GTEx Heart 20-29 vs 60-69 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

500 genes with high or low expression in GTEx Heart 20-29 vs 60-69 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
EDA2R ectodysplasin A2 receptor 24.3295
PTCHD4 patched domain containing 4 20.3799
SPATA18 spermatogenesis associated 18 13.52
MIR34AHG MIR34A host gene 11.9261
PCDHB9 protocadherin beta 9 9.52922
LIPH lipase, member H 9.32967
AUTS2 autism susceptibility candidate 2 9.30656
GRAMD1C GRAM domain containing 1C 9.30656
CXCL14 chemokine (C-X-C motif) ligand 14 9.30656
GDF15 growth differentiation factor 15 9.30656
ADCY2 adenylate cyclase 2 (brain) 9.30656
DDB2 damage-specific DNA binding protein 2, 48kDa 9.30656
DUXAP8 double homeobox A pseudogene 8 9.30656
EPOR erythropoietin receptor 9.29047
BMP4 bone morphogenetic protein 4 9.17126
FMO3 flavin containing monooxygenase 3 9.04585
WNT2B wingless-type MMTV integration site family, member 2B 8.94976
ZMAT3 zinc finger, matrin-type 3 8.94976
CPXM2 carboxypeptidase X (M14 family), member 2 8.83622
RNF135 ring finger protein 135 8.65483
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8.65483
TBC1D2B TBC1 domain family, member 2B 8.6212
PHLDA3 pleckstrin homology-like domain, family A, member 3 8.54787
CP ceruloplasmin (ferroxidase) 8.54739
SPDYA speedy/RINGO cell cycle regulator family member A 8.54389
ZNF678 zinc finger protein 678 8.53488
ZNF621 zinc finger protein 621 8.47776
PRELP proline/arginine-rich end leucine-rich repeat protein 8.42359
NXF3 nuclear RNA export factor 3 8.41413
TRIM22 tripartite motif containing 22 8.41413
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 8.39374
LMO3 LIM domain only 3 (rhombotin-like 2) 8.39213
TMEM243 transmembrane protein 243, mitochondrial 8.34523
SPATA6L spermatogenesis associated 6-like 8.30947
SORBS3 sorbin and SH3 domain containing 3 8.30187
ARRDC2 arrestin domain containing 2 8.30052
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 8.29227
LTBP2 latent transforming growth factor beta binding protein 2 8.26296
FAS Fas cell surface death receptor 8.25952
FCHSD1 FCH and double SH3 domains 1 8.22848
TLDC2 TBC/LysM-associated domain containing 2 8.20655
SYCE2 synaptonemal complex central element protein 2 8.19287
CCL28 chemokine (C-C motif) ligand 28 8.19128
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 8.19128
PODNL1 podocan-like 1 8.19128
TTC7A tetratricopeptide repeat domain 7A 8.18671
LINC00968 long intergenic non-protein coding RNA 968 8.17367
KLHL29 kelch-like family member 29 8.17002
XPC xeroderma pigmentosum, complementation group C 8.14311
CA5B carbonic anhydrase VB, mitochondrial 8.14135
SNX33 sorting nexin 33 8.14135
PCNX2 pecanex 2 8.129
TGFB1I1 transforming growth factor beta 1 induced transcript 1 8.129
BMP6 bone morphogenetic protein 6 8.09388
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 8.06041
ETV5 ets variant 5 7.99367
FLT3LG fms-related tyrosine kinase 3 ligand 7.99367
ZNF558 zinc finger protein 558 7.98869
FMNL1 formin-like 1 7.98741
RGL3 ral guanine nucleotide dissociation stimulator-like 3 7.95848
PRICKLE2 prickle homolog 2 (Drosophila) 7.94841
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 7.94603
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 7.94603
CST3 cystatin C 7.92565
COMP cartilage oligomeric matrix protein 7.92372
FRMD4B FERM domain containing 4B 7.90837
NEK5 NIMA-related kinase 5 7.90081
TMEM100 transmembrane protein 100 7.89658
ZNF254 zinc finger protein 254 7.88818
HBB hemoglobin, beta 7.86427
TLR9 toll-like receptor 9 7.86263
XG Xg blood group 7.86118
MHENCR melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489 7.8605
