| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the GW-8510-7085 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANAPC5 | anaphase promoting complex subunit 5 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ASRGL1 | asparaginase like 1 |
| ATG13 | autophagy related 13 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BMP1 | bone morphogenetic protein 1 |
| BRD4 | bromodomain containing 4 |
| C3 | complement component 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CALR | calreticulin |
| CCDC176 | coiled-coil domain containing 176 |
| CCPG1 | cell cycle progression 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLSPN | claspin |
| CLTB | clathrin, light chain B |
| CNPY3 | canopy FGF signaling regulator 3 |
| CORT | cortistatin |
| CS | citrate synthase |
| CSNK1E | casein kinase 1, epsilon |
| CUL5 | cullin 5 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 |
| EGR1 | early growth response 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FADS2 | fatty acid desaturase 2 |
| FCMR | Fc fragment of IgM receptor |
| FH | fumarate hydratase |
| FLOT1 | flotillin 1 |
| FN3KRP | fructosamine 3 kinase related protein |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAMT | guanidinoacetate N-methyltransferase |
| GCAT | glycine C-acetyltransferase |
| GLRX3 | glutaredoxin 3 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPX4 | glutathione peroxidase 4 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HTT | huntingtin |
| IFI30 | interferon, gamma-inducible protein 30 |
| IL6 | interleukin 6 |
| JUNB | jun B proto-oncogene |
| KLK6 | kallikrein-related peptidase 6 |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| KRT8P12 | keratin 8 pseudogene 12 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAOA | monoamine oxidase A |
| MED16 | mediator complex subunit 16 |
| MMP1 | matrix metallopeptidase 1 |
| MOSPD3 | motile sperm domain containing 3 |
| MYLK | myosin light chain kinase |
| NMB | neuromedin B |
| NRSN2 | neurensin 2 |
| PCBP4 | poly(rC) binding protein 4 |
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 |
| PDS5A | PDS5 cohesin associated factor A |
| PI3 | peptidase inhibitor 3, skin-derived |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PLXNA1 | plexin A1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 |
| RAB40B | RAB40B, member RAS oncogene family |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL23 | ribosomal protein L23 |
| RPL37A | ribosomal protein L37a |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDF4 | stromal cell derived factor 4 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SNTA1 | syntrophin, alpha 1 |
| SSH3 | slingshot protein phosphatase 3 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STOM | stomatin |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TKFC | triokinase/FMN cyclase |
| TNNI3 | troponin I type 3 (cardiac) |
| TPMT | thiopurine S-methyltransferase |
| TRIM29 | tripartite motif containing 29 |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) |
| UBTD1 | ubiquitin domain containing 1 |
| URI1 | URI1, prefoldin-like chaperone |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZMAT5 | zinc finger, matrin-type 5 |
| Symbol | Name |
|---|---|
| ADNP | activity-dependent neuroprotector homeobox |
| ADRB2 | adrenoceptor beta 2, surface |
| ANKRD49 | ankyrin repeat domain 49 |
| BAG3 | BCL2-associated athanogene 3 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BORA | bora, aurora kinase A activator |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BYSL | bystin-like |
| C14ORF169 | chromosome 14 open reading frame 169 |
| CBR3 | carbonyl reductase 3 |
| CDCA4 | cell division cycle associated 4 |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| COIL | coilin |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTCF | CCCTC-binding factor (zinc finger protein) |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| E2F6 | E2F transcription factor 6 |
| EFNA4 | ephrin-A4 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM46A | family with sequence similarity 46, member A |
| FASTKD5 | FAST kinase domains 5 |
| FBXO34 | F-box protein 34 |
| FEN1 | flap structure-specific endonuclease 1 |
| FZD2 | frizzled class receptor 2 |
| GSPT2 | G1 to S phase transition 2 |
| GTF2B | general transcription factor IIB |
| H1F0 | H1 histone family, member 0 |
| HAS2 | hyaluronan synthase 2 |
| HIRA | histone cell cycle regulator |
| HJURP | Holliday junction recognition protein |
| HMGXB4 | HMG box domain containing 4 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JMJD1C | jumonji domain containing 1C |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 |
| KIFC1 | kinesin family member C1 |
| LEMD3 | LEM domain containing 3 |
| LOC100272216 | uncharacterized LOC100272216 |
| MAD2L1BP | MAD2L1 binding protein |
| MED17 | mediator complex subunit 17 |
| MGA | MGA, MAX dimerization protein |
| MKL2 | MKL/myocardin-like 2 |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| NDC80 | NDC80 kinetochore complex component |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NKRF | NFKB repressing factor |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PLK2 | polo-like kinase 2 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| RANBP6 | RAN binding protein 6 |
| RBM15 | RNA binding motif protein 15 |
| RBM4B | RNA binding motif protein 4B |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RGS2 | regulator of G-protein signaling 2 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RND3 | Rho family GTPase 3 |
| RNF113A | ring finger protein 113A |
| RNF139 | ring finger protein 139 |
| RNF4 | ring finger protein 4 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSBN1 | round spermatid basic protein 1 |
| SEC24B | SEC24 family member B |
| SLC38A2 | solute carrier family 38, member 2 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SUV420H1 | suppressor of variegation 4-20 homolog 1 (Drosophila) |
| TBCC | tubulin folding cofactor C |
| TBX3 | T-box 3 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TOB1 | transducer of ERBB2, 1 |
| TRIB1 | tribbles pseudokinase 1 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSPYL5 | TSPY-like 5 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF12 | zinc finger protein 12 |
| ZNF217 | zinc finger protein 217 |
| ZNF281 | zinc finger protein 281 |
| ZNF443 | zinc finger protein 443 |
| ZNF672 | zinc finger protein 672 |
| ZNF7 | zinc finger protein 7 |
