GTEx Nerve 20-29 vs 70-79 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

500 genes with high or low expression in GTEx Nerve 20-29 vs 70-79 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
EDA2R ectodysplasin A2 receptor 26.0854
RASEF RAS and EF-hand domain containing 22.0611
NTNG1 netrin G1 20.114
NTM neurotrimin 19.002
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 19.002
FRMD5 FERM domain containing 5 19.002
CDKN2A cyclin-dependent kinase inhibitor 2A 19.002
PARP8 poly (ADP-ribose) polymerase family, member 8 17.7048
RUNX2 runt-related transcription factor 2 17.4003
RASGEF1C RasGEF domain family, member 1C 17.225
HNF4G hepatocyte nuclear factor 4, gamma 16.9433
AQP11 aquaporin 11 16.5858
COL7A1 collagen, type VII, alpha 1 16.5858
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 16.5345
HOXD10 homeobox D10 16.5345
CYFIP2 cytoplasmic FMR1 interacting protein 2 16.5253
HAND2 heart and neural crest derivatives expressed 2 16.3925
L1CAM L1 cell adhesion molecule 16.2664
SLC35F3 solute carrier family 35, member F3 15.9511
CORO2B coronin, actin binding protein, 2B 15.9511
LRRTM2 leucine rich repeat transmembrane neuronal 2 15.4931
KIF5A kinesin family member 5A 15.1422
PAPPA pregnancy-associated plasma protein A, pappalysin 1 15.124
HAND2-AS1 HAND2 antisense RNA 1 (head to head) 15.1233
SH3BP2 SH3-domain binding protein 2 14.949
MYRF myelin regulatory factor 14.935
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 14.935
APC2 adenomatosis polyposis coli 2 14.935
ZMAT3 zinc finger, matrin-type 3 14.935
TMOD2 tropomodulin 2 (neuronal) 14.935
LSAMP limbic system-associated membrane protein 14.935
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 14.8884
OPCML opioid binding protein/cell adhesion molecule-like 14.887
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 14.8148
PTCHD4 patched domain containing 4 14.744
ADGRB3 adhesion G protein-coupled receptor B3 14.6535
RAP1GAP2 RAP1 GTPase activating protein 2 14.444
CNTN2 contactin 2 (axonal) 14.3335
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 14.2111
ITGB8 integrin, beta 8 14.171
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 14.1525
LINC00327 long intergenic non-protein coding RNA 327 14.0967
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 14.0839
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 14.0293
SHH sonic hedgehog 13.9033
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 13.9033
GALR1 galanin receptor 1 13.9033
GAP43 growth associated protein 43 13.7826
HOXD9 homeobox D9 13.7021
FGF5 fibroblast growth factor 5 13.6497
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 13.6233
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 13.6233
COBL cordon-bleu WH2 repeat protein 13.4773
NEFL neurofilament, light polypeptide 13.2906
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 13.2346
MYO5A myosin VA (heavy chain 12, myoxin) 13.1224
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 13.1002
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 12.9757
GSAP gamma-secretase activating protein 12.8338
ANKRD6 ankyrin repeat domain 6 12.8067
MIR3142HG MIR3142 host gene 12.7934
EPHA6 EPH receptor A6 12.772
F2RL2 coagulation factor II (thrombin) receptor-like 2 12.7652
MIR34AHG MIR34A host gene 12.6777
RXRG retinoid X receptor, gamma 12.6777
PCDHB6 protocadherin beta 6 12.6777
PLAAT4 phospholipase A and acyltransferase 4 12.5965
GRIK2 glutamate receptor, ionotropic, kainate 2 12.4422
TMEM229B transmembrane protein 229B 12.4422
TCF7 transcription factor 7 (T-cell specific, HMG-box) 12.4422
SMIM5 small integral membrane protein 5 12.3997
MTSS2 MTSS I-BAR domain containing 2 12.2642
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 12.2048
GBP1P1 guanylate binding protein 1, interferon-inducible pseudogene 1 12.1211
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 12.1201
ZNF516 zinc finger protein 516 12.0907
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 12.0734
ACP6 acid phosphatase 6, lysophosphatidic 11.9807
DRAXIN dorsal inhibitory axon guidance protein 11.9807
GFRA3 GDNF family receptor alpha 3 11.8607
