GTEx Nerve 20-29 vs 60-69 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

499 genes with high or low expression in GTEx Nerve 20-29 vs 60-69 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
EDA2R ectodysplasin A2 receptor 44.214
RASEF RAS and EF-hand domain containing 35.1128
CDKN2A cyclin-dependent kinase inhibitor 2A 35.1128
CORO2B coronin, actin binding protein, 2B 29.389
HNF4G hepatocyte nuclear factor 4, gamma 27.8277
PARP8 poly (ADP-ribose) polymerase family, member 8 27.5145
MIR34AHG MIR34A host gene 26.1793
PAPPA pregnancy-associated plasma protein A, pappalysin 1 26.0324
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 25.7948
HAND2 heart and neural crest derivatives expressed 2 25.7948
PYHIN1 pyrin and HIN domain family, member 1 25.6611
GSAP gamma-secretase activating protein 25.5972
HAND2-AS1 HAND2 antisense RNA 1 (head to head) 24.9875
ZMAT3 zinc finger, matrin-type 3 24.8263
PTCHD4 patched domain containing 4 24.0204
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 23.5208
HOXD10 homeobox D10 23.1793
NTNG1 netrin G1 23.0905
MYO5A myosin VA (heavy chain 12, myoxin) 23.042
RASGEF1C RasGEF domain family, member 1C 22.9615
HLA-DOA major histocompatibility complex, class II, DO alpha 22.4323
CNTN2 contactin 2 (axonal) 21.7442
HLA-DMA major histocompatibility complex, class II, DM alpha 19.7779
NTM neurotrimin 19.7581
KIF5A kinesin family member 5A 19.5894
RAP1GAP2 RAP1 GTPase activating protein 2 19.5894
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 19.5894
CIITA class II, major histocompatibility complex, transactivator 19.5303
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 19.5285
CSMD3 CUB and Sushi multiple domains 3 19.3342
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 19.2304
GALR1 galanin receptor 1 19.2187
GAP43 growth associated protein 43 19.2187
MGAT4C MGAT4 family, member C 19.0776
CYFIP2 cytoplasmic FMR1 interacting protein 2 19.04
DDB2 damage-specific DNA binding protein 2, 48kDa 19.04
COBL cordon-bleu WH2 repeat protein 18.9277
FRMD5 FERM domain containing 5 18.9249
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 18.887
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 18.6911
COL7A1 collagen, type VII, alpha 1 18.6829
L1CAM L1 cell adhesion molecule 18.5476
DNM3 dynamin 3 18.4295
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 18.3148
C2ORF88 chromosome 2 open reading frame 88 18.0861
MROH7 maestro heat-like repeat family member 7 17.9262
GRIK2 glutamate receptor, ionotropic, kainate 2 17.9002
SH3BP2 SH3-domain binding protein 2 17.9002
SHH sonic hedgehog 17.8243
TMOD2 tropomodulin 2 (neuronal) 17.7316
IL15 interleukin 15 17.7208
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 17.5914
MIR3142HG MIR3142 host gene 17.4318
AQP11 aquaporin 11 17.4318
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 17.1743
ANKRD6 ankyrin repeat domain 6 17.0741
OPCML opioid binding protein/cell adhesion molecule-like 17.0584
PLAG1 pleiomorphic adenoma gene 1 17.0223
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 16.8205
RUNX2 runt-related transcription factor 2 16.8205
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 16.5389
EPS8L2 EPS8-like 2 16.5091
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 16.4525
HOXD9 homeobox D9 16.4083
PALD1 phosphatase domain containing, paladin 1 16.3308
LSAMP limbic system-associated membrane protein 16.1934
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 16.1649
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 16.1649
BRSK1 BR serine/threonine kinase 1 16.1649
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 16.1546
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B 16.1119
FIGN fidgetin 16.0876
PCDHA10 protocadherin alpha 10 15.9748
FGF5 fibroblast growth factor 5 15.9258
TBC1D32 TBC1 domain family, member 32 15.9258
PARP10 poly (ADP-ribose) polymerase family, member 10 15.8124
MTSS2 MTSS I-BAR domain containing 2 15.8124
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 15.807
UNC13D unc-13 homolog D (C. elegans) 15.7683
TVP23A trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) 15.7117
TMEM229B transmembrane protein 229B 15.6937
