| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | GSK1059615 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the GSK1059615_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.115314 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.067664 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.067099 |
| FTL | ferritin, light polypeptide | 0.0600386 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0565929 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0561491 |
| HLA-B | major histocompatibility complex, class I, B | 0.0549685 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0518449 |
| RPL35A | ribosomal protein L35a | 0.0496637 |
| RPS6 | ribosomal protein S6 | 0.048803 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0406957 |
| RPLP1 | ribosomal protein, large, P1 | 0.0406849 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0404872 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0366254 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0365158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0347623 |
| LMO7 | LIM domain 7 | 0.033264 |
| RPL11 | ribosomal protein L11 | 0.0302048 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0299995 |
| MT2A | metallothionein 2A | 0.0299402 |
| KAZN | kazrin, periplakin interacting protein | 0.0299214 |
| GPC5 | glypican 5 | 0.0292065 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0290962 |
| RPL37 | ribosomal protein L37 | 0.0288782 |
| RPLP0 | ribosomal protein, large, P0 | 0.0280508 |
| RPL34 | ribosomal protein L34 | 0.027227 |
| RPS19 | ribosomal protein S19 | 0.0267775 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0264139 |
| RPL19 | ribosomal protein L19 | 0.0263624 |
| TXNRD1 | thioredoxin reductase 1 | 0.0257554 |
| RPL26 | ribosomal protein L26 | 0.0255386 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0254664 |
| MATR3 | matrin 3 | 0.0253348 |
| RPL23 | ribosomal protein L23 | 0.0252932 |
| RPL12 | ribosomal protein L12 | 0.0252236 |
| RPS8 | ribosomal protein S8 | 0.0251156 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0244557 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0241431 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0240198 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0237137 |
| DSTN | destrin (actin depolymerizing factor) | 0.0236774 |
| HLA-A | major histocompatibility complex, class I, A | 0.0230383 |
| PTMA | prothymosin, alpha | 0.0225809 |
| AHI1 | Abelson helper integration site 1 | 0.0217976 |
| GOLGB1 | golgin B1 | 0.0216818 |
| PHF3 | PHD finger protein 3 | 0.0216003 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0213626 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0213389 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0212265 |
| RPS13 | ribosomal protein S13 | 0.0207299 |
| ATF4 | activating transcription factor 4 | 0.0202604 |
| RPL30 | ribosomal protein L30 | 0.0200685 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0200537 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0197229 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0196723 |
| RPS20 | ribosomal protein S20 | 0.0194613 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0194235 |
| RBM39 | RNA binding motif protein 39 | 0.0193652 |
| RPS23 | ribosomal protein S23 | 0.0193441 |
| MTDH | metadherin | 0.0192195 |
| RPL31 | ribosomal protein L31 | 0.0191383 |
| H3-3B | H3.3 histone B | 0.019056 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0189591 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0188901 |
| RPS24 | ribosomal protein S24 | 0.0188178 |
| RPS27 | ribosomal protein S27 | 0.0186332 |
| RNF149 | ring finger protein 149 | 0.0185776 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0183768 |
| RPL37A | ribosomal protein L37a | 0.0181128 |
| RPL27A | ribosomal protein L27a | 0.0180571 |
| RACK1 | receptor for activated C kinase 1 | 0.0180505 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0178746 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0177908 |
| RPS12 | ribosomal protein S12 | 0.0176744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0174785 |
| CSTB | cystatin B (stefin B) | 0.0173681 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0170341 |
| RPL38 | ribosomal protein L38 | 0.0169176 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0168843 |
| CDCP1 | CUB domain containing protein 1 | 0.0166897 |
| RPS14 | ribosomal protein S14 | 0.0163995 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0163723 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.016329 |
| RPS16 | ribosomal protein S16 | 0.016229 |
| FNBP4 | formin binding protein 4 | 0.0161691 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0160404 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0159685 |
| RPL18 | ribosomal protein L18 | 0.0158556 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0157729 |
| RPS17 | ribosomal protein S17 | 0.0156693 |
| RPS29 | ribosomal protein S29 | 0.0156067 |
| RPL7 | ribosomal protein L7 | 0.0155392 |
| S100P | S100 calcium binding protein P | 0.0153416 |
| RPS28 | ribosomal protein S28 | 0.0152995 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.015282 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.015184 |
| RPL36A | ribosomal protein L36a | 0.0149113 |
| DST | dystonin | 0.0148109 |
