This gene encodes a member of the glutathione peroxidase protein family. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 2879) |
| External Link | https://ncbi.nlm.nih.gov/gene/2879 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the GPX4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0152997 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.0116565 |
| KRT19 | keratin 19, type I | 0.0115437 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0108523 |
| BEX1 | brain expressed, X-linked 1 | 0.0102722 |
| MT1X | metallothionein 1X | 0.00983285 |
| MT1M | metallothionein 1M | 0.00970187 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0092781 |
| MT1F | metallothionein 1F | 0.00926458 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00920442 |
| PCP4 | Purkinje cell protein 4 | 0.00845175 |
| VWF | von Willebrand factor | 0.00838035 |
| MT1E | metallothionein 1E | 0.00821052 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00820268 |
| SDC4 | syndecan 4 | 0.00819845 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00819512 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00800256 |
| PLIN2 | perilipin 2 | 0.00791118 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00786016 |
| ADIRF | adipogenesis regulatory factor | 0.00778908 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00774506 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00773002 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00771905 |
| MAOA | monoamine oxidase A | 0.00765637 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00748808 |
| PROM1 | prominin 1 | 0.00747226 |
| MGP | matrix Gla protein | 0.00738512 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00733307 |
| H1-0 | H1.0 linker histone | 0.00729249 |
| MAOB | monoamine oxidase B | 0.00725419 |
| MAGEA3 | melanoma antigen family A3 | 0.00721129 |
| CHMP4A | charged multivesicular body protein 4A | 0.00712015 |
| TMEM176B | transmembrane protein 176B | 0.00702888 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00697458 |
| MT1H | metallothionein 1H | 0.00695458 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00687652 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0068365 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00682183 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00680604 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00675706 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00674677 |
| NAV2 | neuron navigator 2 | 0.00670202 |
| NRCAM | neuronal cell adhesion molecule | 0.00665985 |
| TNC | tenascin C | 0.00652199 |
| EFNB2 | ephrin-B2 | 0.00651634 |
| GLUL | glutamate-ammonia ligase | 0.00647587 |
| NPTX2 | neuronal pentraxin II | 0.0064105 |
| CLU | clusterin | 0.00629283 |
| KRT8 | keratin 8, type II | 0.00623623 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00611614 |
| GPX3 | glutathione peroxidase 3 | 0.00610495 |
| MGLL | monoglyceride lipase | 0.00609744 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00603417 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00598381 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00597874 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0059764 |
| A2M | alpha-2-macroglobulin | 0.00595469 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.0058807 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00585502 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00585146 |
| JMJD6 | jumonji domain containing 6 | 0.00583522 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00582416 |
| MT1G | metallothionein 1G | 0.00582329 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00581344 |
| G0S2 | G0/G1 switch 2 | 0.00577314 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00576029 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00575923 |
| KRT18 | keratin 18, type I | 0.00568439 |
| PDE8B | phosphodiesterase 8B | 0.00568177 |
| APOD | apolipoprotein D | 0.00565926 |
| MT3 | metallothionein 3 | 0.00564383 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00560372 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00559354 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00558522 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00557171 |
| IL17RB | interleukin 17 receptor B | 0.00556764 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00554423 |
| CLDN5 | claudin 5 | 0.00551918 |
| RGS5 | regulator of G-protein signaling 5 | 0.00542199 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00540301 |
| CCNG2 | cyclin G2 | 0.00539324 |
| CFB | complement factor B | 0.00538318 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00537409 |
| CBX6 | chromobox homolog 6 | 0.00534368 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00534347 |
| AREG | amphiregulin | 0.0053392 |
| RAI2 | retinoic acid induced 2 | 0.00533283 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00532642 |
| PLVAP | plasmalemma vesicle associated protein | 0.00531204 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00530376 |
| AK4 | adenylate kinase 4 | 0.00529896 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00527271 |
| PDE9A | phosphodiesterase 9A | 0.00526648 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00526021 |
| NID1 | nidogen 1 | 0.0052587 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0052571 |
| SYT17 | synaptotagmin XVII | 0.00525087 |
| BRD4 | bromodomain containing 4 | 0.0052468 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0052245 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0052136 |