EPS8L2 EPS8-like 2 11.8607
DNM3 dynamin 3 11.8607
SCN9A sodium channel, voltage gated, type IX alpha subunit 11.8468
DUX4L50 double homeobox 4 like 50 (pseudogene) 11.8253
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 11.8253
KCTD1 potassium channel tetramerization domain containing 1 11.6831
CSMD3 CUB and Sushi multiple domains 3 11.6783
MICALL2 MICAL-like 2 11.6369
STK32A serine/threonine kinase 32A 11.6369
TRIM9 tripartite motif containing 9 11.6369
LGI4 leucine-rich repeat LGI family, member 4 11.6167
ITGB4 integrin, beta 4 11.5957
GOLGA8VP golgin A8 family, member V, pseudogene 11.5952
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 11.5365
TLL2 tolloid-like 2 11.5365
DDB2 damage-specific DNA binding protein 2, 48kDa 11.5292
FAM171A1 family with sequence similarity 171, member A1 11.5292
NIM1K NIM1 serine/threonine protein kinase 11.5292
TNK1 tyrosine kinase, non-receptor, 1 11.5169
SEPTIN7-DT SEPTIN7 divergent transcript 11.4724
BTC betacellulin 11.4615
RALYL RALY RNA binding protein-like 11.4615
BRSK1 BR serine/threonine kinase 1 11.4615
SYT10 synaptotagmin X 11.4615
MDK midkine (neurite growth-promoting factor 2) 11.3541
DRD2 dopamine receptor D2 11.2883
CNIH3 cornichon family AMPA receptor auxiliary protein 3 11.2871
STEAP1B STEAP family member 1B 11.2682
CPNE7 copine VII 11.1782
IL15 interleukin 15 11.173
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 11.1464
SORCS1 sortilin-related VPS10 domain containing receptor 1 11.1464
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 11.1464
POLH polymerase (DNA directed), eta 11.1438
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 11.1355
DNM1P47 dynamin 1 pseudogene 47 11.1142
SOX2-OT SOX2 overlapping transcript 11.1073
GRIK3 glutamate receptor, ionotropic, kainate 3 11.1073
NRN1 neuritin 1 11.053
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 11.0297
TMTC4 transmembrane and tetratricopeptide repeat containing 4 11.0276
HLA-DOA major histocompatibility complex, class II, DO alpha 11.0202
ID2-AS1 ID2 antisense RNA 1 (head to head) 10.9893
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 10.9804
TMEM176B transmembrane protein 176B 10.9804
FAM181B family with sequence similarity 181, member B 10.9513
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 10.9513
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 10.9387
IRF1-AS1 IRF1 antisense RNA 1 10.9034
NRXN1 neurexin 1 10.8956
FIGN fidgetin 10.892
PALD1 phosphatase domain containing, paladin 1 10.892
REC8 REC8 meiotic recombination protein 10.8774
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 10.8653
BEX1 brain expressed, X-linked 1 10.8105
CIITA class II, major histocompatibility complex, transactivator 10.742
MYO1E myosin IE 10.693
CADM1 cell adhesion molecule 1 10.6559
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 10.6434
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 10.6343
SCN7A sodium channel, voltage gated, type VII alpha subunit 10.6343
IL17RE interleukin 17 receptor E 10.6343
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 10.616
TVP23A trans-golgi network vesicle protein 23 homolog A (S. cerevisiae) 10.55
TOX3 TOX high mobility group box family member 3 10.4932
GSTO2 glutathione S-transferase omega 2 10.4557
CASP1 caspase 1, apoptosis-related cysteine peptidase 10.4092
FHDC1 FH2 domain containing 1 10.4092
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 10.4081
AHR aryl hydrocarbon receptor 10.3764
LZTS1 leucine zipper, putative tumor suppressor 1 10.3434
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 10.3365
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 10.2888
BHLHE22 basic helix-loop-helix family, member e22 10.2361
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 10.14
MYOT myotilin 10.1274
PRDM16 PR domain containing 16 10.0653
ADD3 adducin 3 (gamma) 10.0574
STARD13 StAR-related lipid transfer (START) domain containing 13 10.0574
DOK6 docking protein 6 10.0399
CEP170P1 centrosomal protein 170kDa pseudogene 1 9.93532
SCN8A sodium channel, voltage gated, type VIII alpha subunit 9.92469
SYNPO synaptopodin 9.91779
