GUCY1A2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description guanylate cyclase 1, soluble, alpha 2|Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 2977)
External Link http://www.ncbi.nlm.nih.gov/gene/2977
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32 interacting proteins for GUCY1A2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
CADM1 cell adhesion molecule 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
DLG1 discs, large homolog 1 (Drosophila)
DLG2 discs, large homolog 2 (Drosophila)
DLG3 discs, large homolog 3 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERBB2IP erbb2 interacting protein
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
INADL InaD-like (Drosophila)
LIN7A lin-7 homolog A (C. elegans)
MPDZ multiple PDZ domain protein
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PRKG1 protein kinase, cGMP-dependent, type I
PRKG2 protein kinase, cGMP-dependent, type II
PXDC1 PX domain containing 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SNTA1 syntrophin, alpha 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
UBC ubiquitin C