| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the GW-8510-7067 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APP | amyloid beta (A4) precursor protein |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| B9D1 | B9 protein domain 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CCNT2 | cyclin T2 |
| CD24 | CD24 molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLDN1 | claudin 1 |
| CTSZ | cathepsin Z |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DUSP1 | dual specificity phosphatase 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ERCC1 | excision repair cross-complementation group 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FCMR | Fc fragment of IgM receptor |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FH | fumarate hydratase |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GTPBP4 | GTP binding protein 4 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BG | histone cluster 1, H2bg |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXB2 | homeobox B2 |
| IL6 | interleukin 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KIAA0368 | KIAA0368 |
| KLF2 | Kruppel-like factor 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT4 | keratin 4, type II |
| LIMK1 | LIM domain kinase 1 |
| LOC157562 | uncharacterized LOC157562 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| MAOA | monoamine oxidase A |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MED6 | mediator complex subunit 6 |
| METTL5 | methyltransferase like 5 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NCS1 | neuronal calcium sensor 1 |
| NGDN | neuroguidin, EIF4E binding protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARVB | parvin, beta |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLXNA3 | plexin A3 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| QKI | QKI, KH domain containing, RNA binding |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RHOB | ras homolog family member B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL14 | ribosomal protein L14 |
| RPS9 | ribosomal protein S9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SIK1 | salt-inducible kinase 1 |
| SLC22A13 | solute carrier family 22 (organic anion/urate transporter), member 13 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAGLN3 | transgelin 3 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TGFB2 | transforming growth factor, beta 2 |
| TH | tyrosine hydroxylase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPM2 | tropomyosin 2 (beta) |
| TTC12 | tetratricopeptide repeat domain 12 |
| URI1 | URI1, prefoldin-like chaperone |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| Symbol | Name |
|---|---|
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| ANKRD49 | ankyrin repeat domain 49 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARL4A | ADP-ribosylation factor-like 4A |
| BAG3 | BCL2-associated athanogene 3 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBR3 | carbonyl reductase 3 |
| CDCA4 | cell division cycle associated 4 |
| CDCA8 | cell division cycle associated 8 |
| CDKN2AIP | CDKN2A interacting protein |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CLK4 | CDC-like kinase 4 |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTCF | CCCTC-binding factor (zinc finger protein) |
| DBF4 | DBF4 zinc finger |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
| DUSP6 | dual specificity phosphatase 6 |
| E2F6 | E2F transcription factor 6 |
| E2F8 | E2F transcription factor 8 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FBXO34 | F-box protein 34 |
| FBXO5 | F-box protein 5 |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| FOXD1 | forkhead box D1 |
| FZD8 | frizzled class receptor 8 |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) |
| GPR87 | G protein-coupled receptor 87 |
| GSPT2 | G1 to S phase transition 2 |
| GTF2B | general transcription factor IIB |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAS2 | hyaluronan synthase 2 |
| HAUS3 | HAUS augmin-like complex, subunit 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HJURP | Holliday junction recognition protein |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IRS1 | insulin receptor substrate 1 |
| JMJD1C | jumonji domain containing 1C |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIF23 | kinesin family member 23 |
| KLHL21 | kelch-like family member 21 |
| LEMD3 | LEM domain containing 3 |
| LIPT1 | lipoyltransferase 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MED7 | mediator complex subunit 7 |
| MFSD5 | major facilitator superfamily domain containing 5 |
| MGA | MGA, MAX dimerization protein |
| NDC80 | NDC80 kinetochore complex component |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NRBF2 | nuclear receptor binding factor 2 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PEX11B | peroxisomal biogenesis factor 11 beta |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| RANBP6 | RAN binding protein 6 |
| RBM7 | RNA binding motif protein 7 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNF111 | ring finger protein 111 |
| RNF113A | ring finger protein 113A |
| RNMTL1 | RNA methyltransferase like 1 |
| RSBN1 | round spermatid basic protein 1 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SIRT1 | sirtuin 1 |
| SIRT7 | sirtuin 7 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SUV420H1 | suppressor of variegation 4-20 homolog 1 (Drosophila) |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TBCC | tubulin folding cofactor C |
| TEFM | transcription elongation factor, mitochondrial |
| THAP11 | THAP domain containing 11 |
| TOB1 | transducer of ERBB2, 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM13 | tripartite motif containing 13 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSPYL5 | TSPY-like 5 |
| TTK | TTK protein kinase |
| XBP1 | X-box binding protein 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF217 | zinc finger protein 217 |
| ZNF248 | zinc finger protein 248 |
| ZNF443 | zinc finger protein 443 |
| ZNF7 | zinc finger protein 7 |
