GTEx Thyroid 20-29 vs 60-69 Gene Set

Dataset GTEx Tissue-Specific Aging Signatures
Category transcriptomics
Type tissue sample
Description aging signature described by "GTEx [Tissue] [Background Age] vs [Sample Age]" (Genotype Tissue Expression)
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Genes

500 genes with high or low expression in GTEx Thyroid 20-29 vs 60-69 relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset.

increased expression

Symbol Name Standardized Value
RORB RAR-related orphan receptor B 22.8995
PTCHD4 patched domain containing 4 17.2493
GDF15 growth differentiation factor 15 16.6723
EPHA10 EPH receptor A10 14.3099
BMPR1B bone morphogenetic protein receptor, type IB 14.0881
HBA2 hemoglobin, alpha 2 13.7502
EYA4 EYA transcriptional coactivator and phosphatase 4 13.7123
NTF4 neurotrophin 4 13.6494
SPATA18 spermatogenesis associated 18 13.5215
HSPA1B heat shock 70kDa protein 1B 13.0023
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 12.9743
TCIM transcriptional and immune response regulator 12.4016
GATA5 GATA binding protein 5 12.3752
HSF4 heat shock transcription factor 4 12.3752
HBB hemoglobin, beta 11.9114
ANKRD37 ankyrin repeat domain 37 11.7097
ZMAT3 zinc finger, matrin-type 3 11.4347
HSPA1A heat shock 70kDa protein 1A 10.7619
ATF3 activating transcription factor 3 10.7516
CCN1 cellular communication network factor 1 10.5736
SMCO3 single-pass membrane protein with coiled-coil domains 3 10.5536
H2BC18 H2B clustered histone 18 10.4453
BHLHE40 basic helix-loop-helix family, member e40 10.2992
CCDC148 coiled-coil domain containing 148 10.1971
STC1 stanniocalcin 1 10.1437
SUMO4 small ubiquitin-like modifier 4 9.97592
HSPA6 heat shock 70kDa protein 6 (HSP70B') 9.78084
CADM2 cell adhesion molecule 2 9.76182
LEPR leptin receptor 9.74439
UPK3BP1 uroplakin 3B pseudogene 1 9.73732
RCCD1 RCC1 domain containing 1 9.54833
STPG2 sperm-tail PG-rich repeat containing 2 9.53319
PBX3 pre-B-cell leukemia homeobox 3 9.51814
ZFP36 ZFP36 ring finger protein 9.38025
PPP1R15A protein phosphatase 1, regulatory subunit 15A 9.35065
MCF2 MCF.2 cell line derived transforming sequence 9.34465
MAN1C1 mannosidase, alpha, class 1C, member 1 9.3391
CEP57L1 centrosomal protein 57kDa-like 1 9.29724
ALAS2 5'-aminolevulinate synthase 2 9.29196
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 9.29176
HBA1 hemoglobin, alpha 1 9.27162
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 9.14349
SOAT2 sterol O-acyltransferase 2 8.96959
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 8.9209
TTC14 tetratricopeptide repeat domain 14 8.90092
KRTAP5-1 keratin associated protein 5-1 8.86233
HBEGF heparin-binding EGF-like growth factor 8.84619
LINC01354 long intergenic non-protein coding RNA 1354 8.82303
FAM185A family with sequence similarity 185, member A 8.73647
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 8.64793
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 8.64791
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 8.57361
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 8.56384
SPIN4 spindlin family, member 4 8.472
SRSF5 serine/arginine-rich splicing factor 5 8.47098
IER5L immediate early response 5-like 8.42037
MYH15 myosin, heavy chain 15 8.39741
IVNS1ABP influenza virus NS1A binding protein 8.39741
HADHAP1 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 1 8.34025
DGKB diacylglycerol kinase, beta 90kDa 8.13969
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 8.11522
LOC102724428 serine/threonine-protein kinase SIK1 8.08214
JUN jun proto-oncogene 8.05037
