| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | glutathione S-transferase alpha 1|Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2938) |
| External Link | https://ncbi.nlm.nih.gov/gene/2938 |
| Similar Terms | |
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498 genes differentially expressed following the GSTA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0236385 |
| SYNGR3 | synaptogyrin 3 | 0.0162378 |
| ATF3 | activating transcription factor 3 | 0.0144503 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0133947 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0132773 |
| MT1E | metallothionein 1E | 0.0132737 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0130713 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.012829 |
| MT1X | metallothionein 1X | 0.0128224 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.0125295 |
| MT1H | metallothionein 1H | 0.0122886 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0122623 |
| MT1F | metallothionein 1F | 0.0122353 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0121527 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0119931 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0114418 |
| MT1G | metallothionein 1G | 0.011346 |
| S100A10 | S100 calcium binding protein A10 | 0.0112862 |
| ICAM2 | intercellular adhesion molecule 2 | 0.0111401 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0110938 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0109963 |
| ANXA1 | annexin A1 | 0.0108237 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0107241 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0106878 |
| MT1M | metallothionein 1M | 0.0105527 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.0104934 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.0101365 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.0101253 |
| MT2A | metallothionein 2A | 0.0100401 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.0100146 |
| EFNA1 | ephrin-A1 | 0.0099896 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0098178 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00969152 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00966253 |
| FCGBP | Fc fragment of IgG binding protein | 0.00957784 |
| FN1 | fibronectin 1 | 0.00941741 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00937354 |
| MSLN | mesothelin | 0.00932743 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00931528 |
| ITM2C | integral membrane protein 2C | 0.00929206 |
| NEFH | neurofilament, heavy polypeptide | 0.00924483 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00918357 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0091176 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00883837 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00883625 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0086714 |
| ASS1 | argininosuccinate synthase 1 | 0.00863458 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00853543 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00849492 |
| CCN2 | cellular communication network factor 2 | 0.00844041 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00842663 |
| GLOD4 | glyoxalase domain containing 4 | 0.00841869 |
| KRT19 | keratin 19, type I | 0.00840044 |
| SELPLG | selectin P ligand | 0.00838077 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00836699 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00835721 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00830517 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00830229 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00826422 |
| CTH | cystathionine gamma-lyase | 0.00826115 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00824361 |
| DEFB1 | defensin, beta 1 | 0.00823922 |
| MAGED2 | melanoma antigen family D2 | 0.0081682 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00812354 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00809196 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00808493 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00805655 |
| SOAT1 | sterol O-acyltransferase 1 | 0.00802623 |
| QPRT | quinolinate phosphoribosyltransferase | 0.0079937 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00798267 |
| APOD | apolipoprotein D | 0.00797687 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00797176 |
| RHOF | ras homolog family member F (in filopodia) | 0.00796701 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00793703 |
| CCNA2 | cyclin A2 | 0.00791876 |
| OPTN | optineurin | 0.00790728 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00788596 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00785915 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.0078349 |
| ARG2 | arginase 2 | 0.0078302 |
| RNASET2 | ribonuclease T2 | 0.00778457 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00775959 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00775325 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00773639 |
| AREG | amphiregulin | 0.00772519 |
| GOLT1B | golgi transport 1B | 0.00766682 |
| MGLL | monoglyceride lipase | 0.00763103 |
| TMEM255A | transmembrane protein 255A | 0.0076066 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00756076 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0075364 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00752317 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00751471 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00748912 |
| VNN1 | vanin 1 | 0.00747641 |
| STAT4 | signal transducer and activator of transcription 4 | 0.00747474 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00746583 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00740562 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00740073 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00739608 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00736252 |
| PEG3 | paternally expressed 3 | 0.00735988 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00735505 |
| MX1 | MX dynamin-like GTPase 1 | 0.00727636 |
| AOC1 | amine oxidase, copper containing 1 | 0.00723667 |
| PLLP | plasmolipin | 0.007209 |
| IFI44 | interferon-induced protein 44 | 0.00719949 |
| LY75 | lymphocyte antigen 75 | 0.00717591 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.00713086 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00710778 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00708345 |
| KLF10 | Kruppel-like factor 10 | 0.00706632 |
| GPR65 | G protein-coupled receptor 65 | 0.0070269 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00702587 |
| GAP43 | growth associated protein 43 | 0.00698318 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00695934 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00695034 |
| PTHLH | parathyroid hormone-like hormone | 0.00694649 |
| MX2 | MX dynamin-like GTPase 2 | 0.00693791 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00692666 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00691938 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00688752 |
