GTEx Heart 20-29 vs 70-79 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

500 genes with high or low expression in GTEx Heart 20-29 vs 70-79 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
EDA2R ectodysplasin A2 receptor 21.6308
PTCHD4 patched domain containing 4 17.8629
SPATA18 spermatogenesis associated 18 15.8729
DDB2 damage-specific DNA binding protein 2, 48kDa 15.8729
MIR34AHG MIR34A host gene 12.1425
FMO3 flavin containing monooxygenase 3 11.6416
PHLDA3 pleckstrin homology-like domain, family A, member 3 11.6416
FCHSD1 FCH and double SH3 domains 1 11.2015
CPXM2 carboxypeptidase X (M14 family), member 2 11.1762
DUXAP8 double homeobox A pseudogene 8 10.9293
GDF15 growth differentiation factor 15 10.8319
ENO2 enolase 2 (gamma, neuronal) 10.2864
WNT2B wingless-type MMTV integration site family, member 2B 10.2744
SCARB1 scavenger receptor class B, member 1 9.65831
IDUA iduronidase, alpha-L- 9.6312
HTRA1 HtrA serine peptidase 1 9.60701
TRIM22 tripartite motif containing 22 9.52722
LTBP2 latent transforming growth factor beta binding protein 2 9.37913
SPATA6L spermatogenesis associated 6-like 9.25011
IRF3 interferon regulatory factor 3 9.2188
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 9.2188
EPOR erythropoietin receptor 9.06303
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 9.03158
CLSTN3 calsyntenin 3 8.986
DVL2 dishevelled segment polarity protein 2 8.95836
MRNIP MRN complex interacting protein 8.87287
MYO15B myosin XVB 8.71604
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 8.70476
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 8.70476
TMEM91 transmembrane protein 91 8.70476
FBF1 Fas (TNFRSF6) binding factor 1 8.70476
TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 8.70476
MST1 macrophage stimulating 1 8.70476
SORBS3 sorbin and SH3 domain containing 3 8.70476
TMEM54 transmembrane protein 54 8.70476
RBP5 retinol binding protein 5, cellular 8.70476
NLRP1 NLR family, pyrin domain containing 1 8.685
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 8.64255
PDIA2 protein disulfide isomerase family A, member 2 8.63445
CEROX1 cytoplasmic endogenous regulator of oxidative phosphorylation 1 8.61753
NOX4 NADPH oxidase 4 8.59031
CDK5RAP3 CDK5 regulatory subunit associated protein 3 8.59031
CDK3 cyclin-dependent kinase 3 8.54286
RHPN1 rhophilin, Rho GTPase binding protein 1 8.4988
LIPH lipase, member H 8.48992
GRAMD1C GRAM domain containing 1C 8.472
NME3 NME/NM23 nucleoside diphosphate kinase 3 8.45044
DNM1 dynamin 1 8.45023
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 8.44656
INVS inversin 8.44472
DNAH1 dynein, axonemal, heavy chain 1 8.44472
HPS4 Hermansky-Pudlak syndrome 4 8.44472
NADSYN1 NAD synthetase 1 8.44472
RPH3AL-AS1 RPH3AL antisense RNA 1 8.44472
ZNF225-AS1 ZNF225 and ZNF224 antisense RNA 1 8.44281
LZTS2 leucine zipper, putative tumor suppressor 2 8.44267
SLC26A11 solute carrier family 26 (anion exchanger), member 11 8.41243
RGS11 regulator of G-protein signaling 11 8.41243
AZIN2 antizyme inhibitor 2 8.39324
KAT2A K(lysine) acetyltransferase 2A 8.38142
ZNF506 zinc finger protein 506 8.36187
PHLDB3 pleckstrin homology-like domain, family B, member 3 8.35769
ANKRD13D ankyrin repeat domain 13 family, member D 8.35769
LEMD2 LEM domain containing 2 8.33512
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 8.32771
ZNF83 zinc finger protein 83 8.32638
NUPR1 nuclear protein, transcriptional regulator, 1 8.31767
FER1L4 fer-1-like family member 4, pseudogene (functional) 8.31767
CCNL2 cyclin L2 8.29438
SYCE2 synaptonemal complex central element protein 2 8.27266
SLC6A12-AS1 SLC6A12 antisense RNA 1 8.26676
NBL1 neuroblastoma 1, DAN family BMP antagonist 8.25845
RBM5 RNA binding motif protein 5 8.25845
FLT3LG fms-related tyrosine kinase 3 ligand 8.25306
BBLN bublin coiled coil protein 8.24839
C2 complement component 2 8.21917
EPS8L2 EPS8-like 2 8.19827
PRSS53 protease, serine, 53 8.19827
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 8.19362
WDR27 WD repeat domain 27 8.18136
BMP4 bone morphogenetic protein 4 8.17221
SYNGAP1 synaptic Ras GTPase activating protein 1 8.15085
ANKMY1 ankyrin repeat and MYND domain containing 1 8.14618
CDRT4 CMT1A duplicated region transcript 4 8.13921