TMEM178A transmembrane protein 178A 8.05001
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 7.97559
DAPL1 death associated protein-like 1 7.95226
CRABP1 cellular retinoic acid binding protein 1 7.94691
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 7.94691
TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 7.94691
CP ceruloplasmin (ferroxidase) 7.94691
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 7.91196
EDA2R ectodysplasin A2 receptor 7.86119
NUP58 nucleoporin 58 7.81137
VWA5B2 von Willebrand factor A domain containing 5B2 7.81137
H3C10 H3 clustered histone 10 7.7276
KAT2A K(lysine) acetyltransferase 2A 7.71873
DUSP5 dual specificity phosphatase 5 7.69463
ACHE acetylcholinesterase (Yt blood group) 7.67234
APOLD1 apolipoprotein L domain containing 1 7.67009
POU2AF3 POU class 2 homeobox associating factor 3 7.659
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16 7.659
BBS9 Bardet-Biedl syndrome 9 7.6458
FGFR1OP2 FGFR1 oncogene partner 2 7.63643
GCC2-AS1 GCC2 antisense RNA 1 7.60507
NKAIN4 Na+/K+ transporting ATPase interacting 4 7.57016
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 7.53267
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 7.52601
SLC25A27 solute carrier family 25, member 27 7.52601
THBS3 thrombospondin 3 7.51256
SOD3 superoxide dismutase 3, extracellular 7.51256
LINC02539 long intergenic non-protein coding RNA 2539 7.51226
CCDC30 coiled-coil domain containing 30 7.51226
MUC16 mucin 16, cell surface associated 7.48187
CXCL2 chemokine (C-X-C motif) ligand 2 7.47396
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 7.46195
DDIT3 DNA-damage-inducible transcript 3 7.43921
SPDYA speedy/RINGO cell cycle regulator family member A 7.4294
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 7.41484
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 7.41186
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 7.409
PTN pleiotrophin 7.36849
PTPRG-AS1 PTPRG antisense RNA 1 7.36846
INO80E INO80 complex subunit E 7.36727
CA2 carbonic anhydrase II 7.36457
VWA3A von Willebrand factor A domain containing 3A 7.36356
SMOC2 SPARC related modular calcium binding 2 7.35889
EGR3 early growth response 3 7.35002
SYNGR1 synaptogyrin 1 7.35002
ANGPTL5 angiopoietin-like 5 7.33423
CEP170 centrosomal protein 170kDa 7.28922
CEP112 centrosomal protein 112kDa 7.2862
PELI1 pellino E3 ubiquitin protein ligase 1 7.26905
ZNF248 zinc finger protein 248 7.26474
MELTF-AS1 MELTF antisense RNA 1 7.26474
KIAA0753 KIAA0753 7.26474
TREM1 triggering receptor expressed on myeloid cells 1 7.24246
RANBP10 RAN binding protein 10 7.23251
DUXAP8 double homeobox A pseudogene 8 7.23251
CRMP1 collapsin response mediator protein 1 7.23251
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 7.22732
CXCL8 chemokine (C-X-C motif) ligand 8 7.21223
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 7.19398
TNK2 tyrosine kinase, non-receptor, 2 7.19398
DLL4 delta-like 4 (Drosophila) 7.19378
CHN2 chimerin 2 7.19378
EGR1 early growth response 1 7.1882
PJVK pejvakin 7.15942
KLK1 kallikrein 1 7.15172
UBC ubiquitin C 7.13455
CTNNA3 catenin (cadherin-associated protein), alpha 3 7.13416
FOS FBJ murine osteosarcoma viral oncogene homolog 7.1333
CNIH3 cornichon family AMPA receptor auxiliary protein 3 7.12437
DRD4 dopamine receptor D4 7.1047
CLK1 CDC-like kinase 1 7.1009
QTRT1 queuine tRNA-ribosyltransferase 1 7.1009
FAM156A family with sequence similarity 156, member A 7.09776
ODAD2 outer dynein arm docking complex subunit 2 7.08986
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 7.08056