| GATA6 | GATA binding protein 6 | 0.00687083 |
| ETNK1 | ethanolamine kinase 1 | 0.00684427 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00682736 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.00682648 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00679667 |
| TKTL1 | transketolase-like 1 | 0.00679313 |
| DUSP5 | dual specificity phosphatase 5 | 0.00672132 |
| MAL | mal, T-cell differentiation protein | 0.00670726 |
| NPTX2 | neuronal pentraxin II | 0.00666289 |
| PDGFC | platelet derived growth factor C | 0.00665212 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00658168 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00656867 |
| TMEM100 | transmembrane protein 100 | 0.00655693 |
| IL33R | interleukin 33 receptor | 0.0065566 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00654233 |
| A2M | alpha-2-macroglobulin | 0.0065224 |
| CTSS | cathepsin S | 0.006501 |
| MAGEA1 | melanoma antigen family A1 | 0.00648278 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00646915 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00646389 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00645688 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00642718 |
| PNMA8A | PNMA family member 8A | 0.00642372 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0064155 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00640792 |
| OLFML3 | olfactomedin-like 3 | 0.00640554 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00639817 |
| MICB | MHC class I polypeptide-related sequence B | 0.00638654 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00638242 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00638118 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00638045 |
| PITX3 | paired-like homeodomain 3 | 0.00637665 |
| NLGN4X | neuroligin 4, X-linked | 0.00636004 |
| CD93 | CD93 molecule | 0.00634566 |
| DUOX2 | dual oxidase 2 | 0.0063328 |
| ADI1 | acireductone dioxygenase 1 | 0.00633189 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.00633 |
| PRR5L | proline rich 5 like | 0.00629138 |
| CLIC5 | chloride intracellular channel 5 | 0.00627805 |
| NID1 | nidogen 1 | 0.00625676 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | 0.00624306 |
| TSPAN8 | tetraspanin 8 | 0.00620113 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00619496 |
| PLBD1 | phospholipase B domain containing 1 | 0.00619339 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00618794 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00617487 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00616685 |
| PROM1 | prominin 1 | 0.00616315 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00614934 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00614643 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00612968 |
| IFI44L | interferon-induced protein 44-like | 0.00612809 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0061265 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00612134 |
| MAGEA12 | melanoma antigen family A12 | 0.00610706 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00610305 |
| ANXA3 | annexin A3 | 0.00610004 |
| GPX7 | glutathione peroxidase 7 | 0.00608672 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00608523 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00607101 |
| CREM | cAMP responsive element modulator | 0.00604131 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00603946 |
| CLDN5 | claudin 5 | 0.00600888 |
| CFI | complement factor I | 0.00597907 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00595189 |
| MCL1 | myeloid cell leukemia 1 | 0.0059502 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00594778 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00594314 |
| ATP10B | ATPase, class V, type 10B | 0.00594093 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00591447 |
| PMP2 | peripheral myelin protein 2 | 0.00589999 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.00589786 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00589613 |
| GLS | glutaminase | 0.00588248 |
| SLC35F2 | solute carrier family 35, member F2 | 0.00587485 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00586361 |
| CDC14B | cell division cycle 14B | 0.00585644 |
| VCL | vinculin | 0.00585003 |
| NOTCH2NL | notch 2 N-terminal like | 0.00584249 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00583317 |
| CCDC6 | coiled-coil domain containing 6 | 0.00582539 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0058006 |
| F2R | coagulation factor II (thrombin) receptor | 0.00579602 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00579031 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00578256 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00578135 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.00577235 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 | 0.00577231 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00576765 |
| GALC | galactosylceramidase | 0.00576273 |
| KLF6 | Kruppel-like factor 6 | 0.00575363 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00574936 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00574889 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | 0.00574166 |
| S100A11 | S100 calcium binding protein A11 | 0.00572793 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00572059 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00571792 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00570895 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00570797 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | 0.00569543 |
| RAB8B | RAB8B, member RAS oncogene family | 0.00568313 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00568016 |
| LAMC2 | laminin, gamma 2 | 0.00566584 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 | 0.00564975 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00563018 |
| COG2 | component of oligomeric golgi complex 2 | 0.00562904 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00562542 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00562437 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.00561642 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00561575 |
| CTBS | chitobiase, di-N-acetyl- | 0.00560898 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00558502 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00557669 |
| DENND1B | DENN/MADD domain containing 1B | 0.00556114 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00555412 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00553114 |
| EGR2 | early growth response 2 | 0.00552477 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00552347 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0055047 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00550344 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00550254 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00549772 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00549023 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00547613 |