FLRT1 fibronectin leucine rich transmembrane protein 1 9.90351
TRDN triadin 9.89429
ZNF503 zinc finger protein 503 9.88867
LRP1B low density lipoprotein receptor-related protein 1B 9.88528
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 9.85387
PYHIN1 pyrin and HIN domain family, member 1 9.85178
CHL1-AS2 CHL1 antisense RNA 2 9.85178
GSN-AS1 GSN antisense RNA 1 9.73623
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 9.70221
CERKL ceramide kinase-like 9.70221
TRAM1L1 translocation associated membrane protein 1-like 1 9.65599
NCAM1 neural cell adhesion molecule 1 9.62399
GDNF glial cell derived neurotrophic factor 9.60246
CNKSR3 CNKSR family member 3 9.60246
SLF2 SMC5-SMC6 complex localization factor 2 9.55046
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 9.53224
PARP10 poly (ADP-ribose) polymerase family, member 10 9.50216
GRIK4 glutamate receptor, ionotropic, kainate 4 9.50067
RYR1 ryanodine receptor 1 (skeletal) 9.4621
DDO D-aspartate oxidase 9.45097
RAD9B RAD9 homolog B (S. pombe) 9.40011
SYCP2 synaptonemal complex protein 2 9.40011
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 9.35997
RADX RPA1 related single stranded DNA binding protein, X-linked 9.35997
ABLIM3 actin binding LIM protein family, member 3 9.35079
UNC13D unc-13 homolog D (C. elegans) 9.34898
MAN2A2 mannosidase, alpha, class 2A, member 2 9.34898
TMEM176A transmembrane protein 176A 9.30784
RAB38 RAB38, member RAS oncogene family 9.26779
INSC inscuteable homolog (Drosophila) 9.26779
SLC22A17 solute carrier family 22, member 17 9.21807
PCDHA2 protocadherin alpha 2 9.15174
PRIMA1 proline rich membrane anchor 1 9.15068
PLCE1 phospholipase C, epsilon 1 9.14008
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 9.12054
LEF1 lymphoid enhancer-binding factor 1 9.12045
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 9.12045
TBC1D32 TBC1 domain family, member 32 9.0906
FREM2 FRAS1 related extracellular matrix protein 2 9.0872
TTYH1 tweety family member 1 9.07724
EPHA3 EPH receptor A3 9.06744
ALK anaplastic lymphoma receptor tyrosine kinase 9.03351
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 8.97003
MROH7 maestro heat-like repeat family member 7 8.9289
MACROD2 MACRO domain containing 2 8.91913
PLAG1 pleiomorphic adenoma gene 1 8.91365
ST3GAL6-AS1 ST3GAL6 antisense RNA 1 8.90935
LIMD2 LIM domain containing 2 8.8975
GBP1 guanylate binding protein 1, interferon-inducible 8.89017
HOXC8 homeobox C8 8.85769
EFCAB5 EF-hand calcium binding domain 5 8.84862
SP140L SP140 nuclear body protein-like 8.8145
ZNF385C zinc finger protein 385C 8.79961
TFAP2A-AS1 TFAP2A antisense RNA 1 8.79912
CEBPB-AS1 CEBPB antisense RNA 1 8.79176
LINC00900 long intergenic non-protein coding RNA 900 8.76527
ACOT11 acyl-CoA thioesterase 11 8.76245
EOMES eomesodermin 8.75345
TMEM178B transmembrane protein 178B 8.73747
GPR155 G protein-coupled receptor 155 8.73084
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 8.72291
KIFC3 kinesin family member C3 8.71025
GPALPP1 GPALPP motifs containing 1 8.70819
SLC44A3 solute carrier family 44, member 3 8.67509
LINC00484 long intergenic non-protein coding RNA 484 8.62199
SPATA13 spermatogenesis associated 13 8.61769
PRDM5 PR domain containing 5 8.61769
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 8.59831
HLA-DMA major histocompatibility complex, class II, DM alpha 8.59699
PRSS23 protease, serine, 23 8.57103
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 8.56231
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 8.55876
LNCTAM34A long non coding transcriptional activator of miR34a 8.55876
LINC00475 long intergenic non-protein coding RNA 475 8.55876
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 8.5385
MGAT4C MGAT4 family, member C 8.51945
KRT16 keratin 16, type I 8.51216
LRRC4 leucine rich repeat containing 4 8.50494
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 8.49064
WDR97 WD repeat domain 97 8.48257
ANO5 anoctamin 5 8.44151
LINC01550 long intergenic non-protein coding RNA 1550 8.44132
F2R coagulation factor II (thrombin) receptor 8.40689
NR2F2-AS1 NR2F2 antisense RNA 1 8.40689
