GTEx Heart 20-29 vs 30-39 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

197 genes with high or low expression in GTEx Heart 20-29 vs 30-39 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
NMRK1 nicotinamide riboside kinase 1 4.42159
SYT9-AS1 SYT9 antisense RNA 1 3.08942
ZNF718 zinc finger protein 718 3.08942
PNISR PNN-interacting serine/arginine-rich protein 3.08942
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 3.08942
IFT172 intraflagellar transport 172 3.08942
LUC7L3 LUC7-like 3 (S. cerevisiae) 3.08942
GSTM2 glutathione S-transferase mu 2 (muscle) 3.08942
UPB1 ureidopropionase, beta 3.08942
LINC01460 long intergenic non-protein coding RNA 1460 3.08942
ABHD14A abhydrolase domain containing 14A 3.08942
SMIM5 small integral membrane protein 5 3.08942
C16ORF86 chromosome 16 open reading frame 86 3.08942
ENTPD3-AS1 ENTPD3 antisense RNA 1 3.08942
TMC4 transmembrane channel-like 4 3.08942
TP53TG1 TP53 target 1 (non-protein coding) 3.08942
RXRG retinoid X receptor, gamma 3.08942
SPAG8 sperm associated antigen 8 3.08942
TSPEAR thrombospondin-type laminin G domain and EAR repeats 3.08942
OCEL1 occludin/ELL domain containing 1 3.08942
MAGI2-AS3 MAGI2 antisense RNA 3 3.08942
EOLA2-DT EOLA2 divergent transcript 3.08942
SNHG28 small nucleolar RNA host gene 28 3.08942
RFX3-DT RFX3 divergent transcript 3.08942
MAP3K4-AS1 MAP3K4 antisense RNA 1 3.08942
LY6S-AS1 LY6S antisense RNA 1 3.08942
KDSR-DT KDSR divergent transcript 3.08942
DUT-AS1 DUT antisense RNA 1 3.08942
OTULIN-DT OTULIN divergent transcript 3.08942
HEXD hexosaminidase D 3.08942
ZNF76 zinc finger protein 76 3.08942
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 3.08942
SRSF5 serine/arginine-rich splicing factor 5 3.08942
TSSK3 testis-specific serine kinase 3 3.08942
LINC01273 long intergenic non-protein coding RNA 1273 3.08942
PEX6 peroxisomal biogenesis factor 6 3.08942
IFT27 intraflagellar transport 27 3.08942
ING5 inhibitor of growth family, member 5 3.08942
ZNF630 zinc finger protein 630 3.08942
WDFY3-AS2 WDFY3 antisense RNA 2 3.08942
LINC01852 long intergenic non-protein coding RNA 1852 3.08942
ZBED5-AS1 ZBED5 antisense RNA 1 3.08942
NAV2-AS2 NAV2 antisense RNA 2 3.08942
ISYNA1 inositol-3-phosphate synthase 1 3.08942
LMCD1-AS1 LMCD1 antisense RNA 1 (head to head) 3.08942
SPTBN5 spectrin, beta, non-erythrocytic 5 3.08942
SCOC-AS1 SCOC antisense RNA 1 3.08942
ZNF540 zinc finger protein 540 3.08942
RFX1 regulatory factor X, 1 (influences HLA class II expression) 3.08942
TUBA8 tubulin, alpha 8 3.08942
RPL23AP49 ribosomal protein L23a pseudogene 49 3.08942
GPER1 G protein-coupled estrogen receptor 1 3.08942
LINC00310 long intergenic non-protein coding RNA 310 3.08942
SEC16B SEC16 homolog B (S. cerevisiae) 3.08942
SELENBP1 selenium binding protein 1 3.08942
SHBG sex hormone-binding globulin 3.08942
PPP1R3E protein phosphatase 1, regulatory subunit 3E 3.08942
OAZ2 ornithine decarboxylase antizyme 2 3.08942
EPB41L1 erythrocyte membrane protein band 4.1-like 1 3.08942
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 3.08942
S100A14 S100 calcium binding protein A14 3.08942
TLR9 toll-like receptor 9 3.08499
CT62 cancer/testis antigen 62 3.07969
SMTN smoothelin 3.07969
LPCAT4 lysophosphatidylcholine acyltransferase 4 3.06729
PTCH2 patched 2 3.06729
TSNAXIP1 translin-associated factor X interacting protein 1 3.06729
SPMIP8 sperm microtubule inner protein 8 3.05933
SYCE2 synaptonemal complex central element protein 2 3.05933
FBXW4 F-box and WD repeat domain containing 4 3.05933
MHENCR melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489 3.0527
C2ORF92 chromosome 2 open reading frame 92 3.04868
MSANTD7 Myb/SANT DNA binding domain containing 7 3.04868
ZNF511 zinc finger protein 511 3.04423
EPOR erythropoietin receptor 3.04423
ZKSCAN2-DT ZKSCAN2 divergent transcript 3.04423
CCDC180 coiled-coil domain containing 180 3.04423
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.04423
PROM2 prominin 2 3.04423
ABHD1 abhydrolase domain containing 1 3.04423
TNN tenascin N 3.04423
FAM117A family with sequence similarity 117, member A 3.04423
ZNF594 zinc finger protein 594 3.04423
RANBP3L RAN binding protein 3-like 3.03865
CAPN10 calpain 10 3.03614
PROCA1 protein interacting with cyclin A1 3.03614
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 3.03614
CCDC159 coiled-coil domain containing 159 3.03614
UCKL1 uridine-cytidine kinase 1-like 1 3.03412
HSF4 heat shock transcription factor 4 3.03412
ZNF528-AS1 ZNF528 antisense RNA 1 3.03412
MGMT O-6-methylguanine-DNA methyltransferase 3.03331
BTBD2 BTB (POZ) domain containing 2 3.0331
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 3.02258
CCDC183 coiled-coil domain containing 183 3.02258
TOB1-AS1 TOB1 antisense RNA 1 3.02258
ZNF358 zinc finger protein 358 3.02258
GTF2IRD2B GTF2I repeat domain containing 2B 3.01322
IL15 interleukin 15 3.01322
LOC100506235 uncharacterized LOC100506235 2.99716

