GUCY1A2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description guanylate cyclase 1, soluble, alpha 2|Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 2977)
External Link https://ncbi.nlm.nih.gov/gene/2977
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Genes

500 genes differentially expressed following the GUCY1A2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0184539
TM4SF1 transmembrane 4 L six family member 1 0.0172326
PEG10 paternally expressed 10 0.0154936
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0152586
RGCC regulator of cell cycle 0.01363
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0131396
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0124694
FABP4 fatty acid binding protein 4, adipocyte 0.0111392
FOLR1 folate receptor 1 (adult) 0.0109699
LAPTM4B lysosomal protein transmembrane 4 beta 0.0109002
KLK5 kallikrein-related peptidase 5 0.010833
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0107888
CADM1 cell adhesion molecule 1 0.0104232
ATF3 activating transcription factor 3 0.0103363
CLEC2B C-type lectin domain family 2, member B 0.00985741
CAV1 caveolin 1, caveolae protein, 22kDa 0.00983709
CFB complement factor B 0.00976498
SLPI secretory leukocyte peptidase inhibitor 0.00952596
GNAS GNAS complex locus 0.00943136
PPL periplakin 0.00922666
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00901735
HSPB1 heat shock 27kDa protein 1 0.0089085
BTG3 BTG family, member 3 0.00888853
FGG fibrinogen gamma chain 0.00870982
HSPA1A heat shock 70kDa protein 1A 0.00862853
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00861752
KRT17 keratin 17, type I 0.00860688
CP ceruloplasmin (ferroxidase) 0.00853365
NIBAN1 niban apoptosis regulator 1 0.00843837
MYO1B myosin IB 0.0082611
FZD6 frizzled class receptor 6 0.00822944
TACSTD2 tumor-associated calcium signal transducer 2 0.00818515
AK4 adenylate kinase 4 0.00814537
BEX4 brain expressed, X-linked 4 0.00807115
CD59 CD59 molecule, complement regulatory protein 0.00797202
ANXA3 annexin A3 0.00794836
AQP3 aquaporin 3 (Gill blood group) 0.00793262
ACSL4 acyl-CoA synthetase long-chain family member 4 0.00791732
FN1 fibronectin 1 0.00788635
INHBB inhibin, beta B 0.00787394
JUNB jun B proto-oncogene 0.0077866
KRT5 keratin 5, type II 0.00773204
CXADR coxsackie virus and adenovirus receptor 0.0076123
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00756686
PLK2 polo-like kinase 2 0.00755181
NSG1 neuron specific gene family member 1 0.00749447
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00746553
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00742662
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.00741541
GIMAP6 GTPase, IMAP family member 6 0.00741066
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00735386
KLK8 kallikrein-related peptidase 8 0.00732743
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00731274
RPN2 ribophorin II 0.0072681
ABLIM1 actin binding LIM protein 1 0.00723911
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00722378
TSC22D1 TSC22 domain family, member 1 0.0071058
IFITM3 interferon induced transmembrane protein 3 0.00709962
KAZN kazrin, periplakin interacting protein 0.00708528
ANXA1 annexin A1 0.00704929
LAMP3 lysosomal-associated membrane protein 3 0.00694212
CRABP2 cellular retinoic acid binding protein 2 0.00687875
DMAC2L distal membrane arm assembly component 2 like 0.00686472
C8ORF4 chromosome 8 open reading frame 4 0.00685675
MYO1C myosin IC 0.00684105
IFI44L interferon-induced protein 44-like 0.00681788
C3 complement component 3 0.00677014
NRN1 neuritin 1 0.00670689
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00670388
CAV2 caveolin 2 0.00669374
CXCL10 chemokine (C-X-C motif) ligand 10 0.00668763
PLP1 proteolipid protein 1 0.00665272
TPD52 tumor protein D52 0.00662646
SST somatostatin 0.00655108
S100A2 S100 calcium binding protein A2 0.00653156
ADIPOQ adiponectin, C1Q and collagen domain containing 0.0065147
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00651261
AFP alpha-fetoprotein 0.00649794
LYPLA1 lysophospholipase I 0.00647484
EMP1 epithelial membrane protein 1 0.00646426
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00645499
DOCK9 dedicator of cytokinesis 9 0.00641695
CYB5A cytochrome b5 type A (microsomal) 0.00639287
