GRM Gene Set

Dataset CCLE Cell Line Gene CNV Profiles
Category genomics
Type cell line
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Genes

357 genes with high or low copy number in GRM relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
LOC643486 3.2803
VAV1 vav 1 guanine nucleotide exchange factor 2.59159
RMI1 RecQ mediated genome instability 1 2.5049
C9ORF64 chromosome 9 open reading frame 64 2.5049
HNRNPK heterogeneous nuclear ribonucleoprotein K 2.5049
MIR7-1 microRNA 7-1 2.5049
GKAP1 G kinase anchoring protein 1 2.50442
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.44234
FLJ25758 MAP/microtubule affinity-regulating kinase 1 pseudogene 2.36167
ADGRE4P adhesion G protein-coupled receptor E4, pseudogene 2.36164
MBD3L2 methyl-CpG binding domain protein 3-like 2 2.33741
MBD3L3 methyl-CpG binding domain protein 3-like 3 2.33741
MBD3L4 methyl-CpG binding domain protein 3-like 4 2.33741
MBD3L5 methyl-CpG binding domain protein 3-like 5 2.33741
S1PR3 sphingosine-1-phosphate receptor 3 2.32194
C9ORF47 chromosome 9 open reading frame 47 2.32187
CKS2 CDC28 protein kinase regulatory subunit 2 2.31172
SECISBP2 SECIS binding protein 2 2.31172
MIR3153 microRNA 3153 2.31172
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 2.31153
GADD45G growth arrest and DNA-damage-inducible, gamma 2.31109
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.31107
UNQ6494 uncharacterized LOC100129066 2.31054
AGTPBP1 ATP/GTP binding protein 1 2.30289
MIR4290 microRNA 4290 2.28338
LOC286370 uncharacterized LOC286370 2.28324
LINC01501 long intergenic non-protein coding RNA 1501 2.2831
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.28275
CTSL cathepsin L 2.27665
LOC494127 NFYC pseudogene 2.27655
LOC100506834 uncharacterized LOC100506834 2.27655
C9ORF170 chromosome 9 open reading frame 170 2.27655
GAS1 growth arrest-specific 1 2.27655
CTSL3P cathepsin L family member 3, pseudogene 2.27653
LOC440173 uncharacterized LOC440173 2.27652
MIR4289 microRNA 4289 2.25113
NXNL2 nucleoredoxin-like 2 2.25113
LOC286238 uncharacterized LOC286238 2.25113
SPIN1 spindlin 1 2.25109
ADGRE1 adhesion G protein-coupled receptor E1 2.22923
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.21669
CTSLP8 cathepsin L pseudogene 8 2.21559
LOC392364 nuclear pore associated protein 1 pseudogene 2.21559
SPATA31E1 SPATA31 subfamily E, member 1 2.21559
SNORA84 small nucleolar RNA, H/ACA box 84 2.20182
MIR3651 microRNA 3651 2.20182
CDK20 cyclin-dependent kinase 20 2.20123
SPATA31C2 SPATA31 subfamily C, member 2 2.20123
LINC00475 long intergenic non-protein coding RNA 475 2.20094
LOC100128076 protein tyrosine phosphatase pseudogene 2.2008
IARS isoleucyl-tRNA synthetase 2.19932
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 2.19905
INSR insulin receptor 2.19312
ZNF557 zinc finger protein 557 2.19252
DAPK1 death-associated protein kinase 1 2.18798
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.18599
KIF27 kinesin family member 27 2.15256
NFIL3 nuclear factor, interleukin 3 regulated 2.1513
LOC100129316 uncharacterized LOC100129316 2.15088
AUH AU RNA binding protein/enoyl-CoA hydratase 2.15056
MIR4670 microRNA 4670 2.13401
LOC100128361 uncharacterized LOC100128361 2.13339
BICD2 bicaudal D homolog 2 (Drosophila) 2.13335
ANKRD19P ankyrin repeat domain 19, pseudogene 2.13335
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.13324
MIR3910-2 microRNA 3910-2 2.10293