GHDC GH3 domain containing 8.13921
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 8.13593
ARSA arylsulfatase A 8.11701
RGL3 ral guanine nucleotide dissociation stimulator-like 3 8.09657
PCDHB7 protocadherin beta 7 8.07957
LRRC75B leucine rich repeat containing 75B 8.07892
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 8.07892
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 8.07892
APOC1 apolipoprotein C-I 8.07892
ING5 inhibitor of growth family, member 5 8.06801
MDK midkine (neurite growth-promoting factor 2) 8.06801
SNORC secondary ossification center associated regulator of chondrocyte maturation 8.06801
ARHGAP22 Rho GTPase activating protein 22 8.04813
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 8.03145
ALOX12-AS1 ALOX12 antisense RNA 1 8.01307
TTLL3 tubulin tyrosine ligase-like family member 3 8.01307
C2ORF92 chromosome 2 open reading frame 92 8.01307
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 8.01253
RAB24 RAB24, member RAS oncogene family 8.01253
RABL2A RAB, member of RAS oncogene family-like 2A 8.01011
EBF4 early B-cell factor 4 8.01011
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 7.98923
LRP1 low density lipoprotein receptor-related protein 1 7.94999
LMO3 LIM domain only 3 (rhombotin-like 2) 7.94797
TBC1D2B TBC1 domain family, member 2B 7.91542
INF2 inverted formin, FH2 and WH2 domain containing 7.90573
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 7.86191
SOCS2-AS1 SOCS2 antisense RNA 1 7.83576
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 7.83576
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 7.8351
SGSH N-sulfoglucosamine sulfohydrolase 7.82475
KSR1 kinase suppressor of ras 1 7.82475
IL15 interleukin 15 7.82475
NLGN2 neuroligin 2 7.82064
LINC02145 long intergenic non-protein coding RNA 2145 7.81162
MYL5 myosin, light chain 5, regulatory 7.76013
PCNX2 pecanex 2 7.75296
ANXA2R-AS1 ANXA2R antisense RNA 1 7.74189
ARHGAP33 Rho GTPase activating protein 33 7.74012
AKNA AT-hook transcription factor 7.71488
SSH3 slingshot protein phosphatase 3 7.71345
IFT20 intraflagellar transport 20 7.70608
PFKL phosphofructokinase, liver 7.69691
PHF1 PHD finger protein 1 7.69648
CYP1B1-AS1 CYP1B1 antisense RNA 1 7.68681
JPX JPX transcript, XIST activator (non-protein coding) 7.68277
LENG8 leukocyte receptor cluster (LRC) member 8 7.68113
MXRA8 matrix-remodelling associated 8 7.68113
NEIL1 nei endonuclease VIII-like 1 (E. coli) 7.68113
ZMAT3 zinc finger, matrin-type 3 7.66892
DRD4 dopamine receptor D4 7.65939
C1RL-AS1 C1RL antisense RNA 1 7.65732
CXCL14 chemokine (C-X-C motif) ligand 14 7.65732
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 7.65732
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 7.65732
FBXL8 F-box and leucine-rich repeat protein 8 7.64049
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 7.63969
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 7.60534
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 7.60534
USP35 ubiquitin specific peptidase 35 7.60534
ZNF276 zinc finger protein 276 7.60534
FIRRE firre intergenic repeating RNA element 7.60389
LOC107985433 putative uncharacterized protein LOC401522 7.59203
GGT1 gamma-glutamyltransferase 1 7.58392
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 7.5798
SLC38A10 solute carrier family 38, member 10 7.5798
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 7.57783
SNX33 sorting nexin 33 7.57111
CCL28 chemokine (C-C motif) ligand 28 7.56392
ZDHHC1 zinc finger, DHHC-type containing 1 7.55211
GNLY granulysin 7.55044
KCTD13 potassium channel tetramerization domain containing 13 7.55044
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 7.52961
SH3GLB2 SH3-domain GRB2-like endophilin B2 7.51195
GATAD1 GATA zinc finger domain containing 1 7.5119
FAM193B family with sequence similarity 193, member B 7.5119
LMF2 lipase maturation factor 2 7.51031
MBOAT7 membrane bound O-acyltransferase domain containing 7 7.5059
MFF-DT MFF divergent transcript 7.5059
TBX19 T-box 19 7.5059
RNF166 ring finger protein 166 7.5059
ACKR2 atypical chemokine receptor 2 7.5059
TTC7A tetratricopeptide repeat domain 7A 7.50471
TGFB1 transforming growth factor, beta 1 7.46602
CCDC85B coiled-coil domain containing 85B 7.46087
