| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | GSK1059615 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the GSK1059615_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.14212 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0943819 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0893444 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0739265 |
| HDAC9 | histone deacetylase 9 | 0.0660074 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0579467 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0550577 |
| EGFR | epidermal growth factor receptor | 0.0480585 |
| PCBP2 | poly(rC) binding protein 2 | 0.0432797 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0381622 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0361126 |
| FOXP1 | forkhead box P1 | 0.0329645 |
| EFNA5 | ephrin-A5 | 0.0321871 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0320228 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0283725 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0266373 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0254478 |
| ANXA1 | annexin A1 | 0.024582 |
| RPS2 | ribosomal protein S2 | 0.0240151 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0233961 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0230786 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0230774 |
| GLI3 | GLI family zinc finger 3 | 0.0227682 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0227264 |
| RPL3 | ribosomal protein L3 | 0.0221956 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0214722 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0210097 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0206339 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0202125 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0200346 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.019988 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0197191 |
| VMP1 | vacuole membrane protein 1 | 0.0196124 |
| NBEA | neurobeachin | 0.0195153 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0193185 |
| ZNF438 | zinc finger protein 438 | 0.0185714 |
| BMP10 | bone morphogenetic protein 10 | 0.0185273 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0176019 |
| DUSP4 | dual specificity phosphatase 4 | 0.017518 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0173646 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0173528 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0164929 |
| VEGFA | vascular endothelial growth factor A | 0.016397 |
| FER1L6 | fer-1-like family member 6 | 0.0162722 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0161257 |
| INTS6 | integrator complex subunit 6 | 0.0158793 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0158516 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0158136 |
| PDE7B | phosphodiesterase 7B | 0.0156846 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0156359 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0155939 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0155098 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0154222 |
| MYOF | myoferlin | 0.0153799 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0152242 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0150991 |
| RAB10 | RAB10, member RAS oncogene family | 0.0150023 |
| GSPT1 | G1 to S phase transition 1 | 0.014951 |
| ITGA10 | integrin, alpha 10 | 0.014836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0148308 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0148084 |
| DIAPH3 | diaphanous-related formin 3 | 0.0147871 |
| CUX1 | cut-like homeobox 1 | 0.0147314 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0145138 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0145032 |
| BMP2K | BMP2 inducible kinase | 0.0143563 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | 0.0142988 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0139738 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0137881 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0137266 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0136978 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0136688 |
| MLIP | muscular LMNA-interacting protein | 0.0136643 |
| SEPTIN9 | septin 9 | 0.0136337 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0136025 |
| AEBP2 | AE binding protein 2 | 0.0134161 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0132076 |
| MCPH1 | microcephalin 1 | 0.0131973 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.013027 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0129418 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.012898 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0128803 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0128517 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.012804 |
| XIRP2 | xin actin binding repeat containing 2 | 0.0127954 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0127922 |
| RPS18 | ribosomal protein S18 | 0.0126667 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.012623 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0125999 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0122041 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0121263 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.012077 |
| CDK13 | cyclin-dependent kinase 13 | 0.0120368 |
| GLIS3 | GLIS family zinc finger 3 | 0.0120285 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0119745 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0119613 |
| TRAPPC8 | trafficking protein particle complex 8 | 0.0118049 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0117828 |
| CPNE1 | copine I | 0.0117766 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0116858 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.234931 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.234339 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.203382 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.133444 |
| TMSB4X | thymosin beta 4, X-linked | -0.12866 |
| AHNAK | AHNAK nucleoprotein | -0.0912224 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0833133 |
| S100A6 | S100 calcium binding protein A6 | -0.0824233 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0816477 |
| RPS6 | ribosomal protein S6 | -0.0814296 |
| ACTG1 | actin gamma 1 | -0.0770418 |
| ZNF292 | zinc finger protein 292 | -0.0746634 |
| GOLGA4 | golgin A4 | -0.0668831 |
| RPL35A | ribosomal protein L35a | -0.0656665 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0640132 |
| RBM39 | RNA binding motif protein 39 | -0.0635804 |
| VCL | vinculin | -0.0588695 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.056834 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0555286 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0555036 |
| FLNB | filamin B, beta | -0.0543908 |
| PKM | pyruvate kinase, muscle | -0.0524438 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0501837 |
| RPS19 | ribosomal protein S19 | -0.0501135 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0498502 |
| RPL34 | ribosomal protein L34 | -0.0489957 |
| RPLP1 | ribosomal protein, large, P1 | -0.0486608 |
| RTN4 | reticulon 4 | -0.0477088 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0459373 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.04447 |
| PYGB | phosphorylase, glycogen; brain | -0.0439633 |
| RPS27A | ribosomal protein S27a | -0.0437704 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0423716 |
| RPL12 | ribosomal protein L12 | -0.0412296 |
| RPL13A | ribosomal protein L13a | -0.0410629 |
| GNAS | GNAS complex locus | -0.0404344 |
| PHIP | pleckstrin homology domain interacting protein | -0.0395031 |
| RPL19 | ribosomal protein L19 | -0.0393106 |
| RPLP2 | ribosomal protein, large, P2 | -0.0385937 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0383742 |
| RPS8 | ribosomal protein S8 | -0.0383451 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.038269 |
| RPL32 | ribosomal protein L32 | -0.03806 |
| OGA | O-GlcNAcase | -0.0377205 |
| S100A10 | S100 calcium binding protein A10 | -0.0373837 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0366796 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0365873 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0365126 |
| RPLP0 | ribosomal protein, large, P0 | -0.036372 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0363617 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0362208 |
| FTL | ferritin, light polypeptide | -0.0355767 |
| LDHA | lactate dehydrogenase A | -0.035031 |
| B2M | beta-2-microglobulin | -0.034927 |
| RPS24 | ribosomal protein S24 | -0.0348862 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.033971 |
| PGK1 | phosphoglycerate kinase 1 | -0.0337199 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0330406 |
| HDLBP | high density lipoprotein binding protein | -0.0329858 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.032908 |
| PFN1 | profilin 1 | -0.032891 |
| RRBP1 | ribosome binding protein 1 | -0.0325117 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0323853 |
| COG5 | component of oligomeric golgi complex 5 | -0.0322488 |
| RPL26 | ribosomal protein L26 | -0.0322013 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0321652 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0320883 |
| RPL9 | ribosomal protein L9 | -0.0317655 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.031561 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0314761 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0314603 |
| RPS23 | ribosomal protein S23 | -0.0312766 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0311425 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309689 |
| QKI | QKI, KH domain containing, RNA binding | -0.0309364 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.030727 |
| RPL23 | ribosomal protein L23 | -0.0300739 |
| S100A4 | S100 calcium binding protein A4 | -0.0295855 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0295463 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0290821 |
| FUS | FUS RNA binding protein | -0.0283858 |
| RAB1A | RAB1A, member RAS oncogene family | -0.028145 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0281383 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0279008 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0277932 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.027393 |
| FBXO11 | F-box protein 11 | -0.0272185 |
| RPS25 | ribosomal protein S25 | -0.0271264 |
| LOC112694756 | uncharaterized LOC112694756 | -0.027121 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0270005 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0266328 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0265694 |
| CDC73 | cell division cycle 73 | -0.0264556 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0264395 |
| RPL31 | ribosomal protein L31 | -0.0263735 |
| RBM25 | RNA binding motif protein 25 | -0.0263524 |
| TXNIP | thioredoxin interacting protein | -0.0261915 |
| RNF145 | ring finger protein 145 | -0.0261881 |
| TMSB10 | thymosin beta 10 | -0.0255886 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0252465 |
