| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the GW-8510-7062 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATP11A | ATPase, class VI, type 11A |
| B9D1 | B9 protein domain 1 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| CA4 | carbonic anhydrase IV |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCDC88C | coiled-coil domain containing 88C |
| CD320 | CD320 molecule |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL5A1 | collagen, type V, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CST6 | cystatin E/M |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FSCN1 | fascin actin-bundling protein 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLB1L | galactosidase, beta 1-like |
| GM2A | GM2 ganglioside activator |
| GPC1 | glypican 1 |
| GPX1 | glutathione peroxidase 1 |
| HBS1L | HBS1-like translational GTPase |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HIST1H2AM | histone cluster 1, H2am |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IER3 | immediate early response 3 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KIAA0368 | KIAA0368 |
| KIF1A | kinesin family member 1A |
| KLF6 | Kruppel-like factor 6 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LYRM9 | LYR motif containing 9 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MCFD2 | multiple coagulation factor deficiency 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMP25 | matrix metallopeptidase 25 |
| MSMB | microseminoprotein, beta- |
| MT1E | metallothionein 1E |
| NF1 | neurofibromin 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
| OLFML3 | olfactomedin-like 3 |
| PARVA | parvin, alpha |
| PDLIM5 | PDZ and LIM domain 5 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PODNL1 | podocan-like 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
| RPL23 | ribosomal protein L23 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS28 | ribosomal protein S28 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100A11 | S100 calcium binding protein A11 |
| S100A6 | S100 calcium binding protein A6 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SRPX | sushi-repeat containing protein, X-linked |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SYMPK | symplekin |
| TCF3 | transcription factor 3 |
| TFF3 | trefoil factor 3 (intestinal) |
| TH | tyrosine hydroxylase |
| TLN2 | talin 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPSG1 | tryptase gamma 1 |
| TUBA3D | tubulin, alpha 3d |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFB | vascular endothelial growth factor B |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WWOX | WW domain containing oxidoreductase |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ADNP | activity-dependent neuroprotector homeobox |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD49 | ankyrin repeat domain 49 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C11ORF57 | chromosome 11 open reading frame 57 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C7ORF49 | chromosome 7 open reading frame 49 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CDCA4 | cell division cycle associated 4 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CENPE | centromere protein E, 312kDa |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLK1 | CDC-like kinase 1 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| DCLRE1B | DNA cross-link repair 1B |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DOLK | dolichol kinase |
| E2F6 | E2F transcription factor 6 |
| EFNA1 | ephrin-A1 |
| EFNA4 | ephrin-A4 |
| EGR3 | early growth response 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FANCF | Fanconi anemia, complementation group F |
| FBXO5 | F-box protein 5 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FOXD1 | forkhead box D1 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GPATCH1 | G patch domain containing 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HJURP | Holliday junction recognition protein |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| ING3 | inhibitor of growth family, member 3 |
| IRS1 | insulin receptor substrate 1 |
| IRX5 | iroquois homeobox 5 |
| JMJD1C | jumonji domain containing 1C |
| KIAA0922 | KIAA0922 |
| KIAA1551 | KIAA1551 |
| KIF16B | kinesin family member 16B |
| KIF20B | kinesin family member 20B |
| KRCC1 | lysine-rich coiled-coil 1 |
| LEMD3 | LEM domain containing 3 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| METTL18 | methyltransferase like 18 |
| MGA | MGA, MAX dimerization protein |
| MKL2 | MKL/myocardin-like 2 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NDC80 | NDC80 kinetochore complex component |
| NPY1R | neuropeptide Y receptor Y1 |
| PALB2 | partner and localizer of BRCA2 |
| PLK2 | polo-like kinase 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 |
| PRR15L | proline rich 15-like |
| RANBP6 | RAN binding protein 6 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RNMTL1 | RNA methyltransferase like 1 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| SLC38A2 | solute carrier family 38, member 2 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TBCC | tubulin folding cofactor C |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRIB1 | tribbles pseudokinase 1 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPYL5 | TSPY-like 5 |
| VANGL1 | VANGL planar cell polarity protein 1 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZIC1 | Zic family member 1 |
| ZNF107 | zinc finger protein 107 |
| ZNF146 | zinc finger protein 146 |
| ZNF217 | zinc finger protein 217 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF443 | zinc finger protein 443 |