DDAH2 dimethylarginine dimethylaminohydrolase 2 7.46072
ETV5 ets variant 5 7.45634
TMEM255B transmembrane protein 255B 7.45413
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 7.44804
LRP3 low density lipoprotein receptor-related protein 3 7.44804
CP ceruloplasmin (ferroxidase) 7.44644
TBC1D10C TBC1 domain family, member 10C 7.44099
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 7.43152
CEP164 centrosomal protein 164kDa 7.42864
DNASE1L3 deoxyribonuclease I-like 3 7.41698
PDLIM2 PDZ and LIM domain 2 (mystique) 7.40058
RRN3P2 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2 7.39587
CFAP91 cilia and flagella associated protein 91 7.39587
HOXB-AS1 HOXB cluster antisense RNA 1 7.39587
NBEAP2 neurobeachin pseudogene 2 7.39587
XG Xg blood group 7.38934
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 7.3891
PLXNB2 plexin B2 7.37627
ESPN espin 7.3725
PCDHB9 protocadherin beta 9 7.37064
PALM paralemmin 7.36452
PARD6G-AS1 PARD6G antisense RNA 1 7.36452
CCDC78 coiled-coil domain containing 78 7.36452
LPCAT1 lysophosphatidylcholine acyltransferase 1 7.36001
SGSM2 small G protein signaling modulator 2 7.35764
ZNF117 zinc finger protein 117 7.35764
PCED1A PC-esterase domain containing 1A 7.35764
HES7 hes family bHLH transcription factor 7 7.34529
COL8A2 collagen, type VIII, alpha 2 7.34164
BBC3 BCL2 binding component 3 7.34081
HAUS7 HAUS augmin-like complex, subunit 7 7.31212
NPHP3 nephronophthisis 3 (adolescent) 7.31212
NPDC1 neural proliferation, differentiation and control, 1 7.30577
POFUT2 protein O-fucosyltransferase 2 7.30571
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 7.30073
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 7.29447
MNMIP1 manchette microtubule inner protein 1 7.29447
EXOC3L4 exocyst complex component 3-like 4 7.29447
CSF3R colony stimulating factor 3 receptor (granulocyte) 7.29313
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 7.29313
MZF1 myeloid zinc finger 1 7.28123
PLCG1 phospholipase C, gamma 1 7.28107
P3H3 prolyl 3-hydroxylase 3 7.28107
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 7.27431
NPHP4 nephronophthisis 4 7.27431
BOC BOC cell adhesion associated, oncogene regulated 7.27431
CDK9 cyclin-dependent kinase 9 7.25264
ZDHHC8 zinc finger, DHHC-type containing 8 7.24944
LINC00632 long intergenic non-protein coding RNA 632 7.24944
ZNF160 zinc finger protein 160 7.23347
HEIH hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA 7.22141
POU6F1 POU class 6 homeobox 1 7.21752
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 7.2151
LINC01176 long intergenic non-protein coding RNA 1176 7.21161
ZMIZ1-AS1 ZMIZ1 antisense RNA 1 7.20888
CDAN1 codanin 1 7.20888
C1RL complement component 1, r subcomponent-like 7.1998
WBP1 WW domain binding protein 1 7.19503
DXO decapping exoribonuclease 7.19503
CCNG2 cyclin G2 7.19493
SPTBN2 spectrin, beta, non-erythrocytic 2 7.18604
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 7.18369
FMNL1 formin-like 1 7.17505
WDR90 WD repeat domain 90 7.16659
NPIPB11 nuclear pore complex interacting protein family, member B11 7.1631
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 7.15319
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 7.15319
BRAT1 BRCA1-associated ATM activator 1 7.14228
RHBDD2 rhomboid domain containing 2 7.13727
LINC01426 long intergenic non-protein coding RNA 1426 7.13727
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 7.11736
COMP cartilage oligomeric matrix protein 7.11736
MINDY4 MINDY lysine 48 deubiquitinase 4 7.10825
PLPP5 phospholipid phosphatase 5 7.10224
CTSK cathepsin K 7.09345
FAM229A family with sequence similarity 229, member A 7.09153
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 7.0885
NRBP2 nuclear receptor binding protein 2 7.08472
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 7.08467
CA5B carbonic anhydrase VB, mitochondrial 7.08383
ANKRD10 ankyrin repeat domain 10 7.07462

decreased expression

Symbol Name Standardized Value
TSLIG3B tRNA splicing ligase complex subunit 3B -11.1762
ISCA1 iron-sulfur cluster assembly 1 -10.7755
MOB4 MOB family member 4, phocein -10.4918
MRPS35 mitochondrial ribosomal protein S35 -10.2371
MRPS18C mitochondrial ribosomal protein S18C -9.98496
