Gallic acid (hydrate)_AsPC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LAMB3 laminin, beta 3 0.0631071
ERRFI1 ERBB receptor feedback inhibitor 1 0.0620871
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.062058
ASPH aspartate beta-hydroxylase 0.0487256
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0427749
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0415981
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0370132
BZW1 basic leucine zipper and W2 domains 1 0.0330372
HSPA8 heat shock 70kDa protein 8 0.0295351
OGA O-GlcNAcase 0.0282344
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0278175
MMP1 matrix metallopeptidase 1 0.0275017
DSPP dentin sialophosphoprotein 0.0265134
GDA guanine deaminase 0.0248953
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 0.0247925
TRIO trio Rho guanine nucleotide exchange factor 0.0237108
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0230363
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0216762
CD44 CD44 molecule (Indian blood group) 0.0211175
AHNAK2 AHNAK nucleoprotein 2 0.0208738
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0208423
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.01986
INTS6 integrator complex subunit 6 0.0195324
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0192648
KDM3A lysine (K)-specific demethylase 3A 0.019064
CAPRIN2 caprin family member 2 0.0187402
LAMC2 laminin, gamma 2 0.018439
RAI14 retinoic acid induced 14 0.018342
SRRM2 serine/arginine repetitive matrix 2 0.0174791
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0167842
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0164419
RPS7 ribosomal protein S7 0.0159317
ZC3H3 zinc finger CCCH-type containing 3 0.0155892
SMAD3 SMAD family member 3 0.0155373
DST dystonin 0.0154979
FMNL2 formin-like 2 0.0154541
SERINC1 serine incorporator 1 0.0154392
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0153638
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0153271
BAIAP2L1 BAI1-associated protein 2-like 1 0.0149892
NAP1L1 nucleosome assembly protein 1-like 1 0.0146338
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0145755
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0144243
ANO6 anoctamin 6 0.0141829
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0141746
LPP LIM domain containing preferred translocation partner in lipoma 0.0140996
FN1 fibronectin 1 0.0140661
BMP6 bone morphogenetic protein 6 0.0137714
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0137465
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0137373
SAMD9 sterile alpha motif domain containing 9 0.0136609
KDM7A lysine (K)-specific demethylase 7A 0.0129829
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0129207
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.0127454
SH3KBP1 SH3-domain kinase binding protein 1 0.0125822
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.012531
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.012473
ANKLE2 ankyrin repeat and LEM domain containing 2 0.0124238
NRIP1 nuclear receptor interacting protein 1 0.0123917
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0123541
FAM110C family with sequence similarity 110, member C 0.01228
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0122189
TARS1 threonyl-tRNA synthetase 1 0.0121732
PHF3 PHD finger protein 3 0.0120978
RAD50 RAD50 homolog (S. cerevisiae) 0.0120781
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0118907
ENO1 enolase 1, (alpha) 0.0118804
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0118635
AHR aryl hydrocarbon receptor 0.0117424
CAPN2 calpain 2, (m/II) large subunit 0.0116956
CSTB cystatin B (stefin B) 0.0116771
CANX calnexin 0.0116763
DENR density-regulated protein 0.0114812
SERINC5 serine incorporator 5 0.0113163
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.0112661
TCEA1 transcription elongation factor A (SII), 1 0.0111626
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.0111107
ZRANB2 zinc finger, RAN-binding domain containing 2 0.010944
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0108819
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0108369
ARF1 ADP-ribosylation factor 1 0.0107198
FGFR1 fibroblast growth factor receptor 1 0.0106874
EXT1 exostosin glycosyltransferase 1 0.0105748
PRELID2 PRELI domain containing 2 0.0105255
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 0.01042
CAB39 calcium binding protein 39 0.0103829
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0103766
IMMT inner membrane protein, mitochondrial 0.0101688
RPL4 ribosomal protein L4 0.0100365
MYH9 myosin, heavy chain 9, non-muscle 0.00998155
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.00998081
CCDC68 coiled-coil domain containing 68 0.00988067
RB1 retinoblastoma 1 0.0098607
ZFAND3 zinc finger, AN1-type domain 3 0.00984697
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0097937
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00970007
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00967621