PLSCR4 phospholipid scramblase 4 7.84484
DNASE1L3 deoxyribonuclease I-like 3 7.83664
EVC2 Ellis van Creveld syndrome 2 7.82196
LINC00294 long intergenic non-protein coding RNA 294 7.73596
NADSYN1 NAD synthetase 1 7.73499
CEP164 centrosomal protein 164kDa 7.73499
C2 complement component 2 7.722
CKMT2-AS1 CKMT2 antisense RNA 1 7.69685
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 7.69159
KAZN kazrin, periplakin interacting protein 7.68213
MEI1 meiosis inhibitor 1 7.64953
GHDC GH3 domain containing 7.64022
IDUA iduronidase, alpha-L- 7.63527
LYST lysosomal trafficking regulator 7.6188
COL8A2 collagen, type VIII, alpha 2 7.60281
ACKR2 atypical chemokine receptor 2 7.59985
NOVA1 neuro-oncological ventral antigen 1 7.57437
ANGPTL5 angiopoietin-like 5 7.57294
ARHGAP22 Rho GTPase activating protein 22 7.55501
ZNF136 zinc finger protein 136 7.49625
NPC1L1 NPC1-like 1 7.48593
MRNIP MRN complex interacting protein 7.48529
MAST3 microtubule associated serine/threonine kinase 3 7.48529
CEP126 centrosomal protein 126kDa 7.4497
NLRP1 NLR family, pyrin domain containing 1 7.44422
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 7.4414
LPCAT1 lysophosphatidylcholine acyltransferase 1 7.4377
TUG1 taurine up-regulated 1 (non-protein coding) 7.4377
HAUS7 HAUS augmin-like complex, subunit 7 7.4077
ANKRD13D ankyrin repeat domain 13 family, member D 7.4077
RPH3AL-AS1 RPH3AL antisense RNA 1 7.4077
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 7.38382
CFAP91 cilia and flagella associated protein 91 7.37986
LPAR2 lysophosphatidic acid receptor 2 7.36284
DLEC1 deleted in lung and esophageal cancer 1 7.34208
MAX MYC associated factor X 7.34208
C16ORF89 chromosome 16 open reading frame 89 7.31928
ANKRD10 ankyrin repeat domain 10 7.31926
FAM81B family with sequence similarity 81, member B 7.29438
KEL Kell blood group, metallo-endopeptidase 7.29182
ZNF676 zinc finger protein 676 7.29182
PDIA2 protein disulfide isomerase family A, member 2 7.29006
HOXB2 homeobox B2 7.28968
PRDM8 PR domain containing 8 7.28833
DVL2 dishevelled segment polarity protein 2 7.27883
HBA2 hemoglobin, alpha 2 7.26733
ZNF217 zinc finger protein 217 7.26733
FBXO17 F-box protein 17 7.26733
GMIP GEM interacting protein 7.26733
RBM5 RNA binding motif protein 5 7.24987
RGL4 ral guanine nucleotide dissociation stimulator-like 4 7.24987
UBQLNL ubiquilin-like 7.24987
CLEC2B C-type lectin domain family 2, member B 7.24847
DHRS3 dehydrogenase/reductase (SDR family) member 3 7.24847
CDAN1 codanin 1 7.24177
CREBZF CREB/ATF bZIP transcription factor 7.23227
LPCAT2 lysophosphatidylcholine acyltransferase 2 7.23073
USP35 ubiquitin specific peptidase 35 7.22417
SAP30-DT SAP30 divergent transcript 7.22417
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 7.19274
PKD2 polycystic kidney disease 2 (autosomal dominant) 7.18538
ZNF34 zinc finger protein 34 7.18189
SPATA6 spermatogenesis associated 6 7.15474
KCTD13 potassium channel tetramerization domain containing 13 7.13779
LENG8 leukocyte receptor cluster (LRC) member 8 7.1369
ACHE acetylcholinesterase (Yt blood group) 7.12182
CYRIA CYFIP related Rac1 interactor A 7.11748
PRDM6 PR domain containing 6 7.11255
TSHZ2 teashirt zinc finger homeobox 2 7.11099
SETBP1 SET binding protein 1 7.11077
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 7.11032
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 7.11032
RRN3P2 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2 7.09301
CCDC88B coiled-coil domain containing 88B 7.07904
TBX19 T-box 19 7.07904
FBXL2 F-box and leucine-rich repeat protein 2 7.04504
LUC7L3 LUC7-like 3 (S. cerevisiae) 7.04504
