| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | glycogen synthase kinase 3 beta|The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 2932) |
| External Link | https://ncbi.nlm.nih.gov/gene/2932 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the GSK3B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.0207517 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0146784 |
| HMOX1 | heme oxygenase 1 | 0.0108653 |
| GAB2 | GRB2-associated binding protein 2 | 0.0106108 |
| PCNA | proliferating cell nuclear antigen | 0.0102123 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0100963 |
| HOPX | HOP homeobox | 0.0096513 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00962141 |
| BAG2 | BCL2-associated athanogene 2 | 0.00960156 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00955415 |
| TCTA | T-cell leukemia translocation altered | 0.00951359 |
| XIC | X chromosome inactivation center | 0.00931447 |
| DSE | dermatan sulfate epimerase | 0.00922317 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00875868 |
| JMJD6 | jumonji domain containing 6 | 0.00873058 |
| PTK2 | protein tyrosine kinase 2 | 0.00865576 |
| TUBA4A | tubulin, alpha 4a | 0.00861845 |
| GOLT1B | golgi transport 1B | 0.00848893 |
| MIR22HG | MIR22 host gene | 0.0084255 |
| TCF4 | transcription factor 4 | 0.00829337 |
| IL1R2 | interleukin 1 receptor, type II | 0.00819193 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00812781 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00806409 |
| SPP1 | secreted phosphoprotein 1 | 0.0080541 |
| TMEM45A | transmembrane protein 45A | 0.00802683 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00800225 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0079977 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 0.00778627 |
| TASOR2 | transcription activation suppressor family member 2 | 0.00777719 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.0076538 |
| CHN1 | chimerin 1 | 0.00764049 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00753656 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00739718 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.00735802 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00727281 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00726503 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00720918 |
| H1-2 | H1.2 linker histone, cluster member | 0.00717756 |
| GOLM1 | golgi membrane protein 1 | 0.00716391 |
| ABHD3 | abhydrolase domain containing 3 | 0.00712471 |
| CCN3 | cellular communication network factor 3 | 0.00709525 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0070598 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00701024 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | 0.00698218 |
| DDA1 | DET1 and DDB1 associated 1 | 0.00697788 |
| ADIPOR2 | adiponectin receptor 2 | 0.00695898 |
| TMEM70 | transmembrane protein 70 | 0.00695424 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00692978 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00688653 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00688597 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00688201 |
| BRD4 | bromodomain containing 4 | 0.00687046 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00685134 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00684519 |
| MTX2 | metaxin 2 | 0.00684124 |
| SPRR2B | small proline-rich protein 2B | 0.00683956 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00676747 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00676275 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00674652 |
| RGCC | regulator of cell cycle | 0.00672888 |
| CHMP5 | charged multivesicular body protein 5 | 0.00672857 |
| PCDH17 | protocadherin 17 | 0.00670991 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00670386 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00668601 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.0066852 |
| CCNC | cyclin C | 0.00666186 |
| SPRR1B | small proline-rich protein 1B | 0.00661549 |
| PFN2 | profilin 2 | 0.0066046 |
| CLTB | clathrin, light chain B | 0.00658164 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00654313 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00654241 |
| TFRC | transferrin receptor | 0.00653405 |
| KRT6A | keratin 6A, type II | 0.00649752 |
| RGS13 | regulator of G-protein signaling 13 | 0.00645364 |
| PDGFD | platelet derived growth factor D | 0.00643834 |
| RRAGD | Ras-related GTP binding D | 0.00643725 |
| KRT16 | keratin 16, type I | 0.00640294 |
| DSG1 | desmoglein 1 | 0.00636009 |
| RGS5 | regulator of G-protein signaling 5 | 0.00635974 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00634264 |
| NIT1 | nitrilase 1 | 0.00630716 |
| PRPF3 | pre-mRNA processing factor 3 | 0.00629724 |
| PKP2 | plakophilin 2 | 0.00629448 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00629434 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00629332 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00628622 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00627238 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00626043 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.00625713 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0062435 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00621355 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00620902 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00620351 |
| ADM | adrenomedullin | 0.00620146 |
| MAGEA3 | melanoma antigen family A3 | 0.00618663 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00617665 |
| ZNRD2 | zinc ribbon domain containing 2 | 0.00613923 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.0061341 |
| LY96 | lymphocyte antigen 96 | 0.00612504 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.0061221 |
| CLU | clusterin | 0.0060948 |
| ZNF395 | zinc finger protein 395 | 0.00608764 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00608222 |
| S100A2 | S100 calcium binding protein A2 | 0.00606922 |
| SST | somatostatin | 0.00606053 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00606033 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00605551 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00605151 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00604258 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00604167 |
| GRPEL1 | GrpE-like 1, mitochondrial (E. coli) | 0.00604035 |
| BMP2 | bone morphogenetic protein 2 | 0.00603478 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.00599852 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00599591 |
| LYRM2 | LYR motif containing 2 | 0.00598696 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0059864 |
| PERP | PERP, TP53 apoptosis effector | 0.00598543 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00598252 |
| PELO | pelota homolog (Drosophila) | 0.0059805 |
| YBX3 | Y box binding protein 3 | 0.00598001 |
| MAEA | macrophage erythroblast attacher | 0.00594242 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00594038 |
