Gallic acid (hydrate)_C32 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in C32 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.195662
VIM vimentin 0.168976
AKAP12 A kinase (PRKA) anchor protein 12 0.100458
ASPH aspartate beta-hydroxylase 0.100152
HILPDA hypoxia inducible lipid droplet-associated 0.0934777
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0895468
CD109 CD109 molecule 0.0876285
NAMPT nicotinamide phosphoribosyltransferase 0.0839639
ENO1 enolase 1, (alpha) 0.0809847
FMN1 formin 1 0.0787193
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0583326
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0569382
CALD1 caldesmon 1 0.0546711
TPR translocated promoter region, nuclear basket protein 0.0496702
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0486201
S100A6 S100 calcium binding protein A6 0.0474024
GDF15 growth differentiation factor 15 0.0455994
IGFBP3 insulin-like growth factor binding protein 3 0.0440079
TPT1 tumor protein, translationally-controlled 1 0.0408358
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0407884
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0405134
PTMA prothymosin, alpha 0.0401621
IGFBP5 insulin-like growth factor binding protein 5 0.03959
IFI16 interferon, gamma-inducible protein 16 0.0395695
PI15 peptidase inhibitor 15 0.03812
RPL37A ribosomal protein L37a 0.0378467
FMNL2 formin-like 2 0.0371939
TIMP3 TIMP metallopeptidase inhibitor 3 0.036958
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0363654
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0357536
RPS12 ribosomal protein S12 0.0352851
CANX calnexin 0.0351051
SFTPA2 surfactant protein A2 0.0347935
HLA-B major histocompatibility complex, class I, B 0.0347717
OXR1 oxidation resistance 1 0.034189
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0339122
ARHGAP5 Rho GTPase activating protein 5 0.0332425
GOLGA4 golgin A4 0.0326493
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.032341
CDC73 cell division cycle 73 0.0322727
DSTN destrin (actin depolymerizing factor) 0.0322541
PDIA3 protein disulfide isomerase family A, member 3 0.0320705
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0318954
NAP1L1 nucleosome assembly protein 1-like 1 0.0318789
CSNK1A1 casein kinase 1, alpha 1 0.031865
PRRC2C proline-rich coiled-coil 2C 0.0318004
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0313595
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0309678
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0305354
FRMD4A FERM domain containing 4A 0.0303496
RPS3 ribosomal protein S3 0.030142
DST dystonin 0.0298784
RPS2 ribosomal protein S2 0.029866
KTN1 kinectin 1 (kinesin receptor) 0.0296458
RPS8 ribosomal protein S8 0.029334
KMT2C lysine (K)-specific methyltransferase 2C 0.0292461
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0292238
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0287581
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.0285531
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0282395
ZNF292 zinc finger protein 292 0.0278805
B2M beta-2-microglobulin 0.027769
LDHA lactate dehydrogenase A 0.0272901
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0267934
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0266357
PGK1 phosphoglycerate kinase 1 0.0264725
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0263704
RTN4 reticulon 4 0.0263451
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0259873
JARID2 jumonji, AT rich interactive domain 2 0.0257579
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0256886
OGA O-GlcNAcase 0.0256563
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0255132
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0253661
EIF3A eukaryotic translation initiation factor 3, subunit A 0.025207
NPC1 Niemann-Pick disease, type C1 0.0252056
RPL26 ribosomal protein L26 0.0250142
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0249853
ERRFI1 ERBB receptor feedback inhibitor 1 0.024984
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0240042
VMP1 vacuole membrane protein 1 0.0238727
CENPF centromere protein F, 350/400kDa 0.0237644
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0237284
XPO1 exportin 1 0.0237029
PLIN2 perilipin 2 0.0235707
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0234377
GCC2 GRIP and coiled-coil domain containing 2 0.0230167
ESYT2 extended synaptotagmin-like protein 2 0.022578
CSDE1 cold shock domain containing E1, RNA-binding 0.0224819
AKAP9 A kinase (PRKA) anchor protein 9 0.0224699
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.022187
SET SET nuclear proto-oncogene 0.0221275
RO60 Ro60, Y RNA binding protein 0.0220732
RAB1A RAB1A, member RAS oncogene family 0.0220281
WSB1 WD repeat and SOCS box containing 1 0.0219132
DYNLT3 dynein, light chain, Tctex-type 3 0.0217795
RB1CC1 RB1-inducible coiled-coil 1 0.0215839
FBXO7 F-box protein 7 0.0213916
NFE2L1 nuclear factor, erythroid 2-like 1 0.0212468
