GTEx Esophagus 20-29 vs 60-69 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

500 genes with high or low expression in GTEx Esophagus 20-29 vs 60-69 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
EYA4 EYA transcriptional coactivator and phosphatase 4 46.0884
TBX19 T-box 19 28.5439
LRRC2 leucine rich repeat containing 2 28.5439
FGF14 fibroblast growth factor 14 28.5439
TAS2R20 taste receptor, type 2, member 20 28.1483
HBA2 hemoglobin, alpha 2 28.084
HBB hemoglobin, beta 28.038
OMG oligodendrocyte myelin glycoprotein 27.469
PTCHD4 patched domain containing 4 27.469
GDF15 growth differentiation factor 15 27.2405
LINC01239 long intergenic non-protein coding RNA 1239 27.2405
LRRC70 leucine rich repeat containing 70 26.0849
ZNF678 zinc finger protein 678 25.3544
CP ceruloplasmin (ferroxidase) 24.9355
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 24.7165
S100A13 S100 calcium binding protein A13 24.5493
ZBTB48 zinc finger and BTB domain containing 48 24.5493
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 24.2363
CLEC2B C-type lectin domain family 2, member B 24.2357
SPON2 spondin 2, extracellular matrix protein 24.2357
BORCS8-MEF2B BORCS8-MEF2B readthrough 23.5246
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 23.5189
ZFYVE27 zinc finger, FYVE domain containing 27 23.479
CA5B carbonic anhydrase VB, mitochondrial 23.4209
KANTR KDM5C adjacent non-coding transcript 23.3941
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 23.1843
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 23.1475
KHDC4 KH domain containing 4, pre-mRNA splicing factor 23.1071
AFAP1-AS1 AFAP1 antisense RNA 1 22.7356
DPP4 dipeptidyl-peptidase 4 22.4708
LVRN laeverin 22.1719
PON3 paraoxonase 3 22.0275
TDRD10 tudor domain containing 10 22.0081
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 21.9231
RORB RAR-related orphan receptor B 21.9231
MFAP4 microfibrillar-associated protein 4 21.8785
RNF152 ring finger protein 152 21.6899
MRC2 mannose receptor, C type 2 21.6128
PAMR1 peptidase domain containing associated with muscle regeneration 1 21.5636
LSMEM1 leucine-rich single-pass membrane protein 1 21.4875
CENATAC centrosomal AT-AC splicing factor 21.4711
ZNF721 zinc finger protein 721 21.4525
KIF23-AS1 KIF23 and PAQR5 antisense RNA 1 21.425
VWCE von Willebrand factor C and EGF domains 21.3555
LIPC lipase, hepatic 21.2678
PKP4-AS1 PKP4 antisense RNA 1 21.2072
ANKRD23 ankyrin repeat domain 23 21.0538
ZNF90 zinc finger protein 90 20.8317
SFRP2 secreted frizzled-related protein 2 20.6592
EGFR-AS1 EGFR antisense RNA 1 20.617
ZNF26 zinc finger protein 26 20.4318
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 20.2725
LINC02696 long intergenic non-protein coding RNA 2696 20.2368
ASXL3 additional sex combs like transcriptional regulator 3 20.1685
ATP1A1-AS1 ATP1A1 antisense RNA 1 20.1263
LINC01140 long intergenic non-protein coding RNA 1140 20.1134
ANXA2R-AS1 ANXA2R antisense RNA 1 20.1039
TMEM44 transmembrane protein 44 19.9598
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding) 19.9293
C16ORF89 chromosome 16 open reading frame 89 19.8863
PRPF3 pre-mRNA processing factor 3 19.6356
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 19.5231
TRIM58 tripartite motif containing 58 19.5212
FAM111A family with sequence similarity 111, member A 19.5117
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 19.483
DNM1 dynamin 1 19.4422
FOXD2-AS1 FOXD2 antisense RNA 1 (head to head) 19.4212
TTLL3 tubulin tyrosine ligase-like family member 3 19.3843
DPY19L3 dpy-19-like 3 (C. elegans) 19.3592
TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase 19.2002