| ECE1 | endothelin converting enzyme 1 | 0.00518792 |
| TMEM110 | transmembrane protein 110 | 0.00517784 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.0051514 |
| C3 | complement component 3 | 0.00514902 |
| CTSZ | cathepsin Z | 0.00510106 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.00509025 |
| PXDC1 | PX domain containing 1 | 0.00506412 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00505912 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00505739 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00504507 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00503372 |
| ASPH | aspartate beta-hydroxylase | 0.00499186 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00495634 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00495633 |
| RBPMS | RNA binding protein with multiple splicing | 0.00494726 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 | 0.00493342 |
| NMU | neuromedin U | 0.0049267 |
| PLPP3 | phospholipid phosphatase 3 | 0.00492628 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00491986 |
| SEC61G | Sec61 gamma subunit | 0.00490664 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00488992 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.00488637 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00487982 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00487586 |
| ZNF768 | zinc finger protein 768 | 0.00486756 |
| FKBP5 | FK506 binding protein 5 | 0.00485387 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00485059 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00482905 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00481296 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.00481116 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00480569 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.0048011 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00478248 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.004769 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.0047619 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.00474311 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00472693 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00470789 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00469963 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | 0.00469717 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00469031 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00468738 |
| UPP1 | uridine phosphorylase 1 | 0.00467464 |
| ALB | albumin | 0.00465912 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00464794 |
| HHEX | hematopoietically expressed homeobox | 0.00464138 |
| SAFB2 | scaffold attachment factor B2 | 0.00462855 |
| CD38 | CD38 molecule | 0.00462487 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00462382 |
| PMP22 | peripheral myelin protein 22 | 0.00461992 |
| APOB | apolipoprotein B | 0.00461837 |
| HBZ | hemoglobin, zeta | 0.00460314 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00460301 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.0046017 |
| FADS3 | fatty acid desaturase 3 | 0.0046016 |
| SNX10 | sorting nexin 10 | 0.00458068 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00458056 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00456323 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00454786 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00454326 |
| MTF2 | metal response element binding transcription factor 2 | 0.00453842 |
| ADCY9 | adenylate cyclase 9 | 0.00453585 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00451758 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00450129 |
| KRT15 | keratin 15, type I | 0.0045004 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00449395 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00448807 |
| STC1 | stanniocalcin 1 | 0.00448772 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.00448147 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.00447758 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0044677 |
| TBXA2R | thromboxane A2 receptor | 0.00446301 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00445978 |
| CHI3L2 | chitinase 3-like 2 | 0.00445769 |
| TGFA | transforming growth factor, alpha | 0.00445721 |
| WASF1 | WAS protein family, member 1 | 0.00445302 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00444816 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00444514 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00444038 |
| CD200 | CD200 molecule | 0.00442969 |
| TMOD1 | tropomodulin 1 | 0.00442744 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00442728 |
| CPM | carboxypeptidase M | 0.00442179 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00441953 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00441271 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00441167 |
| CHN2 | chimerin 2 | 0.00440851 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00440253 |
| TMSB15A | thymosin beta 15a | 0.00439655 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00438305 |
| BGN | biglycan | 0.00438021 |
| ENG | endoglin | 0.00437213 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00436629 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00436619 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00436362 |
| CFD | complement factor D (adipsin) | 0.00435433 |
| HMOX1 | heme oxygenase 1 | 0.0043363 |
| MUC1 | mucin 1, cell surface associated | 0.00432805 |
