GRB10 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description growth factor receptor-bound protein 10|The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 2887)
External Link http://www.ncbi.nlm.nih.gov/gene/2887
Similar Terms
Downloads & Tools

Genes

207 interacting proteins for GRB10 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
ANGPT2 angiopoietin 2
ANKAR ankyrin and armadillo repeat containing
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
ASPH aspartate beta-hydroxylase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BCR breakpoint cluster region
BOLA2 bolA family member 2
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
CAB39 calcium binding protein 39
CALB1 calbindin 1, 28kDa
CALCOCO2 calcium binding and coiled-coil domain 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALU calumenin
CAV1 caveolin 1, caveolae protein, 22kDa
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CEP290 centrosomal protein 290kDa
CKB creatine kinase, brain
CKM creatine kinase, muscle
CKMT1A creatine kinase, mitochondrial 1A
CNTNAP2 contactin associated protein-like 2
CPLX1 complexin 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCD dermcidin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DENND5B DENN/MADD domain containing 5B
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNM1 dynamin 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYSL2 dihydropyrimidinase-like 2
DSG1 desmoglein 1
DSP desmoplakin
DTD1 D-tyrosyl-tRNA deacylase 1
DYNLL1 dynein, light chain, LC8-type 1
ECH1 enoyl CoA hydratase 1, peroxisomal
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EGFR epidermal growth factor receptor
EIF5A eukaryotic translation initiation factor 5A
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
EMD emerin
ENO3 enolase 3 (beta, muscle)
EPHB1 EPH receptor B1
ERC2 ELKS/RAB6-interacting/CAST family member 2
EXOC1 exocyst complex component 1
EXOC4 exocyst complex component 4
FAR1 fatty acyl CoA reductase 1
FBXO2 F-box protein 2
FH fumarate hydratase
FLG2 filaggrin family member 2
FLNA filamin A, alpha
FLNC filamin C, gamma
FSCN1 fascin actin-bundling protein 1
FYCO1 FYVE and coiled-coil domain containing 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GAS8 growth arrest-specific 8
GDI1 GDP dissociation inhibitor 1
GDI2 GDP dissociation inhibitor 2
GEMIN2 gem (nuclear organelle) associated protein 2
GEMIN4 gem (nuclear organelle) associated protein 4
GHR growth hormone receptor
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPC4 glypican 4
GRB2 growth factor receptor-bound protein 2
GSTM1 glutathione S-transferase mu 1
GUK1 guanylate kinase 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBA2 hemoglobin, alpha 2
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HIRIP3 HIRA interacting protein 3
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HRNR hornerin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
IGF1R insulin-like growth factor 1 receptor
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INS insulin
INSR insulin receptor
IQCB1 IQ motif containing B1
IQGAP3 IQ motif containing GTPase activating protein 3
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGA11 integrin, alpha 11
JAK2 Janus kinase 2
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LDHAL6A lactate dehydrogenase A-like 6A
LOX lysyl oxidase
LPCAT2 lysophosphatidylcholine acyltransferase 2
LTN1 listerin E3 ubiquitin protein ligase 1
MAG myelin associated glycoprotein
MAP1B microtubule-associated protein 1B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK1 mitogen-activated protein kinase 1
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MDH1 malate dehydrogenase 1, NAD (soluble)
MEGF10 multiple EGF-like-domains 10
MRPL16 mitochondrial ribosomal protein L16
MSR1 macrophage scavenger receptor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH9 myosin, heavy chain 9, non-muscle
MYO1C myosin IC
NAP1L1 nucleosome assembly protein 1-like 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEFM neurofilament, medium polypeptide
NOA1 nitric oxide associated 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUP188 nucleoporin 188kDa
OXCT1 3-oxoacid CoA transferase 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCP4 Purkinje cell protein 4
PCP4L1 Purkinje cell protein 4 like 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PEA15 phosphoprotein enriched in astrocytes 15
PEBP1 phosphatidylethanolamine binding protein 1
PFDN2 prefoldin subunit 2
PGAM1 phosphoglycerate mutase 1 (brain)
PGD phosphogluconate dehydrogenase
PGK1 phosphoglycerate kinase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDX1 peroxiredoxin 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QDPR quinoid dihydropteridine reductase
RAB14 RAB14, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RET ret proto-oncogene
RNH1 ribonuclease/angiogenin inhibitor 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRBP1 ribosome binding protein 1
SEC16A SEC16 homolog A (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGPL1 sphingosine-1-phosphate lyase 1
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SKP1 S-phase kinase-associated protein 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMN2 survival of motor neuron 2, centromeric
SPATA24 spermatogenesis associated 24
SQRDL sulfide quinone reductase-like (yeast)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STXBP1 syntaxin binding protein 1
SVOPL SVOP-like
SYN2 synapsin II
THBS1 thrombospondin 1
TPI1 triosephosphate isomerase 1
TRIM21 tripartite motif containing 21
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA4A tubulin, alpha 4a
TUBA4B tubulin, alpha 4b
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TWF2 twinfilin actin binding protein 2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE3B ubiquitin protein ligase E3B
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XPOT exportin, tRNA
YBX1 Y box binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZDHHC17 zinc finger, DHHC-type containing 17