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 19.1018
CFD complement factor D (adipsin) 19.0008
TMEM243 transmembrane protein 243, mitochondrial 19.0008
OXER1 oxoeicosanoid (OXE) receptor 1 18.8666
NLRP1 NLR family, pyrin domain containing 1 18.7649
ANXA2R annexin A2 receptor 18.754
HOXD8 homeobox D8 18.7141
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 18.6916
B3GAT2 beta-1,3-glucuronyltransferase 2 18.6152
LUC7L LUC7-like (S. cerevisiae) 18.6091
SPDYA speedy/RINGO cell cycle regulator family member A 18.4677
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 18.3981
CDRT4 CMT1A duplicated region transcript 4 18.375
HYMAI hydatidiform mole associated and imprinted (non-protein coding) 18.3679
EXOC3L4 exocyst complex component 3-like 4 18.3679
KRBOX5 KRAB box domain containing 5 18.2351
PLXDC2 plexin domain containing 2 18.227
CHMP3-AS1 CHMP3 and RNF103 antisense RNA 1 18.227
ADD3 adducin 3 (gamma) 18.1852
ALMS1-IT1 ALMS1 intronic transcript 1 18.136
TRPV1 transient receptor potential cation channel, subfamily V, member 1 18.0707
LINC00662 long intergenic non-protein coding RNA 662 17.9217
C2ORF92 chromosome 2 open reading frame 92 17.9094
LINC-PINT long intergenic non-protein coding RNA, p53 induced transcript 17.9094
N4BP2L2-IT2 N4BPL2 intronic transcript 2 17.8943
LIX1L-AS1 LIX1L antisense RNA 1 17.8884
TMEM81 transmembrane protein 81 17.8488
MAFTRR MAF transcriptional regulator RNA 17.8344
LINC00174 long intergenic non-protein coding RNA 174 17.8202
RGS1 regulator of G-protein signaling 1 17.7313
IL15RA interleukin 15 receptor, alpha 17.673
SMG9 SMG9 nonsense mediated mRNA decay factor 17.6124
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 17.5951
ODR4 odr-4 GPCR localization factor homolog 17.485
THAP9-AS1 THAP9 antisense RNA 1 17.4101
FOXP1-DT FOXP1 divergent transcript 17.2885
NSUN6 NOP2/Sun domain family, member 6 17.2031
LUM lumican 17.1368
HOXD3 homeobox D3 17.1312
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1 17.1271
RASD1 RAS, dexamethasone-induced 1 17.1114
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 17.0901
MANEA-DT MANEA divergent transcript 17.0883
TSHZ2 teashirt zinc finger homeobox 2 17.0882
LMX1A LIM homeobox transcription factor 1, alpha 17.0591
USP3-AS1 USP3 antisense RNA 1 17.0591
TMEM123-DT TMEM123 divergent transcript 17.0343
TMEM74B transmembrane protein 74B 16.9959
HCG27 HLA complex group 27 (non-protein coding) 16.995
CLEC1A C-type lectin domain family 1, member A 16.8997
GUSB glucuronidase, beta 16.8598
FBLN2 fibulin 2 16.811
ARHGAP12 Rho GTPase activating protein 12 16.7879
IDUA iduronidase, alpha-L- 16.7471
FAM180A family with sequence similarity 180, member A 16.7391
SNED1 sushi, nidogen and EGF-like domains 1 16.7391
CD69 CD69 molecule 16.7391
MICA MHC class I polypeptide-related sequence A 16.7026
NPIPB5 nuclear pore complex interacting protein family, member B5 16.6329
LEAP2 liver expressed antimicrobial peptide 2 16.6241
ZNF519 zinc finger protein 519 16.6196
TMEM91 transmembrane protein 91 16.5001
DLL4 delta-like 4 (Drosophila) 16.4984
CATSPER2 cation channel, sperm associated 2 16.4275
ZNF789 zinc finger protein 789 16.4045
LRRC75B leucine rich repeat containing 75B 16.393
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D 16.3031
TMEM116 transmembrane protein 116 16.2593
KCTD13 potassium channel tetramerization domain containing 13 16.2366
PCED1B PC-esterase domain containing 1B 16.155
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 16.1498
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 16.0399
PLXNA3 plexin A3 16.0008