MIR3910-1 microRNA 3910-1 2.10293
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.10198
LOC389765 kinesin family member 27 pseudogene 2.10122
NOL8 nucleolar protein 8 2.09026
OMD osteomodulin 2.08906
ZNF484 zinc finger protein 484 2.08384
FGD3 FYVE, RhoGEF and PH domain containing 3 2.08367
ROR2 receptor tyrosine kinase-like orphan receptor 2 2.08028
NINJ1 ninjurin 1 2.04489
C9ORF89 chromosome 9 open reading frame 89 2.0446
MIR4291 microRNA 4291 2.04266
OGN osteoglycin 2.04256
SUSD3 sushi domain containing 3 2.04029
BARX1 BARX homeobox 1 2.02751
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.02535
NUTM2F NUT family member 2F 2.0036
ZNF169 zinc finger protein 169 2.00287
PTPDC1 protein tyrosine phosphatase domain containing 1 2.00272
FBP1 fructose-1,6-bisphosphatase 1 1.99076
FBP2 fructose-1,6-bisphosphatase 2 1.99074
ASPN asporin 1.96033
WNK2 WNK lysine deficient protein kinase 2 1.94248
MIRLET7D microRNA let-7d 1.93478
MIRLET7A1 microRNA let-7a-1 1.93478
MIRLET7F1 microRNA let-7f-1 1.93478
MIRLET7DHG MIRLET7D host gene 1.93457
LOC100132077 uncharacterized LOC100132077 1.93098
FAM120AOS family with sequence similarity 120A opposite strand 1.92581
C9ORF129 chromosome 9 open reading frame 129 1.92578
FAM120A family with sequence similarity 120A 1.92544
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 1.8969
C9ORF3 chromosome 9 open reading frame 3 1.88918
LINC00977 long intergenic non-protein coding RNA 977 1.87917
PHF2 PHD finger protein 2 1.86343
HIATL1 hippocampus abundant transcript-like 1 1.85428
C12ORF75 chromosome 12 open reading frame 75 1.80916
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 1.76843
MIR4302 microRNA 4302 1.76471
CENPP centromere protein P 1.70887
LMNTD1 lamin tail domain containing 1 1.6887
RIN2 Ras and Rab interactor 2 1.64676
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 1.64676
C20ORF78 chromosome 20 open reading frame 78 1.64301
SCP2D1 SCP2 sterol-binding domain containing 1 1.64295
LOC100270804 uncharacterized LOC100270804 1.6429
LINC00652 long intergenic non-protein coding RNA 652 1.6429
LOC100130264 uncharacterized LOC100130264 1.63427
SYK spleen tyrosine kinase 1.62333
DZANK1 double zinc ribbon and ankyrin repeat domains 1 1.61644
MIR3192 microRNA 3192 1.61644
LINC00851 long intergenic non-protein coding RNA 851 1.61644
RBBP9 retinoblastoma binding protein 9 1.61607
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 1.61607
SEC23B Sec23 homolog B (S. cerevisiae) 1.61551
LINC00493 long intergenic non-protein coding RNA 493 1.61551
CASC1 cancer susceptibility candidate 1 1.61508
LYRM5 LYR motif containing 5 1.61495
DTD1 D-tyrosyl-tRNA deacylase 1 1.61476
CRNKL1 crooked neck pre-mRNA splicing factor 1 1.61208
OVOL2 ovo-like zinc finger 2 1.60867
MGME1 mitochondrial genome maintenance exonuclease 1 1.60845
CSRP2BP CSRP2 binding protein 1.6081
SNORD17 small nucleolar RNA, C/D box 17 1.60803
SNX5 sorting nexin 5 1.60803
PET117 PET117 homolog (S. cerevisiae) 1.60778
SIRPA signal-regulatory protein alpha 1.60734
PDYN prodynorphin 1.60727
SIRPG signal-regulatory protein gamma 1.60263
LOC100289473 cytoskeleton associated protein 2-like pseudogene 1.60139
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 1.59767
STK35 serine/threonine kinase 35 1.59331
KRAS Kirsten rat sarcoma viral oncogene homolog 1.58436
SNORD119 small nucleolar RNA, C/D box 119 1.57714