ACP6 acid phosphatase 6, lysophosphatidic 15.6842
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 15.6814
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 15.6334
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 15.6334
LRRTM2 leucine rich repeat transmembrane neuronal 2 15.6334
TRIM9 tripartite motif containing 9 15.569
CCDC181 coiled-coil domain containing 181 15.5419
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 15.4972
PCDHA2 protocadherin alpha 2 15.2989
ADGRB3 adhesion G protein-coupled receptor B3 15.2051
WDR97 WD repeat domain 97 15.1753
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 15.1165
ITGB8 integrin, beta 8 15.029
PCDHA3 protocadherin alpha 3 14.9986
L3MBTL4 l(3)mbt-like 4 (Drosophila) 14.9986
ACOT11 acyl-CoA thioesterase 11 14.9223
BEX1 brain expressed, X-linked 1 14.8669
PATL2 protein associated with topoisomerase II homolog 2 (yeast) 14.77
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 14.736
DUSP2 dual specificity phosphatase 2 14.6904
FLRT1 fibronectin leucine rich transmembrane protein 1 14.603
INSC inscuteable homolog (Drosophila) 14.603
CELF6 CUGBP, Elav-like family member 6 14.5766
NEFL neurofilament, light polypeptide 14.5602
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 14.3472
CPNE7 copine VII 14.3303
REC8 REC8 meiotic recombination protein 14.2666
UBA7 ubiquitin-like modifier activating enzyme 7 14.1051
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 14.0196
DSC3 desmocollin 3 13.9694
CNKSR3 CNKSR family member 3 13.9489
STARD4 StAR-related lipid transfer (START) domain containing 4 13.8365
RALYL RALY RNA binding protein-like 13.831
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 13.831
ESPN espin 13.8169
KRTCAP3 keratinocyte associated protein 3 13.7828
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 13.7828
EOMES eomesodermin 13.7715
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 13.7703
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 13.7195
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 13.669
CNIH3 cornichon family AMPA receptor auxiliary protein 3 13.669
LINC00327 long intergenic non-protein coding RNA 327 13.6529
PCDHB2 protocadherin beta 2 13.6303
ZMAT1 zinc finger, matrin-type 1 13.5693
HLA-DMB major histocompatibility complex, class II, DM beta 13.5528
RADX RPA1 related single stranded DNA binding protein, X-linked 13.546
EPHA6 EPH receptor A6 13.5455
ADD3 adducin 3 (gamma) 13.5455
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 13.5385
RFX5 regulatory factor X, 5 (influences HLA class II expression) 13.5337
CDKN2B-AS1 CDKN2B antisense RNA 1 13.5337
SMIM5 small integral membrane protein 5 13.3965
UCN urocortin 13.3895
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 13.3518
DRD2 dopamine receptor D2 13.2986
FCHSD1 FCH and double SH3 domains 1 13.2776
MARCHF1 membrane associated ring-CH-type finger 1 13.2755
C1ORF198 chromosome 1 open reading frame 198 13.2614
NIM1K NIM1 serine/threonine protein kinase 13.1336
SAXO4 stabilizer of axonemal microtubules 4 13.0009
ZNF516 zinc finger protein 516 12.9804
STK32A serine/threonine kinase 32A 12.9309
APC2 adenomatosis polyposis coli 2 12.9201
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 12.8984
FRMPD3 FERM and PDZ domain containing 3 12.8533
LINC00466 long intergenic non-protein coding RNA 466 12.8512
SLF2 SMC5-SMC6 complex localization factor 2 12.8402
PLAAT4 phospholipase A and acyltransferase 4 12.7901
CASP1 caspase 1, apoptosis-related cysteine peptidase 12.7628
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 12.7476
GSTO2 glutathione S-transferase omega 2 12.6915
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 12.5902
FAM181B family with sequence similarity 181, member B 12.5902
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 12.5245
PCNX2 pecanex 2 12.4785
LEF1 lymphoid enhancer-binding factor 1 12.4525
MRO maestro 12.452
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 12.3912
ALK anaplastic lymphoma receptor tyrosine kinase 12.3912
HLA-DRA major histocompatibility complex, class II, DR alpha 12.3054
CHL1-AS1 CHL1 antisense RNA 1 12.3043
DRAXIN dorsal inhibitory axon guidance protein 12.302
POLI polymerase (DNA directed) iota 12.2819