MELTF-AS1 MELTF antisense RNA 1 15.988
KHDC1-AS1 KHDC1 antisense RNA 1 15.9873
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 15.9797
PTPRG-AS1 PTPRG antisense RNA 1 15.9786
NKTR natural killer cell triggering receptor 15.9681
TLDC2 TBC/LysM-associated domain containing 2 15.9667
E2F5 E2F transcription factor 5, p130-binding 15.9517
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 15.9466
TBX1 T-box 1 15.9441
WDFY3-AS2 WDFY3 antisense RNA 2 15.9384
EDA2R ectodysplasin A2 receptor 15.9299
STC1 stanniocalcin 1 15.8434
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 15.7672
OR7E12P olfactory receptor, family 7, subfamily E, member 12 pseudogene 15.7554
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 15.719
RYR3-DT RYR3 divergent transcript 15.6933
SEMA6A-AS1 SEMA6A antisense RNA 1 15.6814
PRR3 proline rich 3 15.668
ELOVL7 ELOVL fatty acid elongase 7 15.6551
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 15.6372
GXYLT1 glucoside xylosyltransferase 1 15.5928
GOT1-DT GOT1 divergent transcript 15.5653
IRF3 interferon regulatory factor 3 15.5609
SEMA3F-AS1 SEMA3F antisense RNA 1 15.5527
TMEM234 transmembrane protein 234 15.5139
LINC02593 long intergenic non-protein coding RNA 2593 15.5084
CYGB cytoglobin 15.4965
SOX13 SRY (sex determining region Y)-box 13 15.4827
CTSK cathepsin K 15.4827
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 15.4827
FAM193B family with sequence similarity 193, member B 15.472
CLEC2D C-type lectin domain family 2, member D 15.4669
PLA2G15 phospholipase A2, group XV 15.3991
NUTM2B-AS1 NUTM2B antisense RNA 1 15.3598
PCNX2 pecanex 2 15.3465
IRX6 iroquois homeobox 6 15.3328
RPS3AP38 ribosomal protein S3a pseudogene 38 15.2999
DISC1 disrupted in schizophrenia 1 15.2722
STAT2 signal transducer and activator of transcription 2, 113kDa 15.2569
TVP23C trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) 15.2281
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 15.2226
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 15.2067
MRNIP MRN complex interacting protein 15.161
LINC00449 long intergenic non-protein coding RNA 449 15.1561
NPFF neuropeptide FF-amide peptide precursor 15.1184
MEG3 maternally expressed 3 (non-protein coding) 15.1154
SNORA33 small nucleolar RNA, H/ACA box 33 15.0596
LINC02981 long intergenic non-protein coding RNA 2981 15.0458
SEC24B-AS1 SEC24B antisense RNA 1 15.0267
LETMD1 LETM1 domain containing 1 15.0101
SLITRK4 SLIT and NTRK-like family, member 4 15.0057
ZNF738 zinc finger protein 738 14.9904
SAP25 Sin3A-associated protein, 25kDa 14.9842
DNAH17 dynein, axonemal, heavy chain 17 14.9769
LPAR1 lysophosphatidic acid receptor 1 14.9712
JDP2 Jun dimerization protein 2 14.9377
LRRC37A3 leucine rich repeat containing 37, member A3 14.9342
KIAA1328 KIAA1328 14.9166
BTN3A2 butyrophilin, subfamily 3, member A2 14.8863
PCDHB2 protocadherin beta 2 14.8842
PDE7A phosphodiesterase 7A 14.8738
MDM4 MDM4, p53 regulator 14.8656
ESR1 estrogen receptor 1 14.8656
FGF17 fibroblast growth factor 17 14.8523
SNORA8 small nucleolar RNA, H/ACA box 8 14.8382
LINC01091 long intergenic non-protein coding RNA 1091 14.8343
CPLX1 complexin 1 14.8108
MMP17 matrix metallopeptidase 17 (membrane-inserted) 14.7147
ADORA1 adenosine A1 receptor 14.6718
MAP3K7CL MAP3K7 C-terminal like 14.6298
ACSS3 acyl-CoA synthetase short-chain family member 3 14.6229
CDK5RAP3 CDK5 regulatory subunit associated protein 3 14.6085
ATXN3 ataxin 3 14.5922
CEP95 centrosomal protein 95kDa 14.5688
PARAIL palmitic acid regulated anti-inflammatory lncRNA 14.5688
PFN4 profilin family, member 4 14.555
C6ORF163 chromosome 6 open reading frame 163 14.555