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00637399
IL1A interleukin 1, alpha 0.00636881
CD69 CD69 molecule 0.00631168
S100A7 S100 calcium binding protein A7 0.00630132
NPY neuropeptide Y 0.00629057
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00627954
TAC1 tachykinin, precursor 1 0.00625467
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00622568
LYRM2 LYR motif containing 2 0.00620221
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00619033
IL1RN interleukin 1 receptor antagonist 0.00618129
DCLK1 doublecortin-like kinase 1 0.00613308
CD34 CD34 molecule 0.00611267
APOB apolipoprotein B 0.0060906
EIF5A eukaryotic translation initiation factor 5A 0.00607916
LOX lysyl oxidase 0.00606896
KLK7 kallikrein-related peptidase 7 0.0060588
IFITM1 interferon induced transmembrane protein 1 0.00604055
ARL5A ADP-ribosylation factor-like 5A 0.00601971
ITGA6 integrin, alpha 6 0.0060139
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00601023
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00599616
OLFML2A olfactomedin-like 2A 0.00595771
ADGRF5 adhesion G protein-coupled receptor F5 0.00595156
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00594771
KANK1 KN motif and ankyrin repeat domains 1 0.00594595
SQLE squalene epoxidase 0.00592826
LIMS1 LIM and senescent cell antigen-like domains 1 0.00592665
PDLIM1 PDZ and LIM domain 1 0.00592247
GPX3 glutathione peroxidase 3 0.00591552
CLIC5 chloride intracellular channel 5 0.00589583
S100A4 S100 calcium binding protein A4 0.00585244
SCEL sciellin 0.0058497
CLCA2 chloride channel accessory 2 0.00583366
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.00582718
FASTKD1 FAST kinase domains 1 0.00582148
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00581613
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00581016
MTUS1 microtubule associated tumor suppressor 1 0.0057998
H1-2 H1.2 linker histone, cluster member 0.00579948
MPHOSPH8 M-phase phosphoprotein 8 0.00579607
GPC3 glypican 3 0.00579346
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00577797
SNAP25 synaptosomal-associated protein, 25kDa 0.00577729
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00576069
AQP1 aquaporin 1 (Colton blood group) 0.00575773
TSPAN8 tetraspanin 8 0.00573258
MYOF myoferlin 0.00572863
ALB albumin 0.00570517
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00570172
ELL2 elongation factor, RNA polymerase II, 2 0.00569797
PTK2 protein tyrosine kinase 2 0.00569195
TRIB2 tribbles pseudokinase 2 0.00568775
MDH1 malate dehydrogenase 1, NAD (soluble) 0.00567066
CAPN3 calpain 3, (p94) 0.00567059
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00560214
UBAP2 ubiquitin associated protein 2 0.0055807
SYT1 synaptotagmin I 0.00557965
NCOA4 nuclear receptor coactivator 4 0.00557183
DEFB1 defensin, beta 1 0.00555502
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00555432
FGFR1 fibroblast growth factor receptor 1 0.00555108
HK2 hexokinase 2 0.00554367
CRYBG1 crystallin beta-gamma domain containing 1 0.0055434
PON2 paraoxonase 2 0.00553663
IFT57 intraflagellar transport 57 0.00553364
TUBB2A tubulin, beta 2A class IIa 0.00551518
KLK6 kallikrein-related peptidase 6 0.00551403
MTX2 metaxin 2 0.00549566
IRS2 insulin receptor substrate 2 0.0054918
LEPROT leptin receptor overlapping transcript 0.00547166
MTIF2 mitochondrial translational initiation factor 2 0.00546638
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00545266
MALL mal, T-cell differentiation protein-like 0.00544939
GAL galanin/GMAP prepropeptide 0.00543374
LITAF lipopolysaccharide-induced TNF factor 0.00543131
HSPA8 heat shock 70kDa protein 8 0.00542226
PPA1 pyrophosphatase (inorganic) 1 0.00539736
IFI27 interferon, alpha-inducible protein 27 0.0053949
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 0.00536539
FXYD3 FXYD domain containing ion transport regulator 3 0.00536065
PEA15 phosphoprotein enriched in astrocytes 15 0.00535647
LPAR6 lysophosphatidic acid receptor 6 0.0053502
SKP1 S-phase kinase-associated protein 1 0.00534713
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00534155
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00532848
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00532712
