| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the GW-8510-7080 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACACA | acetyl-CoA carboxylase alpha |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AK2 | adenylate kinase 2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AMT | aminomethyltransferase |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APC | adenomatous polyposis coli |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APP | amyloid beta (A4) precursor protein |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATF6B | activating transcription factor 6 beta |
| ATXN2L | ataxin 2-like |
| BMP5 | bone morphogenetic protein 5 |
| BMP7 | bone morphogenetic protein 7 |
| CASZ1 | castor zinc finger 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD46 | CD46 molecule, complement regulatory protein |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DRD2 | dopamine receptor D2 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FECH | ferrochelatase |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| FUS | FUS RNA binding protein |
| GALC | galactosylceramidase |
| GLRX3 | glutaredoxin 3 |
| GOLIM4 | golgi integral membrane protein 4 |
| GPR137 | G protein-coupled receptor 137 |
| GPX1 | glutathione peroxidase 1 |
| GPX2 | glutathione peroxidase 2 |
| HABP4 | hyaluronan binding protein 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4D | histone cluster 1, H4d |
| HSF2 | heat shock transcription factor 2 |
| HTT | huntingtin |
| IER3 | immediate early response 3 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| IRAK1 | interleukin-1 receptor-associated kinase 1 |
| IRF5 | interferon regulatory factor 5 |
| ITGB5 | integrin, beta 5 |
| KIAA0368 | KIAA0368 |
| LAD1 | ladinin 1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LMF2 | lipase maturation factor 2 |
| LMNA | lamin A/C |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MOSPD3 | motile sperm domain containing 3 |
| MT1G | metallothionein 1G |
| MYL5 | myosin, light chain 5, regulatory |
| NADK | NAD kinase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEB | nebulin |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCBP2 | poly(rC) binding protein 2 |
| PCGF2 | polycomb group ring finger 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLA2G10 | phospholipase A2, group X |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PRAF2 | PRA1 domain family, member 2 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB2A | RAB2A, member RAS oncogene family |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RANGRF | RAN guanine nucleotide release factor |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPLP2 | ribosomal protein, large, P2 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM14 | tripartite motif containing 14 |
| TRIM5 | tripartite motif containing 5 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| URI1 | URI1, prefoldin-like chaperone |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZFR | zinc finger RNA binding protein |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ADNP | activity-dependent neuroprotector homeobox |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD49 | ankyrin repeat domain 49 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BLM | Bloom syndrome, RecQ helicase-like |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C2ORF42 | chromosome 2 open reading frame 42 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CDCA4 | cell division cycle associated 4 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CENPE | centromere protein E, 312kDa |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DOLK | dolichol kinase |
| E2F6 | E2F transcription factor 6 |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM50B | family with sequence similarity 50, member B |
| FAM53C | family with sequence similarity 53, member C |
| FANCF | Fanconi anemia, complementation group F |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXO34 | F-box protein 34 |
| FBXO5 | F-box protein 5 |
| FOXD1 | forkhead box D1 |
| FOXK2 | forkhead box K2 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HJURP | Holliday junction recognition protein |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IRS1 | insulin receptor substrate 1 |
| IRX5 | iroquois homeobox 5 |
| JMJD1C | jumonji domain containing 1C |
| KIAA0922 | KIAA0922 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| MED7 | mediator complex subunit 7 |
| METTL18 | methyltransferase like 18 |
| MGA | MGA, MAX dimerization protein |
| MKL2 | MKL/myocardin-like 2 |
| NDC80 | NDC80 kinetochore complex component |
| NPY1R | neuropeptide Y receptor Y1 |
| OSR2 | odd-skipped related transciption factor 2 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PALB2 | partner and localizer of BRCA2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PLK2 | polo-like kinase 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRR15L | proline rich 15-like |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RANBP6 | RAN binding protein 6 |
| RBM7 | RNA binding motif protein 7 |
| RIOK2 | RIO kinase 2 |
| RNF113A | ring finger protein 113A |
| RNMTL1 | RNA methyltransferase like 1 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| SALL2 | spalt-like transcription factor 2 |
| SIRT1 | sirtuin 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor |
| SPATA2L | spermatogenesis associated 2-like |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TBCC | tubulin folding cofactor C |
| TBK1 | TANK-binding kinase 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TRIM32 | tripartite motif containing 32 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TROAP | trophinin associated protein |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSPYL5 | TSPY-like 5 |
| TTK | TTK protein kinase |
| URGCP | upregulator of cell proliferation |
| VANGL1 | VANGL planar cell polarity protein 1 |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF217 | zinc finger protein 217 |
| ZNF232 | zinc finger protein 232 |
| ZNF443 | zinc finger protein 443 |
| ZNF629 | zinc finger protein 629 |
| ZNF84 | zinc finger protein 84 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