PCBP1-AS1 PCBP1 antisense RNA 1 14.555
CCDC102B coiled-coil domain containing 102B 14.5331
PCED1A PC-esterase domain containing 1A 14.5169
CHKB choline kinase beta 14.504
CLEC4F C-type lectin domain family 4, member F 14.504
LTBP2 latent transforming growth factor beta binding protein 2 14.4911
LTBP4 latent transforming growth factor beta binding protein 4 14.4907
C12ORF76 chromosome 12 open reading frame 76 14.472
ADRA1A adrenoceptor alpha 1A 14.4607
CHROMR cholesterol induced regulator of metabolism RNA 14.4568
PCSK5 proprotein convertase subtilisin/kexin type 5 14.4568
BTN3A1 butyrophilin, subfamily 3, member A1 14.4568
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 14.4549
TTC21A tetratricopeptide repeat domain 21A 14.3799
ZNF785 zinc finger protein 785 14.3304
SNHG28 small nucleolar RNA host gene 28 14.3079
TVP23A trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) 14.297
MCOLN3 mucolipin 3 14.2653
CEP83 centrosomal protein 83kDa 14.2283
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 14.2283
PRANCR progenitor renewal associated non-coding RNA 14.2227
CHSY3 chondroitin sulfate synthase 3 14.2205
RABL2B RAB, member of RAS oncogene family-like 2B 14.2065
BHLHE22 basic helix-loop-helix family, member e22 14.1939
OSBPL7 oxysterol binding protein-like 7 14.1908
LENG8-AS1 LENG8 antisense RNA 1 14.1618
TRIM52 tripartite motif containing 52 14.1462
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 14.1434
EMID1 EMI domain containing 1 14.1372
ZGLP1 zinc finger, GATA-like protein 1 14.1252

decreased expression

Symbol Name Standardized Value
CLP1 cleavage and polyadenylation factor I subunit 1 -29.1806
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) -28.5439
TBCC tubulin folding cofactor C -28.2763
ZBTB39 zinc finger and BTB domain containing 39 -28.1483
PARP1 poly (ADP-ribose) polymerase 1 -28.1483
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -27.5355
CHAMP1 chromosome alignment maintaining phosphoprotein 1 -27.4725
HPS6 Hermansky-Pudlak syndrome 6 -27.2768
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -27.2458
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -27.2405
SEPHS2 selenophosphate synthetase 2 -27.1581
RIOX1 ribosomal oxygenase 1 -27.0865
EID2 EP300 interacting inhibitor of differentiation 2 -27.0865
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -26.9345
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -26.5653
RPUSD2 RNA pseudouridylate synthase domain containing 2 -26.5281
PCBP1 poly(rC) binding protein 1 -26.0581
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -25.9444
SMG8 SMG8 nonsense mediated mRNA decay factor -25.8112
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -25.0643
CLTC clathrin, heavy chain (Hc) -25.0051
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -24.9974
DLD dihydrolipoamide dehydrogenase -24.9355
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -24.7846
HCCS holocytochrome c synthase -24.6416
RNF139 ring finger protein 139 -24.1379
ZNF551 zinc finger protein 551 -24.131
COPS4 COP9 signalosome subunit 4 -23.9471
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -23.8914
BECN1 beclin 1, autophagy related -23.8509
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -23.7675
RRAGA Ras-related GTP binding A -23.7486
NCOA4 nuclear receptor coactivator 4 -23.6127
VIRMA vir like m6A methyltransferase associated -23.5189
PDHB pyruvate dehydrogenase (lipoamide) beta -23.4789
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -23.4209
ZNF229 zinc finger protein 229 -23.1071
MAD2L1BP MAD2L1 binding protein -23.0796