CSAD cysteine sulfinic acid decarboxylase 7.07494
STX16 syntaxin 16 7.07494
MANEAL mannosidase, endo-alpha-like 7.05104
EPHA5 EPH receptor A5 7.04118
STC2 stanniocalcin 2 7.03149
MEF2C-AS1 MEF2C antisense RNA 1 6.9966
FGF14 fibroblast growth factor 14 6.97228
RAB8B RAB8B, member RAS oncogene family 6.97128
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 6.9712
CTBP1 C-terminal binding protein 1 6.96149
ZFR2 zinc finger RNA binding protein 2 6.94984
JUND jun D proto-oncogene 6.92411
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 6.89913
SPTBN4 spectrin, beta, non-erythrocytic 4 6.88738
MIR3677HG MIR3677 and MIR940 host gene 6.86682
TSKU-AS1 TSKU antisense RNA 1 6.86484
HYMAI hydatidiform mole associated and imprinted (non-protein coding) 6.84891
DNAH17 dynein, axonemal, heavy chain 17 6.84812
KLHDC1 kelch domain containing 1 6.84146
TEX9 testis expressed 9 6.84029
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 6.81272
RBM19 RNA binding motif protein 19 6.7908
PYHIN1 pyrin and HIN domain family, member 1 6.77578
HESX1 HESX homeobox 1 6.77578
POGZ pogo transposable element with ZNF domain 6.76801
GBP1 guanylate binding protein 1, interferon-inducible 6.76103
DUSP2 dual specificity phosphatase 2 6.76103
DUSP8 dual specificity phosphatase 8 6.76103
CPEB1 cytoplasmic polyadenylation element binding protein 1 6.75983
LOC100422526 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) pseudogene 6.7505
NRXN1 neurexin 1 6.7449
BTG2 BTG family, member 2 6.7449
MORC3 MORC family CW-type zinc finger 3 6.7449
ULK4 unc-51 like kinase 4 6.72854
ZC2HC1A zinc finger, C2HC-type containing 1A 6.72118
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 6.71315
LINC-PINT long intergenic non-protein coding RNA, p53 induced transcript 6.70415
ACBD4 acyl-CoA binding domain containing 4 6.70415
PLA2G4B phospholipase A2, group IVB (cytosolic) 6.70415
LINC00571 long intergenic non-protein coding RNA 571 6.68372
FAS Fas cell surface death receptor 6.64662
FAM27E3 family with sequence similarity 27, member E3 6.64662
SCML2 sex comb on midleg-like 2 (Drosophila) 6.63646
CSNK1E casein kinase 1, epsilon 6.6323
COL17A1 collagen, type XVII, alpha 1 6.6323
GULP1 GULP, engulfment adaptor PTB domain containing 1 6.62775
GEM GTP binding protein overexpressed in skeletal muscle 6.62775
BORCS8-MEF2B BORCS8-MEF2B readthrough 6.61622
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 6.59932
CPNE7 copine VII 6.5966
LIPI lipase, member I 6.59092
ADM adrenomedullin 6.58945
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 6.58028
BHLHE40-AS1 BHLHE40 antisense RNA 1 6.55726
CCDC171 coiled-coil domain containing 171 6.55326
NUTM2B-AS1 NUTM2B antisense RNA 1 6.5358
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 6.5358
ZBED11 zinc finger BED-type containing 11 6.53305
RPL4P6 ribosomal protein L4 pseudogene 6 6.52762
CEP128 centrosomal protein 128kDa 6.50753
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 6.48971
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 6.47362
SPEF2 sperm flagellar 2 6.43887
ARMC2 armadillo repeat containing 2 6.41399
COX10-DT COX10 divergent transcript 6.40099
LCAT lecithin-cholesterol acyltransferase 6.40099
ZDHHC21 zinc finger, DHHC-type containing 21 6.40099
PLCD4 phospholipase C, delta 4 6.39638
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 6.37462
DCT dopachrome tautomerase 6.36715
LCDR lysosome cell death regulator 6.36572
CEROX1 cytoplasmic endogenous regulator of oxidative phosphorylation 1 6.36555
INVS inversin 6.36331
