GTEx Thyroid 20-29 vs 50-59 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

499 genes with high or low expression in GTEx Thyroid 20-29 vs 50-59 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
LIPI lipase, member I 11.2048
PTCHD4 patched domain containing 4 11.0617
DAPL1 death associated protein-like 1 9.78111
RORB RAR-related orphan receptor B 8.93425
EYA4 EYA transcriptional coactivator and phosphatase 4 8.93386
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 7.8845
HSF4 heat shock transcription factor 4 7.86485
HSPA1B heat shock 70kDa protein 1B 7.77967
STPG2 sperm-tail PG-rich repeat containing 2 7.6557
FAM185A family with sequence similarity 185, member A 7.6557
BMPR1B bone morphogenetic protein receptor, type IB 7.62749
EPHA10 EPH receptor A10 7.62749
POU2AF3 POU class 2 homeobox associating factor 3 7.61977
KRBOX4 KRAB box domain containing 4 7.61977
GATA5 GATA binding protein 5 7.25697
ZFHX2 zinc finger homeobox 2 7.25697
CCDC148 coiled-coil domain containing 148 7.15812
SHROOM1 shroom family member 1 7.10119
CEP57L1 centrosomal protein 57kDa-like 1 7.00691
MAT1A methionine adenosyltransferase I, alpha 6.96864
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 6.82624
ESR1 estrogen receptor 1 6.82624
HSPA6 heat shock 70kDa protein 6 (HSP70B') 6.76213
PAH phenylalanine hydroxylase 6.76213
C16ORF89 chromosome 16 open reading frame 89 6.72157
GDF15 growth differentiation factor 15 6.6645
H2BC18 H2B clustered histone 18 6.64631
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 6.47282
FHIP1B FHF complex subunit HOOK interacting protein 1B 6.4727
THBS3 thrombospondin 3 6.4698
SPATA18 spermatogenesis associated 18 6.4519
MEF2C-AS1 MEF2C antisense RNA 1 6.41838
HSPA1A heat shock 70kDa protein 1A 6.41425
LRRC37A17P leucine rich repeat containing 37, member A17, pseudogene 6.36891
PCED1A PC-esterase domain containing 1A 6.31224
HSPA7 heat shock 70kDa protein 7 (HSP70B) 6.2409
ZMAT3 zinc finger, matrin-type 3 6.2046
PRR29-AS1 PRR29 antisense RNA 1 6.19263
ECHDC2 enoyl CoA hydratase domain containing 2 6.15447
TCIM transcriptional and immune response regulator 6.08364
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 6.08364
CASP9 caspase 9, apoptosis-related cysteine peptidase 6.08364
NKAIN4 Na+/K+ transporting ATPase interacting 4 6.08364
COLCA1 colorectal cancer associated 1 6.08364
SMOC2 SPARC related modular calcium binding 2 6.08364
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 6.08364
DZIP3 DAZ interacting zinc finger protein 3 6.08364
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 6.08364
RYR2 ryanodine receptor 2 (cardiac) 6.08364
SPEF2 sperm flagellar 2 6.05538
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 6.02771
MAN1C1 mannosidase, alpha, class 1C, member 1 5.97961
ANKRD24 ankyrin repeat domain 24 5.97961
PLCD4 phospholipase C, delta 4 5.96226
POGZ pogo transposable element with ZNF domain 5.96226
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 5.94121
POLL polymerase (DNA directed), lambda 5.86364
LOC100130691 uncharacterized LOC100130691 5.81778
FBXO15 F-box protein 15 5.81778
ZNF460 zinc finger protein 460 5.81774
VEPH1 ventricular zone expressed PH domain-containing 1 5.78977
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 5.71738
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 5.70011
TTC14 tetratricopeptide repeat domain 14 5.68022
LINC00174 long intergenic non-protein coding RNA 174 5.68022
DOC2A double C2-like domains, alpha 5.64231
ANKRD18A ankyrin repeat domain 18A 5.64231