| ADCY7 | adenylate cyclase 7 | 0.00547594 |
| SNX10 | sorting nexin 10 | 0.00547255 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00546813 |
| DOCK10 | dedicator of cytokinesis 10 | 0.00546037 |
| GSPT2 | G1 to S phase transition 2 | 0.00545308 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0204704 |
| MMP9 | matrix metallopeptidase 9 | -0.0129939 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0127691 |
| TATDN2 | TatD DNase domain containing 2 | -0.0121094 |
| LTF | lactotransferrin | -0.011978 |
| TNC | tenascin C | -0.0115033 |
| MAP7 | microtubule-associated protein 7 | -0.0111857 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0109859 |
| LUM | lumican | -0.0108993 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0106729 |
| PTK2 | protein tyrosine kinase 2 | -0.0104705 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00995962 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00988911 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00982344 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0098028 |
| PAX5 | paired box 5 | -0.00974019 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00970558 |
| ANO10 | anoctamin 10 | -0.00958026 |
| HP | haptoglobin | -0.0095412 |
| FASN | fatty acid synthase | -0.00951767 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00939578 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00938766 |
| S100A2 | S100 calcium binding protein A2 | -0.00926926 |
| TCF4 | transcription factor 4 | -0.00909893 |
| GPI | glucose-6-phosphate isomerase | -0.00908962 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0090723 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00898576 |
| CCNB1 | cyclin B1 | -0.00895409 |
| ARG1 | arginase 1 | -0.0089135 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00886018 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00880024 |
| LOX | lysyl oxidase | -0.00878764 |
| PLPP3 | phospholipid phosphatase 3 | -0.00875259 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00874729 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00871724 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00868528 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00857901 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00843514 |
| NNMT | nicotinamide N-methyltransferase | -0.00827136 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00826631 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00815064 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00808285 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00806023 |
| PCLAF | PCNA clamp associated factor | -0.00804359 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00799994 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | -0.00787853 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00786802 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00780273 |
| CBX6 | chromobox homolog 6 | -0.00771969 |
| KIF20A | kinesin family member 20A | -0.00767964 |
| CST6 | cystatin E/M | -0.00766733 |
| AUTS2 | autism susceptibility candidate 2 | -0.00753154 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00750046 |
| DACH1 | dachshund family transcription factor 1 | -0.00748936 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00748702 |
| CHN1 | chimerin 1 | -0.00746456 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00740559 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00739019 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00738366 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00736839 |
| PTMS | parathymosin | -0.00733225 |
| PKM | pyruvate kinase, muscle | -0.00726188 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00723329 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00723229 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00722461 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00718933 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.0071718 |
| KRT6A | keratin 6A, type II | -0.00701324 |
| PNN | pinin, desmosome associated protein | -0.00700793 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00696677 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00693938 |
| RAPSN | receptor-associated protein of the synapse | -0.00691247 |
| DHFR | dihydrofolate reductase | -0.00689741 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00686708 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00682677 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00681699 |
| CDHR1 | cadherin-related family member 1 | -0.00681267 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0067596 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00672937 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00672657 |
| TMEM47 | transmembrane protein 47 | -0.00672507 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | -0.00670896 |
| CENPB | centromere protein B, 80kDa | -0.00670525 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.00669512 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00669403 |
| SUN2 | Sad1 and UNC84 domain containing 2 | -0.00669266 |
| CAMP | cathelicidin antimicrobial peptide | -0.0066852 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00666439 |
| GGCT | gamma-glutamylcyclotransferase | -0.0066581 |
| PLCB4 | phospholipase C, beta 4 | -0.00662974 |
| STK26 | serine/threonine protein kinase 26 | -0.00659839 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00658106 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00657688 |
| CCNB2 | cyclin B2 | -0.00657235 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00656274 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | -0.00653867 |
| EREG | epiregulin | -0.00649229 |
| TNS3 | tensin 3 | -0.00649131 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00648212 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00647675 |
| RPL10 | ribosomal protein L10 | -0.00646511 |
| ROGDI | rogdi homolog (Drosophila) | -0.00643999 |
| PLEK | pleckstrin | -0.00642202 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0064168 |
| DSC1 | desmocollin 1 | -0.006414 |
| FGF13 | fibroblast growth factor 13 | -0.00639634 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00637863 |
| MPO | myeloperoxidase | -0.0063718 |
| TPI1 | triosephosphate isomerase 1 | -0.00637041 |
| CRYM | crystallin, mu | -0.00636227 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00634037 |
| CENPM | centromere protein M | -0.00633404 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00632546 |
| CD200 | CD200 molecule | -0.00631783 |
| H1-0 | H1.0 linker histone | -0.00631425 |
| SDC2 | syndecan 2 | -0.00629834 |
| KLHDC3 | kelch domain containing 3 | -0.00629107 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00627094 |
| CP | ceruloplasmin (ferroxidase) | -0.00625108 |
| PCP4 | Purkinje cell protein 4 | -0.00621487 |
| CALR | calreticulin | -0.00618344 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | -0.00617286 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.0061694 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0061684 |