IL17RE interleukin 17 receptor E 7.0344
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 7.02927
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 7.02451
PRR5 proline rich 5 (renal) 7.02451
PAXBP1 PAX3 and PAX7 binding protein 1 7.01121
RBMS3 RNA binding motif, single stranded interacting protein 3 7.00617
NPIPA1 nuclear pore complex interacting protein family, member A1 7.00617
ING5 inhibitor of growth family, member 5 7.00578
BEGAIN brain-enriched guanylate kinase-associated 7.00578
RAB32 RAB32, member RAS oncogene family 6.99931
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 6.98152
POLM polymerase (DNA directed), mu 6.97505
NBR2 neighbor of BRCA1 gene 2 (non-protein coding) 6.97299
ENG endoglin 6.95321
RNF166 ring finger protein 166 6.93495
SCARB1 scavenger receptor class B, member 1 6.9347
ZNF665 zinc finger protein 665 6.9347
GUSB glucuronidase, beta 6.93353
DRAM1 DNA-damage regulated autophagy modulator 1 6.93331
CTC1 CTS telomere maintenance complex component 1 6.92784
HPS4 Hermansky-Pudlak syndrome 4 6.92281
AKNA AT-hook transcription factor 6.91748
XNDC1N XRCC1 N-terminal domain containing 1, N-terminal like 6.91737
SPTBN2 spectrin, beta, non-erythrocytic 2 6.89849
CLK1 CDC-like kinase 1 6.88938
LRRC56 leucine rich repeat containing 56 6.88938
CSF1 colony stimulating factor 1 (macrophage) 6.8891
PTGFR prostaglandin F receptor (FP) 6.8882
LINC00926 long intergenic non-protein coding RNA 926 6.88425
KCNT2 potassium channel, sodium activated subfamily T, member 2 6.88097
CTSK cathepsin K 6.87974
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 6.87526
DNAH1 dynein, axonemal, heavy chain 1 6.8677
CLSTN3 calsyntenin 3 6.86219
RERG RAS-like, estrogen-regulated, growth inhibitor 6.86131
HBA1 hemoglobin, alpha 1 6.85653
TPBG trophoblast glycoprotein 6.85302
PTPN9 protein tyrosine phosphatase, non-receptor type 9 6.85256
DSE dermatan sulfate epimerase 6.81688
PHF8 PHD finger protein 8 6.81314
CEROX1 cytoplasmic endogenous regulator of oxidative phosphorylation 1 6.81066
PRSS53 protease, serine, 53 6.80908
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 6.80697
RHBDD2 rhomboid domain containing 2 6.8067
GRB10 growth factor receptor-bound protein 10 6.80545
DYNLT2 dynein light chain Tctex-type 2 6.80374
GBP2 guanylate binding protein 2, interferon-inducible 6.7994
CDA cytidine deaminase 6.79834
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 6.78706
SOCS2-AS1 SOCS2 antisense RNA 1 6.78582
DPH7 diphthamide biosynthesis 7 6.78135
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 6.77918
AKT3 v-akt murine thymoma viral oncogene homolog 3 6.77402
LINC00506 long intergenic non-protein coding RNA 506 6.77402
NPHP3 nephronophthisis 3 (adolescent) 6.76976
MYO1D myosin ID 6.76976
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 6.76976
PFKL phosphofructokinase, liver 6.75666
SPIN4 spindlin family, member 4 6.74952
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 6.74952
CLEC4A C-type lectin domain family 4, member A 6.74952
BORCS8-MEF2B BORCS8-MEF2B readthrough 6.74952
ANKRD49 ankyrin repeat domain 49 6.74952
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 6.74952
PCDHB4 protocadherin beta 4 6.7494
BOC BOC cell adhesion associated, oncogene regulated 6.74238
NSD3 nuclear receptor binding SET domain protein 3 6.72941
TRAF5 TNF receptor-associated factor 5 6.72118
PABPC1L poly(A) binding protein, cytoplasmic 1-like 6.71824
SAXO4 stabilizer of axonemal microtubules 4 6.71769
VWCE von Willebrand factor C and EGF domains 6.70437
HOXB-AS1 HOXB cluster antisense RNA 1 6.70424
HTRA1 HtrA serine peptidase 1 6.70301