CD63 CD63 molecule 0.021065

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.50649
FN1 fibronectin 1 -0.241306
MT2A metallothionein 2A -0.0881726
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0759334
EGR1 early growth response 1 -0.0578774
ICAM1 intercellular adhesion molecule 1 -0.0519837
LOC112694756 uncharaterized LOC112694756 -0.0516259
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0420022
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.0387721
FOSL1 FOS-like antigen 1 -0.0381361
ACTG1 actin gamma 1 -0.0360233
NPAS2 neuronal PAS domain protein 2 -0.0345193
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.033834
VGF VGF nerve growth factor inducible -0.0337315
NAV1 neuron navigator 1 -0.0327798
CHSY1 chondroitin sulfate synthase 1 -0.031917
NDRG1 N-myc downstream regulated 1 -0.0312845
CDK14 cyclin-dependent kinase 14 -0.0309839
POTEF POTE ankyrin domain family, member F -0.0304743
NAV2 neuron navigator 2 -0.0301672
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0291941
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0287646
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0283093
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0276383
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0273228
TAGLN2 transgelin 2 -0.0272113
RUNX1 runt-related transcription factor 1 -0.0268854
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -0.0260489
TPD52 tumor protein D52 -0.0259956
TNPO3 transportin 3 -0.0258881
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0250606
SGO2 shugoshin 2 -0.024027
TMEM178B transmembrane protein 178B -0.0237756
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0237486
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0234417
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0234256
RFX7 regulatory factor X, 7 -0.0229705
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.022896
AHNAK AHNAK nucleoprotein -0.0228015
FTH1 ferritin, heavy polypeptide 1 -0.0227183
NHSL1 NHS-like 1 -0.0226688
MACROD2 MACRO domain containing 2 -0.0222411
ANKRD28 ankyrin repeat domain 28 -0.022025
IGF2 insulin-like growth factor 2 -0.0214489
EHBP1 EH domain binding protein 1 -0.0209308
LOC102724023 ES1 protein homolog, mitochondrial -0.0208352
MEF2D myocyte enhancer factor 2D -0.0206433
NLGN1 neuroligin 1 -0.0203596
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0202605
HMCN1 hemicentin 1 -0.0201533
NAV3 neuron navigator 3 -0.0199897
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0198142
TMEM123 transmembrane protein 123 -0.0196306
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.0196286
TAPBP TAP binding protein (tapasin) -0.0195419
DOCK4 dedicator of cytokinesis 4 -0.0190952
STAU2 staufen double-stranded RNA binding protein 2 -0.0190824
PAX3 paired box 3 -0.0189389
CYB5R3 cytochrome b5 reductase 3 -0.018907
SCFD2 sec1 family domain containing 2 -0.0184804
SCLT1 sodium channel and clathrin linker 1 -0.0181196
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0178225
DYM dymeclin -0.0177818
TRRAP transformation/transcription domain-associated protein -0.0177791
ARHGAP6 Rho GTPase activating protein 6 -0.0172697
ETV6 ets variant 6 -0.0172113
CCNL1 cyclin L1 -0.0170324
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0167666
DIAPH2 diaphanous-related formin 2 -0.0166897
IFITM3 interferon induced transmembrane protein 3 -0.0165805
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0165448
SRPK2 SRSF protein kinase 2 -0.0164793
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0163895
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0163497
GANAB glucosidase, alpha; neutral AB -0.0160364
ATN1 atrophin 1 -0.0158808
MKI67 marker of proliferation Ki-67 -0.0156838
SND1 staphylococcal nuclease and tudor domain containing 1 -0.0156613
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 -0.0155946
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0152094
TM4SF1 transmembrane 4 L six family member 1 -0.015029
KIAA1549L KIAA1549-like -0.0150271
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.014947
FUS FUS RNA binding protein -0.0148276
NRP2 neuropilin 2 -0.014782
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0147553
CBFB core-binding factor, beta subunit -0.0146022
NRCAM neuronal cell adhesion molecule -0.01428
IFRD1 interferon-related developmental regulator 1 -0.0142245
NEGR1 neuronal growth regulator 1 -0.0141368
CTSD cathepsin D -0.014092
TNNC1 troponin C type 1 (slow) -0.013908
LPP LIM domain containing preferred translocation partner in lipoma -0.0138955
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0138234
RAP1B RAP1B, member of RAS oncogene family -0.0137495
KIF14 kinesin family member 14 -0.0137207
TMEM135 transmembrane protein 135 -0.0136781
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) -0.0136759
COG5 component of oligomeric golgi complex 5 -0.0136356
BHLHE40 basic helix-loop-helix family, member e40 -0.0136351