| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | GSK1059615 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the GSK1059615_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0818107 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0703865 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0675036 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.0642382 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0629956 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0607173 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0572413 |
| TPR | translocated promoter region, nuclear basket protein | 0.0561988 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0550432 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0526675 |
| MATR3 | matrin 3 | 0.0518611 |
| B2M | beta-2-microglobulin | 0.0513816 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0509728 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0502248 |
| MYO9A | myosin IXA | 0.0501608 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0466428 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0465843 |
| CD44 | CD44 molecule (Indian blood group) | 0.0462986 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.04593 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0458099 |
| OGA | O-GlcNAcase | 0.045412 |
| FN1 | fibronectin 1 | 0.0453949 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0450342 |
| MED13L | mediator complex subunit 13-like | 0.0449029 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0448826 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0439678 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0438361 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0436313 |
| HLA-B | major histocompatibility complex, class I, B | 0.0435584 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0432226 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0421709 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0420506 |
| HLA-A | major histocompatibility complex, class I, A | 0.0418743 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0417923 |
| SLFN5 | schlafen family member 5 | 0.0414372 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0408712 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0407449 |
| CDC73 | cell division cycle 73 | 0.0403919 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0403292 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0401464 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0398144 |
| RORA | RAR-related orphan receptor A | 0.0394574 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0394126 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0389862 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0389281 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0386955 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.038638 |
| LAMC2 | laminin, gamma 2 | 0.0381288 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0381244 |
| USP15 | ubiquitin specific peptidase 15 | 0.0374087 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0365846 |
| PHF3 | PHD finger protein 3 | 0.0361019 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0353746 |
| DTNA | dystrobrevin, alpha | 0.0353395 |
| CALU | calumenin | 0.0349909 |
| WDR70 | WD repeat domain 70 | 0.0346292 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0344416 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0344174 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | 0.0344054 |
| FLNB | filamin B, beta | 0.0343623 |
| FNIP1 | folliculin interacting protein 1 | 0.0343586 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0343003 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0334721 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0331276 |
| MYO1D | myosin ID | 0.0330747 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0327958 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0326137 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0325588 |
| MCL1 | myeloid cell leukemia 1 | 0.0323748 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.032363 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0320522 |
| GLRX | glutaredoxin (thioltransferase) | 0.0319828 |
| NAV1 | neuron navigator 1 | 0.0312742 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0311919 |
| SFTPA2 | surfactant protein A2 | 0.0310848 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0309321 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0308892 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0308589 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0308334 |
| MSN | moesin | 0.0307999 |
| MAP4 | microtubule-associated protein 4 | 0.0304524 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0304031 |
| RSF1 | remodeling and spacing factor 1 | 0.0302816 |
| USP53 | ubiquitin specific peptidase 53 | 0.0301109 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0300061 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0298226 |
| TUFT1 | tuftelin 1 | 0.0297728 |
| SEM1 | SEM1 26S proteasome subunit | 0.0297461 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0296168 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0296098 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0295042 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0294985 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0294761 |
| FAM13A | family with sequence similarity 13, member A | 0.0289643 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0286018 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0284165 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0282507 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0281137 |
| ARMH4 | armadillo like helical domain containing 4 | 0.0278892 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0278678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.171392 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.132485 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.124207 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.107047 |
| MUC16 | mucin 16, cell surface associated | -0.093248 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0880914 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0773066 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0678363 |
| TMSB10 | thymosin beta 10 | -0.0650036 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0623958 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.061815 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0615875 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0615022 |
| LMO7 | LIM domain 7 | -0.0581913 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0575363 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0574379 |
| ANXA2 | annexin A2 | -0.0568589 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0564102 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0563465 |
| KYNU | kynureninase | -0.0562332 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.055479 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0554483 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0547422 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0546703 |
| NPTN | neuroplastin | -0.0545807 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0535518 |
| FTL | ferritin, light polypeptide | -0.0527081 |
| RAB1A | RAB1A, member RAS oncogene family | -0.052147 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0510348 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0489723 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.04886 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0471406 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.04644 |
| NDRG1 | N-myc downstream regulated 1 | -0.04605 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0456252 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0440839 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0436554 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0430328 |
| RIGI | RNA sensor RIG-I | -0.0418546 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0417996 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0403043 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0402908 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0393774 |
| MT2A | metallothionein 2A | -0.0391927 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0381823 |
| LDHA | lactate dehydrogenase A | -0.0367244 |
| RPS16 | ribosomal protein S16 | -0.0358012 |
| ZNF292 | zinc finger protein 292 | -0.0345635 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0342909 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0340934 |
| RPL31 | ribosomal protein L31 | -0.0337006 |
| SQSTM1 | sequestosome 1 | -0.0330209 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0329842 |
| OSMR | oncostatin M receptor | -0.0328627 |
| GOLGA4 | golgin A4 | -0.0326295 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0325837 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0320498 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0318073 |
| INTS6 | integrator complex subunit 6 | -0.0315307 |
| JUP | junction plakoglobin | -0.0312755 |
| MYO1E | myosin IE | -0.0309856 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0307914 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0307054 |
| BCL2L1 | BCL2-like 1 | -0.0305953 |
| PRRC2C | proline-rich coiled-coil 2C | -0.02994 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0293315 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0292488 |
| STEAP4 | STEAP family member 4 | -0.0291742 |
| TAOK3 | TAO kinase 3 | -0.0289189 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0285628 |
| RBM47 | RNA binding motif protein 47 | -0.0285516 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.028222 |
| SLMAP | sarcolemma associated protein | -0.0281506 |
| LAMB3 | laminin, beta 3 | -0.0280926 |
| TJP1 | tight junction protein 1 | -0.027753 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0274349 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0273492 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0272811 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0271291 |
| UBC | ubiquitin C | -0.0270504 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0269784 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0269747 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0269564 |
| MSI2 | musashi RNA-binding protein 2 | -0.02687 |
| CMIP | c-Maf inducing protein | -0.0267914 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0267675 |
| PERP | PERP, TP53 apoptosis effector | -0.0262606 |
| CEP350 | centrosomal protein 350kDa | -0.0262375 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.026023 |
| RREB1 | ras responsive element binding protein 1 | -0.0259729 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0259188 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0259097 |
| NGLY1 | N-glycanase 1 | -0.0258879 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.025829 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.025797 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0257949 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0257888 |
| SPAG9 | sperm associated antigen 9 | -0.0255631 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0255151 |
| RPL9 | ribosomal protein L9 | -0.0252812 |