ENO2 enolase 2 (gamma, neuronal) 6.70301
LINC00304 long intergenic non-protein coding RNA 304 6.70301
SRRM1 serine/arginine repetitive matrix 1 6.70301
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 6.69974
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 6.69858
MEGF6 multiple EGF-like-domains 6 6.69858
FRZB frizzled-related protein 6.69741
DOCK11 dedicator of cytokinesis 11 6.69692
SPRY4 sprouty homolog 4 (Drosophila) 6.69118
IFITM10 interferon induced transmembrane protein 10 6.68514
KLRD1 killer cell lectin-like receptor subfamily D, member 1 6.67983
CRACR2A calcium release activated channel regulator 2A 6.67852
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 6.67852
TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae) 6.6714
RBM11 RNA binding motif protein 11 6.6714
MNMIP1 manchette microtubule inner protein 1 6.66916
ARGLU1 arginine and glutamate rich 1 6.65954
PDLIM2 PDZ and LIM domain 2 (mystique) 6.65949
SLC16A4 solute carrier family 16, member 4 6.65893
LOC339260 uncharacterized LOC339260 6.65387
MID2 midline 2 6.63958
IL2RG interleukin 2 receptor, gamma 6.62614
ATP10D ATPase, class V, type 10D 6.61288
NECAP2 NECAP endocytosis associated 2 6.61288
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 6.61288
LZTS2 leucine zipper, putative tumor suppressor 2 6.60443
GAREM2 GRB2 associated regulator of MAPK1 subtype 2 6.60345

decreased expression

Symbol Name Standardized Value
TUSC3 tumor suppressor candidate 3 -11.2598
CALM3 calmodulin 3 (phosphorylase kinase, delta) -10.4609
MRPL15 mitochondrial ribosomal protein L15 -10.4569
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -9.85393
ATP5PB ATP synthase peripheral stalk-membrane subunit b -9.63264
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -9.60228
MRPS22 mitochondrial ribosomal protein S22 -9.60228
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -9.60228
ADSL adenylosuccinate lyase -9.60228
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -9.60228
MRPS28 mitochondrial ribosomal protein S28 -9.52922
DAP3 death associated protein 3 -9.52922
FH fumarate hydratase -9.52922
HSPA9 heat shock 70kDa protein 9 (mortalin) -9.32967
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -9.32967
SSBP1 single-stranded DNA binding protein 1, mitochondrial -9.32967
ATP5F1B ATP synthase F1 subunit beta -9.32967
IMMT inner membrane protein, mitochondrial -9.30656
MRPS10 mitochondrial ribosomal protein S10 -9.30656
CFL2 cofilin 2 (muscle) -9.30656
KLHL41 kelch-like family member 41 -9.30656
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -9.30656
MRPS18C mitochondrial ribosomal protein S18C -9.30656
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -9.30656
UQCRC2 ubiquinol-cytochrome c reductase core protein II -9.30656
DLD dihydrolipoamide dehydrogenase -9.30656
COPS7A COP9 signalosome subunit 7A -9.30656
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -9.30656
EIF3L eukaryotic translation initiation factor 3, subunit L -9.30656
PGM1 phosphoglucomutase 1 -9.30656
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -9.30656
ATXN10 ataxin 10 -9.30656
WDR77 WD repeat domain 77 -9.30656
HSPB8 heat shock 22kDa protein 8 -9.30656
CSNK2A1 casein kinase 2, alpha 1 polypeptide -9.30656
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -9.30656
UBE2A ubiquitin-conjugating enzyme E2A -9.30656
CCT8 chaperonin containing TCP1, subunit 8 (theta) -9.30656
VCP valosin containing protein -9.30656
CS citrate synthase -9.30656
TSLIG3A tRNA splicing ligase complex subunit 3A -9.30656
PPIF peptidylprolyl isomerase F -9.30656
VDAC2 voltage-dependent anion channel 2 -9.30656