CCN2 cellular communication network factor 2 6.33874
DPH7 diphthamide biosynthesis 7 6.33671
SMKR1 small lysine-rich protein 1 6.33671
TMEM130 transmembrane protein 130 6.33376
SFRP4 secreted frizzled-related protein 4 6.33376
AZIN2 antizyme inhibitor 2 6.32936
MFAP5 microfibrillar associated protein 5 6.3229
LIME1 Lck interacting transmembrane adaptor 1 6.32105
PNISR PNN-interacting serine/arginine-rich protein 6.31074
ACYP1 acylphosphatase 1, erythrocyte (common) type 6.30562
NSUN6 NOP2/Sun domain family, member 6 6.30012
GRAMD2A GRAM domain containing 2A 6.29699
LOC100130691 uncharacterized LOC100130691 6.29569
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 6.29569
DICER1-AS1 DICER1 antisense RNA 1 6.28978
DEPDC1B DEP domain containing 1B 6.28751
GATD1-DT GATD1 divergent transcript 6.28751
TMEM123-DT TMEM123 divergent transcript 6.28593
GRIP2 glutamate receptor interacting protein 2 6.27306
PRRT2 proline-rich transmembrane protein 2 6.26762
RGS11 regulator of G-protein signaling 11 6.26762
FYB2 FYN binding protein 2 6.22339
POC1B POC1 centriolar protein B 6.21781
IRF2BP2 interferon regulatory factor 2 binding protein 2 6.20712
H2BC9 H2B clustered histone 9 6.19246
EPHA7 EPH receptor A7 6.19176
PCSK4 proprotein convertase subtilisin/kexin type 4 6.16421
ADAM33 ADAM metallopeptidase domain 33 6.15511
TRIM55 tripartite motif containing 55 6.15339
ECHDC2 enoyl CoA hydratase domain containing 2 6.13331
ANKMY1 ankyrin repeat and MYND domain containing 1 6.12647
AGBL2 ATP/GTP binding protein-like 2 6.12423
SLC6A12-AS1 SLC6A12 antisense RNA 1 6.12354
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 6.12354
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 6.12231
PAPPA2 pappalysin 2 6.10148
PCNX2 pecanex 2 6.09749
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 6.09461
PCDH9 protocadherin 9 6.09447

decreased expression

Symbol Name Standardized Value
ZNF518B zinc finger protein 518B -21.2064
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -14.7325
GIMAP6 GTPase, IMAP family member 6 -14.0881
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -14.0881
BCL9 B-cell CLL/lymphoma 9 -13.9813
CBX6 chromobox homolog 6 -13.9813
CLP1 cleavage and polyadenylation factor I subunit 1 -13.8483
HPS6 Hermansky-Pudlak syndrome 6 -13.757
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) -13.7502
INTS14 integrator complex subunit 14 -13.7113
TRIM32 tripartite motif containing 32 -13.0023
FAF2 Fas associated factor family member 2 -12.979
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -12.9743
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -12.4016
PHETA2 PH domain containing endocytic trafficking adaptor 2 -12.3021
RRAGA Ras-related GTP binding A -11.3943
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -11.2276
RFLNB refilin B -11.1806
UBASH3B ubiquitin associated and SH3 domain containing B -11.1806
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -10.9933
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -10.9746
GIMAP7 GTPase, IMAP family member 7 -10.9512
FAM43A family with sequence similarity 43, member A -10.8278
CARD6 caspase recruitment domain family, member 6 -10.8113
GPR182 G protein-coupled receptor 182 -10.7619
NCOA4 nuclear receptor coactivator 4 -10.7192
EPHB4 EPH receptor B4 -10.5736
KIFBP kinesin family binding protein -10.4416
PLRG1 pleiotropic regulator 1 -10.3937
NOL11 nucleolar protein 11 -10.3585
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -10.2772
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -10.2686