| FAM107A | family with sequence similarity 107, member A | 0.00431853 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0043181 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00431624 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0043029 |
| TSPO | translocator protein (18kDa) | 0.00430012 |
| CADM1 | cell adhesion molecule 1 | 0.00429678 |
| TGFB1 | transforming growth factor, beta 1 | 0.00429437 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00428697 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00428091 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00427193 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00427009 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.0042648 |
| TPBG | trophoblast glycoprotein | 0.00424699 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00423031 |
| CBS | cystathionine-beta-synthase | 0.00422811 |
| RND3 | Rho family GTPase 3 | 0.0042265 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00421307 |
| BANP | BTG3 associated nuclear protein | 0.00421212 |
| PLA1A | phospholipase A1 member A | 0.0042063 |
| NUP93 | nucleoporin 93kDa | 0.00420431 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.00418829 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00418595 |
| EREG | epiregulin | 0.00417849 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00417819 |
| STC2 | stanniocalcin 2 | 0.0041729 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00415453 |
| FOLR1 | folate receptor 1 (adult) | 0.00415421 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0041521 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | 0.00415045 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0041475 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00414648 |
| HMG20B | high mobility group 20B | 0.00414425 |
| JAG1 | jagged 1 | 0.00414045 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00413619 |
| PCGF2 | polycomb group ring finger 2 | 0.00413074 |
| EHD2 | EH-domain containing 2 | 0.00412928 |
| SPEN | spen family transcriptional repressor | 0.00412035 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00411635 |
| PCDH17 | protocadherin 17 | 0.00411341 |
| RBM47 | RNA binding motif protein 47 | 0.00411208 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00411099 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00410829 |
| CD320 | CD320 molecule | 0.00409519 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00408504 |
| CAVIN1 | caveolae associated protein 1 | 0.00408433 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 | 0.00408355 |
| CTSB | cathepsin B | 0.00407997 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00407731 |
| BCL2L1 | BCL2-like 1 | 0.00407575 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00407455 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0114129 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00978397 |
| S100A7 | S100 calcium binding protein A7 | -0.00905983 |
| CCN2 | cellular communication network factor 2 | -0.00891002 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00858843 |
| S100A8 | S100 calcium binding protein A8 | -0.0085167 |
| DAPK1 | death-associated protein kinase 1 | -0.00835863 |
| CEL | carboxyl ester lipase | -0.00718771 |
| S100A9 | S100 calcium binding protein A9 | -0.00705678 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00696566 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.00689598 |
| TSPAN8 | tetraspanin 8 | -0.00677505 |
| STK10 | serine/threonine kinase 10 | -0.00667731 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00660994 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00650298 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00643853 |
| CD48 | CD48 molecule | -0.00643144 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00642828 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00627826 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00612327 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00602675 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00601657 |
| SPP1 | secreted phosphoprotein 1 | -0.00586953 |
| CALML5 | calmodulin-like 5 | -0.0058399 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00579938 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0057952 |
| COL5A2 | collagen, type V, alpha 2 | -0.00574366 |
| LTA4H | leukotriene A4 hydrolase | -0.00568258 |
| EPYC | epiphycan | -0.00566643 |
| RGS4 | regulator of G-protein signaling 4 | -0.00561032 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00556728 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00551252 |
| DNM1L | dynamin 1-like | -0.00550598 |
| SPRR1B | small proline-rich protein 1B | -0.00549105 |
| CCNB2 | cyclin B2 | -0.00547478 |
| BTG3 | BTG family, member 3 | -0.0054583 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.00544213 |
| FERMT1 | fermitin family member 1 | -0.00538614 |
| TMEM45A | transmembrane protein 45A | -0.00536366 |
| SRP72 | signal recognition particle 72kDa | -0.00535155 |
| RANBP9 | RAN binding protein 9 | -0.00532693 |
| GAS1 | growth arrest-specific 1 | -0.00532 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00530559 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00529891 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00529495 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00528813 |
| DIPK1A | divergent protein kinase domain 1A | -0.00525565 |
| VASH2 | vasohibin 2 | -0.0052406 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00522781 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00521545 |