PHB1 prohibitin 1 -9.30656
PFN2 profilin 2 -9.30656
GYG1 glycogenin 1 -9.30656
ATP5F1C ATP synthase F1 subunit gamma -9.30656
GHITM growth hormone inducible transmembrane protein -9.30656
MTCH2 mitochondrial carrier 2 -9.30656
STRAP serine/threonine kinase receptor associated protein -9.30656
ATP5MC3 ATP synthase membrane subunit c locus 3 -9.30656
PDHB pyruvate dehydrogenase (lipoamide) beta -9.30656
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -9.30656
MRFAP1 Morf4 family associated protein 1 -9.27955
MDH1 malate dehydrogenase 1, NAD (soluble) -9.24568
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -9.1997
GOT1 glutamic-oxaloacetic transaminase 1, soluble -9.17126
NOA1 nitric oxide associated 1 -9.17126
PRDX3 peroxiredoxin 3 -9.17126
VDAC1 voltage-dependent anion channel 1 -9.17126
CYCS cytochrome c, somatic -9.17126
MRPS35 mitochondrial ribosomal protein S35 -9.15862
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -9.15862
MRPL44 mitochondrial ribosomal protein L44 -9.15862
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -9.15829
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -9.09837
MRPS18B mitochondrial ribosomal protein S18B -9.09334
UGP2 UDP-glucose pyrophosphorylase 2 -9.09108
PREP prolyl endopeptidase -9.07244
RBBP7 retinoblastoma binding protein 7 -9.0638
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -9.05541
TRAP1 TNF receptor-associated protein 1 -9.05541
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -9.05541
TOMM70 translocase of outer mitochondrial membrane 70 -9.04585
CCT7 chaperonin containing TCP1, subunit 7 (eta) -9.04585
COPS3 COP9 signalosome subunit 3 -9.04585
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -9.04585
GLRX3 glutaredoxin 3 -9.04585
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -9.04514
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -9.01556
PDHX pyruvate dehydrogenase complex, component X -9.01556
FKBP3 FK506 binding protein 3, 25kDa -9.00584
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -9.00584
MRPS16 mitochondrial ribosomal protein S16 -9.00474
ELOC elongin C -9.00418
KIFBP kinesin family binding protein -8.98863
ACTN2 actinin, alpha 2 -8.9366
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit -8.92261
PARP1 poly (ADP-ribose) polymerase 1 -8.92261
CXADR coxsackie virus and adenovirus receptor -8.92261
DRC3 dynein regulatory complex subunit 3 -8.89418
BZW2 basic leucine zipper and W2 domains 2 -8.8912
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) -8.87943
MAIP1 matrix AAA peptidase interacting protein 1 -8.87943
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -8.87722
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -8.78146
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -8.77173
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -8.76809
MAD2L1BP MAD2L1 binding protein -8.74055
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -8.73949
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -8.71366
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -8.70121
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -8.6957
MRPL30 mitochondrial ribosomal protein L30 -8.6957
PDLIM5 PDZ and LIM domain 5 -8.66704
HINT1 histidine triad nucleotide binding protein 1 -8.66704
CAMK2D calcium/calmodulin-dependent protein kinase II delta -8.65491
MRPL39 mitochondrial ribosomal protein L39 -8.65483
ICA1 islet cell autoantigen 1, 69kDa -8.65483
MICU2 mitochondrial calcium uptake 2 -8.65483
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -8.65483
UQCRH ubiquinol-cytochrome c reductase hinge protein -8.65308
MRPL46 mitochondrial ribosomal protein L46 -8.649