HADHAP1 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 1 5.64231
EFCAB6 EF-hand calcium binding domain 6 5.62874
LINC02102 long intergenic non-protein coding RNA 2102 5.59884
CRMP1 collapsin response mediator protein 1 5.59277
RPL4P6 ribosomal protein L4 pseudogene 6 5.59277
STX16 syntaxin 16 5.58285
LMNTD2-AS1 LMNTD2 antisense RNA 1 5.57676
TSPEAR thrombospondin-type laminin G domain and EAR repeats 5.57376
NKX2-8 NK2 homeobox 8 5.57375
OTOS otospiralin 5.57375
PTPRG-AS1 PTPRG antisense RNA 1 5.54068
RGS11 regulator of G-protein signaling 11 5.52185
CCN1 cellular communication network factor 1 5.52185
CCDC154 coiled-coil domain containing 154 5.52185
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 5.52185
CEROX1 cytoplasmic endogenous regulator of oxidative phosphorylation 1 5.51951
ANKRD37 ankyrin repeat domain 37 5.5065
SOD3 superoxide dismutase 3, extracellular 5.49486
CLIC6 chloride intracellular channel 6 5.49486
SUMO4 small ubiquitin-like modifier 4 5.49486
MAP3K12 mitogen-activated protein kinase kinase kinase 12 5.49486
PKN2-AS1 PKN2 antisense RNA 1 5.49486
PPP1R15A protein phosphatase 1, regulatory subunit 15A 5.49486
LINC01354 long intergenic non-protein coding RNA 1354 5.49486
CATIP ciliogenesis associated TTC17 interacting protein 5.49486
COX10-DT COX10 divergent transcript 5.49299
SMIM14-DT SMIM14 divergent transcript 5.49299
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 5.49299
EGFR-AS1 EGFR antisense RNA 1 5.48259
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 5.4812
CEP162 centrosomal protein 162kDa 5.4812
ODAD2 outer dynein arm docking complex subunit 2 5.47864
RANBP10 RAN binding protein 10 5.47663
SLITRK5 SLIT and NTRK-like family, member 5 5.47591
FAM27E3 family with sequence similarity 27, member E3 5.42595
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 5.42394
LAS1L LAS1-like (S. cerevisiae) 5.42345
CCDC171 coiled-coil domain containing 171 5.39065
EPHA5-AS1 EPHA5 antisense RNA 1 5.39065
RUFY1-AS1 RUFY1 antisense RNA 1 5.38501
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 5.36966
ERI2 ERI1 exoribonuclease family member 2 5.36599
ECRG4 ECRG4 augurin precursor 5.36217
MYCBPAP MYCBP associated protein 5.36217
SMCO3 single-pass membrane protein with coiled-coil domains 3 5.32247
DUSP13B dual specificity phosphatase 13B 5.31041
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 5.29997
SPDYA speedy/RINGO cell cycle regulator family member A 5.29405
ATF3 activating transcription factor 3 5.26161
ZNF528 zinc finger protein 528 5.25847
HYMAI hydatidiform mole associated and imprinted (non-protein coding) 5.25847
JUN jun proto-oncogene 5.2514
CACTIN cactin, spliceosome C complex subunit 5.2514
CCDC28A-AS1 CCDC28A antisense RNA 1 5.2514
TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 5.2514
ADAM33 ADAM metallopeptidase domain 33 5.24879
LCN12 lipocalin 12 5.2368
CPEB1 cytoplasmic polyadenylation element binding protein 1 5.2368
AFAP1-AS1 AFAP1 antisense RNA 1 5.2037
ERC2 ELKS/RAB6-interacting/CAST family member 2 5.2037
ZNF718 zinc finger protein 718 5.19181
TMEM232 transmembrane protein 232 5.17227
RPL13AP12 ribosomal protein L13a pseudogene 12 5.14404
ZNF780B zinc finger protein 780B 5.12747
PCSK4 proprotein convertase subtilisin/kexin type 4 5.12747
USP3-AS1 USP3 antisense RNA 1 5.12399
BHLHE40 basic helix-loop-helix family, member e40 5.12399
MIF4GD-DT MIF4GD divergent transcript 5.12399
CENPP centromere protein P 5.12399
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 5.12399
CSAD cysteine sulfinic acid decarboxylase 5.12399