TP53INP2 tumor protein p53 inducible nuclear protein 2 12.2734
DIRAS3 DIRAS family, GTP-binding RAS-like 3 12.2026
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 12.1835
STRC stereocilin 12.1835
MNMIP1 manchette microtubule inner protein 1 12.1678
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 12.1675
LINC01550 long intergenic non-protein coding RNA 1550 12.1568
PBX4 pre-B-cell leukemia homeobox 4 12.0858
RXRG retinoid X receptor, gamma 12.084
GDNF glial cell derived neurotrophic factor 12.0797
BHLHE22 basic helix-loop-helix family, member e22 12.0642
NAT14 N-acetyltransferase 14 (GCN5-related, putative) 12.0333
GAA glucosidase, alpha; acid 11.9646
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 11.9636
C20ORF203 chromosome 20 open reading frame 203 11.9636
GFRA3 GDNF family receptor alpha 3 11.9448
PDE8A phosphodiesterase 8A 11.9324
MYO15B myosin XVB 11.9297
FDXR ferredoxin reductase 11.9113
PLXNA3 plexin A3 11.9113
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 11.9099
FBXO44 F-box protein 44 11.9059
ENO2 enolase 2 (gamma, neuronal) 11.9055
MYRF myelin regulatory factor 11.874
LINC02987 long intergenic non-protein coding RNA 2987 11.8224
ACSS3 acyl-CoA synthetase short-chain family member 3 11.8218
INTS6L integrator complex subunit 6 like 11.8218
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 11.82
NR2F1-AS1 NR2F1 antisense RNA 1 11.8064
CERKL ceramide kinase-like 11.7456
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 11.7137
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 11.7029
MAPK4 mitogen-activated protein kinase 4 11.6933
LIN7A lin-7 homolog A (C. elegans) 11.6772
CHIC1 cysteine-rich hydrophobic domain 1 11.6737
CC2D1A coiled-coil and C2 domain containing 1A 11.658
CAPN5 calpain 5 11.609
LPAR2 lysophosphatidic acid receptor 2 11.5956
MAN2A2 mannosidase, alpha, class 2A, member 2 11.5669
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 11.5246
SLC35F3 solute carrier family 35, member F3 11.5107
CDK9 cyclin-dependent kinase 9 11.5077
ACSS1 acyl-CoA synthetase short-chain family member 1 11.4785
MOV10 Mov10 RISC complex RNA helicase 11.4785
ACSBG1 acyl-CoA synthetase bubblegum family member 1 11.4767
GRIK4 glutamate receptor, ionotropic, kainate 4 11.4767
TP53INP1 tumor protein p53 inducible nuclear protein 1 11.4672
ZNG1C Zn regulated GTPase metalloprotein activator 1C 11.4429
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 11.4034
TTYH1 tweety family member 1 11.3888
ACBD4 acyl-CoA binding domain containing 4 11.3699
TRPS1 trichorhinophalangeal syndrome I 11.3419
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 11.3419
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 11.3256
CCDC14 coiled-coil domain containing 14 11.2918
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 11.2846
ARHGAP32 Rho GTPase activating protein 32 11.2824
LINC00173 long intergenic non-protein coding RNA 173 11.2824
COL19A1 collagen, type XIX, alpha 1 11.2414
PLCE1 phospholipase C, epsilon 1 11.2212
STKLD1 serine/threonine kinase-like domain containing 1 11.219
OXCT1-AS1 OXCT1 antisense RNA 1 11.1511
ZCWPW1 zinc finger, CW type with PWWP domain 1 11.1492
CEP70 centrosomal protein 70kDa 11.1448
KCTD1 potassium channel tetramerization domain containing 1 11.1424
TLR6 toll-like receptor 6 11.124
LIMD2 LIM domain containing 2 11.1213
ITGB4 integrin, beta 4 11.1213
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 11.118
GEMIN8 gem (nuclear organelle) associated protein 8 11.1138
ARMCX4 armadillo repeat containing, X-linked 4 11.1138
HOXC8 homeobox C8 11.1086
HLA-F-AS1 HLA-F antisense RNA 1 11.0882
MYO1E myosin IE 11.087
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 11.0689
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 11.0507
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 11.0507
PAXBP1 PAX3 and PAX7 binding protein 1 11.0442
SYT10 synaptotagmin X 11.0402
LMF2 lipase maturation factor 2 11.0267
ARHGAP33 Rho GTPase activating protein 33 11.0009
MSH5 mutS homolog 5 10.9791
TMEM178B transmembrane protein 178B 10.966
MROH6 maestro heat-like repeat family member 6 10.9564
NIBAN3 niban apoptosis regulator 3 10.9339

decreased expression