MRPS9 mitochondrial ribosomal protein S9 -8.6417
HBS1L HBS1-like translational GTPase -8.6264
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -8.6264
DCTN2 dynactin 2 (p50) -8.6264
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -8.60927
REXO2 RNA exonuclease 2 -8.60742
THSD4 thrombospondin, type I, domain containing 4 -8.60742
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -8.60742
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -8.60742
FASTKD2 FAST kinase domains 2 -8.60742
TYRP1 tyrosinase-related protein 1 -8.60742
MRPL35 mitochondrial ribosomal protein L35 -8.60585
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -8.60585
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -8.60585
NIBAN1 niban apoptosis regulator 1 -8.60438
COPS5 COP9 signalosome subunit 5 -8.58568
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -8.58401
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -8.5601
ETFA electron-transfer-flavoprotein, alpha polypeptide -8.51924
TSFM Ts translation elongation factor, mitochondrial -8.51924
STOML2 stomatin (EPB72)-like 2 -8.48576
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -8.47511
OLA1 Obg-like ATPase 1 -8.45866
SPRYD4 SPRY domain containing 4 -8.45866
ETNPPL ethanolamine-phosphate phospho-lyase -8.45866
ANXA7 annexin A7 -8.45866
EIF3M eukaryotic translation initiation factor 3, subunit M -8.4525
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) -8.4525
GRSF1 G-rich RNA sequence binding factor 1 -8.44512
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -8.43356
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor -8.43356
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -8.42359
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 -8.42359
RTCA RNA 3'-terminal phosphate cyclase -8.42359
MALSU1 mitochondrial assembly of ribosomal large subunit 1 -8.42359
MACROH2A2 macroH2A.2 histone -8.42359
VDAC3 voltage-dependent anion channel 3 -8.42359
EMC4 ER membrane protein complex subunit 4 -8.42359
MYPN myopalladin -8.42359
CCDC43 coiled-coil domain containing 43 -8.42359
NOAZFP nucleolar atypical zinc finger -8.41413
CDC42 cell division cycle 42 -8.40489
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -8.40489
BOLA2 bolA family member 2 -8.39215
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -8.39213
CASQ2 calsequestrin 2 (cardiac muscle) -8.39213
LMOD3 leiomodin 3 (fetal) -8.39213
USP10 ubiquitin specific peptidase 10 -8.39213
CISD1 CDGSH iron sulfur domain 1 -8.39213
EMC3 ER membrane protein complex subunit 3 -8.39213
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 -8.38762
NOP9 NOP9 nucleolar protein -8.38606
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -8.38517
NARS1 asparaginyl-tRNA synthetase 1 -8.36398
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 -8.36398
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -8.35219
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -8.34928
GSPT1 G1 to S phase transition 1 -8.34823
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -8.34823
TECRL trans-2,3-enoyl-CoA reductase-like -8.34823
LYPLA1 lysophospholipase I -8.34523
PLAA phospholipase A2-activating protein -8.34523
SAMM50 SAMM50 sorting and assembly machinery component -8.34068
APEH acylaminoacyl-peptide hydrolase -8.33435
BVES blood vessel epicardial substance -8.33435
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -8.31006
SRRD SRR1 domain containing -8.30947
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -8.30947
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -8.30187
COPS4 COP9 signalosome subunit 4 -8.30187