MCF2 MCF.2 cell line derived transforming sequence 5.12399
VN1R108P vomeronasal 1 receptor 108 pseudogene 5.12399
ASTN2 astrotactin 2 5.12341
INTU inturned planar cell polarity protein 5.12341
INVS inversin 5.11151
LRRC37A3 leucine rich repeat containing 37, member A3 5.11151
ECM1 extracellular matrix protein 1 5.10526
DGKB diacylglycerol kinase, beta 90kDa 5.10526
BHLHE40-AS1 BHLHE40 antisense RNA 1 5.09937
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 5.09937
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 5.09937
KIAA0753 KIAA0753 5.09361
PCP2 Purkinje cell protein 2 5.09361
DNAH7 dynein, axonemal, heavy chain 7 5.09097
CADM2 cell adhesion molecule 2 5.08317
MPPED2 metallophosphoesterase domain containing 2 5.07132
GRIP2 glutamate receptor interacting protein 2 5.06164
CRYGN crystallin, gamma N 5.06019
UBQLN1-AS1 UBQLN1 antisense RNA 1 5.03761
POT1-AS1 POT1 antisense RNA 1 5.03416
WDFY3-AS2 WDFY3 antisense RNA 2 5.03243
KAT2A K(lysine) acetyltransferase 2A 5.01557
DM1-AS DM1 locus antisense RNA 4.99852
TOP1MT topoisomerase (DNA) I, mitochondrial 4.99852
CCDC30 coiled-coil domain containing 30 4.99852
CNGA4 cyclic nucleotide gated channel alpha 4 4.99852
SPTBN4 spectrin, beta, non-erythrocytic 4 4.99533
CEP112 centrosomal protein 112kDa 4.97869
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J 4.96022
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 4.96022
GYS2 glycogen synthase 2 (liver) 4.95582
ZNF793 zinc finger protein 793 4.93667
MANEAL mannosidase, endo-alpha-like 4.93667
C12ORF60 chromosome 12 open reading frame 60 4.92787
ITGA9-AS1 ITGA9 antisense RNA 1 4.92658
PPP1R3E protein phosphatase 1, regulatory subunit 3E 4.92658
C19ORF44 chromosome 19 open reading frame 44 4.92658
ZEB1-AS1 ZEB1 antisense RNA 1 4.91087
SPAG8 sperm associated antigen 8 4.89342
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 4.88524
DNASE1L2 deoxyribonuclease I-like 2 4.87279
BBS9 Bardet-Biedl syndrome 9 4.84361
GSTM2 glutathione S-transferase mu 2 (muscle) 4.83974
CPXM2 carboxypeptidase X (M14 family), member 2 4.83974
SLC25A27 solute carrier family 25, member 27 4.8151
ZFP36 ZFP36 ring finger protein 4.78777
DCT dopachrome tautomerase 4.78525
ZFP62 ZFP62 zinc finger protein 4.78238
GABPB2 GA binding protein transcription factor, beta subunit 2 4.7734
MIRLET7IHG MIRLET7I host gene 4.7734
ZMAT1 zinc finger, matrin-type 1 4.7734
HYDIN HYDIN, axonemal central pair apparatus protein 4.75013
ATP2C2-AS1 ATP2C2 antisense RNA 1 4.74567
TK2 thymidine kinase 2, mitochondrial 4.72884
AP3B2 adaptor-related protein complex 3, beta 2 subunit 4.72081
LOC105375166 uncharacterized LOC105375166 4.71799
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 4.71088
COL22A1 collagen, type XXII, alpha 1 4.702
CFAP61 cilia and flagella associated protein 61 4.702
LINC01814 long intergenic non-protein coding RNA 1814 4.702
LOC100506235 uncharacterized LOC100506235 4.702
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 4.702
GAMT guanidinoacetate N-methyltransferase 4.702
TMEM178A transmembrane protein 178A 4.68141
AMT aminomethyltransferase 4.6652
EPHA6 EPH receptor A6 4.63249
STC1 stanniocalcin 1 4.63249
SCN2B sodium channel, voltage gated, type II beta subunit 4.63249
TMEM25 transmembrane protein 25 4.61599
SCML2 sex comb on midleg-like 2 (Drosophila) 4.61543
FOS FBJ murine osteosarcoma viral oncogene homolog 4.60799
LINC00886 long intergenic non-protein coding RNA 886 4.60799
DNASE1 deoxyribonuclease I 4.60799
PDCD6IP-DT PDCD6IP divergent transcript 4.60799
EPHA5 EPH receptor A5 4.59703