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00532647
RALB v-ral simian leukemia viral oncogene homolog B 0.00532457
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00532026
KRT14 keratin 14, type I 0.00531772
CANX calnexin 0.00530433
PRSS23 protease, serine, 23 0.00530012
A2M alpha-2-macroglobulin 0.00529284
F3 coagulation factor III (thromboplastin, tissue factor) 0.00528897
DDIT3 DNA-damage-inducible transcript 3 0.00528759
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0052721
EGR2 early growth response 2 0.00525904
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.0052498
ATAD2 ATPase family, AAA domain containing 2 0.00524117
IFNGR1 interferon gamma receptor 1 0.00522741
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.0052204
TRAM1 translocation associated membrane protein 1 0.00521727
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00520142
PRTN3 proteinase 3 0.00520013
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00515346
HSPH1 heat shock 105kDa/110kDa protein 1 0.00514991
MARCHF7 membrane associated ring-CH-type finger 7 0.00514559
FLT1 fms-related tyrosine kinase 1 0.00513224
STK39 serine threonine kinase 39 0.00512714
CRABP1 cellular retinoic acid binding protein 1 0.00512141
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00511693
ZNF281 zinc finger protein 281 0.0051065
SGCE sarcoglycan, epsilon 0.00509771
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00509691
NCALD neurocalcin delta 0.00509036
PGC progastricsin (pepsinogen C) 0.00507708
CLEC2D C-type lectin domain family 2, member D 0.00507291
CNN3 calponin 3, acidic 0.00507005
SIRT3 sirtuin 3 0.00506677
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00506048
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00505964
PLVAP plasmalemma vesicle associated protein 0.0050555
TSPAN3 tetraspanin 3 0.00501859
CRCT1 cysteine-rich C-terminal 1 0.00499902
FRMD4B FERM domain containing 4B 0.00499767
SOS1 son of sevenless homolog 1 (Drosophila) 0.00499435
CAB39 calcium binding protein 39 0.00499052
CA6 carbonic anhydrase VI 0.00498478
RHOBTB3 Rho-related BTB domain containing 3 0.00498296
ARHGAP15 Rho GTPase activating protein 15 0.00496989
PABPC3 poly(A) binding protein, cytoplasmic 3 0.00496025
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00494973
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.00494559
AMPD3 adenosine monophosphate deaminase 3 0.00493903
VSNL1 visinin-like 1 0.00492465
ECHDC1 ethylmalonyl-CoA decarboxylase 1 0.00492147
CFI complement factor I 0.00492092
MGST2 microsomal glutathione S-transferase 2 0.00491639
ERGIC2 ERGIC and golgi 2 0.00489131
VAMP8 vesicle-associated membrane protein 8 0.00488225
ASS1 argininosuccinate synthase 1 0.00487527
CLTA clathrin, light chain A 0.00487063
SPARCL1 SPARC-like 1 (hevin) 0.00487042
PCSK6 proprotein convertase subtilisin/kexin type 6 0.00484875
CAVIN2 caveolae associated protein 2 0.00483711
TRIM14 tripartite motif containing 14 0.0048327
LYPD1 LY6/PLAUR domain containing 1 0.00483221
SAV1 salvador family WW domain containing protein 1 0.00483068
GOLT1B golgi transport 1B 0.00482698
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.004821
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00481623
DNM1L dynamin 1-like 0.00480708
BAMBI BMP and activin membrane-bound inhibitor 0.00480667
IFIH1 interferon induced with helicase C domain 1 0.00479783
FST follistatin 0.00478807
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00477817
GDE1 glycerophosphodiester phosphodiesterase 1 0.00476456
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.0047615
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00474408
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.00474025
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.00473056
ZNF750 zinc finger protein 750 0.00471586
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00470627
AUTS2 autism susceptibility candidate 2 0.00470138
OXA1L oxidase (cytochrome c) assembly 1-like 0.00469138
RAB38 RAB38, member RAS oncogene family 0.00467997

decreased expression

Symbol Name Standardized Value
XPO7 exportin 7 -0.0215776
TFF3 trefoil factor 3 (intestinal) -0.0109982
ANXA6 annexin A6 -0.0108413
OLFM4 olfactomedin 4 -0.0105808
ZBTB18 zinc finger and BTB domain containing 18 -0.0105355