decreased expression

Symbol Name Standardized Value
UTP25 UTP25 small subunit processome component -3.08942
C6ORF62 chromosome 6 open reading frame 62 -3.08942
CD164 CD164 molecule, sialomucin -3.08942
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -3.08942
TES testin LIM domain protein -3.08942
CDC42 cell division cycle 42 -3.08942
NT5DC3 5'-nucleotidase domain containing 3 -3.08942
CCT2 chaperonin containing TCP1, subunit 2 (beta) -3.08942
VAMP7 vesicle-associated membrane protein 7 -3.08942
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -3.08942
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -3.08942
AGFG1 ArfGAP with FG repeats 1 -3.08942
MMP24 matrix metallopeptidase 24 (membrane-inserted) -3.08942
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -3.08942
MAP3K9 mitogen-activated protein kinase kinase kinase 9 -3.08942
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.08942
RHOA ras homolog family member A -3.08942
PIGW phosphatidylinositol glycan anchor biosynthesis, class W -3.08942
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -3.08942
MCFD2 multiple coagulation factor deficiency 2 -3.08942
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -3.08942
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -3.08942
ZPR1 ZPR1 zinc finger -3.08942
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -3.08942
ARMC8 armadillo repeat containing 8 -3.08942
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -3.08942
COPA coatomer protein complex, subunit alpha -3.08942
IL1R2 interleukin 1 receptor, type II -3.08942
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -3.08942
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -3.08942
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -3.08942
SRP72 signal recognition particle 72kDa -3.08942
PTPRH protein tyrosine phosphatase, receptor type, H -3.08942
ACOT9 acyl-CoA thioesterase 9 -3.08942
GBE1 glucan (1,4-alpha-), branching enzyme 1 -3.08942
COPB1 coatomer protein complex, subunit beta 1 -3.08942
AAGAB alpha- and gamma-adaptin binding protein -3.08942
MTPN myotrophin -3.08942
TMED2 transmembrane emp24 domain trafficking protein 2 -3.08942
TMED5 transmembrane emp24 protein transport domain containing 5 -3.08942
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -3.08942
RAB5A RAB5A, member RAS oncogene family -3.08942
MYADM myeloid-associated differentiation marker -3.08942
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) -3.08942
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -3.08942
ARCN1 archain 1 -3.08942
TUBA1C tubulin, alpha 1c -3.08942
SLC35F6 solute carrier family 35, member F6 -3.08942
SLC35F5 solute carrier family 35, member F5 -3.08942
GDI2 GDP dissociation inhibitor 2 -3.08942
RAD9B RAD9 homolog B (S. pombe) -3.08942
DHDDS dehydrodolichyl diphosphate synthase -3.08942
CCDC6 coiled-coil domain containing 6 -3.08942
NIFK nucleolar protein interacting with the FHA domain of MKI67 -3.08942
MAP1B microtubule-associated protein 1B -3.08942
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -3.08942
FSTL3 follistatin-like 3 (secreted glycoprotein) -3.08942
RBM8A RNA binding motif protein 8A -3.08942
RIOK3 RIO kinase 3 -3.08942
OXSR1 oxidative stress responsive 1 -3.08435
NSF N-ethylmaleimide-sensitive factor -3.06729
KRT80 keratin 80, type II -3.06729
TUBB3 tubulin, beta 3 class III -3.06729
DLG1 discs, large homolog 1 (Drosophila) -3.06323
TNC tenascin C -3.05933
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -3.0527
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -3.0527
RAB11FIP5 RAB11 family interacting protein 5 (class I) -3.05064
SUCO SUN domain containing ossification factor -3.05028
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -3.05028
ABHD5 abhydrolase domain containing 5 -3.04868
RRAGC Ras-related GTP binding C -3.04423
MARCHF5 membrane associated ring-CH-type finger 5 -3.04423
FCMR Fc fragment of IgM receptor -3.04423
EIF1AX eukaryotic translation initiation factor 1A, X-linked -3.04423
KRAS Kirsten rat sarcoma viral oncogene homolog -3.04423
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -3.04423
MAGT1 magnesium transporter 1 -3.04423
TUBB6 tubulin, beta 6 class V -3.04423
ACBD3 acyl-CoA binding domain containing 3 -3.04423
CENPL centromere protein L -3.04423
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -3.04423
FN1 fibronectin 1 -3.04423
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -3.03614
ATF6 activating transcription factor 6 -3.03614
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -3.03614
SARS1 seryl-tRNA synthetase 1 -3.03412
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -3.03412
SH3GLB1 SH3-domain GRB2-like endophilin B1 -3.02258
SPRED3 sprouty-related, EVH1 domain containing 3 -3.02258
RINT1 RAD50 interactor 1 -3.02258
RHEB Ras homolog enriched in brain -3.02258
SEC31A SEC31 homolog A (S. cerevisiae) -3.02258
TRMT6 tRNA methyltransferase 6 -3.02258
APMAP adipocyte plasma membrane associated protein -3.02258
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -3.01322
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.99716