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -22.9928
USP9X ubiquitin specific peptidase 9, X-linked -22.935
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -22.7491
KIFBP kinesin family binding protein -22.7467
WDR82 WD repeat domain 82 -22.6325
MIR17HG miR-17-92 cluster host gene -22.6183
WBP11 WW domain binding protein 11 -22.5853
ZNF304 zinc finger protein 304 -22.5559
GTF2I general transcription factor IIi -22.5287
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -22.4708
FBXL18 F-box and leucine-rich repeat protein 18 -22.4708
MALSU1 mitochondrial assembly of ribosomal large subunit 1 -22.4442
TRIP12 thyroid hormone receptor interactor 12 -22.3204
MCMBP minichromosome maintenance complex binding protein -22.3204
FASTKD5 FAST kinase domains 5 -22.3204
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -22.1726
TMEM183A transmembrane protein 183A -22.0275
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -21.9526
PHAX phosphorylated adaptor for RNA export -21.9526
SMAD1 SMAD family member 1 -21.9526
METAP2 methionyl aminopeptidase 2 -21.9518
MRPL35 mitochondrial ribosomal protein L35 -21.885
ZNF134 zinc finger protein 134 -21.8211
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -21.6005
DCLRE1A DNA cross-link repair 1A -21.5654
THUMPD3 THUMP domain containing 3 -21.5636
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -21.5636
ACTRT3 actin-related protein T3 -21.4896
CUL2 cullin 2 -21.4666
BIRC6 baculoviral IAP repeat containing 6 -21.425
EIF5 eukaryotic translation initiation factor 5 -21.3321
NOMO2 NODAL modulator 2 -21.3294
PUF60 poly-U binding splicing factor 60KDa -21.3237
ACO2 aconitase 2, mitochondrial -21.3114
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -21.3114
CCT7 chaperonin containing TCP1, subunit 7 (eta) -21.3114
CDC23 cell division cycle 23 -21.2072
CCR2 chemokine (C-C motif) receptor 2 -21.1166
MOCS3 molybdenum cofactor synthesis 3 -20.7685
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -20.7631
TSLIG3A tRNA splicing ligase complex subunit 3A -20.6288
DDB1 damage-specific DNA binding protein 1, 127kDa -20.5646
TUBB6 tubulin, beta 6 class V -20.5623
UFSP1 UFM1-specific peptidase 1 (non-functional) -20.4062
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -20.4062
MED1 mediator complex subunit 1 -20.3977
RIOK2 RIO kinase 2 -20.3617
TRMT61B tRNA methyltransferase 61B -20.339
C5ORF22 chromosome 5 open reading frame 22 -20.3176
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -20.3176
TMEM186 transmembrane protein 186 -20.2616
DOLK dolichol kinase -20.251
RNF26 ring finger protein 26 -20.2368
STRAP serine/threonine kinase receptor associated protein -20.1534
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -20.1213
CHD4 chromodomain helicase DNA binding protein 4 -20.0822
MRPL36 mitochondrial ribosomal protein L36 -20.0666
ZNF416 zinc finger protein 416 -20.0257
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -19.9803
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -19.9525
MIR22HG MIR22 host gene -19.9214
GPKOW G patch domain and KOW motifs -19.9208
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -19.915
PRPF6 pre-mRNA processing factor 6 -19.9029
MRPL9 mitochondrial ribosomal protein L9 -19.8254
USP38 ubiquitin specific peptidase 38 -19.8173
GHITM growth hormone inducible transmembrane protein -19.8034
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -19.6425
PPP1R8 protein phosphatase 1, regulatory subunit 8 -19.5941
ZNF79 zinc finger protein 79 -19.5787
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -19.5715
FH fumarate hydratase -19.5496
