Gallic acid (hydrate)_H4 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in H4 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 0.19559
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0744907
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0744093
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0662873
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0348896
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0309934
DIAPH3 diaphanous-related formin 3 0.0297639
LDHA lactate dehydrogenase A 0.0294021
PDE4D phosphodiesterase 4D, cAMP-specific 0.0291295
PRELID2 PRELI domain containing 2 0.0286889
HDAC9 histone deacetylase 9 0.0274915
APLP2 amyloid beta (A4) precursor-like protein 2 0.0273358
TPM3 tropomyosin 3 0.0272481
KTN1 kinectin 1 (kinesin receptor) 0.0270893
PDIA3 protein disulfide isomerase family A, member 3 0.0265743
ZSWIM6 zinc finger, SWIM-type containing 6 0.0261677
ENO1 enolase 1, (alpha) 0.026024
CXCL8 chemokine (C-X-C motif) ligand 8 0.0253768
PDIA6 protein disulfide isomerase family A, member 6 0.0243406
EGFR epidermal growth factor receptor 0.0238562
INTS6 integrator complex subunit 6 0.0234287
PTPRD protein tyrosine phosphatase, receptor type, D 0.0223134
SDK1 sidekick cell adhesion molecule 1 0.0208178
PHF3 PHD finger protein 3 0.0199717
CENPF centromere protein F, 350/400kDa 0.0196271
ALCAM activated leukocyte cell adhesion molecule 0.0195005
ZNF395 zinc finger protein 395 0.0194535
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0194322
HYOU1 hypoxia up-regulated 1 0.0185468
RNF220 ring finger protein 220 0.0185019
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0183152
FNDC3B fibronectin type III domain containing 3B 0.0181349
FAM13A family with sequence similarity 13, member A 0.017314
PDLIM5 PDZ and LIM domain 5 0.0173112
TOP2A topoisomerase (DNA) II alpha 170kDa 0.017212
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0169066
ASPH aspartate beta-hydroxylase 0.0168541
ANO6 anoctamin 6 0.0168174
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0167298
NCAPG2 non-SMC condensin II complex, subunit G2 0.0160591
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0158519
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0157407
NFE2L1 nuclear factor, erythroid 2-like 1 0.0156
ATXN1 ataxin 1 0.0154493
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0154334
LIMCH1 LIM and calponin homology domains 1 0.0153364
CLU clusterin 0.0152875
HELZ helicase with zinc finger 0.0152748
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0149572
EGR1 early growth response 1 0.0149295
GLYATL2 glycine-N-acyltransferase-like 2 0.0148402
CEP128 centrosomal protein 128kDa 0.0148013
EEF1G eukaryotic translation elongation factor 1 gamma 0.01458
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.0143191
MIDEAS mitotic deacetylase associated SANT domain protein 0.0142729
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0141641
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 0.0141426
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.0141377
LAMP2 lysosomal-associated membrane protein 2 0.0140583
DSTN destrin (actin depolymerizing factor) 0.0140233
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.0139036
INSIG2 insulin induced gene 2 0.0137691
PLIN2 perilipin 2 0.0137684
POTEF POTE ankyrin domain family, member F 0.0135925
COL4A1 collagen, type IV, alpha 1 0.0135739
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0135696
FLRT2 fibronectin leucine rich transmembrane protein 2 0.0135311
CFAP96 cilia and flagella associated protein 96 0.0135219
KCTD16 potassium channel tetramerization domain containing 16 0.0135172
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0134737
MAGT1 magnesium transporter 1 0.0134289
SCAPER S-phase cyclin A-associated protein in the ER 0.0133241
PKM pyruvate kinase, muscle 0.0132011
RPS12 ribosomal protein S12 0.0130066
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0128813
E2F7 E2F transcription factor 7 0.012747
AKAP12 A kinase (PRKA) anchor protein 12 0.0127061
SFXN1 sideroflexin 1 0.0126936
EFNA5 ephrin-A5 0.0125576
DIAPH2 diaphanous-related formin 2 0.0125118
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0124115
CCPG1 cell cycle progression 1 0.0123575
PLAGL1 pleiomorphic adenoma gene-like 1 0.0123355
H1-2 H1.2 linker histone, cluster member 0.0123156
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0123122
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0122568
EXOC4 exocyst complex component 4 0.0122229
ZNF638 zinc finger protein 638 0.0122158
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.0121193
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.0120998
NLGN1 neuroligin 1 0.0120926
AKAP9 A kinase (PRKA) anchor protein 9 0.0120406
WWOX WW domain containing oxidoreductase 0.0120282
YBX1 Y box binding protein 1 0.0118825
DST dystonin 0.0118657
CHD1L chromodomain helicase DNA binding protein 1-like 0.0118518
MLEC malectin 0.0118198
SUMF1 sulfatase modifying factor 1 0.0117897
