Gallic acid (hydrate)_A549 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in A549 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.151895
FTL ferritin, light polypeptide 0.134418
RPLP1 ribosomal protein, large, P1 0.093414
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.090575
RPS6 ribosomal protein S6 0.0891884
ACTG1 actin gamma 1 0.0830611
FTH1 ferritin, heavy polypeptide 1 0.0692441
PDE4D phosphodiesterase 4D, cAMP-specific 0.066435
IGFBP3 insulin-like growth factor binding protein 3 0.0618777
BHLHE40 basic helix-loop-helix family, member e40 0.0566919
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0487568
TPT1 tumor protein, translationally-controlled 1 0.0486993
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0462878
ANXA2 annexin A2 0.0455424
MYO1E myosin IE 0.0449508
RPL12 ribosomal protein L12 0.0441419
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0437704
EFNA5 ephrin-A5 0.0437421
BZW1 basic leucine zipper and W2 domains 1 0.0433343
ERRFI1 ERBB receptor feedback inhibitor 1 0.0428392
RPS19 ribosomal protein S19 0.0422103
ZSWIM6 zinc finger, SWIM-type containing 6 0.0421435
THSD4 thrombospondin, type I, domain containing 4 0.0420097
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0407877
RPLP0 ribosomal protein, large, P0 0.0389738
S100A10 S100 calcium binding protein A10 0.0381037
EPAS1 endothelial PAS domain protein 1 0.0380472
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0374563
PDLIM5 PDZ and LIM domain 5 0.0371663
TKT transketolase 0.0365558
USP3 ubiquitin specific peptidase 3 0.0364318
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.036344
EXT1 exostosin glycosyltransferase 1 0.0362537
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0357431
VCL vinculin 0.0352334
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0338658
RPS8 ribosomal protein S8 0.033206
NRIP1 nuclear receptor interacting protein 1 0.0330939
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0327878
RASA2 RAS p21 protein activator 2 0.0325078
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.032122
RPL34 ribosomal protein L34 0.0318533
RPL26 ribosomal protein L26 0.0309609
RPL35A ribosomal protein L35a 0.0307782
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.0302767
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0299656
ALCAM activated leukocyte cell adhesion molecule 0.0298269
RPS24 ribosomal protein S24 0.0292884
RPS16 ribosomal protein S16 0.0292395
INTS6 integrator complex subunit 6 0.0290654
RPL13A ribosomal protein L13a 0.0285668
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0280064
NAP1L1 nucleosome assembly protein 1-like 1 0.0267735
ZC3H12C zinc finger CCCH-type containing 12C 0.0254065
RPS2 ribosomal protein S2 0.0252502
RPL38 ribosomal protein L38 0.0248329
GRB10 growth factor receptor-bound protein 10 0.0246297
AADAC arylacetamide deacetylase 0.0244848
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.0244726
BAIAP2L1 BAI1-associated protein 2-like 1 0.0243663
IER3 immediate early response 3 0.0243164
SPAG9 sperm associated antigen 9 0.0238569
MAML3 mastermind-like 3 (Drosophila) 0.0234294
TGFBR1 transforming growth factor, beta receptor 1 0.0233902
RPL11 ribosomal protein L11 0.0232391
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0227064
KLF6 Kruppel-like factor 6 0.0226708
FBXO11 F-box protein 11 0.0225307
RPL35 ribosomal protein L35 0.0221362
ARHGAP5 Rho GTPase activating protein 5 0.0217271
USP53 ubiquitin specific peptidase 53 0.0217112
LMO7 LIM domain 7 0.0217106
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0216608
BMP6 bone morphogenetic protein 6 0.0215232
LOXL2 lysyl oxidase-like 2 0.0212641
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0211093
ARF1 ADP-ribosylation factor 1 0.0209636
TRA2A transformer 2 alpha homolog (Drosophila) 0.0208976
NTN4 netrin 4 0.0204379
KANK1 KN motif and ankyrin repeat domains 1 0.0200465
RPL27A ribosomal protein L27a 0.0197887
DUSP16 dual specificity phosphatase 16 0.019602
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 0.0195825
KRT18 keratin 18, type I 0.0195423
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0193956
RPL39 ribosomal protein L39 0.0193722
TFPI2 tissue factor pathway inhibitor 2 0.0190727
AGO2 argonaute RISC catalytic component 2 0.0190065
RPS20 ribosomal protein S20 0.0186783
SQSTM1 sequestosome 1 0.0186621
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0186273
DSPP dentin sialophosphoprotein 0.0180473
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0177568
LIMCH1 LIM and calponin homology domains 1 0.017667
COTL1 coactosin-like F-actin binding protein 1 0.0176581
RPS21 ribosomal protein S21 0.017652
PCSK5 proprotein convertase subtilisin/kexin type 5 0.0176477
HMGA2 high mobility group AT-hook 2 0.017638
FBXL2 F-box and leucine-rich repeat protein 2 0.017618
DOCK5 dedicator of cytokinesis 5 0.0174008

decreased expression

Symbol Name Standardized Value
UBC ubiquitin C -0.143194