BLMH bleomycin hydrolase -10.2202
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 -10.2043
TFIP11 tuftelin interacting protein 11 -10.1971
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -10.1971
TRIM24 tripartite motif containing 24 -10.1971
LCMT2 leucine carboxyl methyltransferase 2 -10.1971
CASKIN2 CASK interacting protein 2 -10.1971
VIRMA vir like m6A methyltransferase associated -10.1524
EPHB2 EPH receptor B2 -10.1437
TSPYL5 TSPY-like 5 -10.143
ZNF792 zinc finger protein 792 -10.1405
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -10.1405
SP6 Sp6 transcription factor -9.97592
RIOK2 RIO kinase 2 -9.97592
KEAP1 kelch-like ECH-associated protein 1 -9.93005
FASTKD5 FAST kinase domains 5 -9.76182
ZBTB39 zinc finger and BTB domain containing 39 -9.74845
COA7 cytochrome c oxidase assembly factor 7 (putative) -9.74439
USP10 ubiquitin specific peptidase 10 -9.74439
INKA2 inka box actin regulator 2 -9.74439
MRPL46 mitochondrial ribosomal protein L46 -9.7053
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -9.61981
MAD2L1BP MAD2L1 binding protein -9.61981
PEX11B peroxisomal biogenesis factor 11 beta -9.61981
TOE1 target of EGR1, member 1 (nuclear) -9.54833
RPUSD2 RNA pseudouridylate synthase domain containing 2 -9.50813
MED18 mediator complex subunit 18 -9.43211
ELOVL1 ELOVL fatty acid elongase 1 -9.42883
PWP1 PWP1 homolog (S. cerevisiae) -9.38025
UMPS uridine monophosphate synthetase -9.38025
MAP10 microtubule-associated protein 10 -9.35065
TUBA1C tubulin, alpha 1c -9.35065
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -9.34465
TMEM164 transmembrane protein 164 -9.32099
TUBB4B tubulin, beta 4B class IVb -9.30157
EHD4 EH-domain containing 4 -9.29724
PSEN1 presenilin 1 -9.29724
RBM15B RNA binding motif protein 15B -9.29724
DBR1 debranching RNA lariats 1 -9.29724
SNAI2 snail family zinc finger 2 -9.29724
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -9.29724
ADPRH ADP-ribosylarginine hydrolase -9.29724
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -9.29724
RETREG3 reticulophagy regulator family member 3 -9.29196
CHPF2 chondroitin polymerizing factor 2 -9.29176
DOLK dolichol kinase -9.2635
NT5DC2 5'-nucleotidase domain containing 2 -9.20484
AHCYL1 adenosylhomocysteinase-like 1 -9.18488
COIL coilin -9.16573
ELP3 elongator acetyltransferase complex subunit 3 -9.15363
SRXN1 sulfiredoxin 1 -9.10712
FEN1 flap structure-specific endonuclease 1 -8.96861
ZNF426 zinc finger protein 426 -8.96861
GPAT4 glycerol-3-phosphate acyltransferase 4 -8.95258
CCNJ cyclin J -8.95258
SRPX sushi-repeat containing protein, X-linked -8.95258
PRDX1 peroxiredoxin 1 -8.9204
ASB8 ankyrin repeat and SOCS box containing 8 -8.91121
RIC8A RIC8 guanine nucleotide exchange factor A -8.89691
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -8.89691
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -8.84619
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -8.8241
TRIM21 tripartite motif containing 21 -8.78336
SNIP1 Smad nuclear interacting protein 1 -8.77954
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -8.75596
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -8.75278
GCLC glutamate-cysteine ligase, catalytic subunit -8.74709
FAM110D family with sequence similarity 110, member D -8.7313
TP53RK TP53 regulating kinase -8.71245
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 -8.69947
ABRAXAS2 abraxas 2, BRISC complex subunit -8.69935
MUL1 mitochondrial E3 ubiquitin protein ligase 1 -8.68782
GJA4 gap junction protein, alpha 4, 37kDa -8.65833
MIR22HG MIR22 host gene -8.65833