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.57714
TGM6 transglutaminase 6 1.57714
BANF2 barrier to autointegration factor 2 1.57692
TGM3 transglutaminase 3 1.57667
LINC01433 long intergenic non-protein coding RNA 1433 1.57306
PRNP prion protein 1.57269
ADRA1D adrenoceptor alpha 1D 1.57259
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1.57096
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.57068
PRND prion protein 2 (dublet) 1.56676
PRNT prion protein (testis specific) 1.56676
CPXM1 carboxypeptidase X (M14 family), member 1 1.56466
TMEM239 transmembrane protein 239 1.56466
C20ORF141 chromosome 20 open reading frame 141 1.56466
PCED1A PC-esterase domain containing 1A 1.56466
EBF4 early B-cell factor 4 1.56446
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 1.56426
PTPRA protein tyrosine phosphatase, receptor type, A 1.56376
FLRT3 fibronectin leucine rich transmembrane protein 3 1.56165
BFSP1 beaded filament structural protein 1, filensin 1.55313
ZNF343 zinc finger protein 343 1.55196
MIR1292 microRNA 1292 1.5519
SNORD110 small nucleolar RNA, C/D box 110 1.5519
SNORD86 small nucleolar RNA, C/D box 86 1.5519
SNORA51 small nucleolar RNA, H/ACA box 51 1.5519
NOP56 NOP56 ribonucleoprotein 1.5519
SNORD57 small nucleolar RNA, C/D box 57 1.5519
SNORD56 small nucleolar RNA, C/D box 56 1.5519
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.55185
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.54911
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 1.54865
TMC2 transmembrane channel-like 2 1.54792
SMOX spermine oxidase 1.54627
MIR103A2 microRNA 103a-2 1.54612
MIR103B2 microRNA 103b-2 1.54612
CDC25B cell division cycle 25B 1.54598
SPEF1 sperm flagellar 1 1.54598
CENPB centromere protein B, 80kDa 1.54598
GFRA4 GDNF family receptor alpha 4 1.54563
ADAM33 ADAM metallopeptidase domain 33 1.54563
ATRN attractin 1.5456
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.54548
KIZ kizuna centrosomal protein 1.543
C20ORF194 chromosome 20 open reading frame 194 1.54277
LZTS3 leucine zipper, putative tumor suppressor family member 3 1.54267
DDRGK1 DDRGK domain containing 1 1.54264
FASTKD5 FAST kinase domains 5 1.54242
AVP arginine vasopressin 1.54235
UBOX5 U-box domain containing 5 1.54235
UBOX5-AS1 UBOX5 antisense RNA 1 1.54235
OXT oxytocin/neurophysin I prepropeptide 1.5423
MRPS26 mitochondrial ribosomal protein S26 1.54221
GNRH2 gonadotropin-releasing hormone 2 1.54221
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 1.54216
TMEM230 transmembrane protein 230 1.54173
PCNA proliferating cell nuclear antigen 1.54173
PCNA-AS1 PCNA antisense RNA 1 1.54173
LOC643406 uncharacterized LOC643406 1.5413
LINC00658 long intergenic non-protein coding RNA 658 1.54123
LINC00654 long intergenic non-protein coding RNA 654 1.54037
DEFB132 defensin, beta 132 1.53743
DEFB129 defensin, beta 129 1.5361
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 1.53477
MAVS mitochondrial antiviral signaling protein 1.53432
TRIB3 tribbles pseudokinase 3 1.53297
SOX12 SRY (sex determining region Y)-box 12 1.53258
ZCCHC3 zinc finger, CCHC domain containing 3 1.5324
DSTN destrin (actin depolymerizing factor) 1.52537
RRBP1 ribosome binding protein 1 1.52513
SIRPD signal-regulatory protein delta 1.52391
DEFB128 defensin, beta 128 1.52241
DEFB126 defensin, beta 126 1.51966
C20ORF27 chromosome 20 open reading frame 27 1.51912
HSPA12B heat shock 70kD protein 12B 1.51876
