| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | GSK1059615 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the GSK1059615_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0698711 |
| SQSTM1 | sequestosome 1 | 0.0545859 |
| SVIL | supervillin | 0.046042 |
| RPL23 | ribosomal protein L23 | 0.0434277 |
| ANXA1 | annexin A1 | 0.0416364 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0414623 |
| RACK1 | receptor for activated C kinase 1 | 0.0392101 |
| ITGAV | integrin, alpha V | 0.0374885 |
| EGR1 | early growth response 1 | 0.0363795 |
| RPS12 | ribosomal protein S12 | 0.035172 |
| RPL37 | ribosomal protein L37 | 0.0350794 |
| RPL35A | ribosomal protein L35a | 0.034382 |
| NTN4 | netrin 4 | 0.0342778 |
| FTL | ferritin, light polypeptide | 0.0338588 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0333048 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0319507 |
| TPI1 | triosephosphate isomerase 1 | 0.031898 |
| RPL18 | ribosomal protein L18 | 0.0311538 |
| RPL37A | ribosomal protein L37a | 0.03104 |
| TOP1 | topoisomerase (DNA) I | 0.0302962 |
| SLFN5 | schlafen family member 5 | 0.0297766 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.0291091 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0286714 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0286098 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0283815 |
| RPLP2 | ribosomal protein, large, P2 | 0.0280849 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0279795 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0278013 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0272863 |
| RPS3 | ribosomal protein S3 | 0.0272141 |
| BPTF | bromodomain PHD finger transcription factor | 0.0271295 |
| SKIL | SKI-like proto-oncogene | 0.0269408 |
| RPL26 | ribosomal protein L26 | 0.0266125 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0265986 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0264213 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0263755 |
| BRD2 | bromodomain containing 2 | 0.0262958 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0260878 |
| UBB | ubiquitin B | 0.0254155 |
| CMYA5 | cardiomyopathy associated 5 | 0.0252579 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0246818 |
| RPS28 | ribosomal protein S28 | 0.0246131 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0241191 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0237158 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0236616 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0234082 |
| UBC | ubiquitin C | 0.0229393 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0228995 |
| RPL27A | ribosomal protein L27a | 0.0228895 |
| RPL9 | ribosomal protein L9 | 0.0226283 |
| TENM2 | teneurin transmembrane protein 2 | 0.0224074 |
| RPL28 | ribosomal protein L28 | 0.0223549 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0220372 |
| RAB31 | RAB31, member RAS oncogene family | 0.0218646 |
| HMGB1 | high mobility group box 1 | 0.0218579 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0218368 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0212176 |
| H2AC6 | H2A clustered histone 6 | 0.0211215 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0210262 |
| BSG | basigin (Ok blood group) | 0.0209065 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0207836 |
| SMAD3 | SMAD family member 3 | 0.0206209 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0205944 |
| RPS14 | ribosomal protein S14 | 0.0204643 |
| IER3 | immediate early response 3 | 0.0204597 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.020414 |
| WWOX | WW domain containing oxidoreductase | 0.0202705 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.02027 |
| AHR | aryl hydrocarbon receptor | 0.0202599 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0202265 |
| ANXA2 | annexin A2 | 0.0199799 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0199587 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0195224 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0194999 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0194776 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0194735 |
| RPLP1 | ribosomal protein, large, P1 | 0.0194457 |
| JUN | jun proto-oncogene | 0.0194429 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0192056 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0189948 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0189754 |
| DUSP12 | dual specificity phosphatase 12 | 0.0188761 |
| JMJD1C | jumonji domain containing 1C | 0.0188691 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0188069 |
| ZC3H18 | zinc finger CCCH-type containing 18 | 0.0187212 |
| POLN | polymerase (DNA directed) nu | 0.0186594 |
| TMSB4X | thymosin beta 4, X-linked | 0.0184549 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0183891 |
| B2M | beta-2-microglobulin | 0.0183577 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.0182904 |
| RPL12 | ribosomal protein L12 | 0.018168 |
| RPS8 | ribosomal protein S8 | 0.0181674 |
| RPS27 | ribosomal protein S27 | 0.0181313 |
| EXOC6B | exocyst complex component 6B | 0.0177832 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0177517 |
| PERP | PERP, TP53 apoptosis effector | 0.0177505 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0177303 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0175912 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 | 0.0175819 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0175678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155012 |