RCCD1 RCC1 domain containing 1 4.59629
EDA2R ectodysplasin A2 receptor 4.59629
TBX6 T-box 6 4.5919
LINC02762 long intergenic non-protein coding RNA 2762 4.5919
CSP2 CS pseudogene 2 4.58817
RBM19 RNA binding motif protein 19 4.58712
LOC105370047 uncharacterized LOC105370047 4.58588
FGF9 fibroblast growth factor 9 4.57603
ULK4 unc-51 like kinase 4 4.57173
UBE3B ubiquitin protein ligase E3B 4.57162
CELF6 CUGBP, Elav-like family member 6 4.55965
MIR3677HG MIR3677 and MIR940 host gene 4.55948
PTN pleiotrophin 4.55948
FAS Fas cell surface death receptor 4.55948
ERICH2-DT ERICH2 divergent transcript 4.55948
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 4.55563
DNAJC27-AS1 DNAJC27 antisense RNA 1 4.54312
LMNTD2 lamin tail domain containing 2 4.54127
CTBP1 C-terminal binding protein 1 4.5386
DUXAP8 double homeobox A pseudogene 8 4.52381
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 4.52381
CASC2 cancer susceptibility candidate 2 (non-protein coding) 4.52157
FOXP1-DT FOXP1 divergent transcript 4.52157
NRXN2 neurexin 2 4.52042
CDC20-DT CDC20 divergent transcript 4.4965
THBS3-AS1 THBS3 antisense RNA 1 4.49624
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) 4.49129
MELTF-AS1 MELTF antisense RNA 1 4.47706
CHROMR cholesterol induced regulator of metabolism RNA 4.47061
ANKRD31 ankyrin repeat domain 31 4.46747
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 4.46747
KLHL3 kelch-like family member 3 4.46747
TAS2R19 taste receptor, type 2, member 19 4.46747
UBC ubiquitin C 4.45941
NRXN3 neurexin 3 4.45941
PRRT2 proline-rich transmembrane protein 2 4.45941

decreased expression

Symbol Name Standardized Value
ZNF518B zinc finger protein 518B -11.2048
GIMAP6 GTPase, IMAP family member 6 -8.93425
CLP1 cleavage and polyadenylation factor I subunit 1 -8.93425
PHETA2 PH domain containing endocytic trafficking adaptor 2 -8.93425
GIMAP7 GTPase, IMAP family member 7 -7.82726
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -7.82726
GMPS guanine monphosphate synthase -7.79317
ABT1 activator of basal transcription 1 -7.6557
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -7.6557
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) -7.6557
RFLNB refilin B -7.6557
HPS6 Hermansky-Pudlak syndrome 6 -7.62749
UBP1 upstream binding protein 1 (LBP-1a) -7.62749
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -7.62749
ZNF792 zinc finger protein 792 -7.62749
CUTC cutC copper transporter -7.61977
TUBA1C tubulin, alpha 1c -7.61977
FAM110D family with sequence similarity 110, member D -7.61977
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 -7.61977
NOL11 nucleolar protein 11 -7.61977
PLRG1 pleiotropic regulator 1 -7.50222
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -7.25791
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -7.25791
RRAGA Ras-related GTP binding A -7.23642
KDM1A lysine (K)-specific demethylase 1A -7.17238
GIMAP4 GTPase, IMAP family member 4 -7.15812
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -7.10119
TRIM13 tripartite motif containing 13 -6.96864
INKA2 inka box actin regulator 2 -6.92906
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -6.90679
FEN1 flap structure-specific endonuclease 1 -6.76213
ELOVL1 ELOVL fatty acid elongase 1 -6.76213
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -6.76213
TFRC transferrin receptor -6.76213
USP10 ubiquitin specific peptidase 10 -6.76213
CCNE1 cyclin E1 -6.72157
FAF2 Fas associated factor family member 2 -6.72157
BUD13 BUD13 homolog (S. cerevisiae) -6.6761
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -6.6645