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -8.30052
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -8.30052
ALAS1 5'-aminolevulinate synthase 1 -8.3001
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -8.3001
HSPA4 heat shock 70kDa protein 4 -8.3001
DRG1 developmentally regulated GTP binding protein 1 -8.3001
FAM120A family with sequence similarity 120A -8.29325
GSK3B glycogen synthase kinase 3 beta -8.27314
FXR1 fragile X mental retardation, autosomal homolog 1 -8.27314
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 -8.26783
AKAP6 A kinase (PRKA) anchor protein 6 -8.26783
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -8.26783
AURKA aurora kinase A -8.26783
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -8.26783
MFAP1 microfibrillar-associated protein 1 -8.26296
TSPYL1 TSPY-like 1 -8.25952
PUDP pseudouridine 5'-phosphatase -8.25952
MRPL45 mitochondrial ribosomal protein L45 -8.22852
TUFM Tu translation elongation factor, mitochondrial -8.20768
GTPBP8 GTP-binding protein 8 (putative) -8.20768
GFM1 G elongation factor, mitochondrial 1 -8.20768
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -8.20655
SMPX small muscle protein, X-linked -8.1962
TP53INP2 tumor protein p53 inducible nuclear protein 2 -8.19287
ANAPC13 anaphase promoting complex subunit 13 -8.19287
RTRAF RNA transcription, translation and transport factor -8.19287
WSB2 WD repeat and SOCS box containing 2 -8.19287
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -8.19128
PFKM phosphofructokinase, muscle -8.19128
MCTS1 malignant T cell amplified sequence 1 -8.18671
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -8.17367
FAF1 Fas (TNFRSF6) associated factor 1 -8.17367
LDHB lactate dehydrogenase B -8.17367
KLHL34 kelch-like family member 34 -8.17367
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -8.17189
ATP5F1A ATP synthase F1 subunit alpha -8.17189
MRPL47 mitochondrial ribosomal protein L47 -8.17189
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -8.17002
CAVIN4 caveolae associated protein 4 -8.17002
SUCLG1 succinate-CoA ligase, alpha subunit -8.17002
NCOA4 nuclear receptor coactivator 4 -8.17002
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -8.17002
DDB1 damage-specific DNA binding protein 1, 127kDa -8.17002
XIRP2 xin actin binding repeat containing 2 -8.17002
MRPS30 mitochondrial ribosomal protein S30 -8.17002
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -8.16795
PAIP1 poly(A) binding protein interacting protein 1 -8.16307
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -8.14311
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -8.14135
DIABLO diablo, IAP-binding mitochondrial protein -8.14135
LRPPRC leucine-rich pentatricopeptide repeat containing -8.14135
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -8.11732
METAP1 methionyl aminopeptidase 1 -8.11732
C1QBP complement component 1, q subcomponent binding protein -8.10907
COPZ1 coatomer protein complex, subunit zeta 1 -8.10143
DLAT dihydrolipoamide S-acetyltransferase -8.09388
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -8.09388
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -8.06217
ACOT13 acyl-CoA thioesterase 13 -8.06041
RAB5B RAB5B, member RAS oncogene family -8.06041
HCCS holocytochrome c synthase -8.05394
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -8.04722
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -8.03784
SEPHS2 selenophosphate synthetase 2 -8.03784
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -8.03784
EIF3J eukaryotic translation initiation factor 3, subunit J -8.03784
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -8.02427