ACIN1 apoptotic chromatin condensation inducer 1 0.00965531
FERMT1 fermitin family member 1 0.00964833
ARHGAP29 Rho GTPase activating protein 29 0.00955599

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.316874
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.22164
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.219838
FTH1 ferritin, heavy polypeptide 1 -0.147435
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.137848
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.120941
HMGA1 high mobility group AT-hook 1 -0.110857
FLNB filamin B, beta -0.105999
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0975559
B2M beta-2-microglobulin -0.0942535
EZR ezrin -0.0913724
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0892766
F3 coagulation factor III (thromboplastin, tissue factor) -0.0891622
MUC17 mucin 17, cell surface associated -0.0774272
LY6E lymphocyte antigen 6 complex, locus E -0.0773341
LMTK2 lemur tyrosine kinase 2 -0.0726006
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.0710256
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0709043
RPS21 ribosomal protein S21 -0.070793
POTEF POTE ankyrin domain family, member F -0.0706627
LMO7 LIM domain 7 -0.0688227
ARF4 ADP-ribosylation factor 4 -0.0675628
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0668599
TXNIP thioredoxin interacting protein -0.0646226
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.0613858
DIAPH1 diaphanous-related formin 1 -0.0584921
EGFR epidermal growth factor receptor -0.0579085
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0577913
GREB1L growth regulation by estrogen in breast cancer-like -0.05646
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0540629
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.053361
AKAP9 A kinase (PRKA) anchor protein 9 -0.0504094
FAM3C family with sequence similarity 3, member C -0.049527
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0491884
VIM vimentin -0.0491003
RPL8 ribosomal protein L8 -0.0489845
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0484535
AKAP12 A kinase (PRKA) anchor protein 12 -0.046973
EGR1 early growth response 1 -0.04632
PTMA prothymosin, alpha -0.0456699
JUP junction plakoglobin -0.0452064
DOCK5 dedicator of cytokinesis 5 -0.0441931
ANTXR2 anthrax toxin receptor 2 -0.0439458
ACTN4 actinin, alpha 4 -0.0435883
RPS27 ribosomal protein S27 -0.0432907
RIOK3 RIO kinase 3 -0.0432755
PTPRR protein tyrosine phosphatase, receptor type, R -0.0428589
UBE2H ubiquitin-conjugating enzyme E2H -0.0415166
CD59 CD59 molecule, complement regulatory protein -0.0414332
ESYT2 extended synaptotagmin-like protein 2 -0.0411622
OXSR1 oxidative stress responsive 1 -0.0411393
TRRAP transformation/transcription domain-associated protein -0.0402427
FTL ferritin, light polypeptide -0.0399881
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0397966
FOSL1 FOS-like antigen 1 -0.0397875
PCBP2 poly(rC) binding protein 2 -0.0396573
GNAS GNAS complex locus -0.0391098
RAP1B RAP1B, member of RAS oncogene family -0.0389965
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0387134
WASF2 WAS protein family, member 2 -0.0386049
RABGAP1L RAB GTPase activating protein 1-like -0.038488
SMC3 structural maintenance of chromosomes 3 -0.0383477
MIDN midnolin -0.0383248
RPLP2 ribosomal protein, large, P2 -0.0381777
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0381193
TAOK3 TAO kinase 3 -0.0379129
RPL23 ribosomal protein L23 -0.0376306
EPHA2 EPH receptor A2 -0.0369706
ADAM9 ADAM metallopeptidase domain 9 -0.0368014
VCAN versican -0.0365562
MXD1 MAX dimerization protein 1 -0.0364818
IFI6 interferon, alpha-inducible protein 6 -0.0361417
RCOR1 REST corepressor 1 -0.0358952
PARD3 par-3 family cell polarity regulator -0.0355612
GUK1 guanylate kinase 1 -0.0355068
SEC31A SEC31 homolog A (S. cerevisiae) -0.0351753
S100A11 S100 calcium binding protein A11 -0.0350246
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0349999
S100A4 S100 calcium binding protein A4 -0.0349669
FBXO11 F-box protein 11 -0.0348165
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0343553
BIRC6 baculoviral IAP repeat containing 6 -0.0341815
RPL34 ribosomal protein L34 -0.03407
MAML2 mastermind-like 2 (Drosophila) -0.0338319
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0336827
RPS13 ribosomal protein S13 -0.0334388
PFN1 profilin 1 -0.0329949
PRRC2C proline-rich coiled-coil 2C -0.0327387
SKAP2 src kinase associated phosphoprotein 2 -0.0326332
CLMP CXADR-like membrane protein -0.0325336
SEM1 SEM1 26S proteasome subunit -0.0324894
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0324439
PPARD peroxisome proliferator-activated receptor delta -0.0324434
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0323885
FOXO3 forkhead box O3 -0.032384
TPM4 tropomyosin 4 -0.0322947
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0320448
TJP1 tight junction protein 1 -0.0319569
STK39 serine threonine kinase 39 -0.0318689
ANXA11 annexin A11 -0.0318217