DEFB127 defensin, beta 127 1.5184
NKX2-4 NK2 homeobox 4 1.51698
PANK2 pantothenate kinase 2 1.5162
PROKR2 prokineticin receptor 2 1.515
RNF24 ring finger protein 24 1.51495
NRSN2 neurensin 2 1.51353
BTBD3 BTB (POZ) domain containing 3 1.5132
TCF15 transcription factor 15 (basic helix-loop-helix) 1.51175
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 1.51164
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.51164
SRXN1 sulfiredoxin 1 1.51146
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1.51024
TBC1D20 TBC1 domain family, member 20 1.51007
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 1.50926
C20ORF202 chromosome 20 open reading frame 202 1.50831
TMEM74B transmembrane protein 74B 1.50795
MIR3616 microRNA 3616 1.50781
BMP2 bone morphogenetic protein 2 1.50701
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.50597
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 1.50511
USP20 ubiquitin specific peptidase 20 1.50509
TMX4 thioredoxin-related transmembrane protein 4 1.5049
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 1.50423
FKBP1A FK506 binding protein 1A, 12kDa 1.5008
FKBP1A-SDCBP2 FKBP1A-SDCBP2 readthrough (NMD candidate) 1.50072
SDCBP2-AS1 SDCBP2 antisense RNA 1 1.50072
SDCBP2 syndecan binding protein (syntenin) 2 1.50072
SNPH syntaphilin 1.50061
NSFL1C NSFL1 (p97) cofactor (p47) 1.50057
INSM1 insulinoma-associated 1 1.50056
SIRPB2 signal-regulatory protein beta 2 1.5
PCSK2 proprotein convertase subtilisin/kexin type 2 1.49989
CHGB chromogranin B 1.49831
TRMT6 tRNA methyltransferase 6 1.49829
LRRN4 leucine rich repeat neuronal 4 1.49829
FERMT1 fermitin family member 1 1.49795
CRLS1 cardiolipin synthase 1 1.4979
MCM8 minichromosome maintenance complex component 8 1.49783
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 1.49504
OTOR otoraplin 1.49485
C20ORF196 chromosome 20 open reading frame 196 1.49445
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.49364
NKX2-2 NK2 homeobox 2 1.49258
XRN2 5'-3' exoribonuclease 2 1.49191
ZNF133 zinc finger protein 133 1.49166
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.49153
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 1.48981
ISM1-AS1 ISM1 antisense RNA 1 1.48872
ISM1 isthmin 1, angiogenesis inhibitor 1.48872
FAM110A family with sequence similarity 110, member A 1.4884
JAG1 jagged 1 1.48827
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 1.48813
ANGPT4 angiopoietin 4 1.48771
MKKS McKusick-Kaufman syndrome 1.47957
SNAP25 synaptosomal-associated protein, 25kDa 1.47957
RAD21L1 RAD21-like 1 (S. pombe) 1.47637
LAMP5 lysosomal-associated membrane protein family, member 5 1.47522
LOC339593 uncharacterized LOC339593 1.47185
PAX1 paired box 1 1.46944
SLX4IP SLX4 interacting protein 1.46665
KIF16B kinesin family member 16B 1.46634
TASP1 taspase, threonine aspartase, 1 1.46556
CST9L cystatin 9-like 1.4646
SCRT2 scratch family zinc finger 2 1.46369
C20ORF96 chromosome 20 open reading frame 96 1.46304
ANKEF1 ankyrin repeat and EF-hand domain containing 1 1.45675
SNAP25-AS1 SNAP25 antisense RNA 1 1.45648
CFAP61 cilia and flagella associated protein 61 1.4557
LINC01432 long intergenic non-protein coding RNA 1432 1.44784
CSTL1 cystatin-like 1 1.44626
CST11 cystatin 11 1.44523
CST13P cystatin 13, pseudogene 1.44313
CST9 cystatin 9 (testatin) 1.44105
CST3 cystatin C 1.44097
CST4 cystatin S 1.43946
RSPO4 R-spondin 4 1.43711