RBBP7 retinoblastoma binding protein 7 -19.5391
FAF1 Fas (TNFRSF6) associated factor 1 -19.4624
CAPZB capping protein (actin filament) muscle Z-line, beta -19.4422
POLR1F RNA polymerase I subunit F -19.4422
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -19.4039
MFAP1 microfibrillar-associated protein 1 -19.3127
GLRX5 glutaredoxin 5 -19.2965
ETFA electron-transfer-flavoprotein, alpha polypeptide -19.257
LYRM2 LYR motif containing 2 -19.2308
SF3A3 splicing factor 3a, subunit 3, 60kDa -19.2002
HNRNPK heterogeneous nuclear ribonucleoprotein K -19.2002
COPS5 COP9 signalosome subunit 5 -19.131
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -19.0953
CUL1 cullin 1 -19.0953
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -19.0008
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) -18.9753
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -18.9509
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -18.9216
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -18.8234
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -18.7578
ZNF281 zinc finger protein 281 -18.6762
SDAD1 SDA1 domain containing 1 -18.6721
GOLGA7 golgin A7 -18.6091
KAT5 K(lysine) acetyltransferase 5 -18.5704
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -18.5166
MRPL46 mitochondrial ribosomal protein L46 -18.514
API5 apoptosis inhibitor 5 -18.5137
UQCRC2 ubiquinol-cytochrome c reductase core protein II -18.4233
GCC1 GRIP and coiled-coil domain containing 1 -18.3765
MTOR mechanistic target of rapamycin (serine/threonine kinase) -18.3737
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -18.3679
WDR44 WD repeat domain 44 -18.3664
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -18.2648
CISD1 CDGSH iron sulfur domain 1 -18.2588
TSPYL1 TSPY-like 1 -18.2304
PCCA propionyl CoA carboxylase, alpha polypeptide -18.1941
STOML2 stomatin (EPB72)-like 2 -18.1599
DAZAP2 DAZ associated protein 2 -18.1404
AHCYL1 adenosylhomocysteinase-like 1 -18.1299
STEEP1 STING1 ER exit protein 1 -18.1299
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -18.1299
PDHX pyruvate dehydrogenase complex, component X -18.0813
BLTP2 bridge-like lipid transfer protein family member 2 -18.0813
STAU1 staufen double-stranded RNA binding protein 1 -18.0483
KLHL11 kelch-like family member 11 -18.0393
BRD7 bromodomain containing 7 -18.0355
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -17.9661
TOX4 TOX high mobility group box family member 4 -17.9119
ZNG1B Zn regulated GTPase metalloprotein activator 1B -17.9094
M6PR mannose-6-phosphate receptor (cation dependent) -17.8653
TPR translocated promoter region, nuclear basket protein -17.8488
ZCCHC3 zinc finger, CCHC domain containing 3 -17.8488
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -17.8488
KPNA3 karyopherin alpha 3 (importin alpha 4) -17.8344
ZNF518B zinc finger protein 518B -17.8184
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -17.8184
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 -17.8184
RANBP2 RAN binding protein 2 -17.7045
TRMT5 tRNA methyltransferase 5 -17.7
ASB8 ankyrin repeat and SOCS box containing 8 -17.6972
MED7 mediator complex subunit 7 -17.6864
RNF123 ring finger protein 123 -17.6307
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 -17.6175
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -17.5793
ZNF778 zinc finger protein 778 -17.539
XRN2 5'-3' exoribonuclease 2 -17.5005
CHD8 chromodomain helicase DNA binding protein 8 -17.485
FBXL5 F-box and leucine-rich repeat protein 5 -17.485
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -17.485
FRG1 FSHD region gene 1 -17.485
