Gallic acid (hydrate)_A-172 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in A-172 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.179424
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.15306
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.136401
COL8A1 collagen, type VIII, alpha 1 0.122838
CDH13 cadherin 13 0.105603
PLAT plasminogen activator, tissue 0.0980656
LOX lysyl oxidase 0.0894163
VIM vimentin 0.0885091
IGFBP3 insulin-like growth factor binding protein 3 0.0883676
ZBTB20 zinc finger and BTB domain containing 20 0.0738119
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0690247
TMSB10 thymosin beta 10 0.0682263
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0677301
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.0665207
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0601413
MYADM myeloid-associated differentiation marker 0.057965
DST dystonin 0.055643
PDE4D phosphodiesterase 4D, cAMP-specific 0.0547965
ASPH aspartate beta-hydroxylase 0.0539402
EFNA5 ephrin-A5 0.0522952
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.0517908
NAV1 neuron navigator 1 0.0468802
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0454783
MT2A metallothionein 2A 0.0454064
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0451101
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0445707
ARL15 ADP-ribosylation factor-like 15 0.0433391
AUTS2 autism susceptibility candidate 2 0.0397234
AHNAK AHNAK nucleoprotein 0.039078
ERRFI1 ERBB receptor feedback inhibitor 1 0.0386701
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0385774
COL5A2 collagen, type V, alpha 2 0.0374995
PGK1 phosphoglycerate kinase 1 0.0374025
FBN1 fibrillin 1 0.0373345
COL1A2 collagen, type I, alpha 2 0.0370609
PRELID2 PRELI domain containing 2 0.0366636
RASAL2 RAS protein activator like 2 0.0357898
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0356316
FRMD4A FERM domain containing 4A 0.0352924
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0348079
INTS6 integrator complex subunit 6 0.0338394
LPP LIM domain containing preferred translocation partner in lipoma 0.0335819
CANX calnexin 0.0331276
PRSS23 protease, serine, 23 0.0330042
VCL vinculin 0.0329467
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0324688
CYTH3 cytohesin 3 0.0323528
MAP1B microtubule-associated protein 1B 0.0319976
EHBP1 EH domain binding protein 1 0.0315706
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0307335
SOD2 superoxide dismutase 2, mitochondrial 0.0306896
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0305188
GLIS3 GLIS family zinc finger 3 0.0303436
COL3A1 collagen, type III, alpha 1 0.0296719
SP100 SP100 nuclear antigen 0.0294776
FRMD5 FERM domain containing 5 0.0283478
PSD3 pleckstrin and Sec7 domain containing 3 0.0283324
SDCCAG8 serologically defined colon cancer antigen 8 0.0281977
SAMD9 sterile alpha motif domain containing 9 0.028142
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0281104
PODXL podocalyxin-like 0.0279964
PARP14 poly (ADP-ribose) polymerase family, member 14 0.027375
APP amyloid beta (A4) precursor protein 0.0269142
SH3KBP1 SH3-domain kinase binding protein 1 0.0268785
JAZF1 JAZF zinc finger 1 0.0268153
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0266893
LDHA lactate dehydrogenase A 0.0264264
HDAC9 histone deacetylase 9 0.0263056
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0260435
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0258553
MBD5 methyl-CpG binding domain protein 5 0.0257863
MRPS6 mitochondrial ribosomal protein S6 0.0256153
DGKG diacylglycerol kinase, gamma 90kDa 0.0251208
SYT1 synaptotagmin I 0.0248888
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0247917
CD59 CD59 molecule, complement regulatory protein 0.0243242
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0242305
CEP170 centrosomal protein 170kDa 0.0241681
ARB2A ARB2 cotranscriptional regulator A 0.0241217
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0236665
CHD9 chromodomain helicase DNA binding protein 9 0.0235746
FNDC3B fibronectin type III domain containing 3B 0.0234984
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0231198
NEK7 NIMA-related kinase 7 0.0229755
CD44 CD44 molecule (Indian blood group) 0.0228986
DDR2 discoidin domain receptor tyrosine kinase 2 0.0226195
EGFR epidermal growth factor receptor 0.0224648
ALCAM activated leukocyte cell adhesion molecule 0.0223006
ZEB1 zinc finger E-box binding homeobox 1 0.0219507
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.0218759
DHRSX dehydrogenase/reductase (SDR family) X-linked 0.0218429
MACF1 microtubule-actin crosslinking factor 1 0.0217339
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.0214853
DOCK5 dedicator of cytokinesis 5 0.0212928
NBEAL1 neurobeachin-like 1 0.021291
MYOF myoferlin 0.0211576
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0211564
ANXA1 annexin A1 0.0210468
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0209584
MBNL1 muscleblind-like splicing regulator 1 0.0208264