Symbol Name Standardized Value
ITGB5 integrin, beta 5 -26.0324
TMEM132C transmembrane protein 132C -24.3888
PEA15 phosphoprotein enriched in astrocytes 15 -23.2658
WSB2 WD repeat and SOCS box containing 2 -22.186
ZDHHC3 zinc finger, DHHC-type containing 3 -21.6034
VLDLR very low density lipoprotein receptor -20.5931
PCSK6 proprotein convertase subtilisin/kexin type 6 -19.6084
DMTN dematin actin binding protein -19.3806
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -19.3717
ZNF518B zinc finger protein 518B -18.4789
ELOVL1 ELOVL fatty acid elongase 1 -18.347
TGFA transforming growth factor, alpha -18.0861
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -17.9762
ACP2 acid phosphatase 2, lysosomal -17.9762
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -17.9002
MLIP muscular LMNA-interacting protein -17.9002
TESK2 testis-specific kinase 2 -17.6743
FAM234A family with sequence similarity 234 member A -17.4341
GDE1 glycerophosphodiester phosphodiesterase 1 -17.4341
RNF10 ring finger protein 10 -17.2986
FILIP1 filamin A interacting protein 1 -17.2671
CCDC192 coiled-coil domain containing 192 -17.1813
MYO1B myosin IB -17.0584
MYLIP myosin regulatory light chain interacting protein -17.0581
AK4 adenylate kinase 4 -17.0581
RIMS3 regulating synaptic membrane exocytosis 3 -17.0203
BOK BCL2-related ovarian killer -16.8205
CENPN centromere protein N -16.1649
CCDC6 coiled-coil domain containing 6 -16.1177
PEDS1 plasmanylethanolamine desaturase 1 -16.1177
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing -16.1177
THRB thyroid hormone receptor, beta -15.9258
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -15.8862
RILP Rab interacting lysosomal protein -15.7683
DDAH1 dimethylarginine dimethylaminohydrolase 1 -15.4679
MOB3B MOB kinase activator 3B -15.2592
LGI3 leucine-rich repeat LGI family, member 3 -15.2051
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -15.1911
CHEK2 checkpoint kinase 2 -15.1438
ZDHHC14 zinc finger, DHHC-type containing 14 -15.0862
S100A1 S100 calcium binding protein A1 -15.029
MSRA methionine sulfoxide reductase A -14.8082
NFASC neurofascin -14.77
HNMT histamine N-methyltransferase -14.6126
LOC119746555 uncharacterized LOC119746555 -14.5038
FBXL7 F-box and leucine-rich repeat protein 7 -14.4431
CEMIP2 cell migration inducing hyaluronidase 2 -14.4431
GHR growth hormone receptor -14.3593
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -14.3188
SNCG synuclein, gamma (breast cancer-specific protein 1) -14.3188
MYL9 myosin, light chain 9, regulatory -14.3188
LIMCH1 LIM and calponin homology domains 1 -14.3169
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -14.2874
PRXL2A peroxiredoxin like 2A -14.2757
SPTB spectrin, beta, erythrocytic -14.2334
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -13.9489
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -13.9176
C19ORF12 chromosome 19 open reading frame 12 -13.8992
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -13.8573
OSBPL1A oxysterol binding protein-like 1A -13.811
ELOA elongin A -13.811
MN1 meningioma (disrupted in balanced translocation) 1 -13.7195
MGLL monoglyceride lipase -13.7195
AIF1L allograft inflammatory factor 1-like -13.7195
PLPP3 phospholipid phosphatase 3 -13.7195
FBLN5 fibulin 5 -13.669
PI15 peptidase inhibitor 15 -13.669
SPRING1 SREBF pathway regulator in golgi 1 -13.5337
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -13.5322
ATP9A ATPase, class II, type 9A -13.531
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -13.4384
LPL lipoprotein lipase -13.3784
CAPN11 calpain 11 -13.2986
RAPSN receptor-associated protein of the synapse -13.281
GID4 GID complex subunit 4 -13.2185
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -13.2172
MAP7D1 MAP7 domain containing 1 -13.1018
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -13.0987
CAV2 caveolin 2 -13.0485
MTPN myotrophin -12.9667
HAGH hydroxyacylglutathione hydrolase -12.9573
SEPTIN11 septin 11 -12.9351
SSTR2 somatostatin receptor 2 -12.9351
PPP1R16B protein phosphatase 1, regulatory subunit 16B -12.8984
KCMF1 potassium channel modulatory factor 1 -12.8984
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 -12.8512