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0104733
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0102739
WASHC4 WASH complex subunit 4 -0.0100538
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00997044
SFRP4 secreted frizzled-related protein 4 -0.00974969
TFF1 trefoil factor 1 -0.00921757
BLNK B-cell linker -0.00894101
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00871631
LYZ lysozyme -0.00866685
LEFTY1 left-right determination factor 1 -0.00825334
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00823347
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00818081
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00816301
PALLD palladin, cytoskeletal associated protein -0.00796911
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00788581
MMP12 matrix metallopeptidase 12 -0.00782683
PDZRN3 PDZ domain containing ring finger 3 -0.00781974
SSBP2 single-stranded DNA binding protein 2 -0.00776249
VCAN versican -0.00764029
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00760225
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.0076022
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00758845
ESR1 estrogen receptor 1 -0.00745598
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00743412
METRN meteorin, glial cell differentiation regulator -0.00742565
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00732884
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00720746
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00712048
CTSZ cathepsin Z -0.00700153
SMTN smoothelin -0.00696141
LMNB2 lamin B2 -0.00693292
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00683964
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00683091
TMEM176B transmembrane protein 176B -0.00680876
MZB1 marginal zone B and B1 cell-specific protein -0.00677335
BMP6 bone morphogenetic protein 6 -0.00677022
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.00673188
CDC20 cell division cycle 20 -0.00668138
SATB2 SATB homeobox 2 -0.00663695
BPGM 2,3-bisphosphoglycerate mutase -0.00661441
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00659677
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00658535
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00658219
VNN1 vanin 1 -0.00651388
LMNB1 lamin B1 -0.00641637
POU2AF1 POU class 2 associating factor 1 -0.00640716
LTBP2 latent transforming growth factor beta binding protein 2 -0.00640322
MACROD1 MACRO domain containing 1 -0.00639984
PTPRD protein tyrosine phosphatase, receptor type, D -0.00639792
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00639523
FLNC filamin C, gamma -0.00637913
GRB14 growth factor receptor-bound protein 14 -0.00633455
TMCC2 transmembrane and coiled-coil domain family 2 -0.00632631
FKBP10 FK506 binding protein 10, 65 kDa -0.00629257
RAPSN receptor-associated protein of the synapse -0.00627321
HOXC6 homeobox C6 -0.00624381
MCOLN1 mucolipin 1 -0.00619921
AHSP alpha hemoglobin stabilizing protein -0.00619628
PSD3 pleckstrin and Sec7 domain containing 3 -0.00610295
PRKD1 protein kinase D1 -0.00606628
CAPN6 calpain 6 -0.0060346
ADGRE5 adhesion G protein-coupled receptor E5 -0.00599605
AKAP8 A kinase (PRKA) anchor protein 8 -0.0059913
DMTN dematin actin binding protein -0.00597641
PRF1 perforin 1 (pore forming protein) -0.00594836
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00594229
GAS1 growth arrest-specific 1 -0.00589872
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00589799
TPM2 tropomyosin 2 (beta) -0.00587169
ANPEP alanyl (membrane) aminopeptidase -0.00583974
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00581173
PLN phospholamban -0.00580954
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00577962
AOC1 amine oxidase, copper containing 1 -0.00576758
ALAS2 5'-aminolevulinate synthase 2 -0.00575596
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00574236
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00574101
DES desmin -0.00572357
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00571356
CD8A CD8a molecule -0.00570204
EPHB2 EPH receptor B2 -0.00569829
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00569829
CYBB cytochrome b-245, beta polypeptide -0.00566708
PCDH9 protocadherin 9 -0.00566189
FBN2 fibrillin 2 -0.00565705
