GTEx BloodVessel 20-29 vs 30-39 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

111 genes with high or low expression in GTEx BloodVessel 20-29 vs 30-39 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
PTCHD4 patched domain containing 4 11.0098
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 6.6603
POT1-AS1 POT1 antisense RNA 1 6.6603
EOLA2-DT EOLA2 divergent transcript 5.47206
CADPS2 Ca++-dependent secretion activator 2 5.3089
UNC13A unc-13 homolog A (C. elegans) 5.3089
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 5.3089
GPNMB glycoprotein (transmembrane) nmb 5.3089
LNCTAM34A long non coding transcriptional activator of miR34a 5.3089
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 4.24618
UBA7 ubiquitin-like modifier activating enzyme 7 4.24618
COL16A1 collagen, type XVI, alpha 1 4.24618
CABCOCO1 ciliary associated calcium binding coiled-coil 1 4.09664
GSAP gamma-secretase activating protein 4.0765
WSCD2 WSC domain containing 2 4.0765
FRZB frizzled-related protein 4.0765
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 4.0765
SEPTIN4 septin 4 4.0765
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 4.0765
MIR34AHG MIR34A host gene 4.0765
GLRB glycine receptor, beta 4.0765
HLA-K major histocompatibility complex, class I, K (pseudogene) 4.0765
LMO3 LIM domain only 3 (rhombotin-like 2) 4.0765
TEX9 testis expressed 9 4.04466
EPOR erythropoietin receptor 4.02409
GSTM2 glutathione S-transferase mu 2 (muscle) 3.88457
PCDH9 protocadherin 9 3.88457
TAS2R20 taste receptor, type 2, member 20 3.88457
ANKRD36 ankyrin repeat domain 36 3.83097
SCN3A sodium channel, voltage gated, type III alpha subunit 3.6946
PLA2R1 phospholipase A2 receptor 1, 180kDa 3.65041
KCNK2 potassium channel, two pore domain subfamily K, member 2 3.63256
PROS1 protein S (alpha) 3.63162
PRMT5-DT PRMT5 divergent transcript 3.61605
DDB2 damage-specific DNA binding protein 2, 48kDa 3.61605
RPL8P5 ribosomal protein L8 pseudogene 5 3.57829
COL11A1 collagen, type XI, alpha 1 3.57829
SCN9A sodium channel, voltage gated, type IX alpha subunit 3.45156
AHNAK2 AHNAK nucleoprotein 2 3.45156
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 3.45156
TUBG2 tubulin, gamma 2 3.4497
UNC5B-AS1 UNC5B antisense RNA 1 3.44476
SCART1 scavenger receptor protein family member 3.42949
LOC101929532 uncharacterized LOC101929532 3.42949
HDAC9 histone deacetylase 9 3.38516
NMRK1 nicotinamide riboside kinase 1 3.36911
FGF14 fibroblast growth factor 14 3.36911
MAP4K3-DT MAP4K3 divergent transcript 3.33501
JAKMIP2 janus kinase and microtubule interacting protein 2 3.33501
FDXR ferredoxin reductase 3.29703
EDA2R ectodysplasin A2 receptor 3.25931
ANKRD36C ankyrin repeat domain 36C 3.19168
AGA aspartylglucosaminidase 3.18357
NRGN neurogranin (protein kinase C substrate, RC3) 3.16505
FAM133A family with sequence similarity 133, member A 3.15925
EPHA6 EPH receptor A6 3.15925
COL24A1 collagen, type XXIV, alpha 1 3.15925
IL7 interleukin 7 3.15925
TSC22D1-AS1 TSC22D1 antisense RNA 1 3.15925
NICN1 nicolin 1 3.15666
CD46 CD46 molecule, complement regulatory protein 3.15666
C8ORF34 chromosome 8 open reading frame 34 3.15666
MROH7 maestro heat-like repeat family member 7 3.15548
ESR1 estrogen receptor 1 3.15548
PODNL1 podocan-like 1 3.10585
NOTCH2NLB notch 2 N-terminal like B 3.03173
OMG oligodendrocyte myelin glycoprotein 3.03173
MX1 MX dynamin-like GTPase 1 3.00033

decreased expression

Symbol Name Standardized Value
AP3M1 adaptor-related protein complex 3, mu 1 subunit -5.47206
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) -5.3089
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -4.91586
MRPS17 mitochondrial ribosomal protein S17 -4.66553
FAM120A family with sequence similarity 120A -4.24618
LSM12 LSM12 homolog (S. cerevisiae) -4.24618
TSFM Ts translation elongation factor, mitochondrial -4.13925
ELOA elongin A -4.0765
MRPS35 mitochondrial ribosomal protein S35 -4.0765
CDC25A cell division cycle 25A -4.0765
ACOX1 acyl-CoA oxidase 1, palmitoyl -4.0765
METTL2A methyltransferase like 2A -4.0765
ETFA electron-transfer-flavoprotein, alpha polypeptide -3.97347
ZNF778 zinc finger protein 778 -3.88457
DCAF7 DDB1 and CUL4 associated factor 7 -3.88457
OCRL oculocerebrorenal syndrome of Lowe -3.6946
ESRRA estrogen-related receptor alpha -3.57401
PRPF4 pre-mRNA processing factor 4 -3.49214
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.47856
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -3.38516
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -3.38501
TADA2A transcriptional adaptor 2A -3.36911
NKIRAS2 NFKB inhibitor interacting Ras-like 2 -3.36911
TRIM62 tripartite motif containing 62 -3.36911
RMDN3 regulator of microtubule dynamics 3 -3.36911
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -3.36911
MPV17L2 MPV17 mitochondrial membrane protein-like 2 -3.33501
BVES blood vessel epicardial substance -3.29703
DLAT dihydrolipoamide S-acetyltransferase -3.15925
TP53INP2 tumor protein p53 inducible nuclear protein 2 -3.15925
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -3.15925
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -3.15666
DERL1 derlin 1 -3.15548
PITPNA phosphatidylinositol transfer protein, alpha -3.15548
PREP prolyl endopeptidase -3.15548
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -3.14804
ZCCHC17 zinc finger, CCHC domain containing 17 -3.10585
WDR82 WD repeat domain 82 -3.10585
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.10585
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -3.09115
AP3B1 adaptor-related protein complex 3, beta 1 subunit -3.06098
MTCH2 mitochondrial carrier 2 -3.03173
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -3.03173