Gallic acid (hydrate)_CFPAC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SAMD4A sterile alpha motif domain containing 4A 0.0522207
SYNE2 spectrin repeat containing, nuclear envelope 2 0.044074
EFNA5 ephrin-A5 0.0349906
DST dystonin 0.0221794
RAD51B RAD51 paralog B 0.0218463
MAML2 mastermind-like 2 (Drosophila) 0.0191929
ZSWIM6 zinc finger, SWIM-type containing 6 0.0170474
NABP1 nucleic acid binding protein 1 0.0159959
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0158488
DOCK5 dedicator of cytokinesis 5 0.0157624
CMIP c-Maf inducing protein 0.0153272
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0151578
PCDH7 protocadherin 7 0.0144333
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0143657
PRELID2 PRELI domain containing 2 0.0136999
INTS6 integrator complex subunit 6 0.0132824
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0124953
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0119778
PDE4D phosphodiesterase 4D, cAMP-specific 0.0115609
TBC1D22A TBC1 domain family, member 22A 0.0114842
RNF213 ring finger protein 213 0.0108407
CEMIP cell migration inducing protein, hyaluronan binding 0.0107335
ATXN1 ataxin 1 0.0103745
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0100729
IFI44L interferon-induced protein 44-like 0.00957023
ZNF638 zinc finger protein 638 0.00956706
ZEB1 zinc finger E-box binding homeobox 1 0.00941071
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.00933736
PHF3 PHD finger protein 3 0.00905191
NALF1 NALCN channel auxiliary factor 1 0.0087875
DUOX2 dual oxidase 2 0.00867243
SLC35F5 solute carrier family 35, member F5 0.00843008
ANKRD36 ankyrin repeat domain 36 0.00841417
DAPK1 death-associated protein kinase 1 0.00838696
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.00818924
DPYD dihydropyrimidine dehydrogenase 0.00813105
RASEF RAS and EF-hand domain containing 0.00809822
CATSPERB catsper channel auxiliary subunit beta 0.00808951
VMP1 vacuole membrane protein 1 0.00792164
ANO6 anoctamin 6 0.00769014
DHFR dihydrofolate reductase 0.00764398
HDAC4 histone deacetylase 4 0.00753134
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.00751074
MYO9A myosin IXA 0.00736942
MBD5 methyl-CpG binding domain protein 5 0.00734044
SKI SKI proto-oncogene 0.00720735
FRMD6 FERM domain containing 6 0.00720525
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00682673
ADAM32 ADAM metallopeptidase domain 32 0.00676873
ANKRD36C ankyrin repeat domain 36C 0.00675446
FAAH2 fatty acid amide hydrolase 2 0.00673169
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.00670744
DNAH11 dynein, axonemal, heavy chain 11 0.00667831
CEP250 centrosomal protein 250kDa 0.00660412
EXOC4 exocyst complex component 4 0.0065969
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00647625
SKIL SKI-like proto-oncogene 0.00642161
PCLO piccolo presynaptic cytomatrix protein 0.00641052
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.0063716
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.00633915
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.0063192
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.00622181
CEP290 centrosomal protein 290kDa 0.0061381
PARP9 poly (ADP-ribose) polymerase family, member 9 0.00606837
SLTM SAFB-like, transcription modulator 0.00601647
ZBTB20 zinc finger and BTB domain containing 20 0.00598508
PRKCE protein kinase C, epsilon 0.00590458
LINC02210-CRHR1 LINC02210-CRHR1 readthrough 0.00587224
PTPRB protein tyrosine phosphatase, receptor type, B 0.0058295
NLK nemo-like kinase 0.005762
SMYD3 SET and MYND domain containing 3 0.00574981
CTBP2 C-terminal binding protein 2 0.00565957
SCAPER S-phase cyclin A-associated protein in the ER 0.00565632
RPS7 ribosomal protein S7 0.00561749
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.00558522
DOCK1 dedicator of cytokinesis 1 0.00558274
XRN1 5'-3' exoribonuclease 1 0.00557788
FER fer (fps/fes related) tyrosine kinase 0.00556698
EFCAB13 EF-hand calcium binding domain 13 0.00555435
MAML3 mastermind-like 3 (Drosophila) 0.0055212
WWOX WW domain containing oxidoreductase 0.00551168
TUT7 terminal uridylyl transferase 7 0.00549227
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00545651
KYNU kynureninase 0.00543219
BBS9 Bardet-Biedl syndrome 9 0.00542544
RIMKLB ribosomal modification protein rimK-like family member B 0.00540854
BABAM2 BRISC and BRCA1 A complex member 2 0.00536073
H2AC6 H2A clustered histone 6 0.00535522
SLK STE20-like kinase 0.0053399
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 0.00532837
DUSP10 dual specificity phosphatase 10 0.00524203
NRG3 neuregulin 3 0.0052065
ANKRD26 ankyrin repeat domain 26 0.00518566
AFDN afadin, adherens junction formation factor 0.00517157
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.00513851
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.00509123
DNAH5 dynein, axonemal, heavy chain 5 0.00508722