DIAPH2 diaphanous-related formin 2 -12.8352
CNTF ciliary neurotrophic factor -12.8093
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -12.8093
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 -12.7918
CUL3 cullin 3 -12.7802
RANBP17 RAN binding protein 17 -12.7548
NOL7 nucleolar protein 7, 27kDa -12.7271
GLDC glycine dehydrogenase (decarboxylating) -12.7219
ACOX1 acyl-CoA oxidase 1, palmitoyl -12.6915
ZNF551 zinc finger protein 551 -12.6527
UBA2 ubiquitin-like modifier activating enzyme 2 -12.5902
RAET1E retinoic acid early transcript 1E -12.5902
PRUNE2 prune homolog 2 (Drosophila) -12.5526
ANXA4 annexin A4 -12.5499
DGAT2 diacylglycerol O-acyltransferase 2 -12.5083
SNTA1 syntrophin, alpha 1 -12.4863
BAG5 BCL2-associated athanogene 5 -12.4863
ATG9A autophagy related 9A -12.452
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -12.4441
KIF3B kinesin family member 3B -12.4339
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase -12.4022
SIRPA signal-regulatory protein alpha -12.3906
KREMEN1 kringle containing transmembrane protein 1 -12.3862
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -12.3862
CLDN14 claudin 14 -12.3736
GJA5 gap junction protein, alpha 5, 40kDa -12.3541
LGI2 leucine-rich repeat LGI family, member 2 -12.3472
GJA4 gap junction protein, alpha 4, 37kDa -12.2916
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -12.2734
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -12.2081
CPEB4 cytoplasmic polyadenylation element binding protein 4 -12.1945
DRP2 dystrophin related protein 2 -12.1945
ABHD5 abhydrolase domain containing 5 -12.1785
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -12.1635
FSCN1 fascin actin-bundling protein 1 -12.1611
FBXL16 F-box and leucine-rich repeat protein 16 -12.1378
SQOR sulfide quinone oxidoreductase -12.1378
SYNDIG1 synapse differentiation inducing 1 -12.1003
TPRG1L tumor protein p63 regulated 1-like -12.0887
HSPA4 heat shock 70kDa protein 4 -12.0624
RACGAP1 Rac GTPase activating protein 1 -11.9324
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -11.9236
ACP7 acid phosphatase 7, tartrate resistant (putative) -11.9099
AGTR1 angiotensin II receptor, type 1 -11.8739
UBE3C ubiquitin protein ligase E3C -11.8316
PEX19 peroxisomal biogenesis factor 19 -11.7531
SPAG5 sperm associated antigen 5 -11.7141
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -11.6933
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -11.6933
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) -11.6727
KIF5C kinesin family member 5C -11.6121
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 -11.5957
SEPHS2 selenophosphate synthetase 2 -11.5603
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -11.5
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -11.4767
DERA deoxyribose-phosphate aldolase (putative) -11.4767
CAV1 caveolin 1, caveolae protein, 22kDa -11.4767
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -11.4767
SMIM13 small integral membrane protein 13 -11.4325
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -11.4325
UNC119 unc-119 homolog (C. elegans) -11.4325
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -11.3917
TYRO3 TYRO3 protein tyrosine kinase -11.3798
INPP5K inositol polyphosphate-5-phosphatase K -11.3475
ARID3C AT rich interactive domain 3C (BRIGHT-like) -11.3415
CCDC25 coiled-coil domain containing 25 -11.3256
LRRC8A leucine rich repeat containing 8 family, member A -11.3256
ACBD7 acyl-CoA binding domain containing 7 -11.2824
ECEL1 endothelin converting enzyme-like 1 -11.2824
PVR poliovirus receptor -11.2823
AVEN apoptosis, caspase activation inhibitor -11.2262
DCAF11 DDB1 and CUL4 associated factor 11 -11.2023
MEGF11 multiple EGF-like-domains 11 -11.1662
ETFA electron-transfer-flavoprotein, alpha polypeptide -11.1571
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -11.1571
TBX3 T-box 3 -11.1227
RNF185 ring finger protein 185 -11.1227
ATMIN ATM interactor -11.1213
TCAIM T cell activation inhibitor, mitochondrial -11.1213
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -11.1158
ETNPPL ethanolamine-phosphate phospho-lyase -11.1138
PC pyruvate carboxylase -11.0882
HAPSTR1 HUWE1 associated protein modifying stress responses -11.0267
