GUCY1B3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description guanylate cyclase 1, soluble, beta 3|This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 2983)
External Link http://www.ncbi.nlm.nih.gov/gene/2983
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Genes

29 interacting proteins for GUCY1B3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
APP amyloid beta (A4) precursor protein
CADM1 cell adhesion molecule 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
DLG1 discs, large homolog 1 (Drosophila)
EPB41L2 erythrocyte membrane protein band 4.1-like 2
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
INADL InaD-like (Drosophila)
LIN7A lin-7 homolog A (C. elegans)
MPDZ multiple PDZ domain protein
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PRKG1 protein kinase, cGMP-dependent, type I
PRKG2 protein kinase, cGMP-dependent, type II
PXDC1 PX domain containing 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
UBC ubiquitin C