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 1.43135
SSTR4 somatostatin receptor 4 1.42749
THBD thrombomodulin 1.42749
DEFB125 defensin, beta 125 1.42548
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 1.42534
GZF1 GDNF-inducible zinc finger protein 1 1.42534
NXT1 nuclear transport factor 2-like export factor 1 1.42531
LINC00266-1 long intergenic non-protein coding RNA 266-1 1.41625
LINC00656 long intergenic non-protein coding RNA 656 1.41461
CD93 CD93 molecule 1.41081
CST8 cystatin 8 (cystatin-related epididymal specific) 1.40317
LOC100131496 uncharacterized LOC100131496 1.40196
MIR1208 microRNA 1208 1.39188
LOC284788 uncharacterized LOC284788 1.38564
LINC00261 long intergenic non-protein coding RNA 261 1.38559
FOXA2 forkhead box A2 1.38559
LINC00494 long intergenic non-protein coding RNA 494 1.38507
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.36925
SNORD12C small nucleolar RNA, C/D box 12C 1.35473
SNORD12B small nucleolar RNA, C/D box 12B 1.35473
ZFAS1 ZNFX1 antisense RNA 1 1.35473
SNORD12 small nucleolar RNA, C/D box 12 1.35473
ZMYND8 zinc finger, MYND-type containing 8 1.35456
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 1.35453
ZNFX1 zinc finger, NFX1-type containing 1 1.3545
STAU1 staufen double-stranded RNA binding protein 1 1.35433
CELP carboxyl ester lipase pseudogene 1.35301
EYA2 EYA transcriptional coactivator and phosphatase 2 1.34749
NCOA3 nuclear receptor coactivator 3 1.34667
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1.34394
MIR2278 microRNA 2278 1.34004
NTSR1 neurotensin receptor 1 (high affinity) 1.33257

low copy number

Symbol Name Standardized Value
SLC7A14 solute carrier family 7, member 14 -2.85696
CTSLP2 cathepsin L pseudogene 2 -2.50709
PDIA5 protein disulfide isomerase family A, member 5 -2.44079
LINC00343 long intergenic non-protein coding RNA 343 -2.41266
IQCE IQ motif containing E -2.3514
DNAH11 dynein, axonemal, heavy chain 11 -2.35137
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -2.23629
MIR1297 microRNA 1297 -2.11139
LINC00558 long intergenic non-protein coding RNA 558 -2.09655
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit -2.08753
RNU6-64P RNA, U6 small nuclear 64, pseudogene -2.01856
MIR5007 microRNA 5007 -2.00532
CLIC5 chloride intracellular channel 5 -1.98038
CEP128 centrosomal protein 128kDa -1.9708
RNU6-71P RNA, U6 small nuclear 71, pseudogene -1.93046
CADPS Ca++-dependent secretion activator -1.92815
HLA-H major histocompatibility complex, class I, H (pseudogene) -1.84565
MACROD2 MACRO domain containing 2 -1.81161
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 -1.7908
PDLIM5 PDZ and LIM domain 5 -1.78552
AFF2 AF4/FMR2 family, member 2 -1.68717
DGKB diacylglycerol kinase, beta 90kDa -1.6363
OR11H1 olfactory receptor, family 11, subfamily H, member 1 -1.60997
NPAS3 neuronal PAS domain protein 3 -1.58018
ALOX5AP arachidonate 5-lipoxygenase-activating protein -1.57528
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -1.56959
LINC00907 long intergenic non-protein coding RNA 907 -1.53911
VCX3B variable charge, X-linked 3B -1.52364
HCG4B HLA complex group 4B (non-protein coding) -1.50455
WDR7 WD repeat domain 7 -1.50285
ELAC1 elaC ribonuclease Z 1 -1.49818
ERBB2 erb-b2 receptor tyrosine kinase 2 -1.44913
BTG4 B-cell translocation gene 4 -1.44542
MIR548AI microRNA 548ai -1.42894
SMAD4 SMAD family member 4 -1.40134
ARSB arylsulfatase B -1.36194