BLMH bleomycin hydrolase -6.63254
RPUSD2 RNA pseudouridylate synthase domain containing 2 -6.53446
EPHB4 EPH receptor B4 -6.41838
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -6.39196
TRIM24 tripartite motif containing 24 -6.34738
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -6.34168
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -6.27906
VIRMA vir like m6A methyltransferase associated -6.27906
AKAP8 A kinase (PRKA) anchor protein 8 -6.26288
PWP1 PWP1 homolog (S. cerevisiae) -6.2409
CHPF2 chondroitin polymerizing factor 2 -6.22052
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -6.15447
ABRAXAS2 abraxas 2, BRISC complex subunit -6.08364
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -6.08364
UBASH3B ubiquitin associated and SH3 domain containing B -6.08364
QRICH1 glutamine-rich 1 -6.08364
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -6.08364
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -6.08364
GIMAP1 GTPase, IMAP family member 1 -6.08364
C6ORF47 chromosome 6 open reading frame 47 -6.08364
MCMBP minichromosome maintenance complex binding protein -6.06
TUBB4B tubulin, beta 4B class IVb -6.00022
GPAT4 glycerol-3-phosphate acyltransferase 4 -5.97961
CIAPIN1 cytokine induced apoptosis inhibitor 1 -5.97961
ELOA elongin A -5.96226
UBE2K ubiquitin-conjugating enzyme E2K -5.96226
INTS14 integrator complex subunit 14 -5.96226
LRR1 leucine rich repeat protein 1 -5.81778
CCNJ cyclin J -5.81778
RARS1 arginyl-tRNA synthetase 1 -5.81778
ZNF747 zinc finger protein 747 -5.81778
RIOK2 RIO kinase 2 -5.81774
WBP1L WW domain binding protein 1-like -5.8103
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -5.79963
CBX6 chromobox homolog 6 -5.79444
ADPRH ADP-ribosylarginine hydrolase -5.76444
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -5.76299
NUP133 nucleoporin 133kDa -5.7341
MAD2L1BP MAD2L1 binding protein -5.7341
ATMIN ATM interactor -5.70514
ECE1 endothelin converting enzyme 1 -5.70356
NCOA4 nuclear receptor coactivator 4 -5.70333
TP53RK TP53 regulating kinase -5.68022
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -5.68022
HYAL1 hyaluronoglucosaminidase 1 -5.68022
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -5.67715
MYD88 myeloid differentiation primary response 88 -5.64231
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -5.64231
RBBP4 retinoblastoma binding protein 4 -5.64231
RBM15B RNA binding motif protein 15B -5.64231
SSTR2 somatostatin receptor 2 -5.64231
CDC42 cell division cycle 42 -5.64231
PRDX1 peroxiredoxin 1 -5.64231
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -5.64231
TUBB tubulin, beta class I -5.64231
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -5.64231
EFTUD2 elongation factor Tu GTP binding domain containing 2 -5.64231
MOB4 MOB family member 4, phocein -5.64231
MIF4GD MIF4G domain containing -5.62874
SNIP1 Smad nuclear interacting protein 1 -5.62874
NEPRO nucleolus and neural progenitor protein -5.6229
FAM43A family with sequence similarity 43, member A -5.6116
COP1 COP1 E3 ubiquitin ligase -5.61048
FZD10 frizzled class receptor 10 -5.6085
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -5.59884
ZNF629 zinc finger protein 629 -5.59884
MIR22HG MIR22 host gene -5.5983
BAZ1B bromodomain adjacent to zinc finger domain, 1B -5.5983
GLUD2 glutamate dehydrogenase 2 -5.58728
NANP N-acetylneuraminic acid phosphatase -5.57676
PRKCH protein kinase C, eta -5.57676
KIAA0232 KIAA0232 -5.57676
NKAPL NFKB activating protein-like -5.57375
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -5.56989