FECH ferrochelatase -0.00563099
PDGFRL platelet-derived growth factor receptor-like -0.00559522
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00554176
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00553041
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00551344
LTBP4 latent transforming growth factor beta binding protein 4 -0.00551194
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0054765
NDRG2 NDRG family member 2 -0.0054585
PLCL2 phospholipase C-like 2 -0.00544978
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00542989
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00542881
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00542716
GPSM2 G-protein signaling modulator 2 -0.00542344
REG1B regenerating islet-derived 1 beta -0.00542294
KANK2 KN motif and ankyrin repeat domains 2 -0.00541714
G0S2 G0/G1 switch 2 -0.00540764
INTS1 integrator complex subunit 1 -0.00540147
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00538271
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00534914
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog -0.00533664
RBM34 RNA binding motif protein 34 -0.00533222
XYLT1 xylosyltransferase I -0.00532654
PTPRE protein tyrosine phosphatase, receptor type, E -0.00531579
MMP9 matrix metallopeptidase 9 -0.00528497
COL6A2 collagen, type VI, alpha 2 -0.0052754
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.00527535
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00527308
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.00526128
RAB40B RAB40B, member RAS oncogene family -0.00525516
LAMB1 laminin, beta 1 -0.00525212
CCL19 chemokine (C-C motif) ligand 19 -0.00525074
TM9SF3 transmembrane 9 superfamily member 3 -0.00524513
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -0.00522196
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00521361
PDLIM3 PDZ and LIM domain 3 -0.00520847
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00520732
MRC2 mannose receptor, C type 2 -0.00517626
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -0.00517322
KRT19 keratin 19, type I -0.00515832
SDC1 syndecan 1 -0.0051442
NME3 NME/NM23 nucleoside diphosphate kinase 3 -0.00512817
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) -0.00509234
F12 coagulation factor XII (Hageman factor) -0.00509178
DPEP1 dipeptidase 1 (renal) -0.00508839
ADAM28 ADAM metallopeptidase domain 28 -0.00507613
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0050651
ITM2C integral membrane protein 2C -0.00504361
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00503676
ZDHHC17 zinc finger, DHHC-type containing 17 -0.00503367
AKAP7 A kinase (PRKA) anchor protein 7 -0.0050213
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00499915
REG1A regenerating islet-derived 1 alpha -0.00499511
TTC38 tetratricopeptide repeat domain 38 -0.00498293
NPM3 nucleophosmin/nucleoplasmin 3 -0.00498051
FLT3 fms-related tyrosine kinase 3 -0.00497981
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.0049795
CCR2 chemokine (C-C motif) receptor 2 -0.00497482
HCK HCK proto-oncogene, Src family tyrosine kinase -0.00496468
ADAM19 ADAM metallopeptidase domain 19 -0.00493221
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00493074
RNF11 ring finger protein 11 -0.00491796
RRBP1 ribosome binding protein 1 -0.00490627
CTBP2 C-terminal binding protein 2 -0.00489893
HBD hemoglobin, delta -0.00489082
ASPN asporin -0.00488897
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00488636
TRPS1 trichorhinophalangeal syndrome I -0.00487714
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00487665
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00487488
LAT2 linker for activation of T cells family, member 2 -0.00486983
GRAMD4 GRAM domain containing 4 -0.00486416
COL14A1 collagen, type XIV, alpha 1 -0.00486269
TCL1A T-cell leukemia/lymphoma 1A -0.00486001
PDE10A phosphodiesterase 10A -0.00485676
MTMR9 myotubularin related protein 9 -0.00485336
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -0.004842
CNPY3 canopy FGF signaling regulator 3 -0.00484012
C12ORF29 chromosome 12 open reading frame 29 -0.00483212
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00480285
ZNF423 zinc finger protein 423 -0.00479995
GOLIM4 golgi integral membrane protein 4 -0.00478639
