Gallic acid (hydrate)_C-33 A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in C-33 A cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.089637
KDM3A lysine (K)-specific demethylase 3A 0.073207
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.072362
PTMA prothymosin, alpha 0.0684525
RPS12 ribosomal protein S12 0.0661752
JMJD1C jumonji domain containing 1C 0.0606429
ASPH aspartate beta-hydroxylase 0.0604703
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0569427
KMT2C lysine (K)-specific methyltransferase 2C 0.0555313
RPL23 ribosomal protein L23 0.0549324
CANX calnexin 0.0545679
RPS6 ribosomal protein S6 0.0545633
OGA O-GlcNAcase 0.0540696
GOLGA4 golgin A4 0.0539606
RPS3 ribosomal protein S3 0.0536075
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0515695
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.051256
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0508903
ZNF292 zinc finger protein 292 0.0506894
ENO1 enolase 1, (alpha) 0.0503094
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0498918
RPS8 ribosomal protein S8 0.0484981
CCDC47 coiled-coil domain containing 47 0.0483395
AKAP12 A kinase (PRKA) anchor protein 12 0.048173
EIF4B eukaryotic translation initiation factor 4B 0.047355
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0467684
HMGB2 high mobility group box 2 0.0460967
PHF21A PHD finger protein 21A 0.0451284
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0449484
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0435719
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0422409
USP34 ubiquitin specific peptidase 34 0.0422024
MATR3 matrin 3 0.0416065
ZNF638 zinc finger protein 638 0.0405755
TPR translocated promoter region, nuclear basket protein 0.0398898
SCAF11 SR-related CTD-associated factor 11 0.0391486
RPL4 ribosomal protein L4 0.0390723
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0367517
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0364708
MARCHF6 membrane associated ring-CH-type finger 6 0.0350721
PGK1 phosphoglycerate kinase 1 0.0345802
RPL37A ribosomal protein L37a 0.0340849
DST dystonin 0.0340752
KIF5B kinesin family member 5B 0.0339007
FNDC3B fibronectin type III domain containing 3B 0.0337745
RAB6A RAB6A, member RAS oncogene family 0.0332105
SPAG9 sperm associated antigen 9 0.033093
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0330217
UBE3A ubiquitin protein ligase E3A 0.0329072
RNF130 ring finger protein 130 0.0328889
NAP1L1 nucleosome assembly protein 1-like 1 0.0322058
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0321096
RPLP1 ribosomal protein, large, P1 0.0318456
PNISR PNN-interacting serine/arginine-rich protein 0.0317395
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0315877
BZW1 basic leucine zipper and W2 domains 1 0.0315115
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0314273
RBM39 RNA binding motif protein 39 0.0313245
NSD3 nuclear receptor binding SET domain protein 3 0.0311291
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0310853
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0310276
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0306854
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0302766
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0301317
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.0297715
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0297714
GJA1 gap junction protein, alpha 1, 43kDa 0.02949
NIPBL Nipped-B homolog (Drosophila) 0.0293447
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0292135
TPT1 tumor protein, translationally-controlled 1 0.0292062
PDS5B PDS5 cohesin associated factor B 0.0291989
CKAP5 cytoskeleton associated protein 5 0.0291979
NUP58 nucleoporin 58 0.0291708
USP37 ubiquitin specific peptidase 37 0.0290474
NF1 neurofibromin 1 0.0290359
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0288221
XPO1 exportin 1 0.0287698
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0287594
TM9SF3 transmembrane 9 superfamily member 3 0.0286904
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0284698
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.0283663
TNPO1 transportin 1 0.0281912
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0281556
LARS1 leucyl-tRNA synthetase 1 0.0281182
RPS19 ribosomal protein S19 0.0280616
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0278063
RB1CC1 RB1-inducible coiled-coil 1 0.0277687
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0277222
TLK1 tousled-like kinase 1 0.0276813
MYH10 myosin, heavy chain 10, non-muscle 0.0273952
UBA2 ubiquitin-like modifier activating enzyme 2 0.0273521
CDC73 cell division cycle 73 0.0272942
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0272281
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0269239
RNF145 ring finger protein 145 0.0268761
SSH2 slingshot protein phosphatase 2 0.0266477
LPIN2 lipin 2 0.0265491
KDM6A lysine (K)-specific demethylase 6A 0.0262421
PRRC2C proline-rich coiled-coil 2C 0.0261324
WAC WW domain containing adaptor with coiled-coil 0.0260516

