Gallic acid (hydrate)_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.235118
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0895342
FAM13A family with sequence similarity 13, member A 0.0827263
FNDC3B fibronectin type III domain containing 3B 0.0804858
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.0793142
HILPDA hypoxia inducible lipid droplet-associated 0.0556952
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0549782
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0517963
EXT1 exostosin glycosyltransferase 1 0.0491545
MSI2 musashi RNA-binding protein 2 0.0473272
DTNA dystrobrevin, alpha 0.042728
HELZ helicase with zinc finger 0.0400552
MEF2A myocyte enhancer factor 2A 0.0398911
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0382394
ASPH aspartate beta-hydroxylase 0.0382317
THSD4 thrombospondin, type I, domain containing 4 0.0358492
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0349303
RPL23 ribosomal protein L23 0.0346817
RPS12 ribosomal protein S12 0.0345127
PTMA prothymosin, alpha 0.0341882
PLAT plasminogen activator, tissue 0.0333982
CRH corticotropin releasing hormone 0.033299
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0332268
COPA coatomer protein complex, subunit alpha 0.0326944
PTPRD protein tyrosine phosphatase, receptor type, D 0.030853
VCL vinculin 0.0303415
SLITRK6 SLIT and NTRK-like family, member 6 0.0299847
UBA2 ubiquitin-like modifier activating enzyme 2 0.0296858
CCNY cyclin Y 0.0294561
APP amyloid beta (A4) precursor protein 0.029375
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.029011
RPL26 ribosomal protein L26 0.0289492
SOS1 son of sevenless homolog 1 (Drosophila) 0.0287934
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0287591
PSD3 pleckstrin and Sec7 domain containing 3 0.028655
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0284595
NRG1 neuregulin 1 0.0283097
NPAS2 neuronal PAS domain protein 2 0.0280707
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0279937
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0278349
AUTS2 autism susceptibility candidate 2 0.0276711
NDRG1 N-myc downstream regulated 1 0.0275413
PTK2 protein tyrosine kinase 2 0.0274875
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0273228
DDIT4 DNA-damage-inducible transcript 4 0.0269338
ENO1 enolase 1, (alpha) 0.0267744
GPBP1 GC-rich promoter binding protein 1 0.0266189
WAC WW domain containing adaptor with coiled-coil 0.0262552
USP34 ubiquitin specific peptidase 34 0.0261989
NALF1 NALCN channel auxiliary factor 1 0.0261502
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0259424
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0255784
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0253688
PHIP pleckstrin homology domain interacting protein 0.0249317
FERMT2 fermitin family member 2 0.0248185
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.024737
KMT2C lysine (K)-specific methyltransferase 2C 0.0245959
OGA O-GlcNAcase 0.0245884
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0245881
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0245556
SEPTIN2 septin 2 0.0241257
PCM1 pericentriolar material 1 0.0241053
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0240775
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0239098
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0238462
LMAN1 lectin, mannose-binding, 1 0.0236708
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0235472
TOP1 topoisomerase (DNA) I 0.0234255
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0233796
FXR1 fragile X mental retardation, autosomal homolog 1 0.0229624
MYH10 myosin, heavy chain 10, non-muscle 0.0228839
RSL1D1 ribosomal L1 domain containing 1 0.0227484
PARD3 par-3 family cell polarity regulator 0.0226502
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0226017
KMT2E lysine (K)-specific methyltransferase 2E 0.0220116
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0219477
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.021767
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0216112
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0215806
NIPBL Nipped-B homolog (Drosophila) 0.0215689
DNMBP dynamin binding protein 0.0214495
KDM3A lysine (K)-specific demethylase 3A 0.021196
NEK7 NIMA-related kinase 7 0.0210206
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0209052
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0206329
RBM26 RNA binding motif protein 26 0.0205862
SOX9 SRY (sex determining region Y)-box 9 0.0205737
ANKRD17 ankyrin repeat domain 17 0.0205614
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0205289
TIMP3 TIMP metallopeptidase inhibitor 3 0.0205162
LDHA lactate dehydrogenase A 0.0204673
ZFR zinc finger RNA binding protein 0.0204476
PTPRK protein tyrosine phosphatase, receptor type, K 0.0203279
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0202756
PICALM phosphatidylinositol binding clathrin assembly protein 0.0202693
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.0202573
