GSTA4 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description glutathione S-transferase alpha 4|Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2941)
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67 co-expressed genes for GSTA4 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABHD14A abhydrolase domain containing 14A
AMER2 APC membrane recruitment protein 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ASTN2 astrotactin 2
ATAT1 alpha tubulin acetyltransferase 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRD2 bromodomain containing 2
BRPF3 bromodomain and PHD finger containing, 3
C11ORF95 chromosome 11 open reading frame 95
C2CD5 C2 calcium-dependent domain containing 5
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CLEC16A C-type lectin domain family 16, member A
CSRNP2 cysteine-serine-rich nuclear protein 2
DCAF7 DDB1 and CUL4 associated factor 7
DCTN4 dynactin 4 (p62)
DCX doublecortin
DLG5 discs, large homolog 5 (Drosophila)
ERBB4 erb-b2 receptor tyrosine kinase 4
EXOSC6 exosome component 6
FAM172A family with sequence similarity 172, member A
FOXO3 forkhead box O3
GSTA4 glutathione S-transferase alpha 4
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IPO9 importin 9
IQCK IQ motif containing K
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL11 kelch-like family member 11
LPPR4 lipid phosphate phosphatase-related protein type 4
MAP6 microtubule-associated protein 6
MED13 mediator complex subunit 13
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MSI1 musashi RNA-binding protein 1
MTMR3 myotubularin related protein 3
NCAM1 neural cell adhesion molecule 1
NFIB nuclear factor I/B
NGRN neugrin, neurite outgrowth associated
NISCH nischarin
PGRMC2 progesterone receptor membrane component 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF10 PHD finger protein 10
PHF2 PHD finger protein 2
PKNOX1 PBX/knotted 1 homeobox 1
POGZ pogo transposable element with ZNF domain
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRRC2B proline-rich coiled-coil 2B
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM4B RNA binding motif protein 4B
RBM8A RNA binding motif protein 8A
RERE arginine-glutamic acid dipeptide (RE) repeats
SLC35E2 solute carrier family 35, member E2
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
TMEM237 transmembrane protein 237
TNPO2 transportin 2
TSPYL4 TSPY-like 4
UBE2E3 ubiquitin-conjugating enzyme E2E 3
USP22 ubiquitin specific peptidase 22
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
WBP2 WW domain binding protein 2
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WSB2 WD repeat and SOCS box containing 2
ZBTB5 zinc finger and BTB domain containing 5
ZFAND5 zinc finger, AN1-type domain 5
ZNF84 zinc finger protein 84