| CA12 | carbonic anhydrase XII | 0.00590293 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0058827 |
| TMEM176B | transmembrane protein 176B | 0.00587691 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00586119 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00584813 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00581695 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0058168 |
| TCP1 | t-complex 1 | 0.00580923 |
| PLS3 | plastin 3 | 0.00580663 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.00578454 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00578035 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00576123 |
| TMEM126B | transmembrane protein 126B | 0.00575802 |
| HLX | H2.0-like homeobox | 0.00575373 |
| KRT6B | keratin 6B, type II | 0.0057523 |
| KLK5 | kallikrein-related peptidase 5 | 0.00574672 |
| PRSS23 | protease, serine, 23 | 0.00574407 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00574257 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | 0.00573225 |
| DPP8 | dipeptidyl-peptidase 8 | 0.0057199 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00570562 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00569653 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.00568186 |
| SPRR1A | small proline-rich protein 1A | 0.00568089 |
| YIPF6 | Yip1 domain family, member 6 | 0.00565256 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00565083 |
| CST6 | cystatin E/M | 0.00563428 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00563184 |
| SNX13 | sorting nexin 13 | 0.00562889 |
| FOXD1 | forkhead box D1 | 0.00560943 |
| EXOSC4 | exosome component 4 | 0.00559651 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00559497 |
| RBM47 | RNA binding motif protein 47 | 0.00559382 |
| MOB4 | MOB family member 4, phocein | 0.00558888 |
| TYMS | thymidylate synthetase | 0.00556729 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00555896 |
| KRT1 | keratin 1, type II | 0.00555494 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00552384 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00550729 |
| RAB38 | RAB38, member RAS oncogene family | 0.00550345 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.00549744 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 0.00549729 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00549636 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00545634 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | 0.00545347 |
| STK26 | serine/threonine protein kinase 26 | 0.00544913 |
| RRAGA | Ras-related GTP binding A | 0.00544387 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00543063 |
| CPD | carboxypeptidase D | 0.00542765 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | 0.00542566 |
| CYC1 | cytochrome c-1 | 0.00541766 |
| MPC1 | mitochondrial pyruvate carrier 1 | 0.00539627 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00538643 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00537747 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | 0.00535047 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.00534427 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00532295 |
| MAGEA4 | melanoma antigen family A4 | 0.00531952 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00531104 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.00530562 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00530289 |
| SNX7 | sorting nexin 7 | 0.00529266 |
| ELOC | elongin C | 0.00528399 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00527174 |
| IL32 | interleukin 32 | 0.00526969 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00525425 |
| PHB | prohibitin | 0.00524855 |
| KRT14 | keratin 14, type I | 0.0052352 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00523133 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00522577 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00522419 |
| MOSPD1 | motile sperm domain containing 1 | 0.00522353 |
| LOR | loricrin | 0.0052215 |
| PANX1 | pannexin 1 | 0.00521858 |
| GAS6 | growth arrest-specific 6 | 0.00521662 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.00521422 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00519245 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00518666 |
| TCF12 | transcription factor 12 | 0.00516127 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00514183 |
| CFH | complement factor H | 0.0051402 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00513804 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00510907 |
| PDCD10 | programmed cell death 10 | 0.005093 |
| GLA | galactosidase, alpha | 0.00508597 |
| TAGLN2 | transgelin 2 | 0.00508218 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00508097 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00505474 |
| BTG3 | BTG family, member 3 | 0.00504659 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00504514 |
| KLK7 | kallikrein-related peptidase 7 | 0.00503901 |
| CXORF40B | chromosome X open reading frame 40B | 0.00503503 |
| MRPS12 | mitochondrial ribosomal protein S12 | 0.00502075 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.00501003 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00500888 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00500257 |
| CLDND1 | claudin domain containing 1 | 0.00500051 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0049992 |
| KRT17 | keratin 17, type I | 0.00499794 |
| IFNGR1 | interferon gamma receptor 1 | 0.00499504 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.00498571 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00497579 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00496628 |
| RNF115 | ring finger protein 115 | 0.00496368 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00495945 |
| MT1M | metallothionein 1M | 0.0049399 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00493947 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00493652 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00493636 |
| CERS2 | ceramide synthase 2 | 0.00493303 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00492846 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00491937 |
| MED17 | mediator complex subunit 17 | 0.00491924 |
| CXORF40A | chromosome X open reading frame 40A | 0.00491717 |
| GLRX2 | glutaredoxin 2 | 0.00491487 |
| GCG | glucagon | 0.0049109 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00490175 |
| TRIB3 | tribbles pseudokinase 3 | 0.00490068 |
| NCK1 | NCK adaptor protein 1 | 0.0048999 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00489654 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00489466 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00488931 |
| ZNF281 | zinc finger protein 281 | 0.00488188 |
| SPAG9 | sperm associated antigen 9 | 0.00487213 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0048709 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00485807 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00484518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0125735 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0121522 |