| ZNF586 | zinc finger protein 586 | -0.00521157 |
| OPTN | optineurin | -0.00518345 |
| THBS2 | thrombospondin 2 | -0.00517344 |
| KLF10 | Kruppel-like factor 10 | -0.00516965 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00516446 |
| XPO7 | exportin 7 | -0.00514709 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00513342 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00510824 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.00509663 |
| DNTT | DNA nucleotidylexotransferase | -0.00506733 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00506662 |
| PRKCQ | protein kinase C, theta | -0.00499861 |
| DSG1 | desmoglein 1 | -0.00499072 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00498762 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00498593 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00498535 |
| ELOVL4 | ELOVL fatty acid elongase 4 | -0.00497174 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00492957 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00492929 |
| FBN1 | fibrillin 1 | -0.00492078 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00489998 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00489063 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00487613 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.004873 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00487286 |
| CLCA2 | chloride channel accessory 2 | -0.00485307 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00485298 |
| WDR61 | WD repeat domain 61 | -0.00485183 |
| BCHE | butyrylcholinesterase | -0.00482402 |
| TUFT1 | tuftelin 1 | -0.00480965 |
| IL2RG | interleukin 2 receptor, gamma | -0.00479586 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00479049 |
| ITGA6 | integrin, alpha 6 | -0.0047825 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00477518 |
| COL10A1 | collagen, type X, alpha 1 | -0.00475816 |
| TPM2 | tropomyosin 2 (beta) | -0.00474742 |
| ASNSD1 | asparagine synthetase domain containing 1 | -0.00473103 |
| DSG2 | desmoglein 2 | -0.00473017 |
| GAS2 | growth arrest-specific 2 | -0.00472665 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00472459 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00471738 |
| CTSK | cathepsin K | -0.0046777 |
| HOPX | HOP homeobox | -0.00467 |
| NRBF2 | nuclear receptor binding factor 2 | -0.00464828 |
| CD1E | CD1e molecule | -0.00464314 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00464149 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00462829 |
| TFDP1 | transcription factor Dp-1 | -0.00462815 |
| POPDC3 | popeye domain containing 3 | -0.00462781 |
| NELL2 | NEL-like 2 (chicken) | -0.00462737 |
| KLF2 | Kruppel-like factor 2 | -0.00460847 |
| RHOA | ras homolog family member A | -0.00460818 |
| CHEK1 | checkpoint kinase 1 | -0.00459559 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00458323 |
| ATM | ATM serine/threonine kinase | -0.00455617 |
| KLK5 | kallikrein-related peptidase 5 | -0.0045477 |
| PXDN | peroxidasin | -0.00453842 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.00450926 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00450638 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00450515 |
| SMPX | small muscle protein, X-linked | -0.00449841 |
| WT1 | Wilms tumor 1 | -0.00447565 |
| ENSA | endosulfine alpha | -0.004461 |
| FBN2 | fibrillin 2 | -0.00445485 |
| IDE | insulin-degrading enzyme | -0.00444318 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00443927 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00443821 |
| CLTB | clathrin, light chain B | -0.00443494 |
| SEPHS1 | selenophosphate synthetase 1 | -0.0044334 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00443233 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.00443099 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00442151 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.00441451 |
| TRAM1 | translocation associated membrane protein 1 | -0.00439948 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.00438935 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00437645 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00437328 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00436965 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00435699 |
| STK38L | serine/threonine kinase 38 like | -0.00434557 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00433451 |
| LCE2B | late cornified envelope 2B | -0.00433162 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0043267 |
| PCLAF | PCNA clamp associated factor | -0.0043193 |
| GCH1 | GTP cyclohydrolase 1 | -0.00431878 |
| ODAM | odontogenic, ameloblast asssociated | -0.00431137 |
| ADA | adenosine deaminase | -0.0043106 |
| SDC1 | syndecan 1 | -0.00430756 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00429867 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | -0.00429187 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00429121 |
| CCNG1 | cyclin G1 | -0.004288 |
| CD164 | CD164 molecule, sialomucin | -0.00428602 |
| GLCE | glucuronic acid epimerase | -0.0042837 |
| ZNF750 | zinc finger protein 750 | -0.00425322 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00424808 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00424563 |
| CALD1 | caldesmon 1 | -0.00423836 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00421956 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -0.00421901 |
| CAPN3 | calpain 3, (p94) | -0.00420971 |