RASA3 RAS p21 protein activator 3 0.00505409
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.00504877
HMGA2 high mobility group AT-hook 2 0.00504749

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.280396
TMSB10 thymosin beta 10 -0.16618
PTMA prothymosin, alpha -0.160201
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.149263
ACTG1 actin gamma 1 -0.126664
MMP7 matrix metallopeptidase 7 -0.115564
HLA-B major histocompatibility complex, class I, B -0.104318
S100A6 S100 calcium binding protein A6 -0.0910721
EIF1 eukaryotic translation initiation factor 1 -0.0893359
LAMB3 laminin, beta 3 -0.0882056
POTEF POTE ankyrin domain family, member F -0.0880296
UBC ubiquitin C -0.0871402
KRT19 keratin 19, type I -0.0851871
TMSB4X thymosin beta 4, X-linked -0.0840378
FTH1 ferritin, heavy polypeptide 1 -0.0840195
NDRG1 N-myc downstream regulated 1 -0.0817042
B2M beta-2-microglobulin -0.0801607
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0749735
TM4SF1 transmembrane 4 L six family member 1 -0.0723631
HMGA1 high mobility group AT-hook 1 -0.0672617
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0626516
TPT1 tumor protein, translationally-controlled 1 -0.0611535
PKM pyruvate kinase, muscle -0.0582825
HLA-A major histocompatibility complex, class I, A -0.057508
ANXA2 annexin A2 -0.0570712
S100A10 S100 calcium binding protein A10 -0.0547859
FTL ferritin, light polypeptide -0.054283
VIM vimentin -0.0539447
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0538139
PGK1 phosphoglycerate kinase 1 -0.0536239
F3 coagulation factor III (thromboplastin, tissue factor) -0.0530859
IFI27 interferon, alpha-inducible protein 27 -0.051321
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0491605
ENO1 enolase 1, (alpha) -0.0490639
NAMPT nicotinamide phosphoribosyltransferase -0.048579
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0478254
RPL19 ribosomal protein L19 -0.0461161
IGFBP3 insulin-like growth factor binding protein 3 -0.046044
PLAU plasminogen activator, urokinase -0.0451991
CP ceruloplasmin (ferroxidase) -0.0444633
LY6E lymphocyte antigen 6 complex, locus E -0.0419742
RPLP1 ribosomal protein, large, P1 -0.0417265
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0409865
PLAT plasminogen activator, tissue -0.040783
RPL35A ribosomal protein L35a -0.0406432
LOC112694756 uncharaterized LOC112694756 -0.0401652
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0401624
NPEPPS aminopeptidase puromycin sensitive -0.0399288
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0395472
LDHA lactate dehydrogenase A -0.0394783
RPS24 ribosomal protein S24 -0.0392381
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0390805
GNAS GNAS complex locus -0.0388168
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.038389
RBM39 RNA binding motif protein 39 -0.0383189
TSC22D2 TSC22 domain family, member 2 -0.0380947
RPL34 ribosomal protein L34 -0.0373745
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0372708
TPM4 tropomyosin 4 -0.0368845
SLC38A1 solute carrier family 38, member 1 -0.0366641
ISG15 ISG15 ubiquitin-like modifier -0.0365265
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0359416
RPS8 ribosomal protein S8 -0.0359397
RPS23 ribosomal protein S23 -0.0357197
DSG2 desmoglein 2 -0.0346767
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0333412
EGR1 early growth response 1 -0.0332765
RTN4 reticulon 4 -0.0327474
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0325537
KPNB1 karyopherin (importin) beta 1 -0.0325326
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0321791
LMNA lamin A/C -0.0319897
RPL11 ribosomal protein L11 -0.0318989
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0315722
RAB1A RAB1A, member RAS oncogene family -0.0314206
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0313598
JUP junction plakoglobin -0.0311949
SPAG9 sperm associated antigen 9 -0.0311762
KRT8 keratin 8, type II -0.0310878
RPS21 ribosomal protein S21 -0.030858
AHNAK AHNAK nucleoprotein -0.030294
UBE2H ubiquitin-conjugating enzyme E2H -0.0302188
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0300845
RPS29 ribosomal protein S29 -0.0299233
TAGLN2 transgelin 2 -0.0296745
CNRIP1 cannabinoid receptor interacting protein 1 -0.0295884
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0295059
RPS6 ribosomal protein S6 -0.029365
CD2AP CD2-associated protein -0.0291656
UGCG UDP-glucose ceramide glucosyltransferase -0.0290389
S100A11 S100 calcium binding protein A11 -0.0290174
RIOK3 RIO kinase 3 -0.0287905
MAP1B microtubule-associated protein 1B -0.0287441
FOSL1 FOS-like antigen 1 -0.0287374
EZR ezrin -0.0286652
MT1X metallothionein 1X -0.0284545
TMEM123 transmembrane protein 123 -0.0279413
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0278694
FAM162A family with sequence similarity 162, member A -0.027529
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0274474