| SMYD3 | SET and MYND domain containing 3 | -0.152257 |
| CD44 | CD44 molecule (Indian blood group) | -0.109128 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104885 |
| VIM | vimentin | -0.0881024 |
| GOLGA4 | golgin A4 | -0.0873001 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0819059 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0782772 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0752397 |
| ATM | ATM serine/threonine kinase | -0.0733576 |
| PRELID2 | PRELI domain containing 2 | -0.0728873 |
| HMGA2 | high mobility group AT-hook 2 | -0.0727955 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0714076 |
| ASPH | aspartate beta-hydroxylase | -0.0713439 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0692813 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0682594 |
| SDC4 | syndecan 4 | -0.0657963 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0656788 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0611748 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0593045 |
| AHNAK | AHNAK nucleoprotein | -0.0580412 |
| ATXN1 | ataxin 1 | -0.0579321 |
| SNX14 | sorting nexin 14 | -0.057909 |
| ZNF292 | zinc finger protein 292 | -0.056718 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0563143 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0555942 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0539266 |
| CALU | calumenin | -0.0528594 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0526491 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0522297 |
| NGLY1 | N-glycanase 1 | -0.0517196 |
| TPX2 | TPX2, microtubule-associated | -0.0508997 |
| NDRG1 | N-myc downstream regulated 1 | -0.0506881 |
| CENPF | centromere protein F, 350/400kDa | -0.0494586 |
| TMEM123 | transmembrane protein 123 | -0.0493236 |
| OSMR | oncostatin M receptor | -0.0493129 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0492933 |
| YAP1 | Yes-associated protein 1 | -0.048754 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0482988 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0474756 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0474017 |
| ARFGEF3 | ARFGEF family member 3 | -0.0473712 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0465099 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0462856 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.045826 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0451621 |
| YBX3 | Y box binding protein 3 | -0.0447966 |
| NF1 | neurofibromin 1 | -0.0443645 |
| FLNB | filamin B, beta | -0.0438074 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0436914 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0428677 |
| ANLN | anillin, actin binding protein | -0.0427275 |
| SPAG9 | sperm associated antigen 9 | -0.0426114 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0418219 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0417834 |
| DTNA | dystrobrevin, alpha | -0.0415247 |
| PYGL | phosphorylase, glycogen, liver | -0.0411446 |
| NAV2 | neuron navigator 2 | -0.0410132 |
| PGK1 | phosphoglycerate kinase 1 | -0.0405266 |
| DST | dystonin | -0.0402685 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0401971 |
| ACTG1 | actin gamma 1 | -0.0401658 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0394367 |
| GPC6 | glypican 6 | -0.0393612 |
| RRBP1 | ribosome binding protein 1 | -0.0391232 |
| KIAA1328 | KIAA1328 | -0.0378724 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0369749 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0366595 |
| PTMA | prothymosin, alpha | -0.0365889 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0362107 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0357519 |
| DNER | delta/notch-like EGF repeat containing | -0.0356971 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.035274 |
| VCL | vinculin | -0.035164 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0346869 |
| PODXL | podocalyxin-like | -0.0345583 |
| RAI14 | retinoic acid induced 14 | -0.0344771 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0340354 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0339257 |
| PRKCE | protein kinase C, epsilon | -0.0338809 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.033166 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0326627 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0326585 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0325204 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0319846 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0319246 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0319162 |
| LMNA | lamin A/C | -0.0318405 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0316619 |
| FMN1 | formin 1 | -0.0312546 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0312362 |
| MYO9B | myosin IXB | -0.0310491 |
| ATG7 | autophagy related 7 | -0.0309533 |
| KIF4A | kinesin family member 4A | -0.0300587 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0300264 |
| PUM2 | pumilio RNA-binding family member 2 | -0.029822 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0297887 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0294521 |
| CPNE1 | copine I | -0.0293049 |
| MKI67 | marker of proliferation Ki-67 | -0.0292426 |