| LPIN1 | lipin 1 | -0.00419199 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00419134 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00418176 |
| REEP5 | receptor accessory protein 5 | -0.00417293 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.0041615 |
| S100P | S100 calcium binding protein P | -0.00414872 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.0041454 |
| KRT81 | keratin 81, type II | -0.00414219 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00413951 |
| DSC1 | desmocollin 1 | -0.00413545 |
| KIF23 | kinesin family member 23 | -0.00413099 |
| YBX3 | Y box binding protein 3 | -0.00412314 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00411663 |
| MUC4 | mucin 4, cell surface associated | -0.0041113 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00411016 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00410618 |
| SESN1 | sestrin 1 | -0.00410606 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.00410545 |
| EMX2 | empty spiracles homeobox 2 | -0.00409863 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00409365 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00409055 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00409032 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.00408923 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00408523 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00408081 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00408033 |
| BTNL8 | butyrophilin-like 8 | -0.00407305 |
| PRSS23 | protease, serine, 23 | -0.00405913 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00405051 |
| LRRC17 | leucine rich repeat containing 17 | -0.0040481 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00404677 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.00404337 |
| CDC123 | cell division cycle 123 | -0.0040309 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00402165 |
| IVL | involucrin | -0.0040106 |
| NTS | neurotensin | -0.00400311 |
| DUSP2 | dual specificity phosphatase 2 | -0.00399132 |
| PALLD | palladin, cytoskeletal associated protein | -0.0039892 |
| ANXA6 | annexin A6 | -0.0039819 |
| REXO2 | RNA exonuclease 2 | -0.00398085 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00397182 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00396544 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.00396287 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.00395004 |
| LDB2 | LIM domain binding 2 | -0.00393373 |
| PTGES | prostaglandin E synthase | -0.00393369 |
| KRT16 | keratin 16, type I | -0.0039253 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00391723 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | -0.00391592 |
| LGALSL | lectin, galactoside-binding-like | -0.00391136 |
| GNLY | granulysin | -0.0038981 |
| MYO1C | myosin IC | -0.00389655 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00388869 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00388193 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00387633 |
| MCL1 | myeloid cell leukemia 1 | -0.00387385 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.00386909 |
| ABHD4 | abhydrolase domain containing 4 | -0.00386775 |
| GHITM | growth hormone inducible transmembrane protein | -0.00385861 |
| KRT6A | keratin 6A, type II | -0.00384773 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00384728 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00384349 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00383965 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00383703 |
| TCTA | T-cell leukemia translocation altered | -0.00383236 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00383166 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | -0.00382451 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -0.00380963 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00379681 |
| PRRX1 | paired related homeobox 1 | -0.00379097 |
| MTDH | metadherin | -0.00379021 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00377826 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.0037711 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00377075 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.00376987 |
| MATN3 | matrilin 3 | -0.00376956 |
| ZMYND11 | zinc finger, MYND-type containing 11 | -0.00376272 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.00376246 |
| CHPT1 | choline phosphotransferase 1 | -0.00376225 |
| MMP11 | matrix metallopeptidase 11 | -0.00376169 |
| ADD3 | adducin 3 (gamma) | -0.00375746 |
| ARL1 | ADP-ribosylation factor-like 1 | -0.00375264 |
| PLXNC1 | plexin C1 | -0.00374604 |
| ANO10 | anoctamin 10 | -0.00374366 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00374197 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00373993 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00373704 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | -0.00372413 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00372344 |
| USP16 | ubiquitin specific peptidase 16 | -0.00372326 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00372315 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00372308 |
| TM4SF20 | transmembrane 4 L six family member 20 | -0.00372237 |
| YME1L1 | YME1-like 1 ATPase | -0.00371501 |
| VGLL3 | vestigial-like family member 3 | -0.00371241 |
| SNRK | SNF related kinase | -0.00370668 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.00370182 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00368927 |
