GW-5074 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
Similar Terms
Downloads & Tools

Genes

33 kinases inhibited by the GW-5074 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.32726
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.3104
GAK cyclin G associated kinase 1.23916
DAPK2 death-associated protein kinase 2 1.21703
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1.20983
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 1.20271
MYO3A myosin IIIA 1.17508
STK17A serine/threonine kinase 17a 1.17508
DAPK3 death-associated protein kinase 3 1.16838
TNIK TRAF2 and NCK interacting kinase 1.16177
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.15523
HUNK hormonally up-regulated Neu-associated kinase 1.15523
MINK1 misshapen-like kinase 1 1.15523
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.12988
STK3 serine/threonine kinase 3 1.12373
FLT3 fms-related tyrosine kinase 3 1.10576
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.0718
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.0718
MAPK7 mitogen-activated protein kinase 7 1.03041
AAK1 AP2 associated kinase 1 1.02071
CIT citron rho-interacting serine/threonine kinase 1.00208
DAPK1 death-associated protein kinase 1 0.975893
HIPK2 homeodomain interacting protein kinase 2 0.922275
SRPK3 SRSF protein kinase 3 0.915387
HIPK3 homeodomain interacting protein kinase 3 0.908676
MYO3B myosin IIIB 0.889549
BMPR1B bone morphogenetic protein receptor, type IB 0.883492
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.877587
AURKB aurora kinase B 0.866209
BMP2K BMP2 inducible kinase 0.858037
TGFBR1 transforming growth factor, beta receptor 1 0.850157
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.850157
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.850157