ERRFI1 ERBB receptor feedback inhibitor 1 0.0201812
CSNK1G1 casein kinase 1, gamma 1 0.0201392
DST dystonin 0.0200988
ANKRD11 ankyrin repeat domain 11 0.019963

decreased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 -0.491772
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.200543
ACTG1 actin gamma 1 -0.0597258
COL1A1 collagen, type I, alpha 1 -0.0573102
SYT1 synaptotagmin I -0.0420524
RPL19 ribosomal protein L19 -0.0360188
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0354424
BPTF bromodomain PHD finger transcription factor -0.0348694
RPL38 ribosomal protein L38 -0.0284314
RPS15 ribosomal protein S15 -0.0270089
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.026993
BCAS3 breast carcinoma amplified sequence 3 -0.0263135
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0255403
GATA3 GATA binding protein 3 -0.0250123
PKM pyruvate kinase, muscle -0.0244946
RPL35A ribosomal protein L35a -0.0244377
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0239343
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0238395
EGR1 early growth response 1 -0.0236716
RPL13A ribosomal protein L13a -0.0235413
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0234419
TAPBP TAP binding protein (tapasin) -0.0223812
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0220671
MEF2D myocyte enhancer factor 2D -0.0218676
PDZRN3 PDZ domain containing ring finger 3 -0.020745
B2M beta-2-microglobulin -0.0206486
NCOR2 nuclear receptor corepressor 2 -0.0204471
TMSB10 thymosin beta 10 -0.0204207
DCAF7 DDB1 and CUL4 associated factor 7 -0.0204169
POTEF POTE ankyrin domain family, member F -0.0203958
RPS23 ribosomal protein S23 -0.0203439
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0200794
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0198325
FBXO28 F-box protein 28 -0.0196832
LSAMP limbic system-associated membrane protein -0.0191925
ATP5F1B ATP synthase F1 subunit beta -0.0189423
RC3H1 ring finger and CCCH-type domains 1 -0.018822
ZNFX1 zinc finger, NFX1-type containing 1 -0.0188134
NME2 NME/NM23 nucleoside diphosphate kinase 2 -0.0184441
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -0.0181751
RPL37A ribosomal protein L37a -0.0181383
CEP112 centrosomal protein 112kDa -0.0180864
RBM20 RNA binding motif protein 20 -0.0180857
PRKCA protein kinase C, alpha -0.0179813
PHOX2B paired-like homeobox 2b -0.0179112
PCNX2 pecanex 2 -0.0176645
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -0.0174377
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0174183
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0173765
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.0169381
TTC17 tetratricopeptide repeat domain 17 -0.0167743
NFIB nuclear factor I/B -0.0166822
NCOA7 nuclear receptor coactivator 7 -0.0159791
THBS1 thrombospondin 1 -0.0158249
DLC1 DLC1 Rho GTPase activating protein -0.0157957
XPO7 exportin 7 -0.0157807
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0157612
EIF1 eukaryotic translation initiation factor 1 -0.0157213
TGOLN2 trans-golgi network protein 2 -0.0156726
DEK DEK proto-oncogene -0.0156461
TTBK2 tau tubulin kinase 2 -0.0155505
EPHA6 EPH receptor A6 -0.0155149
SCLT1 sodium channel and clathrin linker 1 -0.0154323
LAMA5 laminin, alpha 5 -0.0152988
SCN9A sodium channel, voltage gated, type IX alpha subunit -0.0152323
CALD1 caldesmon 1 -0.0150745
AGO2 argonaute RISC catalytic component 2 -0.0150036
KDM5A lysine (K)-specific demethylase 5A -0.0149964
PCDH9 protocadherin 9 -0.0149692
RAB7A RAB7A, member RAS oncogene family -0.0149561
ZSWIM6 zinc finger, SWIM-type containing 6 -0.014912
LMNA lamin A/C -0.0148337
OLA1 Obg-like ATPase 1 -0.0147929
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0147382
RPS10 ribosomal protein S10 -0.0147136
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.0146852
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -0.0146499
ZRANB2 zinc finger, RAN-binding domain containing 2 -0.0146421
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0146042
RPS29 ribosomal protein S29 -0.0145758
TRPS1 trichorhinophalangeal syndrome I -0.0145337
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -0.0144634
RUNX1 runt-related transcription factor 1 -0.0144152
ZNF251 zinc finger protein 251 -0.0143095
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -0.014233
H1-0 H1.0 linker histone -0.0141096
NPAS3 neuronal PAS domain protein 3 -0.0139157
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0139112
ZNF652 zinc finger protein 652 -0.0138902
SMAD6 SMAD family member 6 -0.0136391
NRF1 nuclear respiratory factor 1 -0.0136325
COL6A1 collagen, type VI, alpha 1 -0.0135661
AVL9 AVL9 homolog (S. cerevisiase) -0.0135435
DNAAF9 dynein axonemal assembly factor 9 -0.0134999
RPS5 ribosomal protein S5 -0.0134904
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0134657
CYB5R3 cytochrome b5 reductase 3 -0.0134233
GLI3 GLI family zinc finger 3 -0.0133146
CENPE centromere protein E, 312kDa -0.0132912
HAND2 heart and neural crest derivatives expressed 2 -0.0132585