Gallic acid (hydrate)_A-427 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in A-427 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.165653
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.133403
STARD4 StAR-related lipid transfer (START) domain containing 4 0.109786
NAP1L1 nucleosome assembly protein 1-like 1 0.104932
RPS2 ribosomal protein S2 0.0880867
TMEM41B transmembrane protein 41B 0.0843152
ANXA1 annexin A1 0.0839433
ERRFI1 ERBB receptor feedback inhibitor 1 0.0798297
RPS12 ribosomal protein S12 0.079067
MMP12 matrix metallopeptidase 12 0.0772728
KIF5B kinesin family member 5B 0.0758344
RPL26 ribosomal protein L26 0.0719044
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0716954
TPT1 tumor protein, translationally-controlled 1 0.0707389
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0707214
PTMA prothymosin, alpha 0.0704533
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0700457
VIM vimentin 0.0685192
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0679386
ASPH aspartate beta-hydroxylase 0.0608245
RPS3 ribosomal protein S3 0.0601716
RPL23 ribosomal protein L23 0.055207
MYL12B myosin, light chain 12B, regulatory 0.0546328
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.053485
AKAP12 A kinase (PRKA) anchor protein 12 0.0507311
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0503019
BIRC2 baculoviral IAP repeat containing 2 0.0501656
NIPBL Nipped-B homolog (Drosophila) 0.0496358
JMJD1C jumonji domain containing 1C 0.049556
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0458877
YBX3 Y box binding protein 3 0.0455415
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0450222
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0445877
CSNK1A1 casein kinase 1, alpha 1 0.0439172
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0436126
TPM3 tropomyosin 3 0.0434808
KDM3A lysine (K)-specific demethylase 3A 0.043412
CLTC clathrin, heavy chain (Hc) 0.0429765
IFIH1 interferon induced with helicase C domain 1 0.042707
SET SET nuclear proto-oncogene 0.0423871
SPATS2 spermatogenesis associated, serine-rich 2 0.0421537
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0421036
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0407829
NCAPD2 non-SMC condensin I complex, subunit D2 0.0402837
DST dystonin 0.0391017
ANKRD12 ankyrin repeat domain 12 0.0390458
TPI1 triosephosphate isomerase 1 0.0389533
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0389415
PUM2 pumilio RNA-binding family member 2 0.0389323
RPS7 ribosomal protein S7 0.0387219
RPS8 ribosomal protein S8 0.0381498
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0376357
VMP1 vacuole membrane protein 1 0.0370553
CKAP5 cytoskeleton associated protein 5 0.0368628
RRM2 ribonucleotide reductase M2 0.0365351
HLTF helicase-like transcription factor 0.0363527
CENPF centromere protein F, 350/400kDa 0.0349749
LMO7 LIM domain 7 0.0345575
ENO1 enolase 1, (alpha) 0.0342925
EZR ezrin 0.0329672
BIRC6 baculoviral IAP repeat containing 6 0.0329581
OSBPL8 oxysterol binding protein-like 8 0.0320898
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0319438
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.0317975
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0294274
RPL37A ribosomal protein L37a 0.0293781
IL6ST interleukin 6 signal transducer 0.0292839
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0291651
IPO7 importin 7 0.0289952
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0286749
PGK1 phosphoglycerate kinase 1 0.0281579
RBM39 RNA binding motif protein 39 0.0281204
NCOR1 nuclear receptor corepressor 1 0.0276813
DSPP dentin sialophosphoprotein 0.0274056
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0271922
HSPA8 heat shock 70kDa protein 8 0.0268779
TOP2B topoisomerase (DNA) II beta 180kDa 0.0268616
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.0267992
CLDN1 claudin 1 0.0264855
CHD4 chromodomain helicase DNA binding protein 4 0.0264748
CARD16 caspase recruitment domain family, member 16 0.0264645
RAB10 RAB10, member RAS oncogene family 0.0262082
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0261681
MACF1 microtubule-actin crosslinking factor 1 0.026148
EIF4A2 eukaryotic translation initiation factor 4A2 0.0259631
NARS1 asparaginyl-tRNA synthetase 1 0.0256672
SPAG9 sperm associated antigen 9 0.0256463
DPYD dihydropyrimidine dehydrogenase 0.02535
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0253153
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.0252184
RPS27A ribosomal protein S27a 0.0250468
HDGF hepatoma-derived growth factor 0.0248735
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0245555
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.024521
CDK17 cyclin-dependent kinase 17 0.0243754
TNPO1 transportin 1 0.0243379
ANKHD1 ankyrin repeat and KH domain containing 1 0.0241285
THRAP3 thyroid hormone receptor associated protein 3 0.0239137