MAP2K4 mitogen-activated protein kinase kinase 4 -9.6312
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -9.60704
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -9.60704
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -9.60701
MTCH2 mitochondrial carrier 2 -9.60701
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -9.60701
TOMM70 translocase of outer mitochondrial membrane 70 -9.40611
MRPS22 mitochondrial ribosomal protein S22 -9.40611
CYCS cytochrome c, somatic -9.37913
MRPL1 mitochondrial ribosomal protein L1 -9.37913
VTA1 vesicle (multivesicular body) trafficking 1 -9.37913
GRSF1 G-rich RNA sequence binding factor 1 -9.31228
LYPLA1 lysophospholipase I -9.31228
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -9.31228
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -9.31228
GSK3B glycogen synthase kinase 3 beta -9.25011
TUSC3 tumor suppressor candidate 3 -9.2188
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -9.2188
MRPL35 mitochondrial ribosomal protein L35 -9.2188
MTMR9 myotubularin related protein 9 -9.21236
PEX13 peroxisomal biogenesis factor 13 -9.168
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) -9.11255
ZNF518B zinc finger protein 518B -9.0879
GFM1 G elongation factor, mitochondrial 1 -9.00084
LACTB2 lactamase, beta 2 -8.98898
MRPS30 mitochondrial ribosomal protein S30 -8.98898
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -8.98898
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -8.98898
HBS1L HBS1-like translational GTPase -8.98898
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -8.98765
RAB2A RAB2A, member RAS oncogene family -8.96403
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -8.95836
ELOC elongin C -8.95836
SLC38A1 solute carrier family 38, member 1 -8.90772
MRPL15 mitochondrial ribosomal protein L15 -8.87287
MICU2 mitochondrial calcium uptake 2 -8.87287
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -8.84104
ATP5PB ATP synthase peripheral stalk-membrane subunit b -8.84104
ANAPC13 anaphase promoting complex subunit 13 -8.83818
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -8.81383
FASTKD2 FAST kinase domains 2 -8.78476
MAIP1 matrix AAA peptidase interacting protein 1 -8.76467
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -8.76467
HSPA9 heat shock 70kDa protein 9 (mortalin) -8.7343
LRPPRC leucine-rich pentatricopeptide repeat containing -8.71807
PRDX3 peroxiredoxin 3 -8.71604
FASTKD5 FAST kinase domains 5 -8.71604
CALM2 calmodulin 2 (phosphorylase kinase, delta) -8.71604
RNF14 ring finger protein 14 -8.71604
VBP1 von Hippel-Lindau binding protein 1 -8.71604
MRPS28 mitochondrial ribosomal protein S28 -8.71604
UBE2A ubiquitin-conjugating enzyme E2A -8.70636
ARL8B ADP-ribosylation factor-like 8B -8.70476
ATXN7L3B ataxin 7-like 3B -8.70476
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -8.70476
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -8.70476
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -8.70476
COPS3 COP9 signalosome subunit 3 -8.70476
FAM168B family with sequence similarity 168, member B -8.70476
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -8.70476
PPIF peptidylprolyl isomerase F -8.70476
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -8.70476
FDX1 ferredoxin 1 -8.70476
RAB10 RAB10, member RAS oncogene family -8.70476
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -8.70476
AMD1 adenosylmethionine decarboxylase 1 -8.70476
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -8.70476
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -8.70476
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -8.70476
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -8.70476
NCOA4 nuclear receptor coactivator 4 -8.70476
HIGD1A HIG1 hypoxia inducible domain family, member 1A -8.70476
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -8.70476
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) -8.70476
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -8.70476
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -8.70476
MRPL44 mitochondrial ribosomal protein L44 -8.70476
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -8.70476
NIBAN1 niban apoptosis regulator 1 -8.70476