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) -17.4715
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -17.4271
MED18 mediator complex subunit 18 -17.3845
WASHC5 WASH complex subunit 5 -17.3682
C6ORF47 chromosome 6 open reading frame 47 -17.3554
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -17.3551
EIF3A eukaryotic translation initiation factor 3, subunit A -17.3304
SND1 staphylococcal nuclease and tudor domain containing 1 -17.3189
SNW1 SNW domain containing 1 -17.2701
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -17.259
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -17.2377
NUP133 nucleoporin 133kDa -17.2345
USP34 ubiquitin specific peptidase 34 -17.2031
PURB purine-rich element binding protein B -17.2031
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -17.1446
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -17.1423
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -17.1293
CDC5L cell division cycle 5-like -17.1271
SNRPB2 small nuclear ribonucleoprotein polypeptide B -17.0883
SMC3 structural maintenance of chromosomes 3 -17.0591
FADD Fas (TNFRSF6)-associated via death domain -17.0343
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -17.0335
LINC02615 long intergenic non-protein coding RNA 2615 -17.0209
TFIP11 tuftelin interacting protein 11 -16.9999
ABRAXAS2 abraxas 2, BRISC complex subunit -16.981
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -16.9597
MRFAP1 Morf4 family associated protein 1 -16.92
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -16.9156
RUNDC1 RUN domain containing 1 -16.903
FASTKD2 FAST kinase domains 2 -16.903
ZSWIM1 zinc finger, SWIM-type containing 1 -16.903
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -16.8596
THTPA thiamine triphosphatase -16.8177
MAP10 microtubule-associated protein 10 -16.7751
HBS1L HBS1-like translational GTPase -16.7427
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -16.7426
FBXO9 F-box protein 9 -16.7363
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -16.7206
TNPO3 transportin 3 -16.693
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -16.693
ZNF574 zinc finger protein 574 -16.693
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -16.6737
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component -16.6737
HEATR5A HEAT repeat containing 5A -16.64
TRAPPC2B trafficking protein particle complex 2B -16.5508
IPO7 importin 7 -16.5001
COPA coatomer protein complex, subunit alpha -16.4984
CAND1 cullin-associated and neddylation-dissociated 1 -16.4263
IDE insulin-degrading enzyme -16.3945
GRSF1 G-rich RNA sequence binding factor 1 -16.3938
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -16.3842
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -16.37
MAPKAP1 mitogen-activated protein kinase associated protein 1 -16.3468
RNASEH1 ribonuclease H1 -16.3296
MSH6 mutS homolog 6 -16.3031
DCAF7 DDB1 and CUL4 associated factor 7 -16.277
ZC3H13 zinc finger CCCH-type containing 13 -16.2654
CKAP5 cytoskeleton associated protein 5 -16.2151
UBQLN2 ubiquilin 2 -16.2122
HSDL2 hydroxysteroid dehydrogenase like 2 -16.1867
ZNF613 zinc finger protein 613 -16.1808
SF3B4 splicing factor 3b, subunit 4, 49kDa -16.1271
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -16.1167
PPARA peroxisome proliferator-activated receptor alpha -16.0779
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -16.0291
ATP5F1A ATP synthase F1 subunit alpha -16.0244
PRDX3 peroxiredoxin 3 -16.0244
SMC1A structural maintenance of chromosomes 1A -16.0221
PAIP1 poly(A) binding protein interacting protein 1 -15.9715
ZNF669 zinc finger protein 669 -15.9681