TPI1 triosephosphate isomerase 1 0.0117211
RPL21 ribosomal protein L21 0.0116473

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.110903
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.101377
COL6A3 collagen, type VI, alpha 3 -0.0939539
NALF1 NALCN channel auxiliary factor 1 -0.0904131
EXT1 exostosin glycosyltransferase 1 -0.0811314
TMSB10 thymosin beta 10 -0.0757044
HLA-B major histocompatibility complex, class I, B -0.07422
AHNAK AHNAK nucleoprotein -0.0651165
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0582702
HIPK2 homeodomain interacting protein kinase 2 -0.0563332
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0524769
CALU calumenin -0.0502689
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0495311
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0473403
RTN4 reticulon 4 -0.0454437
RRBP1 ribosome binding protein 1 -0.0438448
TPM4 tropomyosin 4 -0.0435545
IGF2 insulin-like growth factor 2 -0.0433241
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0431841
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -0.0402339
TPT1 tumor protein, translationally-controlled 1 -0.0401226
RAB7A RAB7A, member RAS oncogene family -0.0394962
APP amyloid beta (A4) precursor protein -0.0385448
ANTXR2 anthrax toxin receptor 2 -0.0382629
LOX lysyl oxidase -0.0382434
COL5A1 collagen, type V, alpha 1 -0.0379973
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.0361788
NAMPT nicotinamide phosphoribosyltransferase -0.0354993
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0354105
GARS1 glycyl-tRNA synthetase 1 -0.0353911
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.035229
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0350845
FTL ferritin, light polypeptide -0.0350125
NPAS2 neuronal PAS domain protein 2 -0.0345965
ANKRD11 ankyrin repeat domain 11 -0.0344911
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0344631
GNAS GNAS complex locus -0.0343129
PRSS23 protease, serine, 23 -0.0342052
GRB10 growth factor receptor-bound protein 10 -0.0334881
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0332769
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0325106
FAM20C family with sequence similarity 20, member C -0.0315387
PTK2 protein tyrosine kinase 2 -0.0314743
LMAN1 lectin, mannose-binding, 1 -0.0312512
ZFAND3 zinc finger, AN1-type domain 3 -0.0307523
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 -0.0302972
MARCHF6 membrane associated ring-CH-type finger 6 -0.0301483
HLA-C major histocompatibility complex, class I, C -0.0301104
HDLBP high density lipoprotein binding protein -0.0297999
TNS3 tensin 3 -0.029749
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0290925
ACTN4 actinin, alpha 4 -0.0287568
KPNB1 karyopherin (importin) beta 1 -0.0286986
KDM3A lysine (K)-specific demethylase 3A -0.0284158
SCFD2 sec1 family domain containing 2 -0.027627
GOLGA4 golgin A4 -0.027594
PXDN peroxidasin -0.0274854
ANKRD17 ankyrin repeat domain 17 -0.0274017
COPB1 coatomer protein complex, subunit beta 1 -0.0273245
NAV1 neuron navigator 1 -0.0271813
GLG1 golgi glycoprotein 1 -0.0270501
USP36 ubiquitin specific peptidase 36 -0.0261205
PTPRK protein tyrosine phosphatase, receptor type, K -0.0258128
TTC3 tetratricopeptide repeat domain 3 -0.0258072
LPP LIM domain containing preferred translocation partner in lipoma -0.0257393
RNF216 ring finger protein 216 -0.0257166
CLINT1 clathrin interactor 1 -0.0252357
TPTE transmembrane phosphatase with tensin homology -0.0251954
RAB1A RAB1A, member RAS oncogene family -0.0250651
NOP58 NOP58 ribonucleoprotein -0.0249662
S100A6 S100 calcium binding protein A6 -0.0245924
OSMR oncostatin M receptor -0.024315
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0242789
SDC4 syndecan 4 -0.0242469
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.0242152
CD99 CD99 molecule -0.0241243
CLMP CXADR-like membrane protein -0.0241234
CD63 CD63 molecule -0.0240349
MAP4 microtubule-associated protein 4 -0.0239422
PMM2 phosphomannomutase 2 -0.0237752
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0236249
EIF1 eukaryotic translation initiation factor 1 -0.0235689
HIBADH 3-hydroxyisobutyrate dehydrogenase -0.0234081
BIRC6 baculoviral IAP repeat containing 6 -0.0232677
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0229244
COL12A1 collagen, type XII, alpha 1 -0.0227521
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0226889
FSTL1 follistatin-like 1 -0.022629
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0225845
GCC2 GRIP and coiled-coil domain containing 2 -0.0225788
COL6A2 collagen, type VI, alpha 2 -0.0224541
CANX calnexin -0.0224538
SEC31A SEC31 homolog A (S. cerevisiae) -0.0224374
NIPBL Nipped-B homolog (Drosophila) -0.0222316
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0220315
MON2 MON2 homolog (S. cerevisiae) -0.021878
TMEM165 transmembrane protein 165 -0.0217881
TMEM41B transmembrane protein 41B -0.0217312
H3-3B H3.3 histone B -0.0216595
FOXJ3 forkhead box J3 -0.0216133