| MMP7 | matrix metallopeptidase 7 | -0.0121121 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0112287 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0108302 |
| COG7 | component of oligomeric golgi complex 7 | -0.010565 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0101825 |
| TFF1 | trefoil factor 1 | -0.00998224 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00985808 |
| ADD3 | adducin 3 (gamma) | -0.00965921 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00962134 |
| KRT19 | keratin 19, type I | -0.00948272 |
| TAPBP | TAP binding protein (tapasin) | -0.00930309 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00927254 |
| SRGN | serglycin | -0.00908753 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00884728 |
| PCP4 | Purkinje cell protein 4 | -0.0087206 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00868484 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00868405 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.0086742 |
| ZW10 | zw10 kinetochore protein | -0.00860796 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00858044 |
| KRT7 | keratin 7, type II | -0.00855638 |
| COLEC12 | collectin sub-family member 12 | -0.00852852 |
| LMNB1 | lamin B1 | -0.0085277 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00846883 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00839774 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00834226 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00830636 |
| FHL1 | four and a half LIM domains 1 | -0.00826297 |
| MLPH | melanophilin | -0.00824332 |
| OLFM1 | olfactomedin 1 | -0.00822788 |
| GNAS | GNAS complex locus | -0.00822243 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00818202 |
| MGP | matrix Gla protein | -0.00809391 |
| EPCAM | epithelial cell adhesion molecule | -0.00809152 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00808859 |
| THBS1 | thrombospondin 1 | -0.00808616 |
| NAV2 | neuron navigator 2 | -0.00806941 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00806585 |
| LXN | latexin | -0.00802417 |
| SYNM | synemin, intermediate filament protein | -0.00800714 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00797226 |
| OLFM4 | olfactomedin 4 | -0.0079531 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00786743 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00775639 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00765551 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00765084 |
| MAL | mal, T-cell differentiation protein | -0.00765047 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00764998 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00761128 |
| RNF144A | ring finger protein 144A | -0.00756799 |
| ATP9A | ATPase, class II, type 9A | -0.00756446 |
| IL2RG | interleukin 2 receptor, gamma | -0.00752214 |
| GUSB | glucuronidase, beta | -0.0074946 |
| SVIL | supervillin | -0.00746605 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00745365 |
| CHRDL1 | chordin-like 1 | -0.00742913 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00742579 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00740741 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00735925 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00728926 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00728137 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00724962 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00719499 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00715904 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0071554 |
| TXNIP | thioredoxin interacting protein | -0.00712585 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00708223 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00706512 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00705138 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.00700045 |
| PRKCA | protein kinase C, alpha | -0.00695873 |
| NID2 | nidogen 2 (osteonidogen) | -0.00691905 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00690528 |
| A2M | alpha-2-macroglobulin | -0.00688112 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00688064 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00687543 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00687291 |
| LEPR | leptin receptor | -0.00685647 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00682333 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00681613 |
| TRIB2 | tribbles pseudokinase 2 | -0.00680731 |
| CLDN3 | claudin 3 | -0.00679676 |
| TADA2A | transcriptional adaptor 2A | -0.00676319 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00675613 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00674994 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -0.00674818 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00672136 |
| ERP29 | endoplasmic reticulum protein 29 | -0.00670123 |
| PLAT | plasminogen activator, tissue | -0.0066951 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00669324 |
| VCAN | versican | -0.00668467 |
| NELL2 | NEL-like 2 (chicken) | -0.00668088 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00665542 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.00665342 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.0066434 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00660145 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -0.0065862 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00658376 |
| STK38 | serine/threonine kinase 38 | -0.00655306 |
| STON1 | stonin 1 | -0.00654852 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00654032 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00652718 |
| KLK3 | kallikrein-related peptidase 3 | -0.00651555 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00645232 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00641559 |
| C7 | complement component 7 | -0.00641493 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00640694 |
| NEBL | nebulette | -0.00640336 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -0.00637559 |
| RCAN1 | regulator of calcineurin 1 | -0.00635755 |
| RGS10 | regulator of G-protein signaling 10 | -0.00633568 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00633528 |
| ANXA6 | annexin A6 | -0.00632665 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.00630124 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0062719 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00623415 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00621334 |
| CD2 | CD2 molecule | -0.00619657 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00618059 |
| CD96 | CD96 molecule | -0.00616985 |
| RAB22A | RAB22A, member RAS oncogene family | -0.00607208 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00601764 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00599648 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00599507 |