ABT1 activator of basal transcription 1 -8.64951
SMG8 SMG8 nonsense mediated mRNA decay factor -8.6204
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -8.59029
RARS1 arginyl-tRNA synthetase 1 -8.52585
GIMAP4 GTPase, IMAP family member 4 -8.4727
TRMT5 tRNA methyltransferase 5 -8.472
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -8.47098
BUD13 BUD13 homolog (S. cerevisiae) -8.46596
THUMPD3 THUMP domain containing 3 -8.42268
KDM1A lysine (K)-specific demethylase 1A -8.33941
NOL9 nucleolar protein 9 -8.32425
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -8.3216
TXNRD1 thioredoxin reductase 1 -8.3216
TRIM13 tripartite motif containing 13 -8.31956
MOCS3 molybdenum cofactor synthesis 3 -8.31575
ACVRL1 activin A receptor type II-like 1 -8.24062
GSPT2 G1 to S phase transition 2 -8.23641
GSK3B glycogen synthase kinase 3 beta -8.22365
ADRA1B adrenoceptor alpha 1B -8.22365
PIGBOS1 PIGB opposite strand 1 -8.19964
CDC42 cell division cycle 42 -8.18344
GSR glutathione reductase -8.16943
EDC3 enhancer of mRNA decapping 3 -8.16381
TMEM87A transmembrane protein 87A -8.16381
TBK1 TANK-binding kinase 1 -8.16381
VCP valosin containing protein -8.16176
KIRREL1 kirre like nephrin family adhesion molecule 1 -8.16176
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -8.14609
PALS2 protein associated with LIN7 2, MAGUK p55 family member -8.14071
NECTIN1 nectin cell adhesion molecule 1 -8.14071
ZNF629 zinc finger protein 629 -8.13969
TBXA2R thromboxane A2 receptor -8.13799
IP6K1 inositol hexakisphosphate kinase 1 -8.11522
SSTR2 somatostatin receptor 2 -8.11522
SPRTN SprT-like N-terminal domain -8.09411
GIMAP8 GTPase, IMAP family member 8 -8.08214
TMEM86A transmembrane protein 86A -8.0634
GPN2 GPN-loop GTPase 2 -8.00588
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -7.96509
PLAA phospholipase A2-activating protein -7.94691
TJP1 tight junction protein 1 -7.94691
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -7.94691
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -7.91196
C6ORF47 chromosome 6 open reading frame 47 -7.91196
CYFIP1 cytoplasmic FMR1 interacting protein 1 -7.90173
PROB1 proline-rich basic protein 1 -7.88301
UTP25 UTP25 small subunit processome component -7.88301
OLFM2 olfactomedin 2 -7.88301
UBIAD1 UbiA prenyltransferase domain containing 1 -7.86119
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -7.86082
C5AR2 complement component 5a receptor 2 -7.83835
DCAF7 DDB1 and CUL4 associated factor 7 -7.8351
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -7.83204
MGA MGA, MAX dimerization protein -7.83204
RAB11A RAB11A, member RAS oncogene family -7.83204
NANP N-acetylneuraminic acid phosphatase -7.81137
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -7.81137
ELOA elongin A -7.81137
CUL3 cullin 3 -7.77071
SH2D3C SH2 domain containing 3C -7.7276
MICALL1 MICAL-like 1 -7.72609
RIOX1 ribosomal oxygenase 1 -7.71873
MTCO1P12 MT-CO1 pseudogene 12 -7.7178
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -7.71204
SMC3 structural maintenance of chromosomes 3 -7.69463
CIAPIN1 cytokine induced apoptosis inhibitor 1 -7.67009
RTL6 retrotransposon Gag like 6 -7.66319
TIMP4 TIMP metallopeptidase inhibitor 4 -7.659
GPRC5B G protein-coupled receptor, class C, group 5, member B -7.64638
DCTN5 dynactin 5 (p25) -7.6458
TOMM70 translocase of outer mitochondrial membrane 70 -7.6458
BAK1 BCL2-antagonist/killer 1 -7.6458
NUP133 nucleoporin 133kDa -7.63355
MRM3 mitochondrial rRNA methyltransferase 3 -7.63076
LENG9 leukocyte receptor cluster (LRC) member 9 -7.63076