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0238686
HSPE1 heat shock 10kDa protein 1 0.0237395

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.273764
NLGN1 neuroligin 1 -0.0585698
ATP5F1B ATP synthase F1 subunit beta -0.0456736
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0423645
TMSB10 thymosin beta 10 -0.0415645
CNRIP1 cannabinoid receptor interacting protein 1 -0.0414871
ACTG1 actin gamma 1 -0.0400727
RPS23 ribosomal protein S23 -0.0395697
EGR1 early growth response 1 -0.0389231
RPS15 ribosomal protein S15 -0.0384439
HLA-A major histocompatibility complex, class I, A -0.0368282
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0357938
HMGA1 high mobility group AT-hook 1 -0.0336215
RPS19 ribosomal protein S19 -0.0333443
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0325935
PDE4D phosphodiesterase 4D, cAMP-specific -0.0323575
PCBP2 poly(rC) binding protein 2 -0.0314223
RPL28 ribosomal protein L28 -0.0306551
RPLP1 ribosomal protein, large, P1 -0.0303222
POTEF POTE ankyrin domain family, member F -0.0293203
HSPB1 heat shock 27kDa protein 1 -0.0277327
RPS6 ribosomal protein S6 -0.026743
FTL ferritin, light polypeptide -0.025481
WWOX WW domain containing oxidoreductase -0.0247183
HMGA2 high mobility group AT-hook 2 -0.0245389
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0238256
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.023776
FTH1 ferritin, heavy polypeptide 1 -0.0222299
PFN1 profilin 1 -0.0215651
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -0.0211582
EEF2 eukaryotic translation elongation factor 2 -0.0211572
NHSL1 NHS-like 1 -0.0210484
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0207322
INTS6 integrator complex subunit 6 -0.020606
ZBTB20 zinc finger and BTB domain containing 20 -0.0205518
TENM3 teneurin transmembrane protein 3 -0.0201592
RPL35A ribosomal protein L35a -0.0201029
RPS20 ribosomal protein S20 -0.0196844
RPL8 ribosomal protein L8 -0.019445
RPS11 ribosomal protein S11 -0.0193188
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.0190747
AREG amphiregulin -0.0185339
CCN2 cellular communication network factor 2 -0.0184699
ZNF207 zinc finger protein 207 -0.018073
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1 -0.0180031
ATN1 atrophin 1 -0.0178675
ANKRD28 ankyrin repeat domain 28 -0.0174179
LRRTM4 leucine rich repeat transmembrane neuronal 4 -0.0170964
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0168934
FASN fatty acid synthase -0.0168748
MEF2D myocyte enhancer factor 2D -0.0167589
TGM2 transglutaminase 2 -0.0167413
RPL32 ribosomal protein L32 -0.0165391
ZNF638 zinc finger protein 638 -0.0164527
ARF3 ADP-ribosylation factor 3 -0.0157737
EEF1G eukaryotic translation elongation factor 1 gamma -0.0157736
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.0149667
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0148403
RPS4X ribosomal protein S4, X-linked -0.0147462
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0146838
RPS5 ribosomal protein S5 -0.0146698
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0143935
FOXM1 forkhead box M1 -0.0142875
FUS FUS RNA binding protein -0.0142699
DEK DEK proto-oncogene -0.0140835
TAPBP TAP binding protein (tapasin) -0.0139418
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0138998
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0138561
GSE1 Gse1 coiled-coil protein -0.0133619
L3MBTL4 l(3)mbt-like 4 (Drosophila) -0.0132389
HCFC1 host cell factor C1 -0.0131271
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0131118
GNAS GNAS complex locus -0.0131098
ATP5MC2 ATP synthase membrane subunit c locus 2 -0.0130027
HELLS helicase, lymphoid-specific -0.0129958
S100A10 S100 calcium binding protein A10 -0.0129784
RBMX RNA binding motif protein, X-linked -0.0127671
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.0125778
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0125556
TBCB tubulin folding cofactor B -0.0125296
EP400 E1A binding protein p400 -0.0125069
YAP1 Yes-associated protein 1 -0.0124159
MED26 mediator complex subunit 26 -0.0124015
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -0.0122611
SMC4 structural maintenance of chromosomes 4 -0.0122328
RIMS2 regulating synaptic membrane exocytosis 2 -0.0120854
S100A9 S100 calcium binding protein A9 -0.012038
SMIM44 small integral membrane protein 44 -0.0120089
LENG8 leukocyte receptor cluster (LRC) member 8 -0.0120023
RNPS1 RNA binding protein S1, serine-rich domain -0.0118896
MBD6 methyl-CpG binding domain protein 6 -0.0118514
CCND1 cyclin D1 -0.0117553
BPTF bromodomain PHD finger transcription factor -0.0115535
RPS27 ribosomal protein S27 -0.0114335
KDM4C lysine (K)-specific demethylase 4C -0.0114026
TBCA tubulin folding cofactor A -0.01139
NUDCD2 NudC domain containing 2 -0.0113296
NCOA7 nuclear receptor coactivator 7 -0.0112284
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -0.0112089
FNDC3B fibronectin type III domain containing 3B -0.0112021