GTEx Testis 20-29 vs 50-59 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

65 genes with high or low expression in GTEx Testis 20-29 vs 50-59 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
PTCHD4 patched domain containing 4 27.8829
CXCL13 chemokine (C-X-C motif) ligand 13 6.97348
COL4A6 collagen, type IV, alpha 6 6.4088
NALCN sodium leak channel, non selective 6.32055
MFAP5 microfibrillar associated protein 5 5.51606
EDA2R ectodysplasin A2 receptor 5.3071
C16ORF89 chromosome 16 open reading frame 89 4.90758
LTBP2 latent transforming growth factor beta binding protein 2 4.73189
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 4.4115
RSAD2 radical S-adenosyl methionine domain containing 2 4.4115
PHLDA3 pleckstrin homology-like domain, family A, member 3 4.4115
ADAMTSL2 ADAMTS-like 2 4.4115
GRTP1 growth hormone regulated TBC protein 1 4.4115
KLHDC8A kelch domain containing 8A 4.4115
SFRP2 secreted frizzled-related protein 2 4.4115
IFI44L interferon-induced protein 44-like 4.4115
XAF1 XIAP associated factor 1 4.41071
TPSG1 tryptase gamma 1 4.24545
HAUS7 HAUS augmin-like complex, subunit 7 4.20453
CYS1 cystin 1 4.20453
OBSCN-AS1 OBSCN antisense RNA 1 4.10567
CD69 CD69 molecule 4.09353
MFAP4 microfibrillar-associated protein 4 3.99916
HTRA1 HtrA serine peptidase 1 3.99916
TMEM119 transmembrane protein 119 3.99916
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 3.99916
COL16A1 collagen, type XVI, alpha 1 3.90363
SELENOO selenoprotein O 3.89134
VWCE von Willebrand factor C and EGF domains 3.88132
GREM2 gremlin 2, DAN family BMP antagonist 3.84687
ACTA2-AS1 ACTA2 antisense RNA 1 3.84687
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 3.81784
CMKLR1 chemerin chemokine-like receptor 1 3.81784
IL15 interleukin 15 3.71524
IL17REL interleukin 17 receptor E-like 3.6713
HCST hematopoietic cell signal transducer 3.6713
TM4SF18 transmembrane 4 L six family member 18 3.66708
ZMAT3 zinc finger, matrin-type 3 3.66708
DPEP1 dipeptidase 1 (renal) 3.66708
LMO3 LIM domain only 3 (rhombotin-like 2) 3.66708
ERICH1 glutamate-rich 1 3.65744
MEOX1 mesenchyme homeobox 1 3.36714
MRC2 mannose receptor, C type 2 3.32786
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 3.31955
C11ORF21 chromosome 11 open reading frame 21 3.30064
LINC02898 long intergenic non-protein coding RNA 2898 3.25301
WNT4 wingless-type MMTV integration site family, member 4 3.25301
KIAA1755 KIAA1755 3.23585
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 3.23585
LAG3 lymphocyte-activation gene 3 3.23585
AEBP1 AE binding protein 1 3.23585
ACSBG1 acyl-CoA synthetase bubblegum family member 1 3.20161
LAMC3 laminin, gamma 3 3.13387
CBLN4 cerebellin 4 precursor 3.06426
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 3.02103
PDE5A phosphodiesterase 5A, cGMP-specific 3.01025
PON1 paraoxonase 1 3.01025

decreased expression

Symbol Name Standardized Value
ZNF93 zinc finger protein 93 -6.47686
VLDLR very low density lipoprotein receptor -4.53138
LINC00911 long intergenic non-protein coding RNA 911 -4.4115
LOC102724710 uncharacterized LOC102724710 -4.4115
IRF2-DT IRF2 divergent transcript -4.2864
ADGRL3 adhesion G protein-coupled receptor L3 -4.16088
AMPH amphiphysin -3.84687
ELSPBP1 epididymal sperm binding protein 1 -3.23585