MFSD5 major facilitator superfamily domain containing 5 -7.62886
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -7.62485
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 -7.60507
SZRD1 SUZ RNA binding domain containing 1 -7.60507
CBR1 carbonyl reductase 1 -7.60074
ZBED1 zinc finger, BED-type containing 1 -7.59915
CUTC cutC copper transporter -7.57016
PDE12 phosphodiesterase 12 -7.57016
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 -7.56959
TKT transketolase -7.56693
ADCY3 adenylate cyclase 3 -7.54
CCDC71 coiled-coil domain containing 71 -7.53427
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 -7.50837
NCMAP noncompact myelin associated protein -7.49662
MTPAP mitochondrial poly(A) polymerase -7.48187
RNF24 ring finger protein 24 -7.48187
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -7.47797
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -7.47396
TRIP12 thyroid hormone receptor interactor 12 -7.46087
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -7.4545
NPAT nuclear protein, ataxia-telangiectasia locus -7.45282
GATA2 GATA binding protein 2 -7.43921
TFRC transferrin receptor -7.43296
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -7.43296
ZNF697 zinc finger protein 697 -7.4294
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -7.41484
EFTUD2 elongation factor Tu GTP binding domain containing 2 -7.41322
ZDHHC5 zinc finger, DHHC-type containing 5 -7.41186
PI15 peptidase inhibitor 15 -7.41186
RAMAC RNA guanine-7 methyltransferase activating subunit -7.41186
E2F6 E2F transcription factor 6 -7.37735
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -7.36499
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) -7.36457
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -7.35002
PBDC1 polysaccharide biosynthesis domain containing 1 -7.34405
AKR1C1 aldo-keto reductase family 1, member C1 -7.33548
EID2 EP300 interacting inhibitor of differentiation 2 -7.3351
GIMAP1 GTPase, IMAP family member 1 -7.30002
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 -7.30002
SF3B4 splicing factor 3b, subunit 4, 49kDa -7.28922
WBP1L WW domain binding protein 1-like -7.27961
FBXL5 F-box and leucine-rich repeat protein 5 -7.27961
LRRC4 leucine rich repeat containing 4 -7.27961
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -7.26905
TRIM16 tripartite motif containing 16 -7.26474
ATMIN ATM interactor -7.26474
SCAMP2 secretory carrier membrane protein 2 -7.25271
OSGIN1 oxidative stress induced growth inhibitor 1 -7.25271
INKA1 inka box actin regulator 1 -7.25271
PPP1R8 protein phosphatase 1, regulatory subunit 8 -7.22098
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -7.19398
RGS3 regulator of G-protein signaling 3 -7.19378
ZNF281 zinc finger protein 281 -7.13842
DLD dihydrolipoamide dehydrogenase -7.13514
ZSCAN12 zinc finger and SCAN domain containing 12 -7.1156
ZNF747 zinc finger protein 747 -7.10456
FECH ferrochelatase -7.10398
MRFAP1L1 Morf4 family associated protein 1-like 1 -7.10398
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -7.10398
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -7.07032
TALDO1 transaldolase 1 -7.05126
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -7.03553
ZNF587B zinc finger protein 587B -7.03293
TUBB tubulin, beta class I -7.03293
ELAC2 elaC ribonuclease Z 2 -7.02767
KCTD21 potassium channel tetramerization domain containing 21 -7.02767
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -6.98905
GJC1 gap junction protein, gamma 1, 45kDa -6.97825
ZBTB24 zinc finger and BTB domain containing 24 -6.97128