| KLF11 | Kruppel-like factor 11 | -0.00596881 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.0059667 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00595815 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00594009 |
| SDC1 | syndecan 1 | -0.00593495 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.00589802 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00587319 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.0058697 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00586943 |
| LCN2 | lipocalin 2 | -0.00586538 |
| CCNF | cyclin F | -0.00585178 |
| NPR3 | natriuretic peptide receptor 3 | -0.00584975 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00584869 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00583556 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.00582722 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00582006 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00581759 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00581462 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00579384 |
| NEFH | neurofilament, heavy polypeptide | -0.00578666 |
| PCYOX1L | prenylcysteine oxidase 1 like | -0.00577689 |
| BMP7 | bone morphogenetic protein 7 | -0.00577655 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00577381 |
| PGD | phosphogluconate dehydrogenase | -0.00576947 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00576771 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00575767 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | -0.00575549 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00575435 |
| SORD | sorbitol dehydrogenase | -0.00574503 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | -0.00571564 |
| ASRGL1 | asparaginase like 1 | -0.00571133 |
| TKTL1 | transketolase-like 1 | -0.00570323 |
| SPDEF | SAM pointed domain containing ETS transcription factor | -0.00569826 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.005694 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00566991 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -0.00565452 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00564844 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00564315 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00564024 |
| ANOS1 | anosmin 1 | -0.00563482 |
| DES | desmin | -0.00560078 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00560076 |
| PENK | proenkephalin | -0.00559441 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00559042 |
| RTN2 | reticulon 2 | -0.0055899 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00556306 |
| DIPK1A | divergent protein kinase domain 1A | -0.00556142 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00554424 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.00554295 |
| LTA4H | leukotriene A4 hydrolase | -0.00553921 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.0055265 |
| BRD3 | bromodomain containing 3 | -0.00552245 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00550975 |
| PTCH1 | patched 1 | -0.00550911 |
| KYNU | kynureninase | -0.0054941 |
| OPHN1 | oligophrenin 1 | -0.005492 |
| NFIB | nuclear factor I/B | -0.00549116 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00548924 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -0.00548861 |
| ACP2 | acid phosphatase 2, lysosomal | -0.00548703 |
| KLK2 | kallikrein-related peptidase 2 | -0.00548028 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00546251 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.0054594 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | -0.00545761 |
| LBR | lamin B receptor | -0.00545286 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00543865 |
| FOXA1 | forkhead box A1 | -0.00543441 |
| SALL2 | spalt-like transcription factor 2 | -0.00543289 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00542886 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00542863 |
| FOLH1B | folate hydrolase 1B | -0.00542446 |
| NTS | neurotensin | -0.00540445 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00538123 |
| DPEP1 | dipeptidase 1 (renal) | -0.0053748 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00537384 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00537164 |
| CDCA4 | cell division cycle associated 4 | -0.00537036 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.00536515 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.00535811 |
| VNN1 | vanin 1 | -0.00535599 |
| SNX6 | sorting nexin 6 | -0.00535561 |
| NVL | nuclear VCP-like | -0.00534538 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00534028 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -0.00531564 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00531068 |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | -0.0052977 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00527733 |
| LEFTY1 | left-right determination factor 1 | -0.00526955 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00526008 |
| NRCAM | neuronal cell adhesion molecule | -0.00525691 |
| TRMT5 | tRNA methyltransferase 5 | -0.00525098 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00524479 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00524247 |
| LY75 | lymphocyte antigen 75 | -0.00523438 |
| RELN | reelin | -0.00517892 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00517831 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.0051552 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00515026 |
| CTSZ | cathepsin Z | -0.00514756 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | -0.00514688 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00512638 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00511719 |
| EPHB4 | EPH receptor B4 | -0.00510968 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.00510631 |
| MDC1 | mediator of DNA-damage checkpoint 1 | -0.00510436 |
| ACP3 | acid phosphatase 3 | -0.00509615 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00507902 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0050688 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00506838 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00506226 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | -0.00505928 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00505611 |
| RNF43 | ring finger protein 43 | -0.00505349 |
| CALB1 | calbindin 1, 28kDa | -0.00504859 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00504483 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00504005 |
| F2R | coagulation factor II (thrombin) receptor | -0.00503515 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00502129 |
| MAOA | monoamine oxidase A | -0.00501623 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00501603 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00501515 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00501033 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | -0.00499482 |
| HTRA1 | HtrA serine peptidase 1 | -0.00497606 |