ZNF853 zinc finger protein 853 8.38773
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 8.37604
PTPRJ protein tyrosine phosphatase, receptor type, J 8.33871

decreased expression

Symbol Name Standardized Value
MYLIP myosin regulatory light chain interacting protein -15.1422
ITGB5 integrin, beta 5 -14.9669
TMEM132C transmembrane protein 132C -14.6535
AGTR1 angiotensin II receptor, type 1 -14.4864
COL12A1 collagen, type XII, alpha 1 -13.1002
ZNF518B zinc finger protein 518B -13.1002
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -12.8067
GAS1 growth arrest-specific 1 -12.4986
ZDHHC3 zinc finger, DHHC-type containing 3 -12.4422
PEA15 phosphoprotein enriched in astrocytes 15 -12.3986
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -12.2642
ACP2 acid phosphatase 2, lysosomal -12.1507
TGFA transforming growth factor, alpha -11.6831
NTN1 netrin 1 -11.6831
WSB2 WD repeat and SOCS box containing 2 -11.6449
DMTN dematin actin binding protein -11.6167
THRB thyroid hormone receptor, beta -11.5952
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -11.5952
PCOLCE2 procollagen C-endopeptidase enhancer 2 -11.4292
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -11.0579
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -11.041
DKK2 dickkopf WNT signaling pathway inhibitor 2 -10.9513
ELOVL1 ELOVL fatty acid elongase 1 -10.892
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -10.7823
MAMDC2 MAM domain containing 2 -10.7665
GDE1 glycerophosphodiester phosphodiesterase 1 -10.6971
NPR1 natriuretic peptide receptor 1 -10.5757
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -10.55
KREMEN1 kringle containing transmembrane protein 1 -10.4373
S100A1 S100 calcium binding protein A1 -10.4295
GCLM glutamate-cysteine ligase, modifier subunit -10.3218
TSKU tsukushi, small leucine rich proteoglycan -10.2263
SEPTIN11 septin 11 -10.1618
PRXL2A peroxiredoxin like 2A -10.0399
MN1 meningioma (disrupted in balanced translocation) 1 -10.0165
GRK5 G protein-coupled receptor kinase 5 -10.0043
MOB3B MOB kinase activator 3B -10.0043
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -9.98897
DDAH1 dimethylarginine dimethylaminohydrolase 1 -9.94419
BOK BCL2-related ovarian killer -9.92469
MGLL monoglyceride lipase -9.89429
CLDN14 claudin 14 -9.88867
ZBTB7B zinc finger and BTB domain containing 7B -9.78737
WASF3 WAS protein family, member 3 -9.73623
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -9.73165
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -9.73165
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 -9.70544
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -9.6836
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 -9.55099
ZEB1 zinc finger E-box binding homeobox 1 -9.55046
S100A13 S100 calcium binding protein A13 -9.52095
AOX1 aldehyde oxidase 1 -9.46371
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -9.43044
ELOA elongin A -9.34898
RAI2 retinoic acid induced 2 -9.30784
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -9.2528
GHR growth hormone receptor -9.24847
RILP Rab interacting lysosomal protein -9.23234
TES testin LIM domain protein -9.22972
PROCR protein C receptor, endothelial -9.16491
WNT11 wingless-type MMTV integration site family, member 11 -9.16491
CAV1 caveolin 1, caveolae protein, 22kDa -9.14008
ACOX1 acyl-CoA oxidase 1, palmitoyl -9.12045
SCN4A sodium channel, voltage gated, type IV alpha subunit -9.08114
PLPP3 phospholipid phosphatase 3 -8.98799
TGFBR3 transforming growth factor, beta receptor III -8.96991
CA4 carbonic anhydrase IV -8.85769
PCSK6 proprotein convertase subtilisin/kexin type 6 -8.85103
SRPX2 sushi-repeat containing protein, X-linked 2 -8.85103
ATP10A ATPase, class V, type 10A -8.8307
CAMK1D calcium/calmodulin-dependent protein kinase ID -8.82632
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -8.78274
CCDC69 coiled-coil domain containing 69 -8.75586
CENPN centromere protein N -8.68664
FBLN5 fibulin 5 -8.61769
SGPP1 sphingosine-1-phosphate phosphatase 1 -8.61769
DPH3 diphthamide biosynthesis 3 -8.61769
FBXL7 F-box and leucine-rich repeat protein 7 -8.61325