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00478149
MME membrane metallo-endopeptidase -0.00477546
EMP3 epithelial membrane protein 3 -0.00476508
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.00474893
COL16A1 collagen, type XVI, alpha 1 -0.00474857
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00474335
CYBA cytochrome b-245, alpha polypeptide -0.00474042
NID2 nidogen 2 (osteonidogen) -0.00473681
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00473617
MTMR11 myotubularin related protein 11 -0.00473083
SPON2 spondin 2, extracellular matrix protein -0.0047288
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00472175
EPB42 erythrocyte membrane protein band 4.2 -0.00471237
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) -0.00470529
TMEM176A transmembrane protein 176A -0.00469286
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00469271
HIP1R huntingtin interacting protein 1 related -0.00469184
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.0046904
KIAA0226L KIAA0226-like -0.00467898
DSE dermatan sulfate epimerase -0.00467205
COL5A1 collagen, type V, alpha 1 -0.00467116
TNNT1 troponin T type 1 (skeletal, slow) -0.00465898
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00465689
ZNF274 zinc finger protein 274 -0.0046192
TTC39A tetratricopeptide repeat domain 39A -0.00461114
ATG2A autophagy related 2A -0.00460488
OSBPL8 oxysterol binding protein-like 8 -0.00459811
GATAD2A GATA zinc finger domain containing 2A -0.00459574
FAM131A family with sequence similarity 131, member A -0.00459077
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.00458975
CHMP7 charged multivesicular body protein 7 -0.00458883
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00457946
CA12 carbonic anhydrase XII -0.00456487
RAD9A RAD9 homolog A (S. pombe) -0.00455208
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.00455029
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -0.00454597
FERMT1 fermitin family member 1 -0.00454588
RAD23B RAD23 homolog B (S. cerevisiae) -0.00454487
THY1 Thy-1 cell surface antigen -0.00454441
CLIP3 CAP-GLY domain containing linker protein 3 -0.00454305
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -0.00452382
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00452061
ABHD2 abhydrolase domain containing 2 -0.00450125
ECT2 epithelial cell transforming 2 -0.00449744
FBP1 fructose-1,6-bisphosphatase 1 -0.00449408
TYROBP TYRO protein tyrosine kinase binding protein -0.00447521
EFHD2 EF-hand domain family, member D2 -0.00447299
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00446697
SRGN serglycin -0.00446468
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00445273
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00444523
HEPH hephaestin -0.00443841
RUVBL1 RuvB-like AAA ATPase 1 -0.00443768
IL7R interleukin 7 receptor -0.00442877
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00441454
CFP complement factor properdin -0.00441431
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.00440796
MPP1 membrane protein, palmitoylated 1, 55kDa -0.00440766
WISP1 WNT1 inducible signaling pathway protein 1 -0.00439795
LMCD1 LIM and cysteine-rich domains 1 -0.0043926
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00439189
HSPA13 heat shock protein 70kDa family, member 13 -0.00439133
CCR1 chemokine (C-C motif) receptor 1 -0.00434345
SELENBP1 selenium binding protein 1 -0.00434274
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.0043218
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.00431678
CD2 CD2 molecule -0.00431416
CTIF CBP80/20-dependent translation initiation factor -0.00431088
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00430519
ARHGAP33 Rho GTPase activating protein 33 -0.00430067
SLC38A1 solute carrier family 38, member 1 -0.00429796
PROCR protein C receptor, endothelial -0.00428971
ENGASE endo-beta-N-acetylglucosaminidase -0.00428608
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00428264
MED13L mediator complex subunit 13-like -0.00427253
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00425582
TOP2A topoisomerase (DNA) II alpha 170kDa -0.00425422
MFAP3L microfibrillar-associated protein 3-like -0.00425257
IL2RB interleukin 2 receptor, beta -0.00424388