HSPA14 heat shock 70kDa protein 14 -5.56832
TBK1 TANK-binding kinase 1 -5.56832
RPA1 replication protein A1, 70kDa -5.54068
COA7 cytochrome c oxidase assembly factor 7 (putative) -5.53494
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -5.52185
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -5.52185
C14ORF119 chromosome 14 open reading frame 119 -5.52185
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -5.52185
GSPT2 G1 to S phase transition 2 -5.49572
E2F6 E2F transcription factor 6 -5.49486
NT5DC2 5'-nucleotidase domain containing 2 -5.49486
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -5.49486
RRP1B ribosomal RNA processing 1B -5.49486
DOLK dolichol kinase -5.49486
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) -5.49486
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -5.49486
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -5.49486
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -5.49486
RBIS ribosomal biogenesis factor -5.49299
C5ORF22 chromosome 5 open reading frame 22 -5.49299
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -5.49299
SPRTN SprT-like N-terminal domain -5.4773
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -5.4773
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -5.47663
VEGFD vascular endothelial growth factor D -5.47582
COIL coilin -5.47582
CCNYL1 cyclin Y-like 1 -5.42394
NECTIN1 nectin cell adhesion molecule 1 -5.39945
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -5.39065
MRPS22 mitochondrial ribosomal protein S22 -5.39065
AXL AXL receptor tyrosine kinase -5.39065
GIMAP8 GTPase, IMAP family member 8 -5.39065
PCGF6 polycomb group ring finger 6 -5.39065
KCTD20 potassium channel tetramerization domain containing 20 -5.39065
TRNAU1AP tRNA selenocysteine 1 associated protein 1 -5.38651
KEAP1 kelch-like ECH-associated protein 1 -5.38501
PPP4R1 protein phosphatase 4, regulatory subunit 1 -5.36217
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -5.35787
TPP2 tripeptidyl peptidase II -5.31497
EID2 EP300 interacting inhibitor of differentiation 2 -5.31389
PLAA phospholipase A2-activating protein -5.31354
ACOT9 acyl-CoA thioesterase 9 -5.31041
MRPS18C mitochondrial ribosomal protein S18C -5.28151
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -5.27159
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -5.26161
TSKU tsukushi, small leucine rich proteoglycan -5.2514
ZNF587B zinc finger protein 587B -5.2514
RANBP17 RAN binding protein 17 -5.2514
GYPE glycophorin E (MNS blood group) -5.2514
SH3GLB1 SH3-domain GRB2-like endophilin B1 -5.2514
ENY2 enhancer of yellow 2 homolog (Drosophila) -5.2514
VCP valosin containing protein -5.25057
ACAT2 acetyl-CoA acetyltransferase 2 -5.24879
PDHB pyruvate dehydrogenase (lipoamide) beta -5.24879
ZBTB39 zinc finger and BTB domain containing 39 -5.2368
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -5.2037
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -5.19446
NPAT nuclear protein, ataxia-telangiectasia locus -5.18342
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -5.1593
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -5.12747
AAGAB alpha- and gamma-adaptin binding protein -5.12747
MACROH2A1 macroH2A.1 histone -5.12399
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -5.12399
MRPL46 mitochondrial ribosomal protein L46 -5.12399
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -5.10526
MIEF1 mitochondrial elongation factor 1 -5.10526
KIFBP kinesin family binding protein -5.10526
