| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | GSK1059615 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the GSK1059615_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.185764 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.117426 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0746857 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0643819 |
| DST | dystonin | 0.062576 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0615616 |
| SLFN5 | schlafen family member 5 | 0.0603936 |
| SQSTM1 | sequestosome 1 | 0.0598839 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0579805 |
| RND3 | Rho family GTPase 3 | 0.0537086 |
| AUTS2 | autism susceptibility candidate 2 | 0.0524361 |
| CENPF | centromere protein F, 350/400kDa | 0.0521869 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0479999 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0448841 |
| AHNAK | AHNAK nucleoprotein | 0.0443513 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0439461 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0413948 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0410511 |
| SYT1 | synaptotagmin I | 0.0392499 |
| RNF213 | ring finger protein 213 | 0.0388836 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0383173 |
| E2F7 | E2F transcription factor 7 | 0.0367639 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0365301 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0348992 |
| FOXP1 | forkhead box P1 | 0.0347301 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0337082 |
| USP34 | ubiquitin specific peptidase 34 | 0.0334763 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.033466 |
| GOLGB1 | golgin B1 | 0.0333548 |
| MAP1B | microtubule-associated protein 1B | 0.0331358 |
| FNIP1 | folliculin interacting protein 1 | 0.0328366 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0328312 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.032572 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0325246 |
| SKIL | SKI-like proto-oncogene | 0.0323356 |
| NBEAL1 | neurobeachin-like 1 | 0.0314752 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0308282 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0307862 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.03032 |
| JMJD1C | jumonji domain containing 1C | 0.0298995 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.028315 |
| ANK2 | ankyrin 2, neuronal | 0.0282634 |
| TUSC3 | tumor suppressor candidate 3 | 0.027728 |
| APP | amyloid beta (A4) precursor protein | 0.0271193 |
| NPC1 | Niemann-Pick disease, type C1 | 0.026508 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0259941 |
| CCPG1 | cell cycle progression 1 | 0.0252822 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0248079 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0244005 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0239928 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0238926 |
| SUCNR1 | succinate receptor 1 | 0.0238857 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0232477 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0230364 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0229459 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0229067 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0228347 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0227569 |
| CEP112 | centrosomal protein 112kDa | 0.0226933 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0225583 |
| TPR | translocated promoter region, nuclear basket protein | 0.0224533 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0224128 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0223002 |
| CDK13 | cyclin-dependent kinase 13 | 0.0220689 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0217035 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0216784 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0215255 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0211501 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0210484 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0210012 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.020891 |
| CCDC85A | coiled-coil domain containing 85A | 0.0205923 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0205594 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0199863 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | 0.0199585 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.019923 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0199177 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0196964 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0195011 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0194436 |
| CRYM | crystallin, mu | 0.0193517 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0192923 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0188346 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0187853 |
| ZXDC | ZXD family zinc finger C | 0.0187188 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0186628 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0185653 |
| RUNX1 | runt-related transcription factor 1 | 0.0183982 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0182987 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.018202 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0181875 |
| BRD2 | bromodomain containing 2 | 0.0179246 |
| TRABD2B | TraB domain containing 2B | 0.0178865 |
| MED13L | mediator complex subunit 13-like | 0.0177012 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0176829 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0176803 |
| MATR3 | matrin 3 | 0.0176797 |
| EXOC6B | exocyst complex component 6B | 0.0176558 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0174098 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0172721 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.216691 |
| TMSB10 | thymosin beta 10 | -0.200824 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197678 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.106471 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.105577 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101704 |
| VIM | vimentin | -0.0920799 |
| LOX | lysyl oxidase | -0.0888831 |
| PLAT | plasminogen activator, tissue | -0.0740076 |
| NDRG1 | N-myc downstream regulated 1 | -0.0698622 |
| PTMA | prothymosin, alpha | -0.0672896 |
| S100A10 | S100 calcium binding protein A10 | -0.0666093 |
| B2M | beta-2-microglobulin | -0.064381 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0591937 |
| FBN1 | fibrillin 1 | -0.0590312 |
| CD44 | CD44 molecule (Indian blood group) | -0.0577866 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0537383 |
| ANXA2 | annexin A2 | -0.0535059 |
| S100A6 | S100 calcium binding protein A6 | -0.0522255 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0511943 |
| LMNA | lamin A/C | -0.0486289 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0475801 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0461857 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0460056 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0433515 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0430837 |
| LDHA | lactate dehydrogenase A | -0.0430632 |
| STC1 | stanniocalcin 1 | -0.0427073 |
| POTEF | POTE ankyrin domain family, member F | -0.0417234 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0408752 |
| THBS2 | thrombospondin 2 | -0.0408697 |
| HLA-B | major histocompatibility complex, class I, B | -0.0373593 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0368598 |
| MT1X | metallothionein 1X | -0.0368596 |
| CAVIN1 | caveolae associated protein 1 | -0.0354729 |
| MYOF | myoferlin | -0.0353664 |
| MX2 | MX dynamin-like GTPase 2 | -0.0345625 |
| LOXL2 | lysyl oxidase-like 2 | -0.0341527 |
| PKM | pyruvate kinase, muscle | -0.032466 |
| CALR | calreticulin | -0.0318185 |
| SEPTIN9 | septin 9 | -0.03017 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0299113 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0294683 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0294228 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0290523 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0287692 |
| MB21D2 | Mab-21 domain containing 2 | -0.0286372 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0286356 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0282667 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0279222 |
| ACTN4 | actinin, alpha 4 | -0.0277304 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0275514 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.027134 |
| GLIS3 | GLIS family zinc finger 3 | -0.0265792 |
| PFN1 | profilin 1 | -0.0259145 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0257586 |
| RRBP1 | ribosome binding protein 1 | -0.025488 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0253296 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0252185 |
| SEC61G | Sec61 gamma subunit | -0.0250423 |
| HLA-C | major histocompatibility complex, class I, C | -0.0249162 |
| RPS19 | ribosomal protein S19 | -0.0242218 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.024128 |
| FLNB | filamin B, beta | -0.0240402 |
| RPL28 | ribosomal protein L28 | -0.0238066 |
| S100A4 | S100 calcium binding protein A4 | -0.0237322 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0234606 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0233145 |
| GNAS | GNAS complex locus | -0.0227947 |
| RPL36 | ribosomal protein L36 | -0.0227858 |
| CCND1 | cyclin D1 | -0.0226494 |
| TAGLN2 | transgelin 2 | -0.0225689 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0225183 |
| S100A11 | S100 calcium binding protein A11 | -0.0224781 |
| TMSB4X | thymosin beta 4, X-linked | -0.0223965 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0222967 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0222429 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0220873 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0219057 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0215593 |
| COL3A1 | collagen, type III, alpha 1 | -0.0213241 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0208668 |
| PGK1 | phosphoglycerate kinase 1 | -0.0203382 |
| FAM162A | family with sequence similarity 162, member A | -0.0203329 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0202615 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0200962 |
| RPLP2 | ribosomal protein, large, P2 | -0.019922 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0195424 |
| RPS3 | ribosomal protein S3 | -0.0192555 |
| RPL34 | ribosomal protein L34 | -0.0191707 |
| RPL23 | ribosomal protein L23 | -0.0188995 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0188274 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0188133 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.018547 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0182581 |
| RIGI | RNA sensor RIG-I | -0.0181172 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.018087 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0180558 |
| TGFB1 | transforming growth factor, beta 1 | -0.0180385 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0179815 |