| DSP | desmoplakin | -0.00616484 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00614181 |
| ZNF692 | zinc finger protein 692 | -0.00614004 |
| PPL | periplakin | -0.00613815 |
| CLIC4 | chloride intracellular channel 4 | -0.0061381 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00613106 |
| PLPP2 | phospholipid phosphatase 2 | -0.0061284 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00612131 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00610897 |
| ASPH | aspartate beta-hydroxylase | -0.00610519 |
| NEBL | nebulette | -0.00608028 |
| LOXL2 | lysyl oxidase-like 2 | -0.00607279 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00605719 |
| LRP3 | low density lipoprotein receptor-related protein 3 | -0.0060483 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00604201 |
| PLEC | plectin | -0.00602297 |
| TMEM259 | transmembrane protein 259 | -0.00597622 |
| ABHD17A | abhydrolase domain containing 17A | -0.00597166 |
| CALML5 | calmodulin-like 5 | -0.00597132 |
| PLN | phospholamban | -0.0059647 |
| TOX3 | TOX high mobility group box family member 3 | -0.00594337 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00593633 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.0059277 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00590365 |
| EMX2 | empty spiracles homeobox 2 | -0.00590309 |
| HMGB2 | high mobility group box 2 | -0.00590099 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -0.00589777 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.0058932 |
| ATP10D | ATPase, class V, type 10D | -0.00586948 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00586043 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.00584702 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00584575 |
| PERP | PERP, TP53 apoptosis effector | -0.00584375 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00581833 |
| NEO1 | neogenin 1 | -0.00579695 |
| CALD1 | caldesmon 1 | -0.00579368 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00579121 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00578385 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00576887 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00576499 |
| HMGB3 | high mobility group box 3 | -0.00576317 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00575182 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.00573544 |
| RTL8C | retrotransposon Gag like 8C | -0.00572895 |
| PITX1 | paired-like homeodomain 1 | -0.00572621 |
| PLXNB1 | plexin B1 | -0.00569992 |
| AQP5 | aquaporin 5 | -0.00569184 |
| KRT16 | keratin 16, type I | -0.00568176 |
| BPI | bactericidal/permeability-increasing protein | -0.00567648 |
| COL1A2 | collagen, type I, alpha 2 | -0.00567375 |
| SETBP1 | SET binding protein 1 | -0.00564953 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00561588 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00561533 |
| PRR16 | proline rich 16 | -0.0056028 |
| PMP22 | peripheral myelin protein 22 | -0.0056028 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00560054 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00558244 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00558027 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00557519 |
| GPSM2 | G-protein signaling modulator 2 | -0.00557314 |
| CNN3 | calponin 3, acidic | -0.00557028 |
| TPM2 | tropomyosin 2 (beta) | -0.00555087 |
| METTL3 | methyltransferase like 3 | -0.00554955 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | -0.00552379 |
| DST | dystonin | -0.00552344 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | -0.00551184 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00550505 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0055023 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00549506 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | -0.00549059 |
| TMEM45A | transmembrane protein 45A | -0.00548664 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00547809 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.00546337 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00545847 |
| RETN | resistin | -0.00545714 |
| CD81 | CD81 molecule | -0.00543586 |
| PPP5C | protein phosphatase 5, catalytic subunit | -0.00542976 |
| C20ORF27 | chromosome 20 open reading frame 27 | -0.0054237 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.00539516 |
| HPN | hepsin | -0.00539237 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 | -0.00538274 |
| RGS13 | regulator of G-protein signaling 13 | -0.00537995 |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit | -0.00537681 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00537146 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00535333 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00534626 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00534415 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00534397 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00534213 |
| TRMT5 | tRNA methyltransferase 5 | -0.00534052 |
| NOTCH3 | notch 3 | -0.00533884 |
| EXPH5 | exophilin 5 | -0.00533304 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.00532816 |
| TSPAN9 | tetraspanin 9 | -0.005327 |
| CCNL2 | cyclin L2 | -0.00532699 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00532591 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00532225 |
| PRDX2 | peroxiredoxin 2 | -0.005309 |
| S100A9 | S100 calcium binding protein A9 | -0.00530115 |
| RRM1 | ribonucleotide reductase M1 | -0.00527533 |
| GOLGA8A | golgin A8 family, member A | -0.00526318 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.0052473 |
| RIN2 | Ras and Rab interactor 2 | -0.00523467 |
| KIAA0930 | KIAA0930 | -0.00522404 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00521886 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00521845 |
| CALML3 | calmodulin-like 3 | -0.0052159 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00521507 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00520289 |
| MYBPC2 | myosin binding protein C, fast type | -0.00520189 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00519637 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00519268 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00517554 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00517053 |
| CST7 | cystatin F (leukocystatin) | -0.00515979 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00515706 |
| ECT2 | epithelial cell transforming 2 | -0.00514804 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.00514407 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00514346 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00513562 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00513306 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00513284 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.00512736 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00512293 |