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.118582
NDRG1 N-myc downstream regulated 1 -0.0675973
FOSL1 FOS-like antigen 1 -0.0476233
SQSTM1 sequestosome 1 -0.0451003
P4HB prolyl 4-hydroxylase, beta polypeptide -0.04353
RHOBTB3 Rho-related BTB domain containing 3 -0.0406587
POTEF POTE ankyrin domain family, member F -0.0392154
CCND1 cyclin D1 -0.0391714
BHLHE40 basic helix-loop-helix family, member e40 -0.0391524
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0388764
TRIO trio Rho guanine nucleotide exchange factor -0.0377743
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0372597
GOLGA4 golgin A4 -0.0365492
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0355708
S100A10 S100 calcium binding protein A10 -0.0355276
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -0.0321627
CD109 CD109 molecule -0.0308851
DDIT4 DNA-damage-inducible transcript 4 -0.0304165
MEIS2 Meis homeobox 2 -0.0303648
ZMIZ1 zinc finger, MIZ-type containing 1 -0.0276438
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0275903
ULK1 unc-51 like autophagy activating kinase 1 -0.027131
FTL ferritin, light polypeptide -0.026035
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0253095
DCLK2 doublecortin-like kinase 2 -0.0243798
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.0239348
RAB7A RAB7A, member RAS oncogene family -0.0238014
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0236287
ACTG1 actin gamma 1 -0.0234718
ADM adrenomedullin -0.023455
LOC112694756 uncharaterized LOC112694756 -0.0226066
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -0.0223026
MSI2 musashi RNA-binding protein 2 -0.0222689
RNMT RNA (guanine-7-) methyltransferase -0.0221589
OGA O-GlcNAcase -0.0219064
PTMA prothymosin, alpha -0.0218239
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0215261
RFX2 regulatory factor X, 2 (influences HLA class II expression) -0.0213811
RPL28 ribosomal protein L28 -0.0208245
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0205769
WSB1 WD repeat and SOCS box containing 1 -0.0204291
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0197641
RPL35A ribosomal protein L35a -0.0197077
RPLP1 ribosomal protein, large, P1 -0.0195607
ZMYND8 zinc finger, MYND-type containing 8 -0.0194236
HILPDA hypoxia inducible lipid droplet-associated -0.0193921
S100A6 S100 calcium binding protein A6 -0.0192385
FLNA filamin A, alpha -0.01912
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0191093
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.0190315
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0188105
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0186542
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0185594
GADD45A growth arrest and DNA-damage-inducible, alpha -0.018486
FGFR1 fibroblast growth factor receptor 1 -0.0178751
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0177976
MXI1 MAX interactor 1, dimerization protein -0.0177864
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.0169071
RPS6 ribosomal protein S6 -0.0168257
WDR45B WD repeat domain 45B -0.0166696
GADD45B growth arrest and DNA-damage-inducible, beta -0.0166527
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.0165543
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0163233
ANKRD11 ankyrin repeat domain 11 -0.0163194
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0162508
ACTN4 actinin, alpha 4 -0.0160992
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0160952
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0159075
HSPB1 heat shock 27kDa protein 1 -0.0158816
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.0152422
FTH1 ferritin, heavy polypeptide 1 -0.0152158
ADAM9 ADAM metallopeptidase domain 9 -0.0152005
RND3 Rho family GTPase 3 -0.0151149
LMNA lamin A/C -0.0149113
ESYT2 extended synaptotagmin-like protein 2 -0.0147555
RRBP1 ribosome binding protein 1 -0.0147218
HELZ helicase with zinc finger -0.0145563
DLG1 discs, large homolog 1 (Drosophila) -0.0145465
ZFP36 ZFP36 ring finger protein -0.014544
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0145087
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0144899
KDM7A lysine (K)-specific demethylase 7A -0.0144586
XPO6 exportin 6 -0.0143169
MEF2D myocyte enhancer factor 2D -0.0142363
SERTAD2 SERTA domain containing 2 -0.014229
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0142091
ADAM17 ADAM metallopeptidase domain 17 -0.0141854
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -0.0141586
SHB Src homology 2 domain containing adaptor protein B -0.0140614
LOC102724023 ES1 protein homolog, mitochondrial -0.0138892
MNT MAX network transcriptional repressor -0.0138632
PER1 period circadian clock 1 -0.0137179
NCOR2 nuclear receptor corepressor 2 -0.0137173
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0136345
IFITM3 interferon induced transmembrane protein 3 -0.0135851
MATR3 matrin 3 -0.0135847
SEC61G Sec61 gamma subunit -0.0135831
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0135559
IARS1 isoleucyl-tRNA synthetase 1 -0.0135425
SPNS2 spinster homolog 2 (Drosophila) -0.0135333