OPA1 optic atrophy 1 (autosomal dominant) -8.70476
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -8.70476
ETNPPL ethanolamine-phosphate phospho-lyase -8.685
TXNL1 thioredoxin-like 1 -8.685
NARS1 asparaginyl-tRNA synthetase 1 -8.685
PDE3A phosphodiesterase 3A, cGMP-inhibited -8.685
PTDSS1 phosphatidylserine synthase 1 -8.65433
DLD dihydrolipoamide dehydrogenase -8.64255
TSFM Ts translation elongation factor, mitochondrial -8.64255
COPS5 COP9 signalosome subunit 5 -8.64255
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -8.64255
TFB2M transcription factor B2, mitochondrial -8.64255
CALM3 calmodulin 3 (phosphorylase kinase, delta) -8.64255
MRPS16 mitochondrial ribosomal protein S16 -8.64255
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -8.60791
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma -8.59031
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -8.58815
GHITM growth hormone inducible transmembrane protein -8.54885
ATP5MC3 ATP synthase membrane subunit c locus 3 -8.54885
MRPS9 mitochondrial ribosomal protein S9 -8.52948
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -8.52948
MRPL3 mitochondrial ribosomal protein L3 -8.51172
STRAP serine/threonine kinase receptor associated protein -8.50352
CISD1 CDGSH iron sulfur domain 1 -8.50352
MTX2 metaxin 2 -8.49967
SMIM13 small integral membrane protein 13 -8.49097
KIFBP kinesin family binding protein -8.48992
AURKA aurora kinase A -8.472
UBE2N ubiquitin-conjugating enzyme E2N -8.472
CXADR coxsackie virus and adenovirus receptor -8.472
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -8.46886
APOOL apolipoprotein O-like -8.46886
MRPS17 mitochondrial ribosomal protein S17 -8.46886
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -8.46886
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -8.45023
CSNK2A1 casein kinase 2, alpha 1 polypeptide -8.45023
KLHL41 kelch-like family member 41 -8.45023
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -8.45023
PDHB pyruvate dehydrogenase (lipoamide) beta -8.45023
PPP1R8 protein phosphatase 1, regulatory subunit 8 -8.45023
RBM18 RNA binding motif protein 18 -8.45023
TSPYL1 TSPY-like 1 -8.45023
KPNA4 karyopherin alpha 4 (importin alpha 3) -8.45023
CCT8 chaperonin containing TCP1, subunit 8 (theta) -8.45023
TSPAN12 tetraspanin 12 -8.45023
TIPRL TOR signaling pathway regulator -8.45023
TP53INP2 tumor protein p53 inducible nuclear protein 2 -8.45023
IPO7 importin 7 -8.45023
TECRL trans-2,3-enoyl-CoA reductase-like -8.45023
ADSL adenylosuccinate lyase -8.44281
USP38 ubiquitin specific peptidase 38 -8.44281
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -8.44281
SUB1 SUB1 homolog (S. cerevisiae) -8.44281
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -8.44267
MRS2 MRS2 magnesium transporter -8.44267
AKTIP AKT interacting protein -8.41243
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -8.39324
FH fumarate hydratase -8.39324
CUL3 cullin 3 -8.39324
WBP4 WW domain binding protein 4 -8.39324
CRIPT cysteine-rich PDZ-binding protein -8.38949
RAB18 RAB18, member RAS oncogene family -8.38142
TIGAR TP53 induced glycolysis regulatory phosphatase -8.37923
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 -8.37923
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -8.37923
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -8.37923
TSPYL5 TSPY-like 5 -8.37923
VDAC1 voltage-dependent anion channel 1 -8.35769
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -8.35769
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -8.34642
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -8.3393
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -8.3393
BVES blood vessel epicardial substance -8.3393
CLCN3 chloride channel, voltage-sensitive 3 -8.33753
MRPL47 mitochondrial ribosomal protein L47 -8.32771
NADK2 NAD kinase 2, mitochondrial -8.31967
DLAT dihydrolipoamide S-acetyltransferase -8.31967
ISOC1 isochorismatase domain containing 1 -8.31967
MRPS14 mitochondrial ribosomal protein S14 -8.31967
BCAP29 B-cell receptor-associated protein 29 -8.3193
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -8.31589
ACOT13 acyl-CoA thioesterase 13 -8.30649
CS citrate synthase -8.30649
MRPL30 mitochondrial ribosomal protein L30 -8.29626