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -11.0244
GSTM3 glutathione S-transferase mu 3 (brain) -11.0204
MARCHF10 membrane associated ring-CH-type finger 10 -10.9473
FAIM2 Fas apoptotic inhibitory molecule 2 -10.9291
GAS2L1 growth arrest-specific 2 like 1 -10.92
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 -10.8977
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -10.8639
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 -10.8555
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -10.8501
HIBADH 3-hydroxyisobutyrate dehydrogenase -10.8463
NANOS1 nanos homolog 1 (Drosophila) -10.8436
MAPKAP1 mitogen-activated protein kinase associated protein 1 -10.7949
HAPLN2 hyaluronan and proteoglycan link protein 2 -10.7949
TPST2 tyrosylprotein sulfotransferase 2 -10.7949
OR51E2 olfactory receptor, family 51, subfamily E, member 2 -10.7721
KIF23 kinesin family member 23 -10.7601
TES testin LIM domain protein -10.7547
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 -10.7547
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -10.7546
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -10.7459
DCAF6 DDB1 and CUL4 associated factor 6 -10.7132
SERBP1 SERPINE1 mRNA binding protein 1 -10.7119
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -10.706
CLIP3 CAP-GLY domain containing linker protein 3 -10.6864
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -10.6864
ACOT7 acyl-CoA thioesterase 7 -10.6773
DUSP14 dual specificity phosphatase 14 -10.6517
NLRX1 NLR family member X1 -10.6449
ATP5F1A ATP synthase F1 subunit alpha -10.6413
ITPKB inositol-trisphosphate 3-kinase B -10.63
ADO 2-aminoethanethiol (cysteamine) dioxygenase -10.6123
ACTRT3 actin-related protein T3 -10.6091
INKA2 inka box actin regulator 2 -10.608
GAMT guanidinoacetate N-methyltransferase -10.608
VDAC2 voltage-dependent anion channel 2 -10.6078
PCOLCE2 procollagen C-endopeptidase enhancer 2 -10.5952
HYLS1 hydrolethalus syndrome 1 -10.59
SMCO3 single-pass membrane protein with coiled-coil domains 3 -10.5572
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -10.4956
FZD5 frizzled class receptor 5 -10.4878
NKD1 naked cuticle homolog 1 (Drosophila) -10.468
LYPD6 LY6/PLAUR domain containing 6 -10.468
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -10.4602
GJB1 gap junction protein, beta 1, 32kDa -10.4512
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -10.4425
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -10.4313
PALMD palmdelphin -10.4298
PRUNE1 prune exopolyphosphatase 1 -10.4086
RNF26 ring finger protein 26 -10.378
RGN regucalcin -10.3749
ZFAND3 zinc finger, AN1-type domain 3 -10.3749
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 -10.3749
KPNA3 karyopherin alpha 3 (importin alpha 4) -10.3749
DPH3 diphthamide biosynthesis 3 -10.3749
KLHDC3 kelch domain containing 3 -10.3565
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 -10.3457
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -10.3457
PALS1 protein associated with LIN7 1, MAGUK p55 family member -10.3374
ISOC1 isochorismatase domain containing 1 -10.3211
ACKR3 atypical chemokine receptor 3 -10.3141
P3H2 prolyl 3-hydroxylase 2 -10.3068
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -10.3011
TTC9 tetratricopeptide repeat domain 9 -10.2904
LGALS8 lectin, galactoside-binding, soluble, 8 -10.2904
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -10.2904
FKBPL FK506 binding protein like -10.2832
NCKAP1 NCK-associated protein 1 -10.2789
RBPMS2 RNA binding protein with multiple splicing 2 -10.2347
HSPB2 heat shock 27kDa protein 2 -10.2207
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 -10.2101
RASL11A RAS-like, family 11, member A -10.204
EVI5L ecotropic viral integration site 5-like -10.1904
PPA1 pyrophosphatase (inorganic) 1 -10.1882
CLEC16A C-type lectin domain family 16, member A -10.1763
PTS 6-pyruvoyltetrahydropterin synthase -10.1674
GRSF1 G-rich RNA sequence binding factor 1 -10.1332
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 -10.1188
PCDH18 protocadherin 18 -10.1142
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -10.1142
SDK1 sidekick cell adhesion molecule 1 -10.0916