decreased expression

Symbol Name Standardized Value
TENM3 teneurin transmembrane protein 3 -0.178437
SLIT2 slit homolog 2 (Drosophila) -0.168005
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.155807
RAD51B RAD51 paralog B -0.0807709
NR5A2 nuclear receptor subfamily 5, group A, member 2 -0.0771337
NPAS3 neuronal PAS domain protein 3 -0.0626323
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0625966
HMGA1 high mobility group AT-hook 1 -0.0524769
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0513943
ATP11A ATPase, class VI, type 11A -0.0511085
ADGRG6 adhesion G protein-coupled receptor G6 -0.0509699
MLIP muscular LMNA-interacting protein -0.0492647
MCTP1 multiple C2 domains, transmembrane 1 -0.0488729
RPL11 ribosomal protein L11 -0.0440308
TBC1D32 TBC1 domain family, member 32 -0.0404188
ATP5F1B ATP synthase F1 subunit beta -0.0392785
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0386891
FOXO3 forkhead box O3 -0.0386488
TOX thymocyte selection-associated high mobility group box -0.0382752
LOC112694756 uncharaterized LOC112694756 -0.038001
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0374434
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.0372293
GRID2 glutamate receptor, ionotropic, delta 2 -0.0369431
PCNX4 pecanex 4 -0.0343302
EGR1 early growth response 1 -0.0338311
NEBL nebulette -0.0329873
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.0327642
ACTG1 actin gamma 1 -0.0322791
CADM2 cell adhesion molecule 2 -0.0310138
FMNL2 formin-like 2 -0.0297874
WLS wntless Wnt ligand secretion mediator -0.0296651
ZNF207 zinc finger protein 207 -0.0296069
SRSF3 serine/arginine-rich splicing factor 3 -0.0290696
FLNA filamin A, alpha -0.0282113
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0275543
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.027418
TTC28 tetratricopeptide repeat domain 28 -0.0272794
RIGI RNA sensor RIG-I -0.0270854
PFN1 profilin 1 -0.0267487
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -0.0266384
SERBP1 SERPINE1 mRNA binding protein 1 -0.0264316
POTEF POTE ankyrin domain family, member F -0.0262562
AGO2 argonaute RISC catalytic component 2 -0.0262558
PCBP2 poly(rC) binding protein 2 -0.0252832
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.0252063
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -0.0246674
FAT1 FAT atypical cadherin 1 -0.0246464
SOX4 SRY (sex determining region Y)-box 4 -0.0242694
RAB7A RAB7A, member RAS oncogene family -0.0240119
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0238931
RPS21 ribosomal protein S21 -0.0237989
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0237417
ZNFX1 zinc finger, NFX1-type containing 1 -0.0228795
BRD4 bromodomain containing 4 -0.0227064
LENG8 leukocyte receptor cluster (LRC) member 8 -0.0219104
TUBB4B tubulin, beta 4B class IVb -0.021487
HCFC1 host cell factor C1 -0.021454
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.0208669
RNASE12 ribonuclease, RNase A family, 12 (non-active) -0.0207968
PTCH1 patched 1 -0.0206422
VMP1 vacuole membrane protein 1 -0.0206374
CABIN1 calcineurin binding protein 1 -0.0205928
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0205607
VEGFC vascular endothelial growth factor C -0.0204268
RSU1 Ras suppressor protein 1 -0.0203214
TRIM25 tripartite motif containing 25 -0.0200541
GSE1 Gse1 coiled-coil protein -0.0198874
ZFP64 ZFP64 zinc finger protein -0.0195667
SMYD3 SET and MYND domain containing 3 -0.0194911
RBMX RNA binding motif protein, X-linked -0.0194724
EXT1 exostosin glycosyltransferase 1 -0.0193759
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.0191909
RFX7 regulatory factor X, 7 -0.0191361
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0189364
RPS15 ribosomal protein S15 -0.0188541
NUP98 nucleoporin 98kDa -0.0186755
FUS FUS RNA binding protein -0.0184369
ARMH4 armadillo like helical domain containing 4 -0.0184211
NR2C2 nuclear receptor subfamily 2, group C, member 2 -0.0183968
EEF2 eukaryotic translation elongation factor 2 -0.0182917
SALL4 spalt-like transcription factor 4 -0.0182261
ADAR adenosine deaminase, RNA-specific -0.0181562
SHROOM3 shroom family member 3 -0.0181559
MAGEA4 melanoma antigen family A4 -0.0181458
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0179084
TAPBP TAP binding protein (tapasin) -0.0179065
PRRC2A proline-rich coiled-coil 2A -0.0178731
CTPS1 CTP synthase 1 -0.0177719
PLCG1 phospholipase C, gamma 1 -0.0176163
MAP1B microtubule-associated protein 1B -0.0175416
KMT2D lysine (K)-specific methyltransferase 2D -0.0175114
ZNF544 zinc finger protein 544 -0.0174129
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0173714
TRRAP transformation/transcription domain-associated protein -0.0173648
CCNY cyclin Y -0.0173545
RAP1B RAP1B, member of RAS oncogene family -0.0173478
PRRC2B proline-rich coiled-coil 2B -0.0171143
PTPRS protein tyrosine phosphatase, receptor type, S -0.0169589
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0169144
CYB5R3 cytochrome b5 reductase 3 -0.0168794