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0929883
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0905294
VIM vimentin -0.0838325
PCBP2 poly(rC) binding protein 2 -0.0805063
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0770654
RPS27A ribosomal protein S27a -0.0750445
MT2A metallothionein 2A -0.0653556
NDRG1 N-myc downstream regulated 1 -0.0651834
EEF2 eukaryotic translation elongation factor 2 -0.0646906
TXNRD1 thioredoxin reductase 1 -0.059859
TMSB10 thymosin beta 10 -0.0548265
AXL AXL receptor tyrosine kinase -0.0505813
CMIP c-Maf inducing protein -0.0496223
MCL1 myeloid cell leukemia 1 -0.0489194
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0456239
FLNB filamin B, beta -0.0455122
POTEF POTE ankyrin domain family, member F -0.0430504
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0427636
MYADM myeloid-associated differentiation marker -0.0405094
CD44 CD44 molecule (Indian blood group) -0.0401217
SRRM2 serine/arginine repetitive matrix 2 -0.0396726
ARHGAP26 Rho GTPase activating protein 26 -0.0393901
ENO1 enolase 1, (alpha) -0.0392526
RTN4 reticulon 4 -0.0391275
PKM pyruvate kinase, muscle -0.0389139
DGKD diacylglycerol kinase, delta 130kDa -0.0377825
CA12 carbonic anhydrase XII -0.0371455
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0365453
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0357057
CENPF centromere protein F, 350/400kDa -0.0330029
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0322976
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.0316328
LDHA lactate dehydrogenase A -0.0311698
EIF4A1 eukaryotic translation initiation factor 4A1 -0.030664
TM4SF1 transmembrane 4 L six family member 1 -0.0306057
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0294967
MT1X metallothionein 1X -0.0292654
MAP1B microtubule-associated protein 1B -0.0289702
MSN moesin -0.0280874
SPDYA speedy/RINGO cell cycle regulator family member A -0.0273639
IGFBP4 insulin-like growth factor binding protein 4 -0.0268179
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0266818
FLNA filamin A, alpha -0.026654
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0262079
RNF213 ring finger protein 213 -0.0259825
MKI67 marker of proliferation Ki-67 -0.025757
TRIM25 tripartite motif containing 25 -0.0253499
TPM3 tropomyosin 3 -0.0252536
TNIP1 TNFAIP3 interacting protein 1 -0.025249
CALU calumenin -0.0248576
AHNAK AHNAK nucleoprotein -0.0248146
CCNL1 cyclin L1 -0.0245703
URI1 URI1, prefoldin-like chaperone -0.0242933
PRRC2C proline-rich coiled-coil 2C -0.0242206
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0240711
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0237547
LAMA5 laminin, alpha 5 -0.0236124
C1D C1D nuclear receptor corepressor -0.0236042
LTBP4 latent transforming growth factor beta binding protein 4 -0.0235985
ADAM9 ADAM metallopeptidase domain 9 -0.0234174
GGNBP2 gametogenetin binding protein 2 -0.0233742
HDGF hepatoma-derived growth factor -0.023155
THOC2 THO complex 2 -0.0227193
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0226543
FAM107B family with sequence similarity 107, member B -0.0222908
SLC38A2 solute carrier family 38, member 2 -0.0220764
EIF3M eukaryotic translation initiation factor 3, subunit M -0.0219126
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0217472
IFI6 interferon, alpha-inducible protein 6 -0.0216117
ENO2 enolase 2 (gamma, neuronal) -0.0209669
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.020912
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.0208028
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0206289
PDE4B phosphodiesterase 4B, cAMP-specific -0.0205189
TBK1 TANK-binding kinase 1 -0.0205088
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0204869
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0203061
ZMYND8 zinc finger, MYND-type containing 8 -0.0202256
NRP1 neuropilin 1 -0.0202043
AKR1C2 aldo-keto reductase family 1, member C2 -0.02013
SBF2 SET binding factor 2 -0.0200919
PDIA6 protein disulfide isomerase family A, member 6 -0.0200228
BIRC6 baculoviral IAP repeat containing 6 -0.0196579
RIGI RNA sensor RIG-I -0.0195004
PCM1 pericentriolar material 1 -0.0194672
SRPK1 SRSF protein kinase 1 -0.0194241
DSTN destrin (actin depolymerizing factor) -0.0192734
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0191577
SMG6 SMG6 nonsense mediated mRNA decay factor -0.0191413
CFLAR CASP8 and FADD-like apoptosis regulator -0.0191002
SFPQ splicing factor proline/glutamine-rich -0.0190356
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0190143
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.0189769
SIN3A SIN3 transcription regulator family member A -0.0189284
NAMPT nicotinamide phosphoribosyltransferase -0.0188801
SRSF11 serine/arginine-rich splicing factor 11 -0.0188631
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -0.0188371
MX1 MX dynamin-like GTPase 1 -0.018712
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0185477