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -5.10526
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -5.10526
GLRX3 glutaredoxin 3 -5.10526
LCMT2 leucine carboxyl methyltransferase 2 -5.09328
IRAK1 interleukin-1 receptor-associated kinase 1 -5.09097
TXNRD1 thioredoxin reductase 1 -5.08673
ACTL6A actin-like 6A -5.08673
POLR1F RNA polymerase I subunit F -5.08673
CASP2 caspase 2, apoptosis-related cysteine peptidase -5.0481
GSPT1 G1 to S phase transition 1 -5.03347
GSK3B glycogen synthase kinase 3 beta -5.03243
CD300LG CD300 molecule-like family member g -5.03243
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -5.03243
PRCC papillary renal cell carcinoma (translocation-associated) -5.03243
ADGRG2 adhesion G protein-coupled receptor G2 -5.0315
VPS26C VPS26 endosomal protein sorting factor C -5.02548
DSN1 DSN1, MIS12 kinetochore complex component -5.01557
ZBTB6 zinc finger and BTB domain containing 6 -5.00595
SRP72 signal recognition particle 72kDa -4.99852
PSEN1 presenilin 1 -4.99852
HK1 hexokinase 1 -4.99808
UBE2N ubiquitin-conjugating enzyme E2N -4.97869
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -4.97843
NIP7 NIP7, nucleolar pre-rRNA processing protein -4.97457
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -4.97192
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -4.96265
GAR1 GAR1 ribonucleoprotein -4.96022
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -4.95989
ANKLE2 ankyrin repeat and LEM domain containing 2 -4.95655
ILF2 interleukin enhancer binding factor 2 -4.93096
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -4.93096
OLFM2 olfactomedin 2 -4.92658
GJA4 gap junction protein, alpha 4, 37kDa -4.91932
USP16 ubiquitin specific peptidase 16 -4.91932
TXNDC9 thioredoxin domain containing 9 -4.9112
PPP1R8 protein phosphatase 1, regulatory subunit 8 -4.91068
XPR1 xenotropic and polytropic retrovirus receptor 1 -4.89342
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -4.89342
BLVRA biliverdin reductase A -4.89342
SZRD1 SUZ RNA binding domain containing 1 -4.89342
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -4.89342
FBXO38 F-box protein 38 -4.89342
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -4.89342
EPHB2 EPH receptor B2 -4.88524
ASB8 ankyrin repeat and SOCS box containing 8 -4.87584
SF3A3 splicing factor 3a, subunit 3, 60kDa -4.86091
WDR77 WD repeat domain 77 -4.85681
ELAC2 elaC ribonuclease Z 2 -4.84841
SELENOI selenoprotein I -4.83974
HEYL hes-related family bHLH transcription factor with YRPW motif-like -4.82527
OSGIN1 oxidative stress induced growth inhibitor 1 -4.8151
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -4.79606
CARD6 caspase recruitment domain family, member 6 -4.79463
RTL9 retrotransposon Gag like 9 -4.78887
LRRC42 leucine rich repeat containing 42 -4.78777
FDPS farnesyl diphosphate synthase -4.78525
CNOT11 CCR4-NOT transcription complex, subunit 11 -4.78525
DUTP6 deoxyuridine triphosphatase pseudogene 6 -4.78525
GSR glutathione reductase -4.78238
BCL9 B-cell CLL/lymphoma 9 -4.78238
EIF3B eukaryotic translation initiation factor 3, subunit B -4.77794
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -4.77794
FASTKD5 FAST kinase domains 5 -4.7734
GRAP GRB2-related adaptor protein -4.76701
GORASP2 golgi reassembly stacking protein 2, 55kDa -4.76701
TMEM102 transmembrane protein 102 -4.75101
NKIRAS2 NFKB inhibitor interacting Ras-like 2 -4.75013
PPARG peroxisome proliferator-activated receptor gamma -4.75013
SHLD2 shieldin complex subunit 2 -4.75013
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -4.74841