DIAPH2 diaphanous-related formin 2 -8.6017
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -8.59509
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -8.55904
PI15 peptidase inhibitor 15 -8.53338
ATG9A autophagy related 9A -8.50494
DCLK1 doublecortin-like kinase 1 -8.494
CCDC192 coiled-coil domain containing 192 -8.494
KDM7A-DT KDM7A divergent transcript -8.48847
YPEL2 yippee-like 2 (Drosophila) -8.47384
MYO1B myosin IB -8.46785
MEDAG mesenteric estrogen-dependent adipogenesis -8.43154
PTPRG protein tyrosine phosphatase, receptor type, G -8.41615
ETNPPL ethanolamine-phosphate phospho-lyase -8.40781
CCNA1 cyclin A1 -8.38934
RACGAP1 Rac GTPase activating protein 1 -8.38397
MFGE8 milk fat globule-EGF factor 8 protein -8.37752
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -8.37604
NKIRAS2 NFKB inhibitor interacting Ras-like 2 -8.34244
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing -8.31503
STXBP6 syntaxin binding protein 6 (amisyn) -8.27442
SIRPA signal-regulatory protein alpha -8.26711
IL20RB interleukin 20 receptor beta -8.26388
TESK2 testis-specific kinase 2 -8.26388
LYPD6 LY6/PLAUR domain containing 6 -8.26388
JCAD junctional cadherin 5 associated -8.22913
EMILIN2 elastin microfibril interfacer 2 -8.15823
CPEB4 cytoplasmic polyadenylation element binding protein 4 -8.13099
STARD8 StAR-related lipid transfer (START) domain containing 8 -8.12742
FGFRL1 fibroblast growth factor receptor-like 1 -8.12324
ADO 2-aminoethanethiol (cysteamine) dioxygenase -8.10158
CHEK2 checkpoint kinase 2 -8.09712
SLPI secretory leukocyte peptidase inhibitor -8.09293
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -8.08687
VLDLR very low density lipoprotein receptor -8.08522
LACTB2 lactamase, beta 2 -8.07445
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -8.07445
ERRFI1 ERBB receptor feedback inhibitor 1 -8.03852
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -8.03852
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -8.03852
NINJ2 ninjurin 2 -8.03663
FAM234A family with sequence similarity 234 member A -8.01888
BAG5 BCL2-associated athanogene 5 -7.9327
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -7.9327
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -7.86698
CD38 CD38 molecule -7.8364
EHD2 EH-domain containing 2 -7.8259
COL4A4 collagen, type IV, alpha 4 -7.7985
PHACTR2 phosphatase and actin regulator 2 -7.77036
CAPN11 calpain 11 -7.76154
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -7.74894
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -7.66036
FICD FIC domain containing -7.63973
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene -7.6295
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -7.62611
PLPPR1 phospholipid phosphatase related 1 -7.62291
TMOD1 tropomodulin 1 -7.60622
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -7.59125
RASL10B RAS-like, family 10, member B -7.59125
CDO1 cysteine dioxygenase type 1 -7.5756
PTS 6-pyruvoyltetrahydropterin synthase -7.56873
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 -7.53989
PPL periplakin -7.53419
MYO1D myosin ID -7.51926
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -7.51426
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -7.51169
MTPN myotrophin -7.46516
DEGS1 delta(4)-desaturase, sphingolipid 1 -7.46489
ZDHHC14 zinc finger, DHHC-type containing 14 -7.45306
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -7.42792
GABARAPL1 GABA(A) receptor-associated protein like 1 -7.3921
ACP7 acid phosphatase 7, tartrate resistant (putative) -7.38358
AVEN apoptosis, caspase activation inhibitor -7.37949
MEGF11 multiple EGF-like-domains 11 -7.37678
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -7.36761
ASS1 argininosuccinate synthase 1 -7.36021
RAET1E retinoic acid early transcript 1E -7.3487
TCAIM T cell activation inhibitor, mitochondrial -7.3487
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -7.3487
SQOR sulfide quinone oxidoreductase -7.3456
RGN regucalcin -7.3347
CHP1 calcineurin-like EF-hand protein 1 -7.32039
TMEM150C transmembrane protein 150C -7.30736
PALM paralemmin -7.30336