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -8.29626
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -8.29438
FKBP3 FK506 binding protein 3, 25kDa -8.29438
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -8.27266
CDC5L cell division cycle 5-like -8.26676
PDHX pyruvate dehydrogenase complex, component X -8.26676
PLAA phospholipase A2-activating protein -8.26068
ATP5F1C ATP synthase F1 subunit gamma -8.24839
CCDC43 coiled-coil domain containing 43 -8.24292
MRPS10 mitochondrial ribosomal protein S10 -8.22662
TSN translin -8.19827
MRPL50 mitochondrial ribosomal protein L50 -8.19514
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -8.19514
BCAS2 breast carcinoma amplified sequence 2 -8.19514
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -8.19362
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -8.19362
DAP3 death associated protein 3 -8.18981
PGM1 phosphoglucomutase 1 -8.18981
MRPS31 mitochondrial ribosomal protein S31 -8.17713
UBE3A ubiquitin protein ligase E3A -8.15691
GTPBP8 GTP-binding protein 8 (putative) -8.14282
MRPL39 mitochondrial ribosomal protein L39 -8.13921
HCCS holocytochrome c synthase -8.13921
GCLM glutamate-cysteine ligase, modifier subunit -8.13921
SRRD SRR1 domain containing -8.13532
ADAM23 ADAM metallopeptidase domain 23 -8.11701
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -8.11556
PREP prolyl endopeptidase -8.10374
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -8.08098
TMX2 thioredoxin-related transmembrane protein 2 -8.07464
AP5M1 adaptor-related protein complex 5, mu 1 subunit -8.07346
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -8.07346
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -8.06801
VDAC2 voltage-dependent anion channel 2 -8.06801
ALAS1 5'-aminolevulinate synthase 1 -8.06801
IMMT inner membrane protein, mitochondrial -8.06085
OLA1 Obg-like ATPase 1 -8.06085
CUL2 cullin 2 -8.04813
ECPAS Ecm29 proteasome adaptor and scaffold -8.04813
RANBP6 RAN binding protein 6 -8.03145
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -8.01307
ZFAND6 zinc finger, AN1-type domain 6 -8.01307
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -8.01307
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -8.01253
USP10 ubiquitin specific peptidase 10 -8.01253
TXNDC9 thioredoxin domain containing 9 -8.01253
DCAF6 DDB1 and CUL4 associated factor 6 -8.01253
LMOD3 leiomodin 3 (fetal) -8.01186
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -8.01011
REEP5 receptor accessory protein 5 -8.01011
UBA3 ubiquitin-like modifier activating enzyme 3 -7.98923
LRP12 low density lipoprotein receptor-related protein 12 -7.98923
ASF1A anti-silencing function 1A histone chaperone -7.98923
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -7.98347
ARHGAP5 Rho GTPase activating protein 5 -7.98347
DNM1L dynamin 1-like -7.98347
ATP5F1B ATP synthase F1 subunit beta -7.98155
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -7.97383
METAP2 methionyl aminopeptidase 2 -7.95259
ETFDH electron-transferring-flavoprotein dehydrogenase -7.94797
SYAP1 synapse associated protein 1 -7.94241
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -7.94241
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -7.92767
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -7.92767
TMEM70 transmembrane protein 70 -7.92309
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -7.91898
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -7.91542
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -7.90573
TMEM117 transmembrane protein 117 -7.88898
TATDN3 TatD DNase domain containing 3 -7.88898
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -7.87808
SSBP1 single-stranded DNA binding protein 1, mitochondrial -7.87808
CYRIB CYFIP related Rac1 interactor B -7.87316
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -7.87316
DCTN4 dynactin 4 (p62) -7.86738
NCEH1 neutral cholesterol ester hydrolase 1 -7.86486
UQCRC2 ubiquinol-cytochrome c reductase core protein II -7.86243
GLO1 glyoxalase I -7.85814
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -7.85528
COP1 COP1 E3 ubiquitin ligase -7.85528
FAM120A family with sequence similarity 120A -7.84775
AKAP6 A kinase (PRKA) anchor protein 6 -7.83716