| GOLGA2 | golgin A2 | 0.014677 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0145984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.146937 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.131951 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.12935 |
| INTS6 | integrator complex subunit 6 | -0.116688 |
| PRKCA | protein kinase C, alpha | -0.107674 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.103015 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.088783 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0803749 |
| NPSR1 | neuropeptide S receptor 1 | -0.0799757 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0705979 |
| SP100 | SP100 nuclear antigen | -0.0690039 |
| MX1 | MX dynamin-like GTPase 1 | -0.067197 |
| RIGI | RNA sensor RIG-I | -0.066232 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0645187 |
| ANXA2 | annexin A2 | -0.0636751 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0592407 |
| ITGA6 | integrin, alpha 6 | -0.0575858 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0567414 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0555864 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0550816 |
| RAD51B | RAD51 paralog B | -0.0540524 |
| AHNAK | AHNAK nucleoprotein | -0.0538295 |
| VCL | vinculin | -0.0531713 |
| MSI2 | musashi RNA-binding protein 2 | -0.0497755 |
| STK39 | serine threonine kinase 39 | -0.0495718 |
| MX2 | MX dynamin-like GTPase 2 | -0.0495091 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.048483 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0482063 |
| PRELID2 | PRELI domain containing 2 | -0.0474185 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0471406 |
| SMAD3 | SMAD family member 3 | -0.0468546 |
| UBC | ubiquitin C | -0.04671 |
| RUNX1 | runt-related transcription factor 1 | -0.0465078 |
| EPHB2 | EPH receptor B2 | -0.0460365 |
| PLSCR1 | phospholipid scramblase 1 | -0.0459822 |
| EZR | ezrin | -0.0456453 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0446232 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0445057 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0441359 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0435445 |
| SSH2 | slingshot protein phosphatase 2 | -0.0422833 |
| JUN | jun proto-oncogene | -0.041308 |
| ATP11A | ATPase, class VI, type 11A | -0.0399774 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0397471 |
| EFNB2 | ephrin-B2 | -0.0394078 |
| NCKAP5 | NCK-associated protein 5 | -0.039404 |
| AREG | amphiregulin | -0.0393982 |
| RNF213 | ring finger protein 213 | -0.0393006 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0391748 |
| MLPH | melanophilin | -0.038986 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0371897 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0365983 |
| ERBIN | erbb2 interacting protein | -0.0365833 |
| LYZ | lysozyme | -0.036045 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0359609 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0358609 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0355667 |
| SQSTM1 | sequestosome 1 | -0.0355577 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0355361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0351984 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0349986 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0341604 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0332628 |
| ATXN1 | ataxin 1 | -0.0330675 |
| PKM | pyruvate kinase, muscle | -0.0328808 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0327519 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0323726 |
| HDAC4 | histone deacetylase 4 | -0.032169 |
| ASPH | aspartate beta-hydroxylase | -0.0320271 |
| CMIP | c-Maf inducing protein | -0.0318156 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.031813 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0313509 |
| XAF1 | XIAP associated factor 1 | -0.0312381 |
| LAMA4 | laminin, alpha 4 | -0.0311838 |
| POF1B | premature ovarian failure, 1B | -0.0310677 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0310196 |
| MEIS2 | Meis homeobox 2 | -0.0306813 |
| VMP1 | vacuole membrane protein 1 | -0.030509 |
| TRERF1 | transcriptional regulating factor 1 | -0.0301885 |
| TNS4 | tensin 4 | -0.0300042 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0293653 |
| SPATA13 | spermatogenesis associated 13 | -0.0289042 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0286448 |
| MECOM | MDS1 and EVI1 complex locus | -0.0286333 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0285795 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0285615 |
| TBC1D22A | TBC1 domain family, member 22A | -0.028456 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0276611 |
| FAT1 | FAT atypical cadherin 1 | -0.0276241 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0274536 |
| DENND1A | DENN/MADD domain containing 1A | -0.0274254 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0272441 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0269448 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0266783 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0266188 |
| PADI1 | peptidyl arginine deiminase, type I | -0.0265965 |
| DSPP | dentin sialophosphoprotein | -0.0262722 |
| ABLIM1 | actin binding LIM protein 1 | -0.0258217 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0255535 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0247789 |