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -7.26223
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -7.24328
ESRRA estrogen-related receptor alpha -7.18707
VDAC1 voltage-dependent anion channel 1 -7.17468
ARPC5L actin related protein 2/3 complex, subunit 5-like -7.16261
TOR1B torsin family 1, member B (torsin B) -7.15015
MSX1 msh homeobox 1 -7.14936
RASD1 RAS, dexamethasone-induced 1 -7.13809
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -7.12562
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -7.12063
AKR1C1 aldo-keto reductase family 1, member C1 -7.11838
CDK14 cyclin-dependent kinase 14 -7.10699
SERINC3 serine incorporator 3 -7.06921
EBF1 early B-cell factor 1 -7.04585
ATP9A ATPase, class II, type 9A -7.03151
DOCK11 dedicator of cytokinesis 11 -7.00246
PRDX6 peroxiredoxin 6 -7.00145
OSTM1 osteopetrosis associated transmembrane protein 1 -6.97784
FILIP1 filamin A interacting protein 1 -6.97784
PEDS1 plasmanylethanolamine desaturase 1 -6.97723
MLIP muscular LMNA-interacting protein -6.96242
TPST2 tyrosylprotein sulfotransferase 2 -6.93555
HAGH hydroxyacylglutathione hydrolase -6.93545
MTARC1 mitochondrial amidoxime reducing component 1 -6.92839
HIGD2A HIG1 hypoxia inducible domain family, member 2A -6.92243
NPY neuropeptide Y -6.92217
CEMIP2 cell migration inducing hyaluronidase 2 -6.89245
CLEC16A C-type lectin domain family 16, member A -6.888
DERA deoxyribose-phosphate aldolase (putative) -6.888
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -6.888
CAV2 caveolin 2 -6.88421
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -6.86532
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 -6.85688
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -6.84919
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) -6.84649
CTIF CBP80/20-dependent translation initiation factor -6.8458
SSTR2 somatostatin receptor 2 -6.8458
ACSL1 acyl-CoA synthetase long-chain family member 1 -6.83685
LIMCH1 LIM and calponin homology domains 1 -6.83563
MMP3 matrix metallopeptidase 3 -6.83064
SELENOS selenoprotein S -6.81953
SPTB spectrin, beta, erythrocytic -6.79961
PAM peptidylglycine alpha-amidating monooxygenase -6.79208
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 -6.7795
STMP1 short transmembrane mitochondrial protein 1 -6.77767
PKN3 protein kinase N3 -6.75377
RANBP17 RAN binding protein 17 -6.7528
PDE4A phosphodiesterase 4A, cAMP-specific -6.75144
KIF3B kinesin family member 3B -6.74571
MGST2 microsomal glutathione S-transferase 2 -6.7386
PCDH18 protocadherin 18 -6.73628
BBLN bublin coiled coil protein -6.71705
MPZL1 myelin protein zero-like 1 -6.71705
TBX3 T-box 3 -6.71398
E2F6 E2F transcription factor 6 -6.70789
NFYB nuclear transcription factor Y, beta -6.70776
PRR5 proline rich 5 (renal) -6.70461
MSRA methionine sulfoxide reductase A -6.68792
ANXA4 annexin A4 -6.68617
TSPAN4 tetraspanin 4 -6.68501
CD36 CD36 molecule (thrombospondin receptor) -6.68501
SLC35F6 solute carrier family 35, member F6 -6.68501
FZD5 frizzled class receptor 5 -6.67809
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -6.66883
MAOA monoamine oxidase A -6.65843
ELANE elastase, neutrophil expressed -6.65513
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -6.64318
CLDN12 claudin 12 -6.64293
EDARADD EDAR-associated death domain -6.63347
CDYL2 chromodomain protein, Y-like 2 -6.63011
KRT17 keratin 17, type I -6.62657
SRL sarcalumenin -6.62657
AK4 adenylate kinase 4 -6.62305
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -6.60482
CHRDL1 chordin-like 1 -6.59944
DERL1 derlin 1 -6.5994
MTCH2 mitochondrial carrier 2 -6.59687
FGL2 fibrinogen-like 2 -6.58361
DIRAS2 DIRAS family, GTP-binding RAS-like 2 -6.58361
RTN4 reticulon 4 -6.5721
FABP4 fatty acid binding protein 4, adipocyte -6.56948
YBX2 Y box binding protein 2 -6.56684
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -6.54313
SUCNR1 succinate receptor 1 -6.53795
PRADC1 protease-associated domain containing 1 -6.53795
P3H2 prolyl 3-hydroxylase 2 -6.52256
TJP2 tight junction protein 2 -6.52256
SIAH2 siah E3 ubiquitin protein ligase 2 -6.52256
DLD